2016年8月
PREDICTIVE FACTORS FOR PROGNOSIS FOLLOWING UNSEDATED PERCUTANEOUS ENDOSCOPIC GASTROSTOMY IN ALS PATIENTS
MUSCLE & NERVE
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- 巻
- 54
- 号
- 2
- 開始ページ
- 277
- 終了ページ
- 283
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/mus.25051
- 出版者・発行元
- WILEY-BLACKWELL
Introduction: This study aimed to determine the prognostic factors and the values that predict survival after percutaneous endoscopic gastrostomy (PEG) tube placement in patients with amyotrophic lateral sclerosis (ALS). Methods: We retrospectively analyzed the correlations for 97 consecutive patients with ALS between clinical parameters and survival following PEG tube placement using the log-rank test and Cox proportional-hazards models. Results: The log-rank test showed that an arterial carbon dioxide pressure (PaCO2) of <= 40 mmHg (P = 0.0054), a forced vital capacity (FVC) of >= 38% of predicted (P = 0.0003), and bulbar-onset (P = 0.0121) were significantly associated with better post-PEG survival. Multivariate analysis showed that the FVC and PaCO2 were associated with better post-PEG survival (P = 0.0081 and P = 0.0265, respectively). Conclusions: PEG tube placement in ALS is recommended when FVC is >= 38% of predicted and when PaCO2 is normal.
- リンク情報
- ID情報
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- DOI : 10.1002/mus.25051
- ISSN : 0148-639X
- eISSN : 1097-4598
- PubMed ID : 26799526
- Web of Science ID : WOS:000383466400015