MISC

国際誌
2006年2月28日

Identification of thirty-four transcripts expressed specifically in hemocytes of Ciona intestinalis and their expression profiles throughout the life cycle.

DNA research : an international journal for rapid publication of reports on genes and genomes
  • Michio Ogasawara
  • ,
  • Noriko Nakazawa
  • ,
  • Kaoru Azumi
  • ,
  • Eiji Yamabe
  • ,
  • Nori Satoh
  • ,
  • Masanobu Satake

13
1
開始ページ
25
終了ページ
35
記述言語
英語
掲載種別
DOI
10.1093/dnares/dsi025
出版者・発行元
OXFORD UNIV PRESS

The innate immunity of ascidian hemocytes is considered to be a prototype of that in vertebrates. In this study, we identified as many transcripts as possible that were expressed specifically in hemocytes of Ciona intestinalis, a ubiquitous species of ascidian. Using a large-scale whole-mount in situ hybridization (WISH) technique and young adult specimens of C. intestinalis, 34 such transcripts were identified. Three of these appeared to encode immunity-related polypeptides, whereas 23 encoded hypothetical and/or new genes. Interestingly, different sets of transcripts appeared to be expressed in different subsets of hemocytes, as revealed by double-colored WISH. The 34 genes were categorized into two major subgroups based on their expression patterns during the C. intestinalis life cycle. Based on the gene expression profiles, we speculate that C. intestinalis hemocytes may exert more pleiotropic effects in immunity than previously believed.

リンク情報
DOI
https://doi.org/10.1093/dnares/dsi025
CiNii Articles
http://ci.nii.ac.jp/naid/80018994799
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/16766510
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000240077000003&DestApp=WOS_CPL
ID情報
  • DOI : 10.1093/dnares/dsi025
  • ISSN : 1340-2838
  • CiNii Articles ID : 80018994799
  • PubMed ID : 16766510
  • Web of Science ID : WOS:000240077000003

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