HOU De-Xing

J-GLOBAL         Last updated: Mar 15, 2018 at 18:01
HOU De-Xing
Kagoshima University
Faculty of Agriculture Biochemical Science and Technology
Job title
Associate Professor
Master degree in agriculture(Kagoshima University), Ph. D. in agriculture(Kagoshima University)

Research Areas


Academic & Professional Experience

Oct 2011
Professor, Kagoshima University
Nov 1997
Sep 2011
Associate Professor, Kagoshima University
Hunan Agriculture University, Research
Natiomal Children's Medical Research Center,


Science of Bioresource Production, The United Graduate School of Agricultral Science, Kagoshima University
Applied Animal Science, Graduate School, Division of Agricltural Sciences, Kagoshima University

Published Papers

The Biofunctions of Phytochemicals and Their Applications in Farm Animals: The Nrf2/Keap1 System as a Target
Qin S, Hou DX*
Engineering      Mar 2018   [Refereed]
Qin S, Hou DX*
Mol. Nutr. Food Res   60 1731-1755   Jul 2017   [Refereed]
Polyphenols from Lonicera caerulea L. Berry Inhibit LPS-induced Inflammation through Dual Modulation of Inflammatory and Antioxidant Mediators
Wu S, Yano S, Jihua Chen, Hisanaga A, Sakao K, He X, He J, Hou DX*
J. Agric. Food Chem   62(25) 5133-5141   May 2017   [Refereed]
Wu S, Yano S, Hisanaga A, He X, He J, Sakao K, Hou DX*
Mol Nutr Food Res   61(4) 2-9   Apr 2017   [Refereed]
DNA microarray profiling highlights Nrf2-mediated chemoprevention targeted by wasabi-derived isothiocyanates in HepG2 cells
Trio PZ, Kawahara A, Tanigawa S, Sakao K, Hou DX*
Nutr Cancer   69(1) 105-116   Jan 2017   [Refereed]
Hisanaga A, Mukai R, Sakao K, Terao J, Hou DX*
Mol Nutr Food Res   60(5) 1020-1032   May 2016   [Refereed]
Nguyen HT, Nguyen HT, Islam MZ, Obi T, Pothinuch P, Zar PP, Hou de X, Van Nguyen T, Nguyen TM, Van Dao C, Shiraishi M, Miyamoto A
J Ethnopharmacol.   182 16-26   Feb 2016   [Refereed]
Mukai R, Matsui N, Fujikura Y, Matsumoto N, Hou DX, Kanzaki N, Shibata H, Horikawa M, Iwasa K, Hirasaka K, Nikawa T, Terao J.
J Nutr Biochem   31 67-76   Jan 2016   [Refereed]
Wu SS, He X, Wu XS, Qin S, He JH, Zhang SR, Hou DX*
J Functional Foods   17 514-523   Mar 2015   [Refereed]
Sogo T, Terahara N, Hisanaga A, Kumamoto T, Yamashiro T, Wu S, Sakao K, Hou DX*.
Biofactors   41(1) 58-65   Jan 2015   [Refereed]
Sogo T, Kumamoto T, Ishida H, Hisanaga A, Sakao K, Terahara N, Wada K, Hou DX*
Planta Medica   81(1) 26-31   Jan 2015   [Refereed]
Abe N, Hou DX, Munemasa S, Murata Y, Nakamura Y
Cell Death Dis   5(e1534)    Oct 2014   [Refereed]
Hisanaga A, Ishida H, Sakao K, Sogo T, Kumamoto T, Hashimoto F and Hou DX*
Food & Function   5(8) 1891-1897   Aug 2014   [Refereed]
Qin S, Deng F, Wu W, Jiang L, Yamashiro T, Yano S and Hou DX*
Arch Biochem Biophys   559 53-61   Jul 2014   [Refereed]
Zar PPK, Moroshita A, Hashimoto F, Sakao K, Fujii M, Wada K and Hou DX*
J Functional Foods   6 523-533   Jul 2014   [Refereed]
Trio PZ, You SX, He X, He JH, Sakao K and Hou DX*
Food & Function   5(5) 833-844   May 2014   [Refereed]
You S, Nakanishi E, Kuwata H, Chen J, Nakasone Y, He X, He J, Liu X, Zhang S, Zhang B and Hou DX*
Mol Nutr Food Res   57(11) 2049-2060   Nov 2013   [Refereed]
Tanigawa S, Lee CH, Lin CS, Ku CC, Hasegawa H, Qin S, Kawahara A, Korenori Y,   Miyamori K, Noguchi M, Lee LH, Lin YC, Steve Lin CL, Nakamura Y, Jin C, Yamaguchi N, Eckner R, Hou DX*, Yokoyama KK*
Cell Death Dis   4(e921)    Oct 2013   [Refereed]
Korenori Y, Tanigawa S, Kumamoto T, Qin S, Miyamori K, Nagai M and Hou DX*
Mol Nutr Food Res   57(5) 854-864   May 2013   [Refereed]
91.Qin S, Chen J, Tanigawa S and Hou DX
Mol Nutr Food Res   57(3) 435-446   Mar 2013   [Refereed]
Qin S, Chen J, Tanigawa S, Hou DX
Journal of ethnopharmacology   140(1) 131-140   Mar 2012   [Refereed]
Hou DX, Korenori Y, Tanigawa S, Yamada-Kato T, Nagai M, He X, He J
Journal of agricultural and food chemistry   59(22) 11975-11982   Nov 2011   [Refereed]
Li LM, Hou DX, Guo YL, Yang JW, Liu Y, Zhang CY, Zen K
Journal of immunology (Baltimore, Md. : 1950)   186(4) 2552-2560   Feb 2011   [Refereed]
Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M, Hou DX
Nutrition and cancer   63(7) 1064-1073   2011   [Refereed]
Hou DX, Masuzaki S, Tanigawa S, Hashimoto F, Chen J, Sogo T, Fujii M
Journal of agricultural and food chemistry   58(24) 12735-12743   Dec 2010   [Refereed]
Hou DX, Kumamoto T
Antioxidants & redox signaling   13 691-719   Sep 2010   [Refereed]
Bian Z, Li LM, Tang R, Hou DX, Chen X, Zhang CY, Zen K
Cell research   20 1076-1078   Sep 2010   [Refereed]
Kumamoto T, Fujii M, Hou DX
Molecular and cellular biochemistry   332(1-2) 33-41   Dec 2009   [Refereed]
Sakao K, Fujii M, Hou DX
Bioscience, biotechnology, and biochemistry   73(9) 2048-2053   Sep 2009   [Refereed]
Yasuda M, Nishizawa T, Ohigashi H, Tanaka T, Hou DX, Colburn NH, Murakami A
Carcinogenesis   30 1209-1216   Jul 2009   [Refereed]
Sakao K, Fujii M, Hou DX
BioFactors (Oxford, England)   35 399-405   Jul 2009   [Refereed]
Kumamoto T, Fujii M, Hou DX
Cancer letters   275 17-26   Mar 2009   [Refereed]
Yang Y, Kitagaki J, Wang H, Hou DX, Perantoni AO
Cancer science   100(1) 24-28   Jan 2009   [Refereed]
Tanigawa S, Fujii M, Hou DX
Bioscience, biotechnology, and biochemistry   72(3) 797-804   Mar 2008   [Refereed]
Lin S, Fujii M, Hou DX
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association   46 590-597   Feb 2008   [Refereed]
Chen J, Uto T, Tanigawa S, Kumamoto T, Fujii M, Hou DX
Nutrition and cancer   60 Suppl 1 43-50   2008   [Refereed]
Hou DX, Luo D, Tanigawa S, Hashimoto F, Uto T, Masuzaki S, Fujii M, Sakata Y
Biochemical pharmacology   74 742-751   Sep 2007   [Refereed]
Hou DX, Masuzaki S, Hashimoto F, Uto T, Tanigawa S, Fujii M, Sakata Y
Archives of biochemistry and biophysics   460(1) 67-74   Apr 2007   [Refereed]
Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate.
Uto T, Fujii M, Hou DX
Oncology reports   17 233-238   Jan 2007   [Refereed]
Al-Dabbas MM, Suganuma T, Kitahara K, Hou DX, Fujii M
Journal of ethnopharmacology   108 287-293   Nov 2006   [Refereed]
Iwagawa T, Hashimoto K, Okamura H, Kurawaki J, Nakatani M, Hou DX, Fujii M, Doe M, Morimoto Y, Takemura K
Journal of natural products   69(8) 1130-1133   Aug 2006   [Refereed]
Yoshimoto M, Kurata-Azuma R, Fujii M, Hou DX, Ikeda K, Yoshidome T, Osako M
Bioscience, biotechnology, and biochemistry   69(9) 1777-1781   Sep 2005   [Refereed]
Hou DX, Tong X, Terahara N, Luo D, Fujii M
Archives of biochemistry and biophysics   440(1) 101-109   Aug 2005   [Refereed]
Trio PZ, Fujisaki S, Tanigawa S, Hisanaga A, Sakao K, Hou DX*
Gene Regul Syst Bio   10 73-83   [Refereed]


Archives of Biochemistry and Biophysics   428, 179-187    2004
Biochemical and Biophysical Research Communication   321, 539-546    2004
Baicalein induces apoptosis through ROS-mediated mitochondrial dysfunction pathway in HL-60 cells.
International Journal of Molecular Medicine   14, 627-632    2004

Books etc

Molecular Basis for Cancer Chemopreventive Effects of Anthocyans
HOU De-Xing
Lambert Academic Publishing   May 2012   

Conference Activities & Talks

A systematic project from animal meat production, meat processing, nutritional and functional assessment to human health [Invited]
HOU De-Xing
Food for Health International Conference 2017 (FOHIC2017)   18 Oct 2017   
plyphenols from Lonicera caerulea L. berry ameliorate experimental nonalcoholic steatohepatitis (NASH) through dual modulation of antioxidant and inflammatory mediators.
HOU De-Xing
8rn International Conference on Polyphenols and Health (ICPH2007)   5 Oct 2017   
DNA マイクロアレイから見えたイソチオシアネート化合物の生体調節機能
HOU De-Xing
第71回日本栄養・食糧学会大会   20 May 2017   
地域機能性食材を生かした「黒膳」食の研究開発 [Invited]
HOU De-Xing
西日本機能性食品開発研究会セミナー   19 May 2017   
Healthy benefits and application in kitchen table of anthocyanins-rich foods [Invited]
HOU De-Xing
7th Food Science, Biotechnology and Safety.   11 Nov 2016   


Function and Molecular Mechanisims of Non-Nutrients
HOU De-Xing   1999 - Today
Anti carcinogenic ability of purple sweet potato
Anti carcinogenic ability of blueberry and turmeric
Gene expression and regulation by functional food components

Research Grants & Projects

Signaling pathways for the inhibition of cell transformation by anthocyanins
Project Year: Apr 2006 - Mar 2008    Investigator(s): HOU De-Xing
Anti carcinogenic factors in natural food
Funded Research
Project Year: 1998   
Gene expression and regulation by food components
Project Year: 1998   
Transcription factors and gene expression
The Other Research Programs
Project Year: 1995   
Development of natural foods for Cancer Prevention