2009年8月
Variation in the safety of induced pluripotent stem cell lines
NATURE BIOTECHNOLOGY
- 巻
- 27
- 号
- 8
- 開始ページ
- 743
- 終了ページ
- 745
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1038/nbt.1554
- 出版者・発行元
- NATURE PUBLISHING GROUP
We evaluated the teratoma-forming propensity of secondary neurospheres (SNS) generated from 36 mouse induced pluripotent stem (iPS) cell lines derived in 11 different ways. Teratoma-formation of SNS from embryonic fibroblast-derived iPS cells was similar to that of SNS from embryonic stem (ES) cells. In contrast, SNS from iPS cells derived from different adult tissues varied substantially in their teratoma-forming propensity, which correlated with the persistence of undifferentiated cells.
- リンク情報
- ID情報
-
- DOI : 10.1038/nbt.1554
- ISSN : 1087-0156
- Web of Science ID : WOS:000268774500024