TAKAHASHI Akihisa


TAKAHASHI Akihisa

J-GLOBAL         Last updated: Jun 26, 2019 at 16:36
 
Avatar
Name
TAKAHASHI Akihisa
URL
http://heavy-ion.showa.gunma-u.ac.jp/
Affiliation
Gunma University
Job title
Professor
Degree
PhD(Kyoto University)

Research Areas

 
 

Academic & Professional Experience

 
2011
 - 
2015
Associate Proffesor: ASRLD Unit, Gunma University
 
2015
   
 
- Gunma University Heavy Ion Medical Center
 
2001
 - 
2010
Lecture: Department of Biology, Nara Medical University
 
1995
 - 
2001
Assistant Proffesor: Department of Biology, Nara Medical University
 
1991
 - 
1995
Otsuka Otsu Research Laboratories
 

Education

 
 
 - 
1991
Department of Biology, Faculty of Education, Tokyo Gakugei University
 
 
 - 
1989
Science of Secondary School Education Course, Faculty of Education, Tokyo Gakugei University
 

Committee Memberships

 
 
   
 
PTCOG Radiobiology Sub-committee  Vice President
 

Awards & Honors

 
2015
ICRR2015 Excellent Poster Award
 
2009
Abe Award from Japanese Society of Thermal Medicine
 
2009
Association Award from International Association for the Sensitization of Cancer Treatment
 
2008
Young Investigator Award from Radiation Effects Association
 
2005
Young Investigator Award from Japanese Society of Hyperthermic Oncology
 
2005
A Foundation of Saichi Nakajima Award from Nara Medical University School of Medicine
 
2001
Incentive Award from Japanese Association of Radiation Research Society
 
2000
Young Investigator Award from International Association for the Sensitization of Cancer Treatment
 
1998
Young Investigator Award from Japanese Association of Space Biology Science
 

Published Papers

 
Melatonin is a potential drug for the prevention of bone loss during space flight
Ikegame M, Hattori A, Tabata M, Kitamura K, Tabuchi Y, Furusawa Y, Maruyama Y, Yamamoto T, Sekiguchi T, Matsuoka R, Hanmoto T, Ikari T, Endo M, Omori K, Nakano M, Yashima S, Ejiri S, Taya T, Nakashima H, Shimizu N, Nakamura M, Kondo T, Hayakawa K, Takasaki I, Kaminishi A, Akatsuka R, Sasayama Y, Nishiuchi T, Nara M, Iseki H, Chowdhury VS, Wada S, Ijiri K, Takeuchi T, Suzuki T, Ando H, Matsuda T, Somei M, Mishima H, Mikuni-Takagaki Y, Funahashi H, Takahashi A, Watanabe Y, Maeda M, Uchida H, Hayashi A, Kambegawa A, Seki A, Yano S, Shimazu T, Suzuki H, Hirayama J, Suzuki N.
Journal of Pineal Research      Jun 2019
Effects of p53 status of tumor cells and combined treatment with mild hyperthermia, wortmannin or caffeine on recovery from radiation-induced damage
Shin-ichiro Masunaga, Keizo Tano, Yu Sanada, Minoru Suzuki, Akihisa Takahashi, Ken Ohnishi, Koji Ono
the World Journal of Oncology      Jun 2019   [Refereed]
Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation.
Hada M, Ikeda H, Rhone JR, Beitman AJ, Plante I, Souda H, Yoshida Y, Held KD, Fujiwara K, Saganti PB, Takahashi A.
International Journal of Molecular Science   20 43   Dec 2018   [Refereed][Invited]
Temporary loading prevents cancer progression and immune organ atrophy induced by hind-limb unloading in mice
Takahashi A, Wakihata S, Ma L, Adachi T, Hirose H, Yoshida Y, Ohira Y.
International Journal of Molecular Science   19 3959   Dec 2018   [Refereed][Invited]
Yoshida Y, Sejimo Y, Kurachi M, Ishizaki Y, Nakano T, Takahashi A.
Neurochemistry International   119 199-206   Oct 2018   [Refereed]
Heat induces histone γH2AX gormation under hypoxia
Yoshida Y, Tominaga S, Ma L, Takahashi A.
Thermal Medicine   34(3) 45-51   Sep 2018   [Refereed]
Nakagawa Y, Kajihara A, Takahashi A, Murata AS, Matsubayashi M, Ito SS, Ota I, Nakagawa T, Hasegawa M, Kirita T, Ohnishi T, Mori E.
International Journal of Hyperthermia   34(6) 795-801   Sep 2018   [Refereed]
Park SJ, Heo K, Choi C, Yang K, Adachi A, Okada H, Yoshida Y, Ohno T, Nakano T, Takahashi A.
Journal of Radiation Research   58(6) 765-771   Nov 2017   [Refereed]
Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A.
Life Sciences in Space Research   12 51-60   Feb 2017   [Refereed]
Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A.
Biological Science in Space   30 8-16   Dec 2016   [Refereed]

Misc

 
Role of high-linear energy transfer radiobiology in space radiation exposure risk
Akihisa Takahashi, Hiroko Ikeda, Yukari Yoshida
Int J Part Ther   5(1) 151   Nov 2018   [Refereed][Invited]
Held, Kathryn D.; Kawamura, Hidemasa; Kaminuma, Takuya; Paz, Athena Evalour S.; Yoshida, Yukari; Liu, Qi; Willers, Henning; Takahashi, Akihisa
FRONTIERS IN ONCOLOGY   6 23   2016   [Refereed][Invited]
Ota I, Okamoto N, Yane K, Takahashi A, Masui T, Hosoi H, Ohnishi T
Exp Ther Med   3(4) 585-591   Apr 2012   [Refereed]
Ohnishi T, Takahashi A, Suzuki H, Omori K, Shimazu T, Ishioka N.
Biol Sci Space.   23 3-10   2009   [Refereed]
Matsumoto H, Hamada N, Takahashi A, Kobayashi Y, Ohnishi T.
J Radiat Res   48 97-106   2007   [Refereed]

Books etc

 
Hyperthermic Oncology from Bench to Bedside (Chapter 9)
Springer   2016   
Hyperthermic Oncology from Bench to Bedside (Chapter 3)
Springer   2016   
Heat-induced DNA Damage (Cellular Response to Physical Stress and Therapeutic Application)
Nova Science Publishers, Inc   2013   
Encyclopedia of Cancer, 2nd Edition.
Springer.   2009   
Molecular Mechanisms for Radiation-induced Cellular Response and Cancer Development.
Institute for Environmental Sciences   2002   

Conference Activities & Talks

 
How to research about simulated space environments on the Earth [Invited]
TAKAHASHI Akihisa
International Conference on Mechanical, Electrical and Medical Intelligent System 2019 (ICMEMIS2019), Kiryu, Japan   4 Dec 2019   
Is gravity parameter necessary for cancer risk assessment in long-term manned space missions? [Invited]
Akihisa Takahashi
ISRBW2019, Dalian, China   30 Sep 2019   
Temporary Loading Prevents Cancer Progression and Immune Organ Atrophy Induced by Hind-limb Unloading
Akihisa Takahashi, Shoto Wakihata, Liqiu Ma, Takuya Adachi, Yukari Yoshida, Yoshinobu Ohira
ISTS2019, Fukui, Japan   19 Jun 2019   
Space Experiments for "Cancer Progression" in the International Space Station
Akihisa Takahashi, Masafumi Muratani, Asako Sawano, Atushi Miyawaki
ISGP2019, Nagoya, Japan   26 May 2019   
Gunma University Heavy Ion Medical Center (GHMC): Therapy and Space Research [Invited]
TAKAHASHI Akihisa
ICTSS2019, Kiryu, Japan   8 May 2019   
Future space experiments for “cancer risk assessment” in the ISS and the Gateway [Invited]
TAKAHASHI Akihisa
SMME2019, Kiryu, Japan   20 Mar 2019   
Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation.
Rhone JR, Beitman A, Ikeda H, Souda H, Yoshida Y, Held KD, Fujiwara K, Takahashi A, Saganti PB, Hada M.
2019 NASA Human Research Program Investigators' Workshop   Jan 2019   
The synergistic effect of simulated microgravity and charged particle radiation on gene expression in human fibroblasts.
Ikeda H, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y, *Takahashi A.
42nd COSPAR   Jul 2018   
Heat induces DNA double strand breaks under hypoxia
The 7th Asian Congress of Hyperthermic Oncology   2018   
Anti-tumor and anti-metastasis effects of carbon-ion radiotherapy combined with anti-CTLA4 antibody
PTCOG57   2018   

Research Grants & Projects

 
Acute Effects of Space Radiation with Different Radiation Qualities and Dose-rates
新学術領域研究(研究領域提案型)
Project Year: 2015 - 2019    Investigator(s): 髙橋昭久 群馬大学, 重粒子線医学推進機構, 教授 (60275336)
Elucidation of cancer invasion / metastasis mechanism associated with abnormal glucose metabolism and activation of EMT signaling in head and neck cancer
基盤研究(C)
Project Year: 2014 - 2016    Investigator(s): 太田 一郎 奈良県立医科大学, 医学部, 講師 (00326323)
Selection of DSBs repair pathways in heat-induced cell death mediated by BRCA2
基盤研究(C)
Project Year: 2014 - 2016    Investigator(s): 梶原 淳久 奈良県立医科大学, 医学部, 研究員 (00382317)
Elucidation of molecular mechanisms for radiation-induced cellular responses
JST Target Oriented Research for Embryonic Science and Technology (TOREST)
Project Year: 2011 - 2015
Biological effect of space radiation
Grant-in-Aid for Scientific Research
Project Year: 2015