Hirohisa Horinouchi

Profile Information

Affiliation: Associate Professor, School of Medicine, School of Medicine, Keio University

Degree: 医学博士(慶應義塾大学)

J-GLOBAL ID: 200901082032022396
researchmap Member ID: 1000263903

Research Areas

Research History

1993 - 1995

:ハーバード大学医学部、マサチューセッツ総合病院麻酔科細胞分子生物学教室研究員
1993 - 1995

:Research fellow, Devision of Cell and Molecular Biology, Department of Anesthesia and Critical Care Medicine, Massachusetts General Hospital, Harvard University, Medical School
1995

-:慶應義塾大学医学部外科学教室呼吸器外科研究室
1991 - 1993

:東京都立駒込病院
1991 - 1993

:Tokyo Metropolitan Komagome Hospital
1988 - 1991

:済生会神奈川県病院外科医員
1988 - 1991

:House staff、 Saiseikai Kanagawa Hospital
1985 - 1988

:慶應義塾大学医学部外科学教室肺外科研究室、専修医
1985 - 1988

:Resident, Division of Genaral Thoracic Surgery, Department of Surgery, School of Medicine, Keio University
1984 - 1985

:済生会神奈川県病院、専修医
1984 - 1985

:Resident、Saiseikai Kanagawa Hospital
1983 - 1984

:練馬総合病院へ出向、研修医
1983 - 1984

:Resident, Nerima General Hospital
1982 - 1983

:慶應義塾大学医学部外科学教室入局、慶応義塾大学病院研修医

Education

- 1982

Depertment of Medicine, School of Medicine, Keio University
- 1982

Faculty of Medicine, Keio University

Misc.

Exchange transfusion with synthetic oxygen-carrying plasma protein "albumin-heme" into an acute anemia rat model after seventy-percent hemodilution

T Komatsu, H Yamamoto, YB Huang, H Horinouchi, K Kobayashi, E Tsuchida

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 71A(4) 644-651, Dec, 2004
Exchange transfusion with synthetic oxygen-carrying plasma protein "albumin-heme" into an acute anemia rat model after seventy-percent hemodilution

T Komatsu, H Yamamoto, YB Huang, H Horinouchi, K Kobayashi, E Tsuchida

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 71A(4) 644-651, Dec, 2004
Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats

H Sakai, Y Masada, H Horinouchi, M Yamamoto, E Ikeda, S Takeoka, K Kobayashi, E Tsuchida

CRITICAL CARE MEDICINE, 32(2) 539-545, Feb, 2004
Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats

H Sakai, Y Masada, H Horinouchi, M Yamamoto, E Ikeda, S Takeoka, K Kobayashi, E Tsuchida

CRITICAL CARE MEDICINE, 32(2) 539-545, Feb, 2004
Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung

H Kato, K Furukawa, M Sato, T Okunaka, Y Kusunoki, M Kawahara, M Fukuoka, T Miyazawa, T Yana, K Matsui …

LUNG CANCER, 42(1) 103-111, Oct, 2003
Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung

H Kato, K Furukawa, M Sato, T Okunaka, Y Kusunoki, M Kawahara, M Fukuoka, T Miyazawa, T Yana, K Matsui …

LUNG CANCER, 42(1) 103-111, Oct, 2003
Analysis of angiogenic profiles by estimation of tumor blood flow with colored dye extraction microspheres after antiangiogenic therapy

A Iwamaru, M Watanabe, T Ohtsuka, H Horinouchi, K Kobayashi

ONCOLOGY REPORTS, 10(5) 1127-1131, Sep, 2003
Analysis of angiogenic profiles by estimation of tumor blood flow with colored dye extraction microspheres after antiangiogenic therapy

Arifumi Iwamaru, Masazumi Watanabe, Takashi Ohtsuka, Hirohisa Horinouchi, Koichi Kobayashi

Oncology Reports, 10(5) 1127-1131, Sep, 2003
Oxygenation of hypoxic region in solid tumor by administration of human serum albumin incorporating synthetic hemes.

堀之内宏久

J Biomed Mater Res., 64A(1) 48-51, 2003
気管食道領域の難治症例への対応＝良性気管・気管支狭窄の治療

堀之内宏久, 木下桂一, 藤本博行, 木村吉成, 小山孝彦, 神山育男, 後藤太一郎, 山本学, 井上芳正, 大塚崇 …

日本気管食道科学会・第13回認定医大会テキスト, 13 15-20, 2003
気管食道領域の難治症例への対応＝良性気管・気管支狭窄の治療

堀之内宏久, 木下桂一, 藤本博行, 木村吉成, 小山孝彦, 神山育男, 後藤太一郎, 山本学, 井上芳正, 大塚崇 …

日本気管食道科学会・第13回認定医大会テキスト, 13 15-20, 2003
高周波を用いた気道内病変の治療

堀之内宏久, 澤藤誠, 渡辺真純, 川村雅文, 小林紘一

呼吸, 22(2) 135-139, 2003
Pretreatment of serum containing hemoglobin vesicles (oxygen carriers) to prevent their interference in laboratory tests

堀之内宏久

Clin Chem Lab Med, 41(2) 222-231, 2003
Oxygenation of hypoxic region in solid tumor by administration of human serum albumin incorporating synthetic hemes

K Kobayashi, T Komatsu, A Iwamaru, Y Matsukawa, H Horinouchi, M Watanabe, E Tsuchida

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 64A(1) 48-51, Jan, 2003
Respiratory flow in a realistic tracheostenosis model

堀之内宏久

J Biomech Eng, 125(4) 461-471, 2003
A Case of sleeve resection of left main bronchus for bronchial mucoepidermoid carcinoma

KAMIYAMA Ikuo, HORINOUCHI Hirohisa, KIMURA Yoshishige, OYAMA Takahiko, GOTO Taichiro, YAMAMOTO Manabu, INOUE Yoshimasa, OHTSUKA Takashi, HORIGUCHI Hayanori, YAMAUCHI Tokuko …

The Journal of the Japanese Association for Chest Surgery, 17(6) 677-682, 2003
Oxygenation of hypoxic region in solid tumor by administration of human serum albumin incorporating synthetic hemes.

Kobayashi K, Komatsu T, Iwamaru A, Matsukawa Y, Horinouchi H, Watanabe M, Tsuchida E

J Biomed Mater Res., 64A(1) 48-51, 2003
Pretreatment of serum containing hemoglobin vesicles (oxygen carriers) to prevent their interference in laboratory tests

Sakai H, Tomiyama K, Masada Y, Takeoka S, Horinouchi H, Kobayashi K, Tsuchida E

Clin Chem Lab Med, 41(2) 222-231, 2003
Oxygenation of hypoxic region in solid tumor by administration of human serum albumin incorporating synthetic hemes

Kobayashi Kouichi, Komatsu Masao, Iwamaru Arifumi, Matsukawa, Watanabe Masazumi, Horinouchi Hirohisa, Tsuchida Eishun

Journal of biomedical material research, 64A(1) 48-51, 2003
Respiratory flow in a realistic tracheostenosis model

Sera T, Satoh S, Horinouchi H, Kobayashi K, Tanishita K

J Biomech Eng, 125(4) 461-471, 2003

Books and Other Publications

呼吸器研修医ノート第10章第4項腫瘍性疾患 (4)縦隔腫瘍

診断と治療社, 2004 (ISBN: 478781284X)
呼吸器研修医ノート第11章第3項代表的疾患の手術適応・術式・術後管理(1)肺癌肺切除術ー術後管理と合併症

診断と治療社, 2004 (ISBN: 478781284X)
呼吸器研修医ノート第11章第1項(2)開胸法

診断と治療社, 2004 (ISBN: 478781284X)
呼吸器研修医ノート

診断と治療社, 2004 (ISBN: 478781284X)

Presentations

408

難治性気管・気管支狭窄に対する治療：良性気管・気管支狭窄の治療

日本気管食道科学会・第13回認定医大会, 2003
浸潤性胸腺腫術後に重症筋無力症，赤芽球癆，脱毛を認めた症例

第22回日本胸腺研究会, 2003
浸潤性胸腺腫術後に重症筋無力症，赤芽球癆，脱毛を認めた症例

第22回日本胸腺研究会, 2003
結核性気管・気管支狭窄に対し，気管分岐部形成を行った一例

日本胸部外科学会関東甲信越地方会, 2003
Exchange transfusion of albumin-heme as an artificial oxygen carrier into anesthetized rats: physiological responces and oxygen delivery

International Symposium on blood substitutes, 2003
Pretrearment of blood serum containing Hb-Vesicles for accurate clinical laboratory tests

International Symposium on blood substitutes, 2003
Daily repeated infusion of Hb-vesicles (HbV) into wister rats for two weeks: a preliminary safety study

International Symposium on blood substitutes, 2003
Hemoglobin-Vescles as oxygen carriers: Influence on phagocytic activity and histopathological changes in reticuloendothelial system

International Symposium on blood substitutes, 2003
40% Blood exchange-transfusion with Hb-Vescles in rats and observation of hematological and serum clinical laboratory tests for 2 weeks

International Symposium on blood substitutes, 2003
Tumor oxygenation using the hemoprotein (rHSA-FeP) and the Hemoglobin- Vesicle (HbV) in a rat LY80 tumor model

International Symposium on blood substitutes, 2003
肺癌に対する気管支形成術の臨床的検討：現状と展望

第55回日本気管食道科学会, 2003
代謝系人工臓器・人工酸素運搬体のニューテクノロジー人工赤血球その機能,生体反応,安全性について

第41回日本人工臓器学会, 2003
若年者肺癌の臨床的検討

第44回肺癌学会総会, 2003
大血管・気道・食道のステント療法の問題点とその対策気管・気管支病変に対するIntervention ステントの占める役割

第56回日本胸部外科学会, 2003
Exchange transfusion of albumin-heme as an artificial oxygen carrier into anesthetized rats: physiological responces and oxygen delivery

International Symposium on blood substitutes, 2003
Pretrearment of blood serum containing Hb-Vesicles for accurate clinical laboratory tests

International Symposium on blood substitutes, 2003
Daily repeated infusion of Hb-vesicles (HbV) into wister rats for two weeks: a preliminary safety study

International Symposium on blood substitutes, 2003
Hemoglobin-Vescles as oxygen carriers: Influence on phagocytic activity and histopathological changes in reticuloendothelial system

International Symposium on blood substitutes, 2003
40% Blood exchange-transfusion with Hb-Vescles in rats and observation of hematological and serum clinical laboratory tests for 2 weeks

International Symposium on blood substitutes, 2003
Tumor oxygenation using the hemoprotein (rHSA-FeP) and the Hemoglobin- Vesicle (HbV) in a rat LY80 tumor model

International Symposium on blood substitutes, 2003

Profile Information

Research Areas

Research History

Education

Misc.

Books and Other Publications

Presentations

Works

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