Kashiwabara Shin-ichi

J-GLOBAL         Last updated: Dec 5, 2019 at 02:52
Kashiwabara Shin-ichi
University of Tsukuba
Faculty of Life and Environmental Sciences
Job title
Associate Professor

Research Areas



Second Cluster of College, University of Tsukuba
Graduate School, Division of Agriculture, University of Tsukuba

Published Papers

Kokubu, Daichi; Ooba, Ryousuke; Abe, Yukiko; Ishizaki, Hana; Yoshida, Shigeki; Asano, Atsushi; Kashiwabara, Shin-Ichi; Miyazaki, Hitoshi
Journal of Reproduction and Development   65(2) 139-146   Jan 2019   [Refereed]
<p>Recently, gradual decline in human sperm production has become a serious worldwide concern because it leads to increased rates of infertility. Endocrine disrupters, lifestyle changes, and varicocele, all of which elevate testicular temperature,...
Kashiwabara, Shin-Ichi; Tsuruta, Satsuki; Yamaoka, Yutaro; Oyama, Kanako; Iwazaki, Chieko; Baba, Tadashi
Journal of Reproduction and Development   64(1) 25-31   Feb 2018   [Refereed]
<p> Mutant mice lacking a testis-specific cytoplasmic poly(A) polymerase, PAPOLB/TPAP, exhibit spermiogenesis arrest and male infertility. However, the mechanism by which PAPOLB regulates spermiogenesis remains unclear. In this study, we examined ...
Journal of Reproduction and Development   62(6) 607-614   Dec 2016   [Refereed]
<p> The testis-specific cytoplasmic poly(A) polymerase PAPOLB/TPAP is essential for spermatogenesis. Although this enzyme is responsible for poly(A) tail extension of a subset of mRNAs in round spermatids, the stability and translational efficienc...
BIOLOGY OF REPRODUCTION      Apr 2013   [Refereed]
ACRBP/sp32 is a binding protein specific for the precursor
(pro-ACR) and intermediate forms of sperm serine protease ACR.
In this study, we examined the expression pattern, localization,
and possible role of mouse ACRBP in spermatogenic cells and
Development Growth and Differentiation   58(7) 600-608   Aug 2016   [Refereed]
Zfp318, a mouse gene with a Cys2/His2 zinc finger motif, is mainly expressed in germ cells in the testis. It encodes two alternative transcripts, which regulate androgen receptor-mediated transcriptional activation or repression by overexpression ...

Books etc

柏原真一;馬場, 忠 (Part:Supervisor)
実験医学   Apr 2003   
柏原真一;馬場, 忠 (Part:Supervisor)
日本疾患モデル学会誌   Jan 2004   
柏原真一 (Part:Supervisor)
生化学   Jan 2005   
Regulation of spermatogenesis by polyadenylation and deadenylation of mRNAs
Shin-ichi Kashiwabara; Tadashi Baba; (Part:Supervisor)
蛋白質核酸酵素・共立出版   Jan 2009   

Conference Activities & Talks

RNA-binding protein TB-RBP/Translin is involved in mRNA degradation
大山 可奈子;柏原 真一;馬場 忠
RNAフロンティアミーティング2018   19 Sep 2018   日本RNA学会
大山可奈子;柏原真一;馬場 忠
第20回日本RNA学会年会   9 Jul 2018   
Acrbp pre-mRNAの選択的スプライシング機構の解析
須郷卓也;相田千尋;兼森芳紀;柏原真一;馬場 忠
第41回日本分子生物学会年会   28 Nov 2018   
生殖細胞特異的Y-box RNA結合タンパク質による翻訳抑制機構
久恒, 翠;柏原, 真一;馬場, 忠
第40回日本分子生物学会年会   6 Dec 2017   
Functional analysis of RNA-binding protein TB-RBP
大山可奈子;柏原真一;馬場 忠
Gordon Research Conference on Fertilization and Activation of Development   Jul 2017   

Teaching Experience