Kashiwabara Shin-ichi

J-GLOBAL         Last updated: Dec 5, 2019 at 02:52
 
Avatar
Name
Kashiwabara Shin-ichi
E-mail
kashiwabara.shin.fwu.tsukuba.ac.jp
Affiliation
University of Tsukuba
Section
Faculty of Life and Environmental Sciences
Job title
Associate Professor

Research Areas

 
 

Education

 
 
 - 
1988
Second Cluster of College, University of Tsukuba
 
 
 - 
1993
Graduate School, Division of Agriculture, University of Tsukuba
 

Published Papers

 
Kokubu, Daichi; Ooba, Ryousuke; Abe, Yukiko; Ishizaki, Hana; Yoshida, Shigeki; Asano, Atsushi; Kashiwabara, Shin-Ichi; Miyazaki, Hitoshi
Journal of Reproduction and Development   65(2) 139-146   Jan 2019   [Refereed]
<p>Recently, gradual decline in human sperm production has become a serious worldwide concern because it leads to increased rates of infertility. Endocrine disrupters, lifestyle changes, and varicocele, all of which elevate testicular temperature,...
Kashiwabara, Shin-Ichi; Tsuruta, Satsuki; Yamaoka, Yutaro; Oyama, Kanako; Iwazaki, Chieko; Baba, Tadashi
Journal of Reproduction and Development   64(1) 25-31   Feb 2018   [Refereed]
<p> Mutant mice lacking a testis-specific cytoplasmic poly(A) polymerase, PAPOLB/TPAP, exhibit spermiogenesis arrest and male infertility. However, the mechanism by which PAPOLB regulates spermiogenesis remains unclear. In this study, we examined ...
Kashiwabara,Shin-ichi;Tsuruta,Satsuki;Okada,Keitaro;Yamaoka,Yutaro;Baba,Tadashi
Journal of Reproduction and Development   62(6) 607-614   Dec 2016   [Refereed]
<p> The testis-specific cytoplasmic poly(A) polymerase PAPOLB/TPAP is essential for spermatogenesis. Although this enzyme is responsible for poly(A) tail extension of a subset of mRNAs in round spermatids, the stability and translational efficienc...
Baba,Tadashi;Kanemori,Yoshinori;Ryu,Jin-Hyeob;Sudo,Mai;Niida-Araida,Yasushi;Kodaira,Kunihiko;Takenaka,Mika;Kohno,Nobuhisa;Sugiura,Shin;Kashiwabara,Shin-ichi
BIOLOGY OF REPRODUCTION      Apr 2013   [Refereed]
ACRBP/sp32 is a binding protein specific for the precursor
(pro-ACR) and intermediate forms of sperm serine protease ACR.
In this study, we examined the expression pattern, localization,
and possible role of mouse ACRBP in spermatogenic cells and
...
Ishizuka,,Masamichi;Ohtsuka,,Eri;Inoue,,Atsuto;Odaka,,Mirei;Ohshima,,Hirotaka;Tamura,,Norihisa;Yoshida,,Kaoru;Sako,,Norihisa;Baba,Tadashi;Kashiwabara,,Shin-ichi;Okabe,,Masaru;Noguchi,,Junko;Hagiwara,,Hiromi
Development Growth and Differentiation   58(7) 600-608   Aug 2016   [Refereed]
Zfp318, a mouse gene with a Cys2/His2 zinc finger motif, is mainly expressed in germ cells in the testis. It encodes two alternative transcripts, which regulate androgen receptor-mediated transcriptional activation or repression by overexpression ...

Books etc

 
精巣特異的ポリ(A)ポリメラーゼTPAPによる精子形態形成制御
柏原真一;馬場, 忠 (Part:Supervisor)
実験医学   Apr 2003   
精巣特異的ポリ(A)ポリメラーゼTPAPによる精子形態形成制御
柏原真一;馬場, 忠 (Part:Supervisor)
日本疾患モデル学会誌   Jan 2004   
半数体精細胞特異的遺伝子の発現制御
柏原真一 (Part:Supervisor)
生化学   Jan 2005   
Regulation of spermatogenesis by polyadenylation and deadenylation of mRNAs
Shin-ichi Kashiwabara; Tadashi Baba; (Part:Supervisor)
蛋白質核酸酵素・共立出版   Jan 2009   

Conference Activities & Talks

 
RNA-binding protein TB-RBP/Translin is involved in mRNA degradation
大山 可奈子;柏原 真一;馬場 忠
RNAフロンティアミーティング2018   19 Sep 2018   日本RNA学会
RNA結合タンパク質TB-RBPはmRNA分解に関与する
大山可奈子;柏原真一;馬場 忠
第20回日本RNA学会年会   9 Jul 2018   
Acrbp pre-mRNAの選択的スプライシング機構の解析
須郷卓也;相田千尋;兼森芳紀;柏原真一;馬場 忠
第41回日本分子生物学会年会   28 Nov 2018   
生殖細胞特異的Y-box RNA結合タンパク質による翻訳抑制機構
久恒, 翠;柏原, 真一;馬場, 忠
第40回日本分子生物学会年会   6 Dec 2017   
Functional analysis of RNA-binding protein TB-RBP
大山可奈子;柏原真一;馬場 忠
Gordon Research Conference on Fertilization and Activation of Development   Jul 2017   

Teaching Experience