Yuji Hiramatsu - My portal

Profile Information

Affiliation: Executive Director, University of Tsukuba, University of Tsukuba

Degree: Doctor of Philosophy in Medical Science(1997, University of Tsukuba)

Contact information: yuji3md.tsukuba.ac.jp
J-GLOBAL ID: 200901000790208577
researchmap Member ID: 1000267523

Research Interests

Research Areas

Life sciences / Cardiovascular surgery /

Research History

Nov, 2013 - Present

Professor, Faculty of Medicine, University of Tsukuba
Jan, 2006 - Oct, 2013

Associate professor, University of Tsukuba
Apr, 1998 - Dec, 2005

Assistant professor, University of Tsukuba
Jun, 2001 - Aug, 2001

アメリカ合衆国フィラデルフィア小児病院研修
May, 1996 - Mar, 1998

Cardiovasc surgery, Tsukuba memorial hospital
Jul, 1994 - Apr, 1996

post doctoral research fellow, University of Pennsylvania
Apr, 1992 - Jun, 1994

Cardiovasc surgery, Hitachi general hospital
Apr, 1986 - Mar, 1992

Surgical resident, University of Tsukuba hospital
Jun, 1990 - Mar, 1991

聖隷浜松総合病院心臓血管外科医員

Education

Apr, 1980 - Mar, 1986

Faculty of Medicine, University of Tsukuba

Committee Memberships

Awards

Jul, 1994

Medtronic Fellowship for Young Japanese Investigator, Japanese association of arrhythmia

Hiramatsu Yuji

Papers

223

Impairment of HIF-2α Expression Induced the Compensatory Overexpression of the HIF-1α/SDF-1 Axis to Promote Wound Healing

Yamashita, Toshiharu, Vuong, Cat-Khanh, Ngo, Nhat-Hoang, Osaka, Motoo, Hiramatsu, Yuji, Ohneda, Osamu

STEM CELLS AND DEVELOPMENT, 32(19-20) 592-605, Oct, 2023
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Edahiro, Ryuya, Shirai, Yuya, Takeshima, Yusuke, Sakakibara, Shuhei, Yamaguchi, Yuta, Murakami, Teruaki, Morita, Takayoshi, Kato, Yasuhiro, Liu, Yu-Chen, Motooka, Daisuke …

NATURE GENETICS, 55(5) 753-+, May, 2023 Peer-reviewed
Metabolically Healthy Obesity: Are Interventions Useful?

Mathis, Bryan J, Tanaka, Kiyoji, Hiramatsu, Yuji

CURRENT OBESITY REPORTS, 12(1) 36-60, Mar, 2023 Peer-reviewed
Myeloid Progenitor Inhibitory Factor-1 (CCL23) Inhibits Lung Leukocyte Recruitment in a Primate Cardiopulmonary Bypass-Induced Pulmonary Ischaemia Model

Goto, Yukinobu, Hiramatsu, Yuji, Ageyama, Naohide, Mathis, Bryan J, Maki, Naoki, Matsubara, Muneaki, Inoue, Yoshiaki, Sato, Yukio

Heart, lung & circulation, 32(3) 424-433, Mar, 2023 Peer-reviewedCorresponding author
Twisting of HeartMate II outflow graft 2.5 years after implantation-HM2 is still ongoing

Sakamoto, Hiroaki, Kato, Hideyuki, Tsukada, Toru, Mathis, Bryan J, Hiramatsu, Yuji

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, Feb, 2023 Peer-reviewed
Arterial switch operation with coronary button extension and neo-pulmonary trunk realignment for a rare coronary pattern

Yamaguchi, Akira, Kato, Hideyuki, Matsubara, Muneaki, Mathis, Bryan J, Hiramatsu, Yuji

JOURNAL OF CARDIAC SURGERY, 37(12) 5616-5618, Dec, 2022 Peer-reviewed
Induction of Cardiac Pathology: Endogenous versus Exogenous Nrf2 Upregulation

Mathis, Bryan J, Kato, Hideyuki, Hiramatsu, Yuji

CELLS, 11(23), Dec, 2022 Peer-reviewed
Endogenous and exogenous protection from surgically induced reactive oxygen and nitrogen species

Mathis, Bryan J, Kato, Hideyuki, Matsuishi, Yujiro, Hiramatsu, Yuji

Surgery today, Nov, 2022 Peer-reviewed
Pediatric delirium is associated with increased brain injury marker levels in cardiac surgery patients

Matsuishi, Yujiro, Hoshino, Haruhiko, Enomoto, Yuki, Shimojo, Nobutake, Matsubara, Muneaki, Kato, Hideyuki, Mathis, Bryan J, Morita, Kojiro, Hiramatsu, Yuji, Inoue, Yoshiaki

SCIENTIFIC REPORTS, 12(1), Nov, 2022 Peer-reviewed
TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility

Sekiya, Takeshi, Ogura, Yukino, Kai, Hirayasu, Kawaguchi, Atsushi, Okawa, Shino, Hirohama, Mikako, Kuroki, Takahiro, Morii, Wataru, Hara, Akira, Hiramatsu, Yuji …

FRONTIERS IN MICROBIOLOGY, 13, Nov, 2022 Peer-reviewed
Congenital Tricuspid Valve Calcification Necessitating Neonatal Surgical Intervention

Yamaguchi, Akira, Kato, Hideyuki, Matsubara, Muneaki, Mathis, Bryan J, Hiramatsu, Yuji

ANNALS OF THORACIC SURGERY, 114(3) E165-E167, Sep, 2022 Peer-reviewed
Factors of Obesity and Metabolically Healthy Obesity in Asia

Mathis, Bryan J, Tanaka, Kiyoji, Hiramatsu, Yuji

MEDICINA-LITHUANIA, 58(9), Sep, 2022 Peer-reviewed
DOCK2 is involved in the host genetics and biology of severe COVID-19

Namkoong, Ho, Edahiro, Ryuya, Takano, Tomomi, Nishihara, Hiroshi, Shirai, Yuya, Sonehara, Kyuto, Tanaka, Hiromu, Azekawa, Shuhei, Mikami, Yohei, Lee, Ho …

Nature, 609(7928) 754-760, Aug, 2022 Peer-reviewed
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Wang, Qingbo S, Edahiro, Ryuya, Namkoong, Ho, Hasegawa, Takanori, Shirai, Yuya, Sonehara, Kyuto, Tanaka, Hiromu, Lee, Ho, Saiki, Ryunosuke, Hyugaji, Takayoshi …

Nature communications, 13(1) 4830, Aug, 2022
Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues

Ngo, Nhat-Hoang, Chang, Yun-Hsuan, Khanh, Vuong Ca, Yamashita, Toshiharu, Obata-Yasuoka, Mana, Hamada, Hiromi, Osaka, Motoo, Hiramatsu, Yuji, Ohneda, Osamu

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 10, Aug, 2022 Peer-reviewed
Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway

Chang, Yun-Hsuan, Vuong, Cat-Khanh, Ngo, Nhat-Hoang, Yamashita, Toshiharu, Ye, Xiucai, Futamura, Yasunori, Fukushige, Mizuho, Obata-Yasuoka, Mana, Hamada, Hiromi, Osaka, Motoo …

Scientific reports, 12(1) 13550-13550, Aug, 2022
Type 2 Diabetes Mellitus Promotes the Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells into Cancer-Associated Fibroblasts, Induced by Breast Cancer Cells

Chang, Yun-Hsuan, Ngo, Nhat-Hoang, Khanh, Vuong Ca, Yamashita, Toshiharu, Osaka, Motoo, Hiramatsu, Yuji, Ohneda, Osamu

STEM CELLS AND DEVELOPMENT, 31(21-22) 659-671, Jul, 2022 Peer-reviewed
Conduction disorders after perimembranous ventricular septal defect closure: continuous versus interrupted suturing techniques

Yoneyama, Fumiya, Kato, Hideyuki, Matsubara, Muneaki, Mathis, Bryan J, Yoshimura, Yukihiro, Abe, Masakazu, Suetsugu, Fuminaga, Maruo, Kazushi, Suzuki, Yasuyuki, Hiramatsu, Yuji

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 62(1), Jun 15, 2022
Reply to Liu and Bu

Yoneyama, Fumiya, Kato, Hideyuki, Mathis, Bryan J, Hiramatsu, Yuji

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 62(1), Jun, 2022 Peer-reviewed
Successful surgical resection plus surgical cryoablation for the treatment of a large left ventricular fibroma

Yamamoto, Ryuhei, Matsubara, Muneaki, Kato, Hideyuki, Ishizu, Tomoko, Mathis, Bryan J, Hiramatsu, Yuji

Journal of cardiac surgery, 37(6) 1716-1717, Jun, 2022 Peer-reviewed

Books and Other Publications

救急外科手術アトラス

大坂基男, 平松祐司, Inoue, Yoshiaki (Role: Contributor, 四肢血管損傷の手術)

Sep, 2017
新・心臓血管外科テキスト

Hiramatsu, Yuji (Role: Contributor, 第３章小児心臓外科、2；心内修復術が目標となる非チアノーゼ性心疾患（７）先天性大動脈弁疾患)

中外医学社, 2016 (ISBN: 9784498039148)
新生児・乳児早期の体外循環と無輸血体外循環. 体外循環と補助循環

冨澤康子編集, 平松, 祐司

第25回日本人工臓器学会教育セミナーテキスト、日本人工臓器学会, Jul, 2009
病棟の看護ですぐに役立つ心臓病患者の「循環と呼吸」管理のポイント‐不整脈の管理‐

平松祐司, 阿部正一 (Role: Supervisor (editorial))

ハートナーシング, Jan, 2006
今日の循環器疾患治療指針第２版. 先天性心臓疾患

多数, 平松, 祐司

医学書院, Jan, 2001
循環器系の病理、循環器系の症候と病態生理. 臨床医学のMinimum Essential 第１版.

多数, 平松, 祐司

金原出版, Jan, 2000
続発性上皮小体機能亢進症をともなった透析患者の腹部大動脈瘤. 腹部大動脈瘤のすべて第１版

多数, 平松, 祐司

へるす出版, Jan, 1991

Presentations

147

筑波大学附属病院における医薬品の禁忌・適応外使用の把握

嶋田沙織, 中村舞美, 平松祐司, 本間真人, 和田, 哲郎

第18回医療の質・安全学会学術集会
Investigation of the molecular mechanism of BAV-associated aortopathy

Liu, Chang, Tokunaga, Chiho, Sugiyama, Kaori, Kimura, Kenichi, Tsukda, Toru, Kato, Hideyuki, Matsubara, Muneaki, Osaka, Motoo, Sakamoto, Hiroaki, Matsunaga, Hiroko, Takeyama, Haruko, Yanagisawa, Hiromi, Hiramatsu, Yuji

The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery
上腸間膜動脈閉塞と広範囲腸管壊死を合併した Stanford A 型急性大動脈解離の一救命例

幸寺巴香, 徳永千穂, 佐々木花恵, 安岡健太, 今中佑紀, 山嵜肇, 塚田亨, 加藤秀之, 松原宗明, 五味聖吾, 大坂基男, 坂本裕昭, 橋本真治, 榎本剛史, 小田, 竜也, 平松祐司

第253回茨城外科学会
当院における腹部大動脈瘤破裂に対する治療成績の検討

山嵜, 肇, 大坂, 基男, 今中, 佑紀, 梶, 翔馬, 山本, 隆平, 鈴木, 一史, 塚田, 亨, 加藤, 秀之, 松原, 宗明, 徳永, 千穂, 坂本, 裕昭, 平松, 祐司

第53回日本心臓血管外科学会学術総会
早期・中期成績を考慮した急性大動脈解離に対する治療戦略の検討

鈴木, 一史, 大坂, 基男, 今中, 佑紀, 山嵜, 肇, 梶, 翔馬, 塚田, 亨, 加藤, 秀之, 松原, 宗明, 徳永, 千穂, 坂本, 裕昭, 平松, 祐司

第53回日本心臓血管外科学会学術総会
周術期管理に難渋した成人期 Fontan 手術の 1 例

山嵜, 肇, 松原, 宗明, 今中, 佑紀, 梶, 翔馬, 鈴木, 一史, 塚田, 亨, 加藤, 秀之, 徳永千穂, 五味, 聖吾, 大坂, 基男, 坂本, 裕昭, 平松, 祐司

第191回日本胸部外科学会関東甲信越地方会
TOF術後遠隔期の難治性上室性不整脈に心外膜アブレーションが奏効した1例

今中佑紀, 松原, 宗明, 梶, 翔馬, 山嵜, 肇, 山本, 隆平, 鈴木, 一史, 塚田, 亨, 加藤, 秀之, 徳永, 千穂, 大坂, 基男, 坂本, 裕昭, 平松, 祐司

第190回日本胸部外科学会関東甲信越地方会
体外式膜型人工肺（ECMO）内に生ずる血栓の原因を探る〜模擬体外循環時に増加する脱シアル化血小板の機能解析〜

鈴木, 保之, 荒尾ほほみ, 登尾一平, 古垣達也, 田邊香野, 川口辰哉, 平松祐司, 上妻行則

第60回日本人工臓器学会大会
Mid-term results of pulmonary artery valve replacement in Adult patients after repair of congenital heart disease

山本, 隆平, 松原, 宗明, 今中, 佑紀, 山嵜, 肇, 鈴木, 一史, 塚田, 亨, 加藤, 秀之, 徳永千穂, 大坂, 基男, 坂本, 裕昭, 平松, 祐司

第75回日本胸部外科学会定期学術集会
Early and mid-term results of hybrid TEVAR

大坂, 基男, 塚田, 亨, 鈴木, 一史, 山嵜, 肇, 今中, 佑紀, 山本, 隆平, 加藤, 秀之, 松原, 宗明, 徳永, 千穂, 坂本, 裕昭, 平松, 祐司

The 75th annual scientific meeting of the Japanese Association of Thoracic Surgery
医学部2年生を対象とした心臓外科講義におけるTBL導入の試み

松原, 宗明, 木村, 友和, 前野, 貴美, 加藤, 秀之, 平松, 祐司

第9回Surgical Education Summit
ワルファリン服用患者におけるトラマドールの併用がINRに及ぼす影響(第5報)

花井誠, 細野智美, 家田真樹, 松本功, 平松祐司, 山崎正志, 関堂充, 神林泰行, 本間, 真人

第30回クリニカルファーマシーシンポジウム
Perioperative MRSA Infection Control in Pediatric Cardiac Surgery

今中, 佑紀, 松原, 宗明, 梶, 翔馬, 山嵜, 肇, 山本, 隆平, 加藤秀之, 平松祐司

第58回日本小児循環器学会総会
Blood Flow Analysis of Fontan Pathway using Computer Fluid Simulation in Apicocaval Juxtraposition

山嵜, 肇, 松原, 宗明, 今中, 佑紀, 梶, 翔馬, 山本, 隆平, 加藤, 秀之, 平松, 祐司

第58回日本小児循環器学会総会
Risk Factors for Prolonged Pleural Effusion after Total Cavopulmonary Connection

山本, 隆平, 松原, 宗明, 今中, 佑紀, 山嵜, 肇, 梶, 翔馬, 加藤, 秀之, 平松, 祐司

第191回日本胸部外科学会関東甲信越地方会
当院における大動脈解離再手術症例の検討

大坂, 基男, 塚田, 亨, 鈴木, 一史, 山嵜, 肇, 今中, 佑紀, 山本, 隆平, 加藤, 秀之, 松原, 宗明, 徳永, 千穂, 坂本, 裕昭, 平松, 祐司

第50回日本血管外科学会定期学術総会
遺残解離拡大に対する胸腹部大動脈置換術後にaortic stiffnessの上昇から大動脈基部拡大を来し短期間で全大動脈置換術になった1例

山嵜, 肇, 大坂, 基男, 山口, 章, 梶, 翔馬, 山本, 隆平, 鈴木, 一史, 塚田, 亨, 加藤, 秀之, 松原, 宗明, 徳永, 千穂, 坂本, 裕昭, 平松, 祐司

第50回日本血管外科学会定期学術総会
未承認薬等の把握のための分類表の作成とその活用

嶋田, 沙織, 中村, 舞美, 髙嶋, 泰之, 山口, 剛, 鶴嶋, 英夫, 和田, 哲郎, 本間, 覚, 平松, 祐司, 本間, 真人

第16回医療の質・安全学会学術集会, Nov 27, 2021
Chronic type B aortic dissection resulting in ruptured artificial blood vessel from contact with the rib stump after descending aorta replacement: a case report

立石, 綾, 大坂, 基男, 井口裕介, 園部藍子, 石井知子, 塚田, 亨, 加藤, 秀之, 松原, 宗明, 五味, 聖吾, 上西, 祐一朗, 坂本, 裕昭, 平松, 祐司

第74回日本胸部外科学会定期学術集会, Oct 31, 2021, 日本胸部外科学会
Cerebral Infarction in Patients Undergoing Debranching Thoracic Endovascular Aneurysm Repair

大坂, 基男, 山口, 章, 山嵜, 肇, 山本, 隆平, 鈴木, 一史, 中嶋, 智美, 塚田, 亨, 加藤, 秀之, 松原, 宗明, 坂本, 裕昭, 平松, 祐司

第74回日本胸部外科学会定期学術集会, Oct 31, 2021, 日本胸部外科学会

Professional Memberships

1988 - Present

THE JAPANESE ASSOCIATION FOR THORACIC SURGERY
1986 - Present

Japan Surgical Society
- Present

Congenital Heart Surgeons' Society 東日本
- Present

Congenital Heart Surgeons' Society Japan
- Present

Society of Thoracic Surgeons
- Present

American Heart Association
- Present

The Ichthyological Society of Japan
- Present

JAPANESE HEART RHYTHM SOCIETY
- Present

日本静脈学会
- Present

THE JAPAN SOCIETY FOR ARTIFICIAL ORGANS
- Present

JAPANESE COLLEGE OF CARDIOLOGY
- Present

THE JAPANESE SOCIETY FOR CARDIOVASCULAR SURGERY
- Present

JAPANESE SOCIETY OF PEDIATRIC CARDIOLOGY AND CARDIAC SURGERY
- Present

JAPANESE SOCIETY OF PEDIATRIC SURGEONS
- Present

JAPANESE SOCIETY FOR VASCULAR SURGERY

Research Projects

Development and evaluation of MK-7 free fermented soy-bean using short-term incubation and ultraviolet radiation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2016 - 2018

Hiramatsu Yuji
ベトナム・チョーライ病院における短期国際医療交流体験型クリニカル・クラークシップ

海外留学支援制度（短期派遣）, 日本学生支援機構, 2014 - 2015

平松祐司
Development of MK-7 free fermented soy-bean-like food using ultraviolet

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2013 - 2015

Hiramatsu Yuji, KITAMURA Yutaka, HASEGAWA Yuichi, HORIGOME Hitoshi
Combined anticoagulation protocol using TFPI, antithrombin and thrombomodulin during cardiopulmonary bypass

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2011 - 2014

HIRAMATSU Yuji, AGEYAMA Naohide, SAKAKIBARA Yuzuru, HASEGAWA Yuichi, GOTO Yukinobu
低分子量エポキシ化合物TGA固定自己心膜の心血管補填材料としての適性に関する研究

挑戦的萌芽研究, 日本学術振興会, 2011 - 2013

後藤行延
Development of MK-7 free fermented soy-bean-like food

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

HIRAMATSU Yuji, KITAMURA Yutaka, HASEGAWA Yuichi, HORIGOME Hitoshi
白血球の複合的薬理制御による体外循環後肺傷害に対する新たな予防法の開発

基盤研究(B), 日本学術振興会, 2009 - 2012

後藤行延
ベトナム医学研究における臨床と基礎をつなぐ橋渡し支援事業

若手研究者招聘事業, 日本学術振興会, 2011 - 2011

山田信博
Pharmacological control of soluble tissue factor and monocyte for the inhibition of the extrinsic coagulation pathway during cardiopulmonary bypass in monkeys

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2008 - 2010

HIRAMATSU Yuji, AGEYAMA Naohide, SAKAKIBARA Yuzuru, HASEGAWA Yuichi, TOKUNAGA Chiho
Role of Heparin Induced Tissue Factor Pathway Inhibitor Release in Attenuation of Tissue Factor-Dependent Thrombin Generation During Cardiopulmonary Bypass

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2006 - 2007

HIRAMATSU Yuji, AGEYAMA Naohide, SAKAKIBARA Yuzuru
スポーツ活動が小児の血小板・血管内皮機能と動脈硬化の進展に及ぼす効果に関する研究

基盤研究(C), 日本学術振興会, 2003 - 2005

堀米仁志

Industrial Property Rights

PCT/JP2016/62062 ポリ（Ｌ−アルギニン）セグメント含有ブロック共重合体とポリアニオン性ポリマーのポリイオンコンプレックス

工藤, 心平, 平松祐司, 坂本裕昭, ブイクオタン, ボンビンロン, 長崎, 幸夫