冨田謙吾 (Kengo Tomita) - マイポータル

基本情報

所属: 防衛医科大学校消化器内科准教授

J-GLOBAL ID: 200901014629106137
researchmap会員ID: 5000065642

研究キーワード

経歴

2017年4月 - 現在

防衛医科大学校, 消化器内科, 准教授

学歴

1995年4月 - 1999年3月

慶應義塾大学大学院医学研究科博士課程
1987年4月 - 1993年3月

慶應義塾大学, 医学部

受賞

論文

Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids.

Yoshihiro Akita, Masaaki Higashiyama, Chie Kurihara, Suguru Ito, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Rina Tanemoto, Nao Sugihara, Yoshinori Hanawa …

Digestive diseases and sciences 1-11 2022年12月7日
Transgenerational impacts of oral probiotic administration in pregnant mice on offspring gut immune cells and colitis susceptibility.

Yoshikiyo Okada, Nao Sugihara, Shin Nishii, Suguru Itoh, Akinori Mizoguchi, Rina Tanemoto, Kazuki Horiuchi, Akira Tomioka, Hiroyuki Nishimura, Masaaki Higashiyama …

Journal of gastroenterology and hepatology 2022年11月8日
Basophils play a proinflammatory role in oxazolone-induced chronic intestinal inflammation.

Kenichi Inaba, Masaaki Higashiyama, Chikako Watanabe, Akira Tomioka, Suguru Ito, Rina Tanemoto, Akinori Mizoguchi, Shin Nishii, Akinori Wada, Nao Sugihara …

Journal of gastroenterology and hepatology 2022年7月25日査読有り
Changes in Colonic Inflammation Related with Takayasu Arteritis during a 10-year Observation Period.

Akinori Wada, Masaaki Higashiyama, Dai Hirata, Suguru Ito, Rina Tanemoto, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa …

Internal medicine (Tokyo, Japan) 2021年8月13日査読有り
Acesulfame potassium induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa.

Yoshinori Hanawa, Masaaki Higashiyama, Chie Kurihara, Rina Tanemoto, Suguru Ito, Akinori Mizoguchi, Shin Nishii, Akinori Wada, Kenichi Inaba, Nao Sugihara …

Journal of gastroenterology and hepatology 36(11) 3140-3148 2021年8月8日査読有り
Novel probiotic yeast from Miso promotes regulatory dendritic cell IL-10 production and attenuates DSS-induced colitis in mice

Yoshikiyo Okada, Yoshikazu Tsuzuki, Nao Sugihara, Shin Nishii, Naoki Shibuya, Akinori Mizoguchi, Suguru Itoh, Rina Tanemoto, Kenichi Inaba, Yoshinori Hanawa …

Journal of Gastroenterology 56(9) 829-842 2021年7月2日査読有り
Angiopoietin‐like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells

Toshiaki Teratani, Kengo Tomita, Akinori Wada, Nao Sugihara, Masaaki Higashiyama, Kenichi Inaba, Kazuki Horiuchi, Yoshinori Hanawa, Shin Nishii, Akinori Mizoguchi …

Hepatology Research 51(5) 580-592 2021年5月査読有り筆頭著者責任著者
Deoxycholic acid enhancement of lymphocyte migration through direct interaction with the intestinal vascular endothelium

Naoki Shibuya, Masaaki Higashiyama, Yoshihiro Akita, Kazuhiko Shirakabe, Suguru Ito, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Rina Tanemoto, Nao Sugihara …

Journal of Gastroenterology and Hepatology 36(9) 2523-2530 2021年4月14日査読有り
Intestinal inflammations increase efflux of innate lymphoid cells from the intestinal mucosa to the mesenteric lymph nodes through lymph‐collecting ducts

Kazuki Horiuchi, Masaaki Higashiyama, Chie Kurihara, Kouji Matsumura, Rina Tanemoto, Suguru Ito, Akinori Mizoguchi, Shin Nishii, Akinori Wada, Kenichi Inaba …

Microcirculation 28(5) e12694 2021年3月28日査読有り
Clinical characteristics of immunoglobulin IgG4-related sclerosing cholangitis: Comparison of cases with and without autoimmune pancreatitis in a large cohort

Itaru Naitoh, Terumi Kamisawa, Atsushi Tanaka, Takahiro Nakazawa, Kensuke Kubota, Hajime Takikawa, Michiaki Unno, Atsushi Masamune, Shigeyuki Kawa, Seiji Nakamura …

Digestive and Liver Disease 53(10) 1308-1314 2021年3月査読有り
Protective Effect of Luminal Uric Acid Against Indomethacin-Induced Enteropathy: Role of Antioxidant Effect and Gut Microbiota

Akinori Wada, Masaaki Higashiyama, Chie Kurihara, Suguru Ito, Rina Tanemoto, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa …

Digestive Diseases and Sciences 67(1) 121-133 2021年2月11日査読有り
T1ρ magnetic resonance imaging value as a potential marker to assess the severity of liver fibrosis: A pilot study

Yohsuke Suyama, Kengo Tomita, Shigeyoshi Soga, Hiroshi Kuwamura, Wakana Murakami, Ryota Hokari, Hiroshi Shinmoto

European Journal of Radiology Open 8 100321-100321 2021年査読有り
Repeat Balloon-Occluded Retrograde Transvenous Obliteration for Recurrent Gastric Varices via the Left Inferior Phrenic Vein

Yohsuke Suyama, Kentaro Yamada, Masaki Tsuda, Kengo Tomita, Hiroshi Shinmoto

Journal of Vascular and Interventional Radiology 31(11) 1914-1916.e1 2020年11月査読有り
Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling.

Toshiaki Teratani, Kengo Tomita, Sachiko Toma-Fukai, Yutaro Nakamura, Toshimasa Itoh, Hikaru Shimizu, Yasunaga Shiraishi, Nao Sugihara, Masaaki Higashiyama, Takahiko Shimizu …

Free radical biology & medicine 156 45-56 2020年8月20日査読有り筆頭著者責任著者
Common Drug Pipelines for the Treatment of Diabetic Nephropathy and Hepatopathy: Can We Kill Two Birds with One Stone?

Yoshio Sumida, Masashi Yoneda, Hidenori Toyoda, Satoshi Yasuda, Toshifumi Tada, Hideki Hayashi, Yoichi Nishigaki, Yusuke Suzuki, Takafumi Naiki, Asahiro Morishita …

International journal of molecular sciences 21(14) 2020年7月13日査読有り
Associations among liver disease, serum lipid profile, body mass index, ketonuria, meal skipping, and the alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 genotypes in Japanese men with alcohol dependence.

Akira Yokoyama, Nobuhito Taniki, Nobuhiro Nakamoto, Kengo Tomita, Sachiko Hara, Takeshi Mizukami, Katsuya Maruyama, Tetsuji Yokoyama

Hepatology research : the official journal of the Japan Society of Hepatology 50(5) 565-577 2020年5月査読有り
Dietary emulsifier polysorbate-80-induced small-intestinal vulnerability to indomethacin-induced lesions via dysbiosis.

Hirotaka Furuhashi, Masaaki Higashiyama, Yoshikiyo Okada, Chie Kurihara, Akinori Wada, Kazuki Horiuchi, Yoshinori Hanawa, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba …

Journal of gastroenterology and hepatology 35(1) 110-117 2020年1月査読有り
Chitinase 3-like 1 deficiency ameliorates liver fibrosis by promoting hepatic macrophage apoptosis.

Masaaki Higashiyama, Kengo Tomita, Nao Sugihara, Hiroyuki Nakashima, Hirotaka Furuhashi, Makoto Nishikawa, Kenichi Inaba, Akinori Wada, Kazuki Horiuchi, Yoshinori Hanawa …

Hepatology research : the official journal of the Japan Society of Hepatology 49(11) 1316-1328 2019年11月査読有り責任著者
Lipoprotein Lipase Up-regulation in Hepatic Stellate Cells Exacerbates Liver Fibrosis in Nonalcoholic Steatohepatitis in Mice.

Toshiaki Teratani, Kengo Tomita, Hirotaka Furuhashi, Nao Sugihara, Masaaki Higashiyama, Makoto Nishikawa, Rie Irie, Takeshi Takajo, Akinori Wada, Kazuki Horiuchi …

Hepatology communications 3(8) 1098-1112 2019年8月査読有り筆頭著者責任著者
Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma.

Yoshinori Hanawa, Masaaki Higashiyama, Kazuki Horiuchi, Kana Ayaki, Suguru Ito, Akinori Mizoguchi, Shin Nishii, Akinori Wada, Kenichi Inaba, Nao Sugihara …

Internal medicine (Tokyo, Japan) 58(14) 2019-2023 2019年7月15日査読有り

もっとみる

MISC

THERAPEUTIC EFFICACY OF GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS IS CORRELATED WITH COLONIC MUCOSAL EXPRESSION OF TIGHT JUNCTION MOLECULES IN ULCERATIVE COLITIS

Chie Kurihara, Toshihide Ohmori, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, Suguru Ito …

GASTROENTEROLOGY 160(6) S504-S504 2021年5月
EFFICACY OF GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS TREATMENT IS CORRELATED WITH COLONIC MUCOSAL EXPRESSION OF TH17-ASOCIATED CYTOKINES IN ULCERATIVE COLITIS

Chie Kurihara, Toshihide Ohmori, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, Suguru Ito …

GASTROENTEROLOGY 158(6) S1046-S1046 2020年5月
ANTIOXIDANT EFFECT OF URIC ACID AMELIORATES NSAIDS INDUCED ENTEROPATHY AND CHANGES GUT MICROBIOTA

Akinori Wada, Masaaki Higashiyama, Suguru Ito, Rina Tanemoto, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi …

GASTROENTEROLOGY 158(6) S504-S504 2020年5月
HIGHER TNF alpha AND MIP-1 beta EXPRESSION IN PRETREATMENT COLONIC MUCOSA HAVE POTENTIAL TO PREDICT OF ACHIEVING MUCOSAL HEALING BY GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS THERAPY IN ULCERATIVE COLITIS PATIENTS

Chie Kurihara, Toshihide Ohmori, Hirotaka Furuhashi, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi …

GASTROENTEROLOGY 156(6) S1146-S1146 2019年5月
HYPERURICEMIA AMELIORATES INTESTINAL INFLAMMATION ALONG WITH ALTERED GUT MICROBIOTA

Akinori Wada, Masaaki Higashiyama, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Hirotaka Furuhashi, Naoki Shibuya …

GASTROENTEROLOGY 156(6) S707-S707 2019年5月
DIETARY EMULSIFIER POLYSORBATE-80 INCREASES THE GENUS PROTEUS AND CAUSES INTESTINAL INFLAMMATION ON INDOMETHACIN-INDUCED INTESTINAL LESIONS

Hirotaka Furuhashi, Masaaki Higashiyama, Yoshikiyo Okada, Takeshi Takajo, Koji Maruta, Kazuhiko Shirakabe, Chie Kurihara, Chikako Watanabe, Shunsuke Komoto, Kengo Tomita …

GASTROENTEROLOGY 152(5) S814-S814 2017年4月
CARAMEL FOOD COLORANT 2-ACCETYL-4-TETRAHYDROXYBUTYL IMIDAZOLE (THI) AMELIORATES DEXTRAN SULFATE SODIUM (DSS)-INDUCED COLITIS VIA SUPPRESSION OF SPHINGOSINE-1-PHOSPHATE (S1P) LYASE

Kazuhiko Shirakabe, Masaaki Higashiyama, Hirotaka Furuhashi, Takeshi Takajo, Koji Maruta, Chie Kurihara, Yoshikiyo Okada, Chikako Watanabe, Shunsuke Komoto, Kengo Tomita …

GASTROENTEROLOGY 152(5) S572-S572 2017年4月
PSYCHOLOGICAL STRESS INDUCES DIFFERENT PATTERNS OF THE GUT MICROBIOTA ACCORDING WITH CHARACTERISTIC CHANGES IN BEHAVIOR AND VISCERAL PERCEPTION IN AN EXPERIMENTAL RAT MODEL

Takeshi Takajo, Kunio Shimizu, Shingo Enomoto, Masaaki Tanichi, Hiroyuki Toda, Kengo Tomita, Yoshikiyo Okada, Chie Kurihara, Kazuhiko Shirakabe, Hirotaka Furuhashi …

GASTROENTEROLOGY 152(5) S818-S819 2017年4月
Free cholesterol accumulation in liver sinusoidal endothelial cells exacerbates acetaminophen hepatotoxicity in mice

T. Teratani, K. Tomita, T. Suzuki, H. Furuhashi, R. Irie, S. Hida, Y. Okada, C. Kurihara, H. Ebinuma, N. Nakamoto …

JOURNAL OF HEPATOLOGY 66(1) S398-S399 2017年
Anti-Inflammatory Effect of Novel Probiotic Yeasts Isolated From Japanese "Miso" on DSS-Induced Colitis

Yoshikiyo Okada, Yoshikazu Tsuzuki, Yuichi Yasutake, Koji Maruta, Takeshi Takajo, Hirotaka Furuhashi, Masaaki Higashiyama, Kenichi Yoshikawa, Kengo Tomita, Chikako Watanabe …

GASTROENTEROLOGY 150(4) S1008-S1008 2016年4月
Dietary Emulsifier Polysorbate-80 Exacerbates Indomethacin-Induced Small Intestinal Lesions in Mice

Hirotaka Furuhashi, Masaaki Higashiyama, Takeshi Takajo, Koji Maruta, Yuichi Yasutake, Kenichi Yoshikawa, Chie Kurihara, Yoshikiyo Okada, Chikako Watanabe, Shunsuke Komoto …

GASTROENTEROLOGY 150(4) S200-S200 2016年4月
Nicotine Ameliorates Colonic Inflammation via Inhibition of Leukocyte Interaction to Colonic Microvessels and Down-Regulation of MAdCAM-1

Koji Maruta, Chie Kurihara, Hirotaka Furuhashi, Takeshi Takajo, Yuichi Yasutake, Yoshikiyo Okada, Kenichi Yoshikawa, Masaaki Higashiyama, Chikako Watanabe, Shunsuke Komoto …

GASTROENTEROLOGY 150(4) S965-S965 2016年4月
Suppressive effect of nicotine on expression of MAdCAM-1 in colitis

Koji Maruta, Chie Kurihara, Hirotaka Furuhashi, Takeshi Takajo, Yuichi Yasutake, Yoshikiyo Okada, Kenichi Yoshikawa, Masaaki Higashiyama, Chikako Watanabe, Shunsuke Komoto …

FASEB JOURNAL 30 2016年4月
Uric Acid Inhibits Lipid Peroxidation and Protects Small Intestinal Injury Induced by Indomethacin

Yuichi Yasutake, Hirotaka Furuhashi, Takeshi Takajo, Koji Maruta, Chie Kurihara, Yoshikiyo Okada, Kenichi Yoshikawa, Masaaki Higashiyama, Chikako Watanabe, Shunsuke Komoto …

GASTROENTEROLOGY 150(4) S896-S897 2016年4月
Psychological Stress Exacerbates Indomethacin-Induced Small Intestinal Injury Possibly via Changes in Intestinal Microbiota

Kenichi Yoshikawa, Chie Kurihara, Hirotaka Furuhashi, Takeshi Takajo, Koji Maruta, Yuichi Yasutake, Yoshikiyo Okada, Masaaki Higashiyama, Chikako Watanabe, Shunsuke Komoto …

GASTROENTEROLOGY 150(4) S541-S542 2016年4月
Stress Induced Different Psychological Disorders Showed Characteristic Patterns of Gut Microbiota Leading to Bowel Movement Disturbance in Rats

Takeshi Takajo, Yoshikiyo Okada, Chie Kurihara, Kenichi Yoshikawa, Hirotaka Furuhashi, Koji Maruta, Shingo Enomoto, Masaaki Tanichi, Yuichi Yasutake, Masaaki Higashiyama …

GASTROENTEROLOGY 150(4) S525-S526 2016年4月
Investigation of Mismatch Cases Between Magnetic Resonance Enterocolonography and Endoscopy in Intestinal Lesion of Patients with Crohn's Disease

Kenichi Yoshikawa, Hirokazu Sato, Takeshi Takajo, Koji Maruta, Yuichi Yasutake, Kazuyuki Narimatsu, Chie Kurihara, Yoshikiyo Okada, Masaaki Higashiyama, Chikako Watanabe …

INFLAMMATORY BOWEL DISEASES 22 S46-S46 2016年3月
Nicotine Significantly Affects the Expression of Vascular Endothelial Adhesion Molecules and Ameliorates DSS Induced Colitis

Koji Maruta, Chie Kurihara, Hideaki Hozumi, Takeshi Takajo, Yuichi Yasutake, Hirokazu Sato, Kazuyuki Narimatsu, Yoshikiyo Okada, Kenichi Yoshikawa, Chikako Watanabe …

GASTROENTEROLOGY 148(4) S686-S686 2015年4月
Clinical Response to Medical Treatment and Prognosis of Cronkhite-Canada Syndrome - A Japanese Nationwide Survey

Chikako Watanabe, Kazuyuki Narimatsu, Hirokazu Sato, Shingo Usui, Shunsuke Komoto, Kengo Tomita, Ryota Hokari, Soichiro Miura

GASTROENTEROLOGY 146(5) S795-S795 2014年5月
Possible Protective Role of Lymphangiogenesis in the Inflamed Colonic Mucosa of Inflammatory Bowel Diseases

Hirokazu Sato, Ryota Hokari, Koji Maruta, Yuichi Yasutake, Kazuyuki Narimatsu, Chie Kurihara, Yoshikiyo Okada, Chikako Watanabe, Shunsuke Komoto, Kengo Tomita …

GASTROENTEROLOGY 146(5) S645-S645 2014年5月

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