2012年2月
Ultrafast 1D MR thermometry using phase or frequency mapping
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
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- 巻
- 25
- 号
- 1
- 開始ページ
- 5
- 終了ページ
- 14
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1007/s10334-011-0272-9
- 出版者・発行元
- SPRINGER
Object To develop an ultrafast MRI-based temperature monitoring method for application during rapid ultrasound exposures in moving organs.
Materials and methods A slice selective 90 degrees - 180 degrees pair of RF pulses was used to solicit an echo from a column, which was then sampled with a train of gradient echoes. In a gel phantom, phase changes of each echo were compared to standard gradient-echo thermometry, and temperature monitoring was tested during focused ultrasound sonications. Signal-to-noise ratio (SNR) performance was evaluated in vivo in a rabbit brain, and feasibility was tested in a human heart.
Results The correlation between each echo in the acquisition and MRI-based temperature measurements was good (R = 0.98 +/- 0.03). A temperature sampling rate of 19 Hz was achieved at 3T in the gel phantom. It was possible to acquire the water frequency in the beating heart muscle with 5-Hz sampling rate during a breath hold.
Conclusion Ultrafast thermometry via phase or frequency monitoring along single columns was demonstrated. With a temporal resolution around 50 ms, it may be possible to monitor focal heating produced by short ultrasound pulses.
Materials and methods A slice selective 90 degrees - 180 degrees pair of RF pulses was used to solicit an echo from a column, which was then sampled with a train of gradient echoes. In a gel phantom, phase changes of each echo were compared to standard gradient-echo thermometry, and temperature monitoring was tested during focused ultrasound sonications. Signal-to-noise ratio (SNR) performance was evaluated in vivo in a rabbit brain, and feasibility was tested in a human heart.
Results The correlation between each echo in the acquisition and MRI-based temperature measurements was good (R = 0.98 +/- 0.03). A temperature sampling rate of 19 Hz was achieved at 3T in the gel phantom. It was possible to acquire the water frequency in the beating heart muscle with 5-Hz sampling rate during a breath hold.
Conclusion Ultrafast thermometry via phase or frequency monitoring along single columns was demonstrated. With a temporal resolution around 50 ms, it may be possible to monitor focal heating produced by short ultrasound pulses.
- リンク情報
- ID情報
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- DOI : 10.1007/s10334-011-0272-9
- ISSN : 0968-5243
- Web of Science ID : WOS:000302246900002