2008年2月
Transcriptional regulation of genes on the non-syntenic blocks of Aspergillus oryzae and its functional relationship to solid-state cultivation
FUNGAL GENETICS AND BIOLOGY
- 巻
- 45
- 号
- 2
- 開始ページ
- 139
- 終了ページ
- 151
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.fgb.2007.09.005
- 出版者・発行元
- ACADEMIC PRESS INC ELSEVIER SCIENCE
Transcriptome analysis revealed close relationship between solid-state cultivation and the transcriptional regulation of the genes on the non-syntenic blocks (NSBs), which were characterized by the comparison of Aspergillus oryzae genome with those of Aspergillus fumigatus and Aspergillus nidulans. Average expression ratio of the genes on NSBs in solid-state cultivation was significantly higher than that on the syntenic blocks (SBs). Of the induced genes, the genes relating to metabolism, which are highly enriched on NSBs, most contributed to the NSB-specific induction. The analysis using the SB- and NSB-genes that had sequence similarity between the two blocks significantly decreased the difference of average expression ratios between the two blocks. In spite of remarkably high averaged expression ratio of the NSB genes encoding extracellular enzymes, no induction of PKS and NRPS genes on NSBs were observed in solid-state cultivations. These results strongly suggest that the genes on NSBs play an important role on solid-state fermentation. (c) 2007 Elsevier Inc. All rights reserved.
- リンク情報
-
- DOI
- https://doi.org/10.1016/j.fgb.2007.09.005
- CiNii Articles
- http://ci.nii.ac.jp/naid/80019346889
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/17967552
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000253045700006&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1016/j.fgb.2007.09.005
- ISSN : 1087-1845
- CiNii Articles ID : 80019346889
- PubMed ID : 17967552
- Web of Science ID : WOS:000253045700006