2004年9月
Co-localization of Trax and Mea2 in Golgi complex of pachytene spermatocytes in the mouse
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
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- 巻
- 52
- 号
- 9
- 開始ページ
- 1245
- 終了ページ
- 1248
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1369/jhc.4B6304.2004
- 出版者・発行元
- HISTOCHEMICAL SOC INC
A golgin family protein, Mea2, is expressed at enhanced level in pachytene spermatocytes and is indispensable for mouse spermatogenesis. Because Trax was shown to interact with Mea2 in yeast two-hybrid, we investigated the localization of Trax in pachytene spermatocytes with immunofluorescent staining. Trax was found to accumulate in the Golgi complex of mid-late pachytene spermatocytes and intermingled with granular Mea2 signal in the central region. In a subline of the Mea2 mutant mouse, a truncated form of Mea2 devoid of the N-terminal region, DeltaMea2, was expressed. It localized to the rim of Golgi complex and thus occupied a region separate from that of Trax.
- リンク情報
- ID情報
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- DOI : 10.1369/jhc.4B6304.2004
- ISSN : 0022-1554
- Web of Science ID : WOS:000223467600014