鶴見達也 (Tatsuya Tsurumi) - マイポータル

基本情報

所属: 愛知県がんセンター研究所腫瘍ウイルス学部部長

学位: 医学博士(名古屋大学)

J-GLOBAL ID: 200901055692558267
researchmap会員ID: 0000201851

外部リンク: http://www.pref.aichi.jp/cancer-center/400/420/421/421-06.html

研究キーワード

研究分野

ライフサイエンス / ウイルス学 /

学歴

委員歴

2002年 - 2006年

日本癌学会, 評議員
2000年 - 2003年

日本ウイルス学会, 理事

受賞

1994年

日本ウイルス学会杉浦奨励賞

MISC

Enhanced cytotoxicity with a novel system combining the paclitaxel-2 '-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus

Daisuke Ishida, Akihiro Nawa, Tadatoshi Tanino, Fumi Goshima, Chen Hong Luo, Masahiro Iwaki, Hiroaki Kajiyama, Kiyosumi Shibata, Eiko Yamamoto, Kazuhiko Ino …

CANCER LETTERS 288(1) 17-27 2010年2月
Transient increases in p53-responsible gene expression at early stages of Epstein-Barr virus productive replication.

Sato Y, Shirata N, Murata T, Nakasu S, Kudoh A, Iwahori S, Nakayama S, Chiba S, Isomura H, Kanda T …

Cell Cycle. 9(4) 807-14 2010年
Crystal Structure of Epstein-Barr Virus DNA Polymerase Processivity Factor BMRF1

Kazutaka Murayama, Sanae Nakayama, Miyuki Kato-Murayama, Ryogo Akasaka, Naomi Ohbayashi, Yuki Kamewari-Hayami, Takaho Terada, Mikako Shirouzu, Tatsuya Tsurumi, Shigeyuki Yokoyama

JOURNAL OF BIOLOGICAL CHEMISTRY 284(51) 35896-35905 2009年12月
Epstein-Barr Virus Polymerase Processivity Factor Enhances BALF2 Promoter Transcription as a Coactivator for the BZLF1 Immediate-Early Protein

Sanae Nakayama, Takayuki Murata, Kazutaka Murayama, Yoshihiro Yasui, Yoshitaka Sato, Ayumi Kudoh, Satoko Iwahori, Hiroki Isomura, Teru Kanda, Tatsuya Tsurumi

JOURNAL OF BIOLOGICAL CHEMISTRY 284(32) 21557-21568 2009年8月
Degradation of Phosphorylated p53 by Viral Protein-ECS E3 Ligase Complex

Yoshitaka Sato, Takumi Kamura, Noriko Shirata, Takayuki Murata, Ayumi Kudoh, Satoko Iwahori, Sanae Nakayama, Hiroki Isomura, Yukihiro Nishiyama, Tatsuya Tsurumi

PLOS PATHOGENS 5(7) e1000530 2009年7月
Phosphorylation of p27(Kip1) by Epstein-Barr Virus Protein Kinase Induces Its Degradation through SCFSkp2 Ubiquitin Ligase Actions during Viral Lytic Replication

Satoko Iwahori, Takayuki Murata, Ayumi Kudoh, Yoshitaka Sato, Sanae Nakayama, Hiroki Isomura, Teru Kanda, Tatsuya Tsurumi

JOURNAL OF BIOLOGICAL CHEMISTRY 284(28) 18923-18931 2009年7月
Homologous Recombinational Repair Factors Are Recruited and Loaded onto the Viral DNA Genome in Epstein-Barr Virus Replication Compartments

Ayumi Kudoh, Satoko Iwahori, Yoshitaka Sato, Sanae Nakayama, Hiroki Isomura, Takayuki Murata, Tatsuya Tsurumi

JOURNAL OF VIROLOGY 83(13) 6641-6651 2009年7月
Efficient production of infectious viruses requires enzymatic activity of Epstein-Barr virus protein kinase

Takayuki Murata, Hiroki Isomura, Yoriko Yamashita, Shigenori Toyama, Yoshitaka Sato, Sanae Nakayama, Ayumi Kudoh, Satoko Iwahori, Teru Kanda, Tatsuya Tsurumi

VIROLOGY 389(1-2) 75-81 2009年6月
Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription

Yoshitaka Sato, Noriko Shirata, Ayumi Kudoh, Satoko Iwahori, Sanae Nakayama, Takayuki Murata, Hiroki Isomura, Yukihiro Nishiyama, Tatsuya Tsurumi

VIROLOGY 388(1) 204-211 2009年5月
TORC2, a Coactivator of cAMP-response Element-binding Protein, Promotes Epstein-Barr Virus Reactivation from Latency through Interaction with Viral BZLF1 Protein

Takayuki Murata, Yoshitaka Sato, Sanae Nakayama, Ayumi Kudoh, Satoko Iwahori, Hiroki Isomura, Masako Tajima, Takayuki Hishiki, Takayuki Ohshima, Makoto Hijikata …

JOURNAL OF BIOLOGICAL CHEMISTRY 284(12) 8033-8041 2009年3月
TORC 2, a coactivator of CREB, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 protein.

Murata T, Sato Y, Nakayama S, Kudoh A, Iwahori S, Isomura H, Tajima M, Hishiki T, Ohshima T, Hijikata M …

J Biol Chem. 2009年
Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites

Satoko Iwahori, Yoshihiro Yasui, Ayumi Kudoh, Yoshitaka Sato, Sanae Nakayama, Takayuki Murata, Hiroki Isomura, Tatsuya Tsurumi

CELLULAR SIGNALLING 20(10) 1795-1803 2008年10月
Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts

Hiroki Isomura, Mark F. Stinski, Ayumi Kudoh, Takayuki Murata, Sanae Nakayama, Yoshitaka Sato, Satoko Iwahori, Tatsuya Tsurumi

JOURNAL OF VIROLOGY 82(4) 1638-1646 2008年2月
A cis element between the TATA box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication

Hiroki Isomura, Mark F. Stinski, Ayumi Kudoh, Sanae Nakayama, Takayuki Murata, Yoshitaka Sato, Satoko Iwahori, Tatsuya Tsurumi

JOURNAL OF VIROLOGY 82(2) 849-858 2008年1月
Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein

Satoko Iwahori, Noriko Shirata, Yasushi Kawaguchi, Sandra K. Weller, Yoshitaka Sato, Ayumi Kudoh, Sanae Nakayama, Hiroki Isomura, Tatsuya Tsurumi

JOURNAL OF VIROLOGY 81(18) 9653-9664 2007年9月
The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delaye early and late viral gene products but not on viral DNA synthesis

Hiroki Isomura, Mark F. Stinski, Ayumi Kudoh, Sanae Nakayama, Satoko Iwahori, Yoshitaka Sato, Tatsuya Tsurumi

JOURNAL OF VIROLOGY 81(12) 6197-6206 2007年6月
The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delaye early and late viral gene products but not on viral DNA synthesis

Hiroki Isomura, Mark F. Stinski, Ayumi Kudoh, Sanae Nakayama, Satoko Iwahori, Yoshitaka Sato, Tatsuya Tsurumi

JOURNAL OF VIROLOGY 81(12) 6197-6206 2007年6月
Paclitaxel-2 '-ethylcarbonate prodrug can circumvent P-glycoprotein-mediated cellular efflux to increase drug cytotoxicity

Tadatoshi Tanino, Akihiro Nawa, Eisaku Kondo, Fumitaka Kikkawa, Tohru Daikoku, Tatsuya Tsurumi, ChenHong Luo, Yukihiro Nishiyama, Yuki Takayanagi, Katuhiko Nishimori …

PHARMACEUTICAL RESEARCH 24(3) 555-565 2007年3月
Replication of DNA viruses and host DNA damage responses

Tsurumi T, Kudoh A

Tanpakushitsu Kakusan Koso. 52(10) 1155-60 2007年
Establishment of a novel foreign gene delivery system combining an HSV amplicon with an attenuated replication-competent virus, HSV-1HF10

Lumin Zhang, Tohru Daikoku, Koichiro Ohtake, Junpei Ohtsuka, Akihiro Nawa, Ayumi Kudoh, Satoko Iwahori, Hiroki Isomura, Yukihiro Nishiyama, Tatsuya Tsurumi

JOURNAL OF VIROLOGICAL METHODS 137(2) 177-183 2006年11月

もっとみる

書籍等出版物

The CD8^＋T response to Epstein-Barr virs.

Current Topics in Virology 2002年
Molecular basis for Epstein-Barr virus CNA Replication

Current Topics in Virology 2002年
Molecular basis for Epstein-Barr virus CNA Replication

Current Topics in virology
The CD8^＋T response to Epstein-Barr virs.

Current Topics in Virology

所属学協会

共同研究・競争的資金等の研究課題

Epstein-Barrウイルスの増殖機構の解析と宿主機能との相互作用
Epstein-Barrウイルスのゲノム複製と宿主DNA損傷応答の分子機構

科学研究費補助金
DNA replication of Epstein-Barr virus and host DNA damage response

Grant-in-Aid for Scientific Research

鶴見達也

基本情報

研究キーワード

研究分野

学歴

委員歴

受賞

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

産業財産権

メニュー