MAEHAMA Tomohiko

J-GLOBAL         Last updated: Jun 27, 2018 at 02:59
 
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Name
MAEHAMA Tomohiko
Affiliation
Kobe University
Section
Graduate School of Medicine Faculty of Medical Sciences
Job title
Associate Professor

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
Kobe University Graduate School of Medicine
 

Published Papers

 
Nishio M, Maehama T, Goto H, Nakatani K, Kato W, Omori H, Miyachi Y, Togashi H, Shimono Y, Suzuki A
Genes to cells : devoted to molecular & cellular mechanisms   22(1) 31   Jan 2017   [Refereed]
Nakatani K, Maehama T, Nishio M, Goto H, Kato W, Omori H, Miyachi Y, Togashi H, Shimono Y, Suzuki A
Journal of biochemistry      Dec 2016   [Refereed]
Maehama T, Kawahara K, Nishio M, Suzuki A, Hanada K
The Journal of biological chemistry   289(30) 20802-20812   Jul 2014   [Refereed]
Maehama T, Fukasawa M, Date T, Wakita T, Hanada K
Biochemical and biophysical research communications   440(1) 150-156   Oct 2013   [Refereed]
Nishio M, Otsubo K, Maehama T, Mimori K, Suzuki A
Cancer science   104(10) 1271-1277   Jul 2013   [Refereed]
Kukimoto I, Maehama T, Sekizuka T, Ogasawara Y, Kondo K, Kusumoto-Matsuo R, Mori S, Ishii Y, Takeuchi T, Yamaji T, Takeuchi F, Hanada K, Kuroda M
PloS one   8(11)    2013   [Refereed]
Suzuki A, Kogo R, Kawahara K, Sasaki M, Nishio M, Maehama T, Sasaki T, Mimori K, Mori M
Cancer science   103(4) 632-637   Apr 2012   [Refereed]
Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A
Nature medicine   17(8) 944-951   Jul 2011   [Refereed]
Tanaka M, Hara H, Nishina H, Hanada K, Hagiwara K, Maehama T
Biochemical and biophysical research communications   397(3) 505-508   Jul 2010   [Refereed]
Malchinkhuu E, Sato K, Maehama T, Ishiuchi S, Yoshimoto Y, Mogi C, Kimura T, Kurose H, Tomura H, Okajima F
Molecular biology of the cell   20(24) 5156-5165   Dec 2009   [Refereed]
Maehama T, Tanaka M, Nishina H, Murakami M, Kanaho Y, Hanada K
The Journal of biological chemistry   283(50) 35053-35059   Dec 2008   [Refereed]
Malchinkhuu E, Sato K, Maehama T, Mogi C, Tomura H, Ishiuchi S, Yoshimoto Y, Kurose H, Okajima F
Biochemical and biophysical research communications   366(4) 963-968   Feb 2008   [Refereed]
Maehama T
Biological & pharmaceutical bulletin   30(9) 1624-1627   Sep 2007   [Refereed]
Okahara F, Itoh K, Nakagawara A, Murakami M, Kanaho Y, Maehama T
Molecular biology of the cell   17(11) 4888-4895   Nov 2006   [Refereed]
Nigorikawa K, Yoshikawa K, Sasaki T, Iida E, Tsukamoto M, Murakami H, Maehama T, Hazeki K, Hazeki O
Molecular pharmacology   70(3) 1143-1149   Sep 2006   [Refereed]
Suzuki T, Kanai Y, Hara T, Sasaki J, Sasaki T, Kohara M, Maehama T, Taya C, Shitara H, Yonekawa H, Frohman MA, Yokozeki T, Kanaho Y
Molecular and cellular biology   26(16) 6149-6156   Aug 2006   [Refereed]
[Regulation of the lipid phosphatase PTEN].
Maehama T
Seikagaku. The Journal of Japanese Biochemical Society   78 133-137   Feb 2006   [Refereed]
Miyazaki H, Yamazaki M, Watanabe H, Maehama T, Yokozeki T, Kanaho Y
FEBS letters   579(30) 6834-6838   Dec 2005   [Refereed]
Sasaki J, Sasaki T, Yamazaki M, Matsuoka K, Taya C, Shitara H, Takasuga S, Nishio M, Mizuno K, Wada T, Miyazaki H, Watanabe H, Iizuka R, Kubo S, Murata S, Chiba T, Maehama T, Hamada K, Kishimoto H, Frohman MA, Tanaka K, Penninger JM, Yonekawa H, Suzuki A, Kanaho Y
The Journal of experimental medicine   201(6) 859-870   Mar 2005   [Refereed]
Okahara F, Itoh K, Ebihara M, Kobayashi M, Maruyama H, Kanaho Y, Maehama T
Analytical biochemistry   336(1) 138-140   Jan 2005   [Refereed]

Misc

 
Nishio Miki, , GotoH, NakataniK, KatoW, OmoriH, MiyachiY, Togashi Hideru, Shimono Yohei, Suzuki Akira
Genes Cells   22(1) 31   Jan 2017   [Refereed]
Targeting the Hippo signalling pathway for cancer treatment
NakataniK, , Nishio Miki, GotoH, KatoW, OmoriH, MiyachiY, Togashi Hideru, Shimono Yohei, Suzuki Akira
J Biochem      Dec 2016   [Refereed]
Maehama T., Dixon J.E., Taylor G.S.
Annu. Rev. Biochem.   70 247-279   2001
LEE J‐O, YANG H, GEORGESCU M‐M, DI CRISTOFANO A, MAEHAMA T, SHI Y, DIXON J E, PANDOLFI P, PAVLETICH N P
Cell   99(3) 323-334   1999

Conference Activities & Talks

 
Regulation of nucleolar stress response and tumorigenesis by PICT1
Maehama Tomohiko, Nishio Miki, Yousuke Miyachi, Suzuki Akira
第2回 神大・ワシントン大・オスロ大 国際合同シンポジウム   Mar 2018   
Hippoシグナル経路による細胞増殖変化と細胞間コミュニケーション
Nishio Miki, Maehama Tomohiko, , Suzuki Akira
新学術領域「幹細胞老化と疾患」「細胞競合」総括班主催「若手の会」   Feb 2018   
唾液腺におけるMob1a/1bの機能解析
宮地 洋佑, Nishio Miki, Maehama Tomohiko, Suzuki Akira
新学術領域「幹細胞老化と疾患」「細胞競合」総括班主催「若手の会」   Feb 2018   
がん制御因子PICT1の安定化機構 [Invited]
Maehama Tomohiko, 宮地 洋佑, Nishio Miki, Suzuki Akira
2017年度生命科学系学会合同年次大会ConBio   Dec 2017   
Role of MOB1A/1B in salivary gland [Invited]
Yosuke Miyachi, Nishio Miki, Hiroki Goto, Maehama Tomohiko, Suzuki Akira
EMBO workshop ‘The Hippo pathway across species and disciplines’   Oct 2017   

Association Memberships

 
 

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(挑戦的萌芽研究)
Project Year: 2011 - 2012    Investigator(s): Tomohiko MAEHAMA
Small GTPases play pivotal roles in diverse intracellular signal transduction pathways. In this study, we applied RIRAG method to several small GTPases and found novel signaling pathway that ERK activation was induced by CDC42. The RIRAG method, i...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2007 - 2009    Investigator(s): Tomohiko MAEHAMA
Cellular lipids function as building blocks of biomembranes and signaling molecules thereby being fundamental components for all cells. In this study, we analyzed the function of cellular lipids for infection cycle of hepatitis C virus and infecti...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2004 - 2005    Investigator(s): Yasunori KANAHO
We have investigated activation mechanisms and physiological functions of phosphatidylinositol 4-phosphate 5-kinase (PIP5K) which produces the pleiotropic phospholipid, phosphatidylinositol 4,5-bisphosphate, in neuronal cells. So far, we have obta...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2002 - 2003    Investigator(s): Yasunori KANAHO
Mammalian phospholipase D (PLD) is a novel signal transducing enzyme, which is believed to play roles in a wide variety of cell functions. Two mammalian PLD isozymes, PLD1 and PLD2,have been identified. Although activation mechanisms and physiolog...
Study of Lipid Second Messengers