坂口和成 (Kazushige Sakaguchi) - マイポータル - researchmap

基本情報

所属: 和歌山県立医科大学付置先端医学研究所分子医学研究部教授

学位: 医学博士

J-GLOBAL ID: 200901077504098223
researchmap会員ID: 0000202105

研究キーワード

9

経歴

29

1997年 - 現在

和歌山県立医科大学先端医学研究所分子医学研究部教授
1996年 - 1997年

: Visiting Professor, Dept. of Biomedical
1996年 - 1997年

Visiting Professor (Sabbatical) at the Department of Biomedical
1997年

, Dec- Professor and Chairman, Department of Molecular Medicine, Wakayama
1993年 - 1996年

: Visiting Scientist, Bone Research Branch,
1993年 - 1996年

Visiting Scientist, Bone Research Branch, NIDR, National Institutes
1989年 - 1993年

: Visiting Associate, Metabolic Diseases Branch,
1989年 - 1993年

Visiting Associate, Metabolic Diseases Branch (Chief: Gerald D.
1986年 - 1989年

: Visiting Fellow, Metabolic Diseases Branch,
1986年 - 1989年

Visiting Fellow, Metabolic Diseases Branch (Chief: Gerald D.
1984年 - 1985年

: 北兵庫内科整形外科センター内科医長
1984年 - 1985年

Chief, Department of Internal Medicine, North Hyogo Medical and
1985年

: 神戸大学第三内科助手
1985年

Assistant Professor, Third Division, Department of Medicine, Kobe
1980年 - 1984年

: 神戸大学医学部大学院生
1980年 - 1984年

Graduate School of Medical Sciences, Kobe University.
1981年

Research fellowship at the Mathilda and Terence Kennedy Institute of Rheumatology, London, under the direction of Dr. Joseph Chayen.
1977年 - 1980年

: 国家公務員共済組合連合会虎の門病院内科レジデント
1977年 - 1980年

Residency in the Department of Internal Medicine, Toranomon Hospital,
Engineering, Cleveland Clinic Foundation

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学歴

4

受賞

3

MISC

98

Identification of a novel activated form of the keratinocyte growth factor receptor by expression cloning from parathyroid adenoma tissue

Kazushige Sakaguchi, Matthew V. Lorenzi, Hiroshi Matsushita, Toru Miki

Oncogene 18(40) 5497-5505 1999年9月30日
FRAG1, a gene that potently activates fibroblast growth factor receptor by C-terminal fusion through chromosomal rearrangement

Matthew V. Lorenzi, Yoshihiro Horii, Ryuya Yamanaka, Kazushige Sakaguchi, Toru Miki

Proceedings of the National Academy of Sciences of the United States of America 93(17) 8956-8961 1996年8月20日
Heparan sulfate proteoglycan and FGF receptor.

Allergology 2: 1-6, 1996
Regulation of parathyroid cells by an endothelin autocrine system. in Endothelins in Endocrinology: New Advances.

Rome: Ares-Serono Symposia Publications, pp. 181-185, 1995
Autocrine and paracrine functions of parathyroid tissue. in The Parathyroids.

New York: Raven Press, pp. 93-105, 1994
Genetic abnormality of parathyroid tumors.

Taisha (Japan), 28: 17-21, 1991
Parathyroid tumors in familial multiple endocrine neoplasia type I: the role of direct acting oncogenes and tumor suppressor genes. In: Calcium regulation and bone metabolism.

Elsevier Science Publishers B.V.,Amsterdam, vol 10: pp 113-117, 1990
Pathophysiology of familial multiple endocrine neoplasia type I, In: Calcium regulation and bone metabolism.

Elsevier Science Publishers B.V., Amsterdam, vol 10: pp 107-112, 1990
Multiple endocrine neoplasia type I: role of a circulating growth factor in parathyroid cell hyperplasia. In: Clinical disorders of bone and mineral metabolism.

New York: Mary Ann Liebert, pp 323-328, 1989
Parathyroid cell mitogen in familial multiple endocrine neoplasia type I. In: Progress in endocrinology 1988.

Elsevier Science Publishers B.V., Amsterdam, pp 1349-1356, 1988
Vitamin D₃ regulation of growth and differentiation of bovine parathyroid cells in cultures. In: Calcium Regulation and Bone Metabolism: Basic and Clinical Aspects.

Elsevier Science Publishers B.V., Amsterdam, vol 9: pp 238-242, 1987
Pathophysiology of parathyroid gland dysfunction in familial multiple endocrine neoplasia type I. In: Calcium Regulation and Bone Metabolism: Basic and Clinical Aspects.

Elsevier Science Publishers B.V., Amsterdam, vol 9: pp 43-48, 1987
Is it necessary to supplement vitamin D in the cytochemical bioassay of parathyroid hormone? In: Endocrine control of bone and calcium metabolism vol. 8B:40-41, 1984
Urinary phosphate and cyclic adenosine monophosphate response to intravenous administration of synthetic human parathyroid hormone-(1-34) in idiopathic hypoparathyroidism, pseudohypoparathyroidism, pseudopseudohypoparathyroidism and normal subjects.

Folia Endocrinologica Japonica 60: 159-170, 1984
The acidic domain and first immunoglobulin-like loop of FGF receptor-2 modulate downstream signaling through glycosaminoglycan modification.

Mol. Cell. Biol. 19: 6754-6764, 1999
Synthetic parathyroid hormone fragments shortened at amino terminus stimulate glucose-6-phosphate dehydrogenase activity in the renal distal tubule.

J. Bone Miner. Res. 2:83-90, 1987
Subclones of a rat parathyroid cell line (PT-r): regulation of growth and production of parathyroid hormone-related peptide (PTHRP).

J. Bone Miner. Res. 5:863-869, 1990
Stimulation test for parathyroid hormone secretion by EDTA.

Japanese Journal of Bone Metabolism 14:326-331, 1981
Pseudohypoparathyroidism.

Medicine (Japan) 19: 1208-1210, 1982
Natriuretic peptide receptors regulate endothelin synthesis and release from parathyroid cells.

Proc. Natl. Acad. Sci. U.S.A. 88:6496-6500, 1991

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所属学協会

13

共同研究・競争的資金等の研究課題

2

産業財産権

1

Bovine Parathyroid Endothelial Cell Line