Minoru Sugiura

Profile Information

Affiliation: Doshisha Women's College of Liberal Arts

Degree: Doctor of Pharmaceutical Science(The University of Tokyo)

J-GLOBAL ID: 200901080815236876
researchmap Member ID: 0000202934

External link: https://www.dwc.doshisha.ac.jp/faculty_dep_info/life/nutrition_science/food_science

β－クリプトキサンチンをはじめとする食品中の機能性成分の健康維持・増進作用や糖尿病等の生活習慣病に対する予防改善効果について細胞レベルからヒトレベルまで広範囲に渡って検証を進めています。またこれらの研究成果を活用した機能性表示食品の開発も進めています。

Research Interests

Research Areas

Research History

Leader, Postharvest Physiology and Health Benefits Unit, National Agriculture and Food Research Organization Institute of Fruit Tree and Tea Science,NARO, Division of Citrus Research, Postharvest Physiology and Health Benefits Unit

Education

Papers

β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice.

Wanpitak Pongkan, Osamu Takatori, Yinhua Ni, Liang Xu, Naoto Nagata, Siriporn C Chattipakorn, Soichiro Usui, Shuichi Kaneko, Masayuki Takamura, Minoru Sugiura …

Molecular nutrition & food research, 61(10), Oct, 2017 Peer-reviewed
Amelioration of the Development of Osteoarthritis by Daily Intake of beta-Cryptoxanthin

Gyujin Park, Tetsuhiro Horie, Kazuya Fukasawa, Kakeru Ozaki, Yuki Onishi, Takashi Kanayama, Takashi Iezaki, Katsuyuki Kaneda, Minoru Sugiura, Eiichi Hinoi

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40(7) 1116-1120, Jul, 2017 Peer-reviewed
Effect of β-cryptoxanthin–rich Satsuma mandarin juice supplementation on pulse wave velocity: A randomized controlled trial

M. Nakamura, M. Sugiura, Y. Shibata, T. Ojima

Journal of Nutrition and Intermediary Metabolism, 8 8-13, Jun 1, 2017 Peer-reviewed
Daily oral intake of beta-cryptoxanthin ameliorates neuropathic pain

Gyujin Park, Tetsuhiro Horie, Takashi Iezaki, Maika Okamoto, Kazuya Fukasawa, Takashi Kanayama, Kakeru Ozaki, Yuki Onishi, Minoru Sugiura, Eiichi Hinoi

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 81(5) 1014-1017, May, 2017 Peer-reviewed
High Vitamin C Intake with High Serum beta-Cryptoxanthin Associated with Lower Risk for Osteoporosis in Post-Menopausal Japanese Female Subjects: Mikkabi Cohort Study

Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano

JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 62(3) 185-191, Jun, 2016 Peer-reviewed
High serum carotenoids are associated with lower risk for developing elevated serum alanine aminotransferase among Japanese subjects: the Mikkabi cohort study

Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano

BRITISH JOURNAL OF NUTRITION, 115(8) 1462-1469, Apr, 2016 Peer-reviewed
Serum β-cryptoxanthin and risk of high brachial-ankle pulse wave velocity: the Mikkabi cohort study.

Nakamura M, Sugiura M, Ogawa K, Ikoma Y, Yano M

Nutrition, metabolism & cardiovascular disease, 26(9) 808-814, 2016 Peer-reviewed
High serum carotenoids associated with lower risk for the metabolic syndrome and its components among Japanese subjects: Mikkabi cohort study

Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano

BRITISH JOURNAL OF NUTRITION, 114(10) 1674-1682, Nov, 2015 Peer-reviewed
Daily intake of beta-cryptoxanthin prevents bone loss by preferential disturbance of osteoclastic activation in ovariectomized mice

Kakeru Ozaki, Maika Okamoto, Kazuya Fukasawa, Takashi Iezaki, Yuki Onishi, Yukio Yoneda, Minoru Sugiura, Eiichi Hinoi

JOURNAL OF PHARMACOLOGICAL SCIENCES, 129(1) 72-77, Sep, 2015 Peer-reviewed
High serum carotenoids associated with lower risk for type 2 diabetes among Japanese subjects: Mikkabi prospective cohort study.

Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Yano M

BMJ Open Diabetes Research & Care, 3:e000147., 2015 Peer-reviewed
Prevention and reversal of lipotoxicity-induced nonalcoholic steatohepatitis by an antioxidant carotenoid, β-cryptoxanthin.

Ni Y, Nagashimada M, Zhan L, Nagata N, Kobori M, Sugiura M, Ogawa K, Kaneko S, Ota T

135(1) 67-76, 2015 Peer-reviewed
beta-Cryptoxanthin Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Suppressing Inflammatory Gene Expression in Mice

Masuko Kobori, Yinhua Ni, Yumiko Takahashi, Natsumi Watanabe, Minoru Sugiura, Kazunori Ogawa, Mayumi Nagashimada, Shuichi Kaneko, Shigehiro Naito, Tsuguhito Ota

PLOS ONE, 9(5) e98294., May, 2014
Comparison of bioavailability between beta-cryptoxanthin and beta-carotene and tissue distribution in its intact form in rats

Minoru Sugiura, Kazunori Ogawa, Masamichi Yano

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 78(2) 307-310, Feb, 2014
The Protective Effects of beta-Cryptoxanthin on Inflammatory Bone Resorption in a Mouse Experimental Model of Periodontitis

Chiho Matsumoto, Noriyuki Ashida, Satoshi Yokoyama, Tsukasa Tominari, Michiko Hirata, Kazunori Ogawa, Minoru Sugiura, Masamichi Yano, Masaki Inada, Chisato Miyaura

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 77(4) 860-862, Apr, 2013
Absorption, storage and distribution of beta-cryptoxanthin in rat after chronic administration of Japanese mandarin orange.

Sugiura M, Ogawa K, Yano M

Biological & Pharmaceutical Bulletin, 36(1) 147-151, 2013
ウンシュウミカン加工副産物の抽出物から溶媒への溶解性の差を利用してβ-クリプトキサンチンを精製する方法

小川一紀, 尾﨑嘉彦, 杉浦実

日本食品科学工学会誌, 60(9) 498-508, 2013
High Serum Carotenoids Associated with Lower Risk for Bone Loss and Osteoporosis in Post-Menopausal Japanese Female Subjects: Prospective Cohort Study

Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano

PLOS ONE, 7(12) e52643., Dec, 2012
Beta-Cryptoxanthin, Plentiful in Japanese Mandarin Orange, Prevents Age-Related Cognitive Dysfunction and Oxidative Damage in Senescence-Accelerated Mouse Brain

Keiko Unno, Minoru Sugiura, Kazunori Ogawa, Fumiyo Takabayashi, Masateru Toda, Midori Sakuma, Ken-ichi Maeda, Keisuke Fujitani, Hideaki Miyazaki, Hiroyuki Yamamoto …

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 34(3) 311-317, Mar, 2011
Dietary patterns of antioxidant vitamin and carotenoid intake associated with bone mineral density: findings from post-menopausal Japanese female subjects

M. Sugiura, M. Nakamura, K. Ogawa, Y. Ikoma, F. Ando, H. Shimokata, M. Yano

OSTEOPOROSIS INTERNATIONAL, 22(1) 143-152, Jan, 2011
β-クリプトキサンチン高含有温州ミカン果汁の摂取が脂質代謝・肝機能に及ぼす影響

大島誠, 杉浦実, 上田佳代

日本食品化学工学会誌, 102(8) 1211-1219, 2010

Misc.

Fruit consumption and lifestyle-related disease prevention

Vol 61, pp 343-347 (2003)
A cross-sectional analysis of Satsuma mandarin (Citrus unshiu Marc.) consumption and health status according to data from self-administered questionarrie.

J. Health Sci. Vol. 48, pp 366-369 (2002)
The application of the measuring apparatus of locomotor activity by infrared sensor system using a multi-Fresnel lenses to forced swimming test.

Jpn. J. Neuropsychopharmacol. Vol.19, pp.287-291 (1997)

Books and Other Publications

Nutrition and Diet in Menopause Nutrition and Health

SUGIURA Minoru

Springer Science+Business Media, 2013
Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease, 1st Edition Bioactive Foods in Chronic Disease State

SUGIURA Minoru

ELSEVIER Inc., 2011
Serum antioxidant carotenoids inversely associated with serum liver enzymes: Cross-sectional analysis from the Mikkabi Study

Acta Horticulturae, 2009
Promising pharmacological actions of crocin in Crocus sativus on the central nervous system.

Studies in Natural Product Chemistry. Bioactive Natural Products Elsevier Science Ltd., 2003
Effects of ethanol extract of Crocus Sativus L. and its purified chemicals on learning behavior and long-term potentiation.

International Academy of Biomedical and Drug Research, 1996

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