Hitoshi Ikeda - My portal - researchmap

Profile Information

Affiliation: Former Institution /Organization Department of Pathology/Pathophysiology

Degree: Doctor of Medical Science(Hokkaido University)

J-GLOBAL ID: 200901032659177380
researchmap Member ID: 1000000029

Research Interests

6

Research Areas

3

Research History

2

1985 - 1988

英国王立癌研究基金研究所研究員
1985 - 1988

Research Fellow, Imperial Cancer Research Fund

Education

2

- 1980

School of Medicine, Kanazawa Medical University
- 1980

Faculty of Medicine, Kanazawa Medical University

Committee Memberships

1

評議員, 日本病理学会

Misc.

57

Vaccination of fusion cells of rat dendritic and carcinoma cells prevents tumor growth in vivo

M Kawada, H Ikeda, T Takahashi, A Ishizu, H Ishikura, H Katoh, T Yoshiki

INTERNATIONAL JOURNAL OF CANCER, 105(4) 520-526, Jul, 2003
Vaccination of fusion cells of rat dendritic and carcinoma cells prevents tumor growth in vivo

M Kawada, H Ikeda, T Takahashi, A Ishizu, H Ishikura, H Katoh, T Yoshiki

INTERNATIONAL JOURNAL OF CANCER, 105(4) 520-526, Jul, 2003
Transduction of dominant negative ATF-1 suppresses the pX gene expression in joint fibroblastic cells derived from HTLV-I transgenic rats

A Ishizu, T Tsuji, A Abe, S Saito, T Takahashi, H Ikeda, D Meruelo, T Yoshiki

EXPERIMENTAL AND MOLECULAR PATHOLOGY, 74(3) 309-313, Jun, 2003
Transduction of dominant negative ATF-1 suppresses the pX gene expression in joint fibroblastic cells derived from HTLV-I transgenic rats

A Ishizu, T Tsuji, A Abe, S Saito, T Takahashi, H Ikeda, D Meruelo, T Yoshiki

EXPERIMENTAL AND MOLECULAR PATHOLOGY, 74(3) 309-313, Jun, 2003
Functional alteration of peripheral CD25(+)CD4(+) immunoregulatory T cells in a transgenic rat model of autoimmune diseases

M Higuchi, A Ishizu, H Ikeda, H Hayase, K Fugo, M Tsujia, A Abe, T Sugaya, A Suzuki, T Takahashi …

JOURNAL OF AUTOIMMUNITY, 20(1) 43-49, Feb, 2003
Functional alteration of peripheral CD25(+)CD4(+) immunoregulatory T cells in a transgenic rat model of autoimmune diseases

M Higuchi, A Ishizu, H Ikeda, H Hayase, K Fugo, M Tsujia, A Abe, T Sugaya, A Suzuki, T Takahashi …

JOURNAL OF AUTOIMMUNITY, 20(1) 43-49, Feb, 2003
Provirus expansion and deregulation of apoptosis-regulated genes in the spinal cord of a rat model for human T lymphocyte virus type I-associated myeloneuropathy(共著)

Journal of Neurovirology, 9,530-538, 2003
Epstein-Barr virus infection of rat lymphocytes expressing human CD21 results in restricted latent virus gene expression but not in immunoblastic transformation(共著)

Journal of Medical Viology, 70,126-130, 2003
Tissue specific high level expression of a full human endogenous retrovirus genome transgene, HERV-R, under control of its own promoter in rats(共著)

Transgenic Research, 12,319-328, 2003
Provirus expansion and deregulation of apoptosis-regulated genes in the spinal cord of a rat model for human T lymphocyte virus type I-associated myeloneuropathy "jointly worked"

Journal of Neurovirology, 9, 530-538, 2003
Epstein-Barr virus infection of rat lymphocytes expressing human CD21 results in restricted latent virus gene expression but not in immunoblastic transformation "jointly worked"

Journal of Medical Virology, 70, 126-130, 2003
Tissue specific high level expression of a full human endogenous retrovirus genome transgene, HERV-R, under control of its own promoter in rats "jointly worked"

Transgenic Research, 12, 319-328, 2003
Clonotypic analysis of T cells accumulating at arthritic lesions in HTLV-I env-pX transgenic rats

T Sugaya, A Ishizu, H Ikeda, Y Nakamaru, K Fugo, M Higuchi, H Yamazaki, K Imai, T Yoshiki

EXPERIMENTAL AND MOLECULAR PATHOLOGY, 72(1) 56-61, Feb, 2002
A novel animal model of thymic tumor: development of epithelial thymoma in transgenic rats carrying human T lymphocyte virus type I pX gene(共著)

International Journal of Experimantal Pathology, 83,247-255, 2002
The role of the thymus in development of necrotizing arthritis in transgenic rats carrying the env-pX gene of human T cell leukemia virus typeⅠ(共著)

American Journal of Pathology, 16(1), 755-761, 2002
A novel animal model of thymic tumor: development of epithelial thymoma in transgenic rats carrying human T lymphocyte virus type I pX gene "jointly worked"

International Journal of Experimental Pathology, 83, 247-255, 2002
Clonotypic analysis of T cells accumulating at arthritis lesions in HTLV-Ⅰ env-pX transgenic rats "jointly worked"

Experimental and Molecular Pathology, 72, 56-61, 2002
Immunological hyper-responsiveness in HTLV-Ⅰ LTR-env-pX transgenic rats : a prototype animal model for collagen vascular and HTLV-Ⅰ-related inflammatory diseases(共著)

Pathobiology, 69, 11-18, 2001
Immunological hyper-responsiveness in HTLV-Ⅰ LTR-env-pX transgenic rats : a prototype animal model for collagen vascular and HTLV-Ⅰ-related inflammatory diseases "jointly worked"

Pathobiology, 69, 11-18, 2001
Human T-lymphocyte virus typeⅠ(HTLV-Ⅰ)-induced myeloneuropathy in rats : Oligodendrocytes undergo apoptosis in the presence of HTLV-Ⅰ(共著)

APMIS, 108, 459-466, 2000

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Books and Other Publications

5

医療系学生のための病理学(共著)

講談社, 1999
HTLV-I感染モデルラット-特にHAM発症ラットについて-(共著)

バイオメディカルリサーチマニュアル養賢堂, 1995
主要組織適合抗原(HLA)の構造と発現

分子病理学(杉山武敏編)文光堂, 1993
A rat model of HTLV-I infection "jointly worked" In Advances in adult T cell leukemia and HTLV-I research

Japan Scientific Scienties Press, CRC Press, 1992
Analysis of HLA-class II products by DNA-mediated gene transfer "jointly worked" In Molecular Biology of HLA-class II Antigens

CRC Press, 1989

Professional Memberships

7

Research Projects

6

癌特異的形質の検討と治療に関する基礎的研究

2000
Analysis of Cancer Specific Characteristics and Basic Trial for Advanced Cancer Therapy

2000
ヒト内在性レトロウイルスの病理学的解析

科学研究費補助金, 1989
動物モデルを用いたHTLV-I感染症の解析

科学研究費補助金, 1989
Pathological Analysis of Human Endogenous Retroviruses

Grant-in-Aid for Scientific Research, 1989
Analysis of HTLV-I Infectious Diseases using Animal Models

Grant-in-Aid for Scientific Research, 1989