Kazuo Miyashita

Profile Information

Affiliation: Professor, Faculty of Fisheries Sciences, Division of Marine Life Science, Hokkaido University

Degree: (BLANK)
Doctor (Agriculture)(Tohoku University)

J-GLOBAL ID: 200901095571170743
researchmap Member ID: 1000001096

Research Interests

Research Areas

Research History

Apr, 2014 - Present

Vice Dean, Faculty of Fisheries Sciences, Hokkaido University
Apr, 2005 - Present

Professor, Faculty of Fisheries Sciences
Apr, 2000 - Mar, 2005

Professor, Graduate School of Fisheries Sciences
Apr, 1995 - Mar, 2000

Associate Professor, Faculty of Fisheries
1995 - 2000

Associate Professor in Chemistry,
2000

- Professor,
Jul, 1985 - Mar, 1995

Instructor, Faculty of Fisheries
1985 - 1995

Instructor of Chemistry,
Graduate School of Fisheries Sciences,
Division of Bioscience,
Bio-functional Material Chemistry,
Faculty of Fisheries,

Education

Apr, 1980 - Mar, 1985

Graduate School of Agriculture, Tohku University
- 1985

Graduate School, Division of Agriculture, Tohoku University
Apr, 1975 - Mar, 1979

Faculty of Agriculture, Tohoku University
- 1979

Faculty of Agriculture, Tohoku University

Committee Memberships

2018 - Present

President, 国際機能性食品学会(ISNFF)
2015 - Present

学術専門委員会委員長, 日本油化学会
2013 - Present

参与, 日本農芸化学会
2012 - Present

理事, 日本油化学会
2011 - Present

Member at Large, 国際機能性食品学会(ISNFF)
2011 - Present

Asian Section Chair, 米国油化学会(AOCS)
2011 - Present

代議員, 日本栄養食糧学会
2011 - Present

編集委員, 日本水産学会
2011 - Present

理事, 日本フードファクター学会
2010 - Present

連携会員, 日本学術会議
2009 - Present

International Advisory Boad, 国際機能性食品学会(ISNFF)
2006 - Present

学術専門委員会委員, 日本油化学会
2006 - Present

評議員, 日本フードファクター学会
2003 - Present

編集委員（Editor）, 韓国食品科学会（Korean Society of Food and Tecnology）
2003 - Present

評議員, 脂質栄養学会
2003 - Present

代議員, 日本油化学会
2003 - Present

関東支部幹事, 日本油化学会
2001 - Present

幹事, 日本脂質生化学研究会
2014 - 2016

会長, 日本油化学会
2011 - 2014

JOS編集委員長, 日本油化学会

Awards

May, 2018

Kaufman Memorial Lecture Award, International Society for Fat Research (ISF)

MIYASHITA Kazuo
Aug, 2015

Fellow of the American Chemical Society, American Chemical Society

MIYASHITA Kazuo
Jun, 2012

Technology Innovation Award 2012 of the Japanese Society for Marine Biotecnology

MIYASHITA Kazuo
Nov, 2011

2011 Award (International Society for Nutraceutical and Functuional Foods)

MIYASHITA Kazuo
Sep, 2011

日本カロテノイド研究会研究会受賞

宮下和夫
Jun, 2007

Division Lecture’s Award (Food Chemistry Division; IFT)

MIYASHITA Kazuo
Jul, 2006

Bio-business Competition Japan 2006 Award

MIYASHITA Kazuo
Mar, 2006

JOCS (Japanese Oil Chemists’ Society) Award

MIYASHITA Kazuo
Mar, 2006

The Japanese Society of Fisheries Science Award

Papers

122

Antioxidant activity, total phenolics and flavonoids contents: Should we ban in vitro screening methods?

Daniel Granato, Fereidoon Shahidi, Ronald Wrolstad, Paul Kilmartin, Laurence D. Melton, Francisco J. Hidalgo, Kazuo Miyashita, John van Camp, Cesarettin Alasalvar, Amin B. Ismail …

Food Chemistry, 264 471-475, Oct 30, 2018 Peer-reviewed
Effective Prevention of Oxidative Deterioration of Fish Oil: Focus on Flavor Deterioration

Kazuo Miyashita, Mariko Uemura, Masashi Hosokawa

Annual Review of Food Science and Technology, 9 209-226, Mar 25, 2018 Peer-reviewed
酸化しないオメガ3高度不飽和脂肪酸素材の開発

JATFF ジャーナル, 6(5) 45-50, 2018 Peer-reviewed
高度不飽和脂肪酸に対するスフィンゴイド塩基とα-トコフェロールの相乗的抗酸化効果

宮下和夫, 上村麻梨子, 細川雅史

オレオサイエンス, 18 317-324, 2018 Peer-reviewed
Health impact of marine carotenoids.

Miyashita, K, Hosokawa, M

J. Food Bioact. 1:31-40 (2018), 1 34-40, 2018 Peer-reviewed
Acrolein as a major volatile in the early stages of fish oil TAG oxidation

Ako Shibata, Mariko Uemura, Masashi Hosokawa, Kazuo Miyashita

Journal of Oleo Science, 67(5) 515-524, 2018 Peer-reviewed
Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells.

Terasaki, M, Mima, M, Ludoh, S, Endo, T, Maeda, H, Hamada, J, Osada, K, Miyashita, K, Mutoh, M

Oncology Rep., 40(1) 414-424, 2018 Peer-reviewed
Comparison of oxidative stability of monogalactosyl diacylglycerol, digalactosyl diacylglycerol, and triacylglycerol containing polyunsaturated fatty acids.

Hazahari, N.Y, B, Hosokawa, M, Miyashita, K

Food Nutr. Sci., 9 221-234, 2018 Peer-reviewed
Seasonal variation in nutritional composition and anti-proliferative activity of brown seaweed, Sargassum oligocystum.

Praiboon, J, Palakas, S, Noiraksa, T, Miyashita, K

J. Appl. Phycol., 30 101-111, 2018 Peer-reviewed
Spatial and seasonal variations in the biofunctional lipid substances (fucoxanthin and fucosterol) of the laboratory-grown edible Japanese seaweed (Sargassum horneri Turner) cultured in the open sea

Masaru Terasaki, Chikara Kawagoe, Atsushi Ito, Hiroko Kumon, Bhaskar Narayan, Masashi Hosokawa, Kazuo Miyashita

SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 24(7) 1475-1482, Nov, 2017 Peer-reviewed
Docosapentaenoic Acid (22:5n-3) Downregulates mRNA Expression of Pro-inflammatory Factors in LPS-activated Murine Macrophage Like RAW264.7 Cells

Yanzhu Tian, Ami Katsuki, Donato Romanazzi, Matthew R. Miller, Serean L. Adams, Kazuo Miyashita, Masashi Hosokawa

JOURNAL OF OLEO SCIENCE, 66(10) 1149-1156, Oct, 2017 Peer-reviewed
Fucoxanthin in the management of obesity and its related disorders

Kazuo Miyashita, Masashi Hosokawa

JOURNAL OF FUNCTIONAL FOODS, 36 195-202, Sep, 2017 Peer-reviewed
Fatty Acid and Lipid Class Composition of the Microalga Phaeodactylum tricornutum

Yang, Yu-Hong, Du, Lei, Hosokawa, Masashi, Miyashita, Kazuo, Kokubun, Yume, Arai, Hisayoshi, Taroda, Hiroyuki

JOURNAL OF OLEO SCIENCE, 66(4) 363-368, Apr, 2017 Peer-reviewed
Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol

Masaru Terasaki, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 69(7) 1043-1052, 2017 Peer-reviewed
Reduction of HbA1c levels by fucoxanthin-enriched akamoku oil possibly involves the thrifty allele of uncoupling protein 1 (UCP1): a randomized controlled trial in normal-weight and obese Japanese adults.

Mikami, N, Hosokawa, M, Miyashita, K, Sohma, H, Ito, Y. M, Kokai, Y

J. Nutr. Sci., 6 e5, 2017 Peer-reviewed
Squalene modulates fatty acid metabolism: Enhanced EPA/DHA in obese/diabetic mice (KK-A(y)) model

Sangeetha Ravi Kumar, Ippei Yamauchi, Bhaskar Narayan, Ami Katsuki, Masashi Hosokawa, Kazuo Miyashita

EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 118(12) 1935-1941, Dec, 2016 Peer-reviewed
Bioconversion of Docosapentaenoic Acid in Human Cell Lines, Caco-2, HepG2, and THP-1

Yanzhu Tian, Donato Romanazzi, Kazuo Miyashita, Masashi Hosokawa

JOURNAL OF OLEO SCIENCE, 65(12) 1017-1022, Dec, 2016 Peer-reviewed
Inhibitory Effect of Dihydrosphingosine with alpha-Tocopherol on Volatile Formation during the Autoxidation of Polyunsaturated Triacylglycerols

Mariko Uemura, Ako Shibata, Masashi Hosokawa, Ai Iwashima-Suzuki, Makoto Shiota, Kazuo Miyashita

JOURNAL OF OLEO SCIENCE, 65(9) 713-722, Sep, 2016 Peer-reviewed
Factors influencing the induction of adventitious bud and callus in the brown alga Sargassum horneri (Turner) C. Agardh

Toshiki Uji, Daisuke Nanaumi, Chikara Kawagoe, Naotsune Saga, Kazuo Miyashita

JOURNAL OF APPLIED PHYCOLOGY, 28(4) 2435-2443, Aug, 2016 Peer-reviewed
Fabrication of Fucoxanthin-Loaded Microsphere (F-LM) By Two Steps Double-Emulsion Solvent Evaporation Method and Characterization of Fucoxanthin before and after Microencapsulation

Dedi Noviendri, Irwandi Jaswir, Muhammad Taher, Farahidah Mohamed, Hamzah Mohd Salleh, Ibrahim Ali Noorbatcha, Fitri Octavianti, Widya Lestari, Ridar Hendri, Hasna Ahmad …

JOURNAL OF OLEO SCIENCE, 65(8) 641-653, Aug, 2016 Peer-reviewed

Misc.

Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo

K Shiratori, K Ohgami, Ilieva, I, XH Jin, Y Koyama, K Miyashita, K Yoshida, S Kase, S Ohno

EXPERIMENTAL EYE RESEARCH, 81(4) 422-428, Oct, 2005
Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPAR gamma in human colon cancer Caco-2 cells

Y Yasui, M Hosokawa, T Sahara, R Suzuki, S Ohgiya, H Kohno, T Tanaka, K Miyashita

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 73(2) 113-119, Aug, 2005
Docosahexaenoic acid-containing phosphatidylethanolamine enhances HL-60 cell differentiation by regulation of c-jun and c-myc expression

H Ishigamori, M Hosokawa, H Kohno, T Tanaka, K Miyashita, K Takahashi

MOLECULAR AND CELLULAR BIOCHEMISTRY, 275(1-2) 127-133, Jul, 2005
Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues

H Maeda, M Hosokawa, T Sashima, K Funayama, K Miyashita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 332(2) 392-397, Jul, 2005
海藻由来フコキサンチンの脂肪細胞に対する分化調節機能と抗肥満効果

食品工業, 48, 2005
Analysis of conjugated linoleic acids as 9-anthrylmethyl esters by reversed-phase high-performance liquid chromatography with fluorescence detection

J. Chromatogra. Sci., 43, 2005
Lipid peroxidation of a human hepatoma cell line (HepG2) after incorporation of linoleic acid, arachidonic acid, and docosahexaenoic acid.

Biosci. Biotechnol. Biochem., 69, 2005
Bacterial microflora of carp (Cyprinus carpio) and its shelf-life extension by essential oil compounds

BSM Mahmoud, K Yamazaki, K Miyashita, SI Shik, C Dong-Suk, T Suzuki

FOOD MICROBIOLOGY, 21(6) 657-666, Dec, 2004
Dietary seed oil rich in conjugated linolenic acid from bitter melon inhibits azoxymethane-induced rat colon carcinogenesis through elevation of colonic PPAR gamma expression and alteration of lipid composition

H Kohno, Y Yasui, R Suzuki, M Hosokawa, K Miyashita, T Tanaka

INTERNATIONAL JOURNAL OF CANCER, 110(6) 896-901, Jul, 2004
Separation of sardine oil without heating from surimi waste and its effect on lipid metabolism in rats

K Toyoshima, R Noguchi, M Hosokawa, K Fukunaga, T Nishiyama, R Takahashi, K Miyashita

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 52(8) 2372-2375, Apr, 2004
カズノコは優れた栄養機能食品

食の科学, 314, 2004
共役型リノレン酸のがん予防効果

日本がん予防学会ニュースレター, 40, 2004
Ｏ/Ｗエマルションの界面化学特性と脂質酸化

FFIジャーナル, 209, 2004
Growth inhibition of human pro-myelocytic leukemia (HL-60) cells by lipid extracts of marine alga Sargassum marginatum (Fucales, Phaeophyta) harvested off Goa (west coast of India) with special reference to fatty acid composition.

Indian J. Marine Sci., 33, 2004
Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARγligand, troglitazone, on colon cancer cells.

Biochim. Biophys. Acta, 1675, 2004
Comparative evaluation of fatty acid composition of different Sargassum (Fucales, Phaeophyta) species harvested from temperate and tropical waters

Bhaskar Narayan, Kazuo Miyashita, Masashi Hosakawa

Journal of Aquatic Food Product Technology, 13(4) 53-70, 2004
Conjugated linoleic acid deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin.

J. Nutr. Sci. Vitaminol., 50, 2004
Decontamination effect of electrolyzed NaCl solutions on carp.

Lett. Appl. Micro., 396, 2004
Control of life cycle of mouse adipogenic 3T3-L1 cells by dietary lipids and metabolic factors.

Applied Biochem. Biotech., 118, 2004
Comparative study on the autoxidation of TAG containing conjugated and nonconjugated C18 PUFA.

J. Am. Oil Chem. Soc., 81, 2004

Books and Other Publications

酸化防止. 「油脂・脂質の基礎と応用」

日本油化学会, 2004
酸化防止. 「水産機能性脂質-給源・機能･利用-」

恒星社厚生閣, 2004
Antioxidant Activity of Electrolyzed Sodium Chloride in Food Factors in Health Promotion and Disease Prevention

American Chemical Society, 2003
機能性脂質の新展開

2001
脂質栄養と脂質過酸化物-生体内脂質過酸化は傷害か防御か-

学会センター関西, 1998
過酸化脂質・フリーラジカル実験法

学会出版センター, 1995
油脂化学便覧

丸善, 1990

Professional Memberships

Works

海藻の有効活用に関する研究

宮下和夫

2005 - Present Artistic work
カロテノイドの生理活性に関する研究

宮下和夫

2005 - Present Artistic work
海洋資源の有効活用

2005 - Present
肥満・脂肪代謝制御の分子機構と食品中の活性化因子に関する研究

1999 - Present
食品での脂質過酸化と抗酸化に関する研究

1995 - Present
三陸産未利用水産資源を活用した新規機能性食品素材の開発

2005 - 2007
食品成分に含まれる抗肥満物質の探索と利用に関する研究

2005 - 2006
エマルション中の油脂の酸化防止

2004 - 2006
マイクロナノスフィアの界面化学特性の解明

2002 - 2006
Analysis of interfacial characteristics of micro/nano-particle in emulsion

2002 - 2006
Physiological effects of conjugated fatty acids Conjugated fatty acids, anticancer

2001 - 2006
Study on the functionality of lipid related compounds in food materials and their chemical and biological properties

1999 - 2006
Study on the oxidation and antioxidation of polyunsaturated lipids

1995 - 2006
亜臨界技術を応用した水産由来機能性物質に関する研究

2005
水産脂質の機能性を活用した新規食品素材の開発

2004
共役脂肪酸の生理機能に関する研究

2001 - 2002

Research Projects

三陸沿岸域の特性やニーズを基盤とした海藻産業イノベーション

東北マリンサイエンス拠点形成事業（新たな産業の創成につながる技術開発）, 文部科学省, 2011 - 2015

宮下和夫
農産廃棄物カスケード型循環利用バイオエタノール製造システムに関する研究

循環型社会形成推進科学研究費補助金, 環境省, 2011 - Mar, 2014

宮下和夫
アレンカロテノイドの生体内局在と機能解析

科学研究費・基盤研究(B), 日本学術振興会, 2011 - Mar, 2014

宮下和夫
函館マリンバイオクラスター（UMI＜Universal Marine Industry＞のグリーンイノベーション）

地域イノベーション戦略支援プログラム(グローバル型)（文部科学省）, 文部科学省, 2008 - 2013

宮下和夫
さっぽろバイオクラスター“Bio-S”

地域イノベーション戦略支援プログラム(グローバル型)（文部科学省）, 文部科学省, 2007 - Mar, 2012

宮下和夫
海藻製品中のHUFAはなぜ酸化されにくいのか？

科学研究費補助金・萌芽研究, 日本学術振興会, 2011 - 2012

宮下和夫
食品素材中の脂肪酸関連有効成分の検索とその食品化学的特性に関する研究

官民連帯共同研究, 1999 - 2008
食品での脂質過酸化と抗酸化に関する研究

その他の研究制度, 1995 - 2008
水産機能性成分の単分散マイクロナノスフィア化による安定性向上及び吸収性の向上

科学研究費補助金・基盤研究(C), 日本学術振興会, 2003 - Mar, 2006

宮下和夫
マイクロナノスフィアの界面化学特性の解明

農林水産業特別試験研究費補助金, 2002 - 2006
Analysis of interfacial characteristics of micro/nano-particle in emulsion

0066 (Japanese Only), 2002 - 2006
共役脂肪酸の生理機能に関する研究

科学研究費補助金, 2001 - 2006
Study on the oxidation and antioxidation of polyunsaturated lipids

The Other Research Programs, 1995 - 2005
Study on the functionality of lipid related compounds in food materials and their chemical and biological properties

Promotion of Basic Research Activities for Innovative Biosciences, 1999 - 2003
Physiological effects of conjugated fatty acids

Grant-in-Aid for Scientific Research, 2001 - 2002
海藻の機能性と有効利用
水産脂質の機能性と有効利用
Effective Utilization of Seaweed
Functionality and Effective Utilization of Marine Lipids
Effective Utilization of Bitter Gourd

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Professional Memberships

Works

Research Projects

Industrial Property Rights

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