嘉屋俊二 (Shunji Kaya) - マイポータル - researchmap

基本情報

所属: 旧所属北海道大学大学院理学研究院化学部門助教授

学位: 理学博士(北海道大学)

J-GLOBAL ID: 200901092483425180
researchmap会員ID: 1000001747

研究キーワード

4

研究分野

2

経歴

4

1994年 - 1995年

北海道大学講師
1994年 - 1995年

北海道大学
1986年 - 1994年

北海道大学助手
1986年 - 1994年

Hokkaido University, Research Assistant

学歴

4

MISC

20

Evidence for a relationship between activity and the tetraprotomeric assembly of solubilized pig gastric H/K-ATPase

K Abe, S Kaya, K Taniguchi, Y Hayashi, T Imagawa, M Kikumoto, K Oiwa, K Sakaguchi

JOURNAL OF BIOCHEMISTRY 138(3) 293-301 2005年9月
Thr-774 (transmembrane segment M5), Val-920 (M8), and Glu-954 (M9) are involved in Na+ transport, and Gln-923 (m8) is essential for Na,K-ATPaseActivity

T Imagawa, T Yamamoto, S Kaya, K Sakaguchi, K Taniguchi

JOURNAL OF BIOLOGICAL CHEMISTRY 280(19) 18736-18744 2005年5月
The Amino Acid Sequence 442GDASE446 in Na/K-ATPase Is an Important Motif in Forming the High and Low Affinity ATP Binding Pockets

Toshiaki Imagawa, Shunji Kaya, Kazuya Taniguchi

Journal of Biological Chemistry 278(50) 50283-50292 2003年12月12日
The amino acid sequence (442)GDASE(446) in Na/K-ATPase is an important motif in forming the high and low affinity ATP binding pockets

T Imagawa, S Kaya, K Taniguchi

JOURNAL OF BIOLOGICAL CHEMISTRY 278(50) 50283-50292 2003年12月
Tetraprotomeric structure of pig gastric H/K-ATPase: Investigation of H/K-ATPase by single-molecule detection techniques

Biochemistry 42, 15132-15138 2003年
Tetraprotomeric structure of pig gastric H/K-ATPase: Investigation of H/K-ATPase by single-molecule detection techniques

Biochemistry 42, 15132-15138 2003年
Conformational change induced by tyrosine phosphorylation of the N-terminal domain of the α-chain of pig gastric H⁺/K⁺-ATPase.

Biochem. Biophys. Res. Commun 300 223-229 2003年
Replacement of several single amino acid side chains exposed to the inside of the ATP-binding pocket induces different extents of affinity change in the high and low affinity ATP-binding sites of rat Na/K-ATPase

S Teramachi, T Imagawa, S Kaya, K Taniguchi

JOURNAL OF BIOLOGICAL CHEMISTRY 277(40) 37394-37400 2002年10月
Gastric H/K-ATPase liberates two moles of Pi from one mole of phosphoenzyme formed from a high-affinity ATP binding site and one mole of enzyme-bound ATP at the low affinity site during cross-talk between catalytic subunits.

Biochemistry 192 438-2445 2002年
The oligomeric nature of Na/K-transport ATPase

K Taniguchi, S Kaya, K Abe, S Mardh

JOURNAL OF BIOCHEMISTRY 129(3) 335-342 2001年3月
Membrane enzyme systems responsible for the Ca2+-dependent phosphorylation of Ser(27), the independent phosphorylation of Tyr(10) and Tyr(7), and the dephosphorylation of these phosphorylated residues in the alpha-chain of H/K-ATPase

M Kanagawa, S Watanabe, S Kaya, K Togawa, T Imagawa, A Shimada, K Kikuchi, K Taniguchi

JOURNAL OF BIOCHEMISTRY 127(5) 821-828 2000年5月
Acid-labile ATP and/or ADP/P-i binding to the tetraprotomeric form of Na/K-ATPase accompanying catalytic phosphorylation-dephosphorylation cycle

T Yokoyama, S Kaya, K Abe, K Taniguchi, T Katoh, M Yazawa, Y Hayashi, S Mardh

JOURNAL OF BIOLOGICAL CHEMISTRY 274(45) 31792-31796 1999年11月
ATP and Acetyl Phoshate Induces Molecular Events near the ATP binding Site and the Membrane Domain of Na⁺, K+-ATPase : The Tetrameric Nature of the Enzyme2

JE/The Journal of Biological Chemistry 273(38) 24339-24345 1998年
Ser-27, Tyr-10 and Tyr-7 in the α-chain of pig stomach H⁺, K⁺-ATPase as Ca²⁺ dependent phosphorylatatable sites by intrinsic and extrinsic protein kinases.

Biochem. Biophys. Res. Commun 227(3) 810-815 1996年
Reversible phosphorylation of both Tyr7 and Tyr10 in the α-chain of pig stomach H⁺, K⁺-ATPase by a membrane-bound kinase and phosphatase

J. Biol. Chem. 269 7419-7422 1995年
AN EXTRA PHOSPHORYLATION OF NA+,K+-ATPASE BY PARANITROPHENYLPHOSPHATE (PNPP) - EVIDENCE FOR THE OLIGOMERIC NATURE OF THE ENZYME

A YAMAZAKI, S KAYA, T TSUDA, Y ARAKI, Y HAYASHI, K TANIGUCHI

JOURNAL OF BIOCHEMISTRY 116(6) 1360-1369 1994年12月
Different susceptibility to phosholipase A2 treatment of the fluorescence intensity changes in the vicinity of Cys-964 and Lys-501 in the α-chain of probe labeled Na⁺-K⁺-ATPase

The journal of Biochemistry 115,454-462 1994年
Pyrinodxal-5'-phosphate Probe at Lys 480 can sences the binding of ATP and the formation of phosphoenzyme in Na⁺-K⁺-ATPase

the Journal of Biological Chemistry 19(269) 7419-7422 1994年
Phosphorylation of half and full sites in H⁺, K⁺-ATPase results in opposite changes in tryptphan fluorescence

Biochemical and Biophysical Research Communication 196(294-300) 1993年
THE RAT H+ K+-ATPASE BETA-SUBUNIT GENE AND RECOGNITION OF ITS CONTROL REGION BY GASTRIC DNA-BINDING PROTEIN

M MAEDA, KI OSHIMAN, S TAMURA, S KAYA, S MAHMOOD, MA REUBEN, LS LASATER, G SACHS, M FUTAI

JOURNAL OF BIOLOGICAL CHEMISTRY 266(32) 21584-21588 1991年11月

書籍等出版物

2

Oligomeric structure of P-type ATPases observed by single molecule detection technique.

Ann. N.Y. Acad. Sci. 2003年
Pyridoxal-5'-phosphate Probe at Lys 480 can Monitor Conformational Events Induced by Acetyl Phosphate in Na⁺/K⁺-ATPase

The sodium pump(E. Bamberg and W. Schoner Ed. ) Steinkopff Darmstadt Springer New York 1994年

所属学協会

1

日本生化学会

共同研究・競争的資金等の研究課題

4