Igarashi I.

J-GLOBAL         Last updated: Aug 18, 2019 at 17:16
 
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Name
Igarashi I.
Affiliation
Obihiro University of Agriculture and Veterinary Medicine
Section
National Research Center for Protozoan Diseases
Job title
Professor
Degree
Ph.D(Gunma University), Master of Veterinary Medicine(Obihiro University of Agriculture and Veterinary Medicine)

Profile

I have been working on protozoan diseases including toxoplasmosis, malaria and babesiosis. Last 10 years, I have been devoted to the development of serological and molecular diagnoses, searching potential anti-Babesia drugs, molecular epidemiology for Babesia infections. I have supervised many PhD students and published more than 240 papers in peer-reviewed journals. I also contributed to parasitlogy community as the editorial board of Veterinary Parasitology, academic editor for PLOS ONE and reviewers for many other journals.

Research Areas

 
 
  • Zootechnical science/Veterinary medical science / Applied veterinary science / animal science, veterinary medicine, protozoology

Academic & Professional Experience

 
Feb 2002
 - 
Mar 2010
Director, National Research Center for Protozoan Diseases
 
Feb 1985
 - 
Jan 1988
Research Associate, Institute of Pathology, Case Western Reserve University
 
May 1983
 - 
Feb 1988
Assistane Professor, Department of Medical Parasitology, School of Medicine, Gunma University
 
Mar 1988
 - 
May 1991
Assistant Professor, Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine
 
May 1989
 - 
May 1991
Long term expert, Deputy Team leader, Japan International Cooperation Agency
 
Jun 1991
 - 
Jul 1991
Assistane Profesoor, Research Center for Protozoan Molecular Immunology, Obihiro University of Agriculture and Veterinary Medicine
 
Aug 1991
 - 
Mar 2000
Associate Professor, Research Center for Protozoan Molecular Immunology, Obihiro University of Agriculture and Veterinary Medicine
 
Oct 2002
 - 
Mar 2007
Project leader for 21st Century COE program, Obihiro University of Agriculture and Veterinary Medicine
 
Apr 2000
 - 
Mar 2009
Professor ( concurrent), United Graduate School of Veterinary Science, Gifu University
 
Feb 2002
 - 
Mar 2010
Director, National Research Center for Protozoan iseases
 
Apr 2000
 - 
Today
Professor, National Research Center for Protozoan iseases
 
Apr 2006
 - 
Today
Profesoor, Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine
 
May 2007
 - 
Today
Expert of bovine babesiosos and equine piroplasmaosis, World Organisation for Animal Health (OIE)
 

Education

 
Apr 1979
 - 
Mar 1983
Social Medicine (Parasitology), Graduate School of Medicine, Gunma University
 
Apr 1977
 - 
Mar 1979
Veterinary Medicine, Graduate School of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
 
Apr 1973
 - 
Mar 1977
Veterinary Medicine, Faculty of Animal Science, Obihiro University of Agriculture and Veterinary Medicine
 

Committee Memberships

 
2005
   
 
World Association for Advancedment of Veterinary Parasitology  Editorial Board Member, Vterinary Parasitology
 
2001
   
 
Japanese Society for Tropical medicine and Hygiene  Coucilor
 
2000
   
 
Japnese Societ of Veterinary Science  Councilor
 
1999
   
 
American Society for Microbiology  Member
 
1999
   
 
Australian Society for parasitology  Member
 
1992
   
 
Japanese Socciety of Parasitology  Councilor
 
1990
   
 
World Association for Advancement of Veterinary Parasitology  Member
 

Awards & Honors

 
Mar 2018
Studies on development of diagnostics and treatment for piroplamosis, Katsurada Award
 
Apr 2000
Establishment of in vitro culture of Babesia and it's application for chemotherapy and dianosis, Veterinary Science Award, The Japanese Society of Veterinary Science
 

Published Papers

 
Tayebwa DS, Vudriko P, Tuvshintulga B, Guswanto A, Nugraha AB, Gantuya S, Batiha GE, Musinguzi SP, Komugisha M, Bbira JS, Okwee-Acai J, Tweyongyere R, Wampande EM, Byaruhanga J, Adjou Moumouni PF, Sivakumar T, Yokoyama N, Igarashi I
Ticks and tick-borne diseases   9(6) 1475-1483   Sep 2018   [Refereed]
Sivakumar T, Tuvshintulga B, Zhyldyz A, Kothalawala H, Yapa PR, Kanagaratnam R, Vimalakumar SC, Abeysekera TS, Weerasingha AS, Yamagishi J, Igarashi I, Silva SSP, Yokoyama N
Journal of clinical microbiology      Aug 2018   [Refereed]
Ybañez AP, Ybañez RHD, Talle MG, Arreglo RMT, Geens MJC, Villas JGI 3rd, Villar SR, Laruga CL, Cao S, Moumouni FPA, Liu M, Igarashi I, Xuan X
Ticks and tick-borne diseases   9(5) 1125-1128   Jul 2018   [Refereed]
Tayebwa DS, Tuvshintulga B, Guswanto A, Nugraha AB, Batiha GE, Gantuya S, Rizk MA, Vudriko P, Sivakumar T, Yokoyama N, Igarashi I
Ticks and tick-borne diseases   9(5) 1192-1201   Jul 2018   [Refereed]
Shibata S, Sivakumar T, Igarashi I, Umemiya-Shirafuji R, Inokuma H, Fukumoto S, Yokoyama N
Ticks and tick-borne diseases   9(5) 1235-1240   Jul 2018   [Refereed]
Umemiya-Shirafuji R, Hatta T, Okubo K, Sato M, Maeda H, Kume A, Yokoyama N, Igarashi I, Tsuji N, Fujisaki K, Inoue N, Suzuki H
Acta parasitologica   63(2) 433   Jun 2018   [Refereed]
Guswanto A, Nugraha AB, Tuvshintulga B, Tayebwa DS, Rizk MA, Batiha GE, Gantuya S, Sivakumar T, Yokoyama N, Igarashi I
International journal for parasitology. Drugs and drug resistance   8(1) 104-111   Apr 2018   [Refereed]
Sivakumar T, Lan DTB, Long PT, Viet LQ, Weerasooriya G, Kume A, Suganuma K, Igarashi I, Yokoyama N
The Journal of veterinary medical science   80(2) 333-336   Mar 2018   [Refereed]
Rizk MA, AbouLaila M, El-Sayed SAE, Guswanto A, Yokoyama N, Igarashi I
Infection and drug resistance   11 1605-1615   2018   [Refereed]
El-Sayed SAE, Rizk MA, Terkawi MA, Yokoyama N, Igarashi I
Parasitology international   66(6) 721-726   Dec 2017   [Refereed]
Umemiya-Shirafuji R, Hatta T, Okubo K, Sato M, Maeda H, Kume A, Yokoyama N, Igarashi I, Tsuji N, Fujisaki K, Inoue N, Suzuki H
Acta parasitologica   62(4) 836-841   Dec 2017   [Refereed]
Guswanto A, Allamanda P, Mariamah ES, Sodirun S, Wibowo PE, Indrayani L, Nugroho RH, Wirata IK, Jannah N, Dias LP, Wirawan HP, Yanto R, Tuvshintulga B, Sivakumar T, Yokoyama N, Igarashi I
Parasites & vectors   10(1) 550   Nov 2017   [Refereed]
Ishizaki T, Sivakumar T, Hayashida K, Takemae H, Tuvshintulga B, Munkhjargal T, Guswanto A, Igarashi I, Yokoyama N
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   54 138-145   Oct 2017   [Refereed]
Rizk MA, El-Sayed SAE, AbouLaila M, Eltaysh R, Yokoyama N, Igarashi I
Scientific reports   7(1) 12774   Oct 2017   [Refereed]
Tuvshintulga B, AbouLaila M, Sivakumar T, Tayebwa DS, Gantuya S, Naranbaatar K, Ishiyama A, Iwatsuki M, Otoguro K, Ōmura S, Terkawi MA, Guswanto A, Rizk MA, Yokoyama N, Igarashi I
Scientific reports   7(1) 13888   Oct 2017   [Refereed]
Badral D, Odonbayar B, Murata T, Munkhjargal T, Tuvshintulga B, Igarashi I, Suganuma K, Inoue N, Brantner AH, Odontuya G, Sasaki K, Batkhuu J
Journal of natural products   80(9) 2416-2423   Sep 2017   [Refereed]
Rizk MA, El-Sayed SAE, AbouLaila M, Yokoyama N, Igarashi I
Experimental parasitology   179 43-48   Aug 2017   [Refereed]
Kamyingkird K, Cao S, Tuvshintulga B, Salama A, Mousa AA, Efstratiou A, Nishikawa Y, Yokoyama N, Igarashi I, Xuan X
Experimental parasitology   176 59-65   May 2017   [Refereed]
Guswanto A, Allamanda P, Mariamah ES, Munkjargal T, Tuvshintulga B, Takemae H, Sivakumar T, AbouLaila M, Terkawi MA, Ichikawa-Seki M, Nishikawa Y, Yokoyama N, Igarashi I
Veterinary parasitology   239 76-79   May 2017   [Refereed]
Fereig RM, Mohamed SGA, Mahmoud HYAH, AbouLaila MR, Guswanto A, Nguyen TT, Ahmed Mohamed AE, Inoue N, Igarashi I, Nishikawa Y
Ticks and tick-borne diseases   8(1) 125-131   Jan 2017   [Refereed]
Wang G, Efstratiou A, Adjou Moumouni PF, Liu M, Jirapattharasate C, Guo H, Gao Y, Cao S, Mo Zhou, Suzuki H, Igarashi I, Xuan X
Experimental parasitology   172 5-11   Jan 2017   [Refereed]
Maeda H, Hatta T, Alim MA, Tsubokawa D, Mikami F, Matsubayashi M, Miyoshi T, Umemiya-Shirafuji R, Kawazu SI, Igarashi I, Mochizuki M, Tsuji N, Tanaka T
Scientific reports   6 37039   Nov 2016   [Refereed]
Wang G, Efstratiou A, Adjou Moumouni PF, Liu M, Jirapattharasate C, Guo H, Gao Y, Cao S, Zhou M, Suzuki H, Igarashi I, Xuan X
Experimental parasitology   169 6-12   Oct 2016   [Refereed]
Sivakumar T, Igarashi I, Yokoyama N
Veterinary parasitology   229 99-106   Oct 2016   [Refereed]
Weerasooriya G, Sivakumar T, Lan DT, Long PT, Takemae H, Igarashi I, Inoue N, Yokoyama N
The Journal of veterinary medical science   78(8) 1361-1367   Sep 2016   [Refereed]
Munkhjargal T, Yokoyama N, Igarashi I
Parasitology research   115(9) 3669-3676   Sep 2016   [Refereed]
Rizk MA, El-Sayed SA, AbouLaila M, Tuvshintulga B, Yokoyama N, Igarashi I
Veterinary parasitology   227 93-97   Aug 2016   [Refereed]
Ishizaki T, Sivakumar T, Hayashida K, Tuvshintulga B, Igarashi I, Yokoyama N
Experimental parasitology   166 10-15   Jul 2016   [Refereed]
Munkhjargal T, Aboge GO, Ueno A, Aboulaila M, Yokoyama N, Igarashi I
Experimental parasitology   166 29-36   Jul 2016   [Refereed]
Tattiyapong M, Sivakumar T, Takemae H, Simking P, Jittapalapong S, Igarashi I, Yokoyama N
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   41 255-261   Jul 2016   [Refereed]
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, Baker S, Ben Mamoun C, Bhatia S, Bickle Q, Bounaadja L, Bowling T, Bosch J, Boucher LE, Boyom FF, Brea J, Brennan M, Burton A, Caffrey CR, Camarda G, Carrasquilla M, Carter D, Belen Cassera M, Chih-Chien Cheng K, Chindaudomsate W, Chubb A, Colon BL, Colón-López DD, Corbett Y, Crowther GJ, Cowan N, D'Alessandro S, Le Dang N, Delves M, DeRisi JL, Du AY, Duffy S, Abd El-Salam El-Sayed S, Ferdig MT, Fernández Robledo JA, Fidock DA, Florent I, Fokou PV, Galstian A, Gamo FJ, Gokool S, Gold B, Golub T, Goldgof GM, Guha R, Guiguemde WA, Gural N, Guy RK, Hansen MA, Hanson KK, Hemphill A, Hooft van Huijsduijnen R, Horii T, Horrocks P, Hughes TB, Huston C, Igarashi I, Ingram-Sieber K, Itoe MA, Jadhav A, Naranuntarat Jensen A, Jensen LT, Jiang RH, Kaiser A, Keiser J, Ketas T, Kicka S, Kim S, Kirk K, Kumar VP, Kyle DE, Lafuente MJ, Landfear S, Lee N, Lee S, Lehane AM, Li F, Little D, Liu L, Llinás M, Loza MI, Lubar A, Lucantoni L, Lucet I, Maes L, Mancama D, Mansour NR, March S, McGowan S, Medina Vera I, Meister S, Mercer L, Mestres J, Mfopa AN, Misra RN, Moon S, Moore JP, Morais Rodrigues da Costa F, Müller J, Muriana A, Nakazawa Hewitt S, Nare B, Nathan C, Narraidoo N, Nawaratna S, Ojo KK, Ortiz D, Panic G, Papadatos G, Parapini S, Patra K, Pham N, Prats S, Plouffe DM, Poulsen SA, Pradhan A, Quevedo C, Quinn RJ, Rice CA, Abdo Rizk M, Ruecker A, St Onge R, Salgado Ferreira R, Samra J, Robinett NG, Schlecht U, Schmitt M, Silva Villela F, Silvestrini F, Sinden R, Smith DA, Soldati T, Spitzmüller A, Stamm SM, Sullivan DJ, Sullivan W, Suresh S, Suzuki BM, Suzuki Y, Swamidass SJ, Taramelli D, Tchokouaha LR, Theron A, Thomas D, Tonissen KF, Townson S, Tripathi AK, Trofimov V, Udenze KO, Ullah I, Vallieres C, Vigil E, Vinetz JM, Voong Vinh P, Vu H, Watanabe NA, Weatherby K, White PM, Wilks AF, Winzeler EA, Wojcik E, Wree M, Wu W, Yokoyama N, Zollo PH, Abla N, Blasco B, Burrows J, Laleu B, Leroy D, Spangenberg T, Wells T, Willis PA
PLoS pathogens   12(7) e1005763   Jul 2016   [Refereed]
Tuvshintulga B, AbouLaila M, Davaasuren B, Ishiyama A, Sivakumar T, Yokoyama N, Iwatsuki M, Otoguro K, Ōmura S, Igarashi I
Antimicrobial agents and chemotherapy   60(5) 2739-2746   May 2016   [Refereed]
Munkhjargal T, Ishizaki T, Guswanto A, Takemae H, Yokoyama N, Igarashi I
Veterinary parasitology   221 14-23   May 2016   [Refereed]
Zhou M, Cao S, Luo Y, Liu M, Wang G, Moumouni PF, Jirapattharasate C, Iguchi A, Vudriko P, Terkawi MA, Löwenstein M, Kern A, Nishikawa Y, Suzuki H, Igarashi I, Xuan X
Parasites & vectors   9 257   May 2016   [Refereed]
Omar MA, Salama A, Elsify A, Rizk MA, Al-Aboody MS, AbouLaila M, El-Sayed SA, Igarashi I
Experimental parasitology   161 62-67   Feb 2016   [Refereed]
Liyanagunawardena N, Sivakumar T, Kothalawala H, Silva SS, Battsetseg B, Lan DT, Inoue N, Igarashi I, Yokoyama N
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   37 64-69   Jan 2016   [Refereed]
Ichikawa-Seki M, Guswanto A, Allamanda P, Mariamah ES, Wibowo PE, Igarashi I, Nishikawa Y
Parasitology international   64(6) 484-486   Dec 2015   [Refereed]
Tuvshintulga B, Sivakumar T, Battsetseg B, Narantsatsaral SO, Enkhtaivan B, Battur B, Hayashida K, Okubo K, Ishizaki T, Inoue N, Igarashi I, Yokoyama N
Parasitology international   64(6) 527-532   Dec 2015   [Refereed]
Aboge GO, Cao S, Terkawi MA, Masatani T, Goo Y, AbouLaila M, Nishikawa Y, Igarashi I, Suzuki H, Xuan X
The Journal of parasitology   101(5) 536-541   Oct 2015   [Refereed]
Yokoyama N, Sivakumar T, Tuvshintulga B, Hayashida K, Igarashi I, Inoue N, Long PT, Lan DTB
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   30 288-295   Mar 2015   [Refereed]
Terkawi MA, Cao S, Herbas MS, Nishimura M, Li Y, Moumouni PF, Pyarokhil AH, Kondoh D, Kitamura N, Nishikawa Y, Kato K, Yokoyama N, Zhou J, Suzuki H, Igarashi I, Xuan X
Infection and immunity   83(1) 8-16   Jan 2015   [Refereed]
Elsify A, Sivakumar T, Nayel M, Salama A, Elkhtam A, Rizk M, Mosaab O, Sultan K, Elsayed S, Igarashi I, Yokoyama N
Parasitology international   64(1) 79-85   Feb 2015   [Refereed]
Jąkalski M, Wakaguri H, Kischka TG, Nishikawa Y, Kawazu S, Matsubayashi M, Kawahara F, Tsuji N, Cao S, Sunaga F, Xuan X, Okubo K, Igarashi I, Tuda J, Mongan AE, Eshita Y, Maeda R, Makałowski W, Suzuki Y, Yamagishi J
Nucleic acids research   43(Database issue) D631-6   Jan 2015   [Refereed]
Kengradomkij C, Inpankaew T, Kamyingkird K, Wongpanit K, Wongnakphet S, Mitchell TJ, Xuan X, Igarashi I, Jittapalapong S, Stich RW
Veterinary parasitology   207(1-2) 156-160   Jan 2015   [Refereed]
Yokoyama N, Sivakumar T, Fukushi S, Tattiyapong M, Tuvshintulga B, Kothalawala H, Silva SS, Igarashi I, Inoue N
Veterinary parasitology   207(3-4) 335-341   Jan 2015   [Refereed]
Rizk MA, El-Sayed SA, Terkawi MA, Youssef MA, El Said el Sel S, Elsayed G, El-Khodery S, El-Ashker M, Elsify A, Omar M, Salama A, Yokoyama N, Igarashi I
PloS one   10(4) e0125276   2015   [Refereed]
Asada M, Yahata K, Hakimi H, Yokoyama N, Igarashi I, Kaneko O, Suarez CE, Kawazu S
PloS one   10(5) e0125993   2015   [Refereed]
Chiou SP, Kitoh K, Igarashi I, Takashima Y
The Journal of veterinary medical science   76(9) 1281-1284   Sep 2014   [Refereed]
Cao S, Aboge GO, Terkawi MA, Zhou M, Kamyingkird K, Moumouni PF, Masatani T, Igarashi I, Nishikawa Y, Suzuki H, Xuan X
The Journal of parasitology   100(4) 522-526   Aug 2014   [Refereed]
Guswanto A, Sivakumar T, Rizk MA, Elsayed SA, Youssef MA, ElSaid Eel S, Yokoyama N, Igarashi I
Antimicrobial agents and chemotherapy   58(8) 4713-4717   Aug 2014   [Refereed]
AbouLaila M, Batadoj D, Salama A, Munkhjargal T, Ichikawa-Seki M, A Terkawi M, Yokoyama N, Igarashi I
Veterinary parasitology   204(3-4) 104-110   Aug 2014   [Refereed]
Yamagishi J, Wakaguri H, Yokoyama N, Yamashita R, Suzuki Y, Xuan X, Igarashi I
BMC genomics   15 678   Aug 2014   [Refereed]
Zhou M, Suganuma K, Ruttayaporn N, Nguyen TT, Yamasaki S, Igarashi I, Kawazu S, Suzuki Y, Inoue N
The Journal of veterinary medical science   76(6) 799-806   Jun 2014   [Refereed]
Inpankaew T, Jittapalapong S, Mitchell TJ, Sununta C, Igarashi I, Xuan X
Acta parasitologica   59(2) 305-309   Jun 2014   [Refereed]
Sivakumar T, Tattiyapong M, Okubo K, Suganuma K, Hayashida K, Igarashi I, Zakimi S, Matsumoto K, Inokuma H, Yokoyama N
Ticks and tick-borne diseases   5(3) 305-310   Apr 2014   [Refereed]
Wang M, Guo W, Igarashi I, Xuan X, Wang X, Xiang W, Jia H
The Journal of veterinary medical science   76(4) 549-552   Apr 2014   [Refereed]
Kamyingkird K, Cao S, Masatani T, Moumouni PF, Vudriko P, Mousa AA, Terkawi MA, Nishikawa Y, Igarashi I, Xuan X
The Journal of veterinary medical science   76(3) 323-330   Mar 2014   [Refereed]
Sivakumar T, Tattiyapong M, Fukushi S, Hayashida K, Kothalawala H, Silva SS, Vimalakumar SC, Kanagaratnam R, Meewewa AS, Suthaharan K, Puvirajan T, de Silva WK, Igarashi I, Yokoyama N
Veterinary parasitology   200(1-2) 24-30   Feb 2014   [Refereed]
Inpankaew T, Jiyipong T, Wongpanit K, Pinyopanuwat N, Chimnoi W, Kengradomkij C, Xuan X, Igarashi I, Xiao L, Jittapalapong S
Tropical animal health and production   46(2) 487-490   Feb 2014   [Refereed]
Tattiyapong M, Sivakumar T, Ybanez AP, Ybanez RH, Perez ZO, Guswanto A, Igarashi I, Yokoyama N
Parasitology international   63(1) 57-63   Feb 2014   [Refereed]
Salama AA, AbouLaila M, Terkawi MA, Mousa A, El-Sify A, Allaam M, Zaghawa A, Yokoyama N, Igarashi I
Parasitology research   113(1) 275-283   Jan 2014   [Refereed]
Salama AA, Terkawi MA, Kawai S, Aboulaila M, Nayel M, Mousa A, Zaghawa A, Yokoyama N, Igarashi I
Experimental parasitology   135(3) 623-628   Nov 2013   [Refereed]
Simking P, Saengow S, Bangphoomi K, Sarataphan N, Wongnarkpet S, Inpankaew T, Jittapalapong S, Munkhjargal T, Sivakumar T, Yokoyama N, Igarashi I
Veterinary parasitology   197(3-4) 642-648   Nov 2013   [Refereed]
Sivakumar T, Lan DT, Long PT, Yoshinari T, Tattiyapong M, Guswanto A, Okubo K, Igarashi I, Inoue N, Xuan X, Yokoyama N
The Journal of veterinary medical science   75(11) 1455-1462   Nov 2013   [Refereed]
Nagano D, Sivakumar T, De De Macedo AC, Inpankaew T, Alhassan A, Igarashi I, Yokoyama N
The Journal of veterinary medical science   75(11) 1463-1470   Nov 2013   [Refereed]
Sivakumar T, Okubo K, Igarashi I, de Silva WK, Kothalawala H, Silva SS, Vimalakumar SC, Meewewa AS, Yokoyama N
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   19 134-140   Oct 2013   [Refereed]
Cao S, Luo Y, Aboge GO, Terkawi MA, Masatani T, Suzuki H, Igarashi I, Nishikawa Y, Xuan X
Experimental parasitology   133 346-352   Mar 2013   [Refereed]
Munkhjargal T, Sivakumar T, Battsetseg B, Nyamjargal T, Aboulaila M, Purevtseren B, Bayarsaikhan D, Byambaa B, Terkawi MA, Yokoyama N, Igarashi I
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   16(2013) 178-185   Feb 2013   [Refereed]
Sivakumar T, Yoshinari T, Igarashi I, Kothalawala H, Abeyratne SA, Vimalakumar SC, Meewewa AS, Kuleswarakumar K, Chandrasiri AD, Yokoyama N
Ticks and tick-borne diseases   4(3) 235-241   Jan 2013   [Refereed]
Salama AA, Aboulaila M, Moussa AA, Nayel MA, El-Sify A, Terkawi MA, Hassan HY, Yokoyama N, Igarashi I
Veterinary parasitology   191(1-2) 1-10   Jan 2013   [Refereed]
Terkawi MA, Ratthanophart J, Salama A, AbouLaila M, Asada M, Ueno A, Alhasan H, Guswanto A, Masatani T, Yokoyama N, Nishikawa Y, Xuan X, Igarashi I
PloS one   8(12) e83305   2013   [Refereed]
Ueno A, Terkawi MA, Yokoyama M, Cao S, Aboge G, Aboulaila M, Nishikawa Y, Xuan X, Yokoyama N, Igarashi I
Parasitology international   62(2) 189-192   Dec 2012   [Refereed]
Kumar S, Yokoyama N, Kim JY, Bork-Mimm S, Inoue N, Xuan X, Igarashi I, Sugimoto C
Experimental parasitology   132 508-512   Dec 2012   [Refereed]
Yokoyama N, Sivakumar T, Ota N, Igarashi I, Nakamura Y, Yamashina H, Matsui S, Fukumoto N, Hata H, Kondo S, Oshiro M, Zakimi S, Kuroda Y, Kojima N, Matsumoto K, Inokuma H
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases   12 1669-1675   Dec 2012   [Refereed]
AbouLaila M, Terkawi MA, Seuseu FJ, Ota N, de Macedo AC, Yokoyama N, Xuan X, Igarashi I
Veterinary parasitology   190 401-410   Dec 2012   [Refereed]
Munkhjargal T, Aboulaila M, Ueno A, Sivakumar T, Nakano Y, Yokoyama M, Yokoyama N, Igarashi I
Veterinary parasitology   190 423-433   Dec 2012   [Refereed]
Hikosaka K, Tsuji N, Watanabe Y, Kishine H, Horii T, Igarashi I, Kita K, Tanabe K
BMC genomics   13 622   Nov 2012   [Refereed]
Cao S, Aboge GO, Terkawi MA, Zhou M, Luo Y, Yu L, Li Y, Goo Y, Kamyingkird K, Masatani T, Suzuki H, Igarashi I, Nishikawa Y, Xuan X
Parasitology international   62(2) 87-94   Nov 2012   [Refereed]
Chiou SP, Yokoyama N, Igarashi I, Kitoh K, Takashima Y
Experimental parasitology   132(3) 327-333   Nov 2012   [Refereed]
Sivakumar T, Kothalawala H, Abeyratne SA, Vimalakumar SC, Meewewa AS, Hadirampela DT, Puvirajan T, Sukumar S, Kuleswarakumar K, Chandrasiri AD, Igarashi I, Yokoyama N
Veterinary parasitology   190(1-2) 263-267   Nov 2012   [Refereed]
Yoshinari T, Sivakumar T, Asada M, Battsetseg B, Huang X, Lan DT, Inpankaew T, Ybañez AP, Alhassan A, Thekisoe OM, Macedo AC, Inokuma H, Igarashi I, Yokoyama N
The Journal of veterinary medical science / the Japanese Society of Veterinary Science      Oct 2012   [Refereed]
Munkhjargal T, AbouLaila M, Terkawi MA, Sivakumar T, Ichikawa M, Davaasuren B, Nyamjargal T, Yokoyama N, Igarashi I
The American journal of tropical medicine and hygiene   87(4) 681-688   Oct 2012   [Refereed]
Ooka H, Terkawi MA, Cao S, Aboge G, Goo YK, Luo Y, Li Y, Nishikawa Y, Igarashi I, Xuan X
The Journal of parasitology   98 1045-1048   Oct 2012   [Refereed]
Cao S, Aboge GO, Terkawi MA, Yu L, Kamyingkird K, Luo Y, Li Y, Goo YK, Yamagishi J, Nishikawa Y, Yokoyama N, Suzuki H, Igarashi I, Maeda R, Inpankaew T, Jittapalapong S, Xuan X
Parasitology research   111 1259-1266   Sep 2012   [Refereed]
Terkawi MA, Alhasan H, Ueno A, Ratthanophart J, Luo Y, Cao S, Kamyingkird K, Aboulaila M, Youn-Kyoung G, Nishikawa Y, Yokoyama N, Xuan X, Igarashi I
Parasitology international   61 493-496   Sep 2012   [Refereed]
Igarashi I, Makino T, Suzuki Y, Kai K, Teranishi M, Takasaki W, Furuhama K
The Journal of veterinary medical science / the Japanese Society of Veterinary Science      Sep 2012   [Refereed]
Islam MT, Igarashi I, Kawabuchi K
Bioscience trends   6(4) 165-175   Aug 2012   [Refereed]
Sivakumar T, Tagawa M, Yoshinari T, Ybañez AP, Igarashi I, Ikehara Y, Hata H, Kondo S, Matsumoto K, Inokuma H, Yokoyama N
Journal of clinical microbiology   50(6) 2111-2113   Jun 2012   [Refereed]
Aboulaila M, Munkhjargal T, Sivakumar T, Ueno A, Nakano Y, Yokoyama M, Yoshinari T, Nagano D, Katayama K, El-Bahy N, Yokoyama N, Igarashi I
Antimicrobial agents and chemotherapy   56(6) 3196-3206   Jun 2012   [Refereed]
Sivakumar T, Altangerel K, Battsetseg B, Battur B, Aboulaila M, Munkhjargal T, Yoshinari T, Yokoyama N, Igarashi I
Veterinary parasitology   187(1-2) 17-22   Jun 2012   [Refereed]
Terkawi MA, Alhasan H, Huyen NX, Sabagh A, Awier K, Cao S, Goo YK, Aboge G, Yokoyama N, Nishikawa Y, Kalb-Allouz AK, Tabbaa D, Igarashi I, Xuan X
Veterinary parasitology   187(1-2) 307-311   Jun 2012   [Refereed]
Altangerel K, Sivakumar T, Battsetseg B, Battur B, Ueno A, Igarashi I, Yokoyama N
Veterinary parasitology   184(2-4) 309-316   Mar 2012   [Refereed]
Galay RL, Maeda H, Aung KM, Umemiya-Shirafuji R, Xuan X, Igarashi I, Tsuji N, Tanaka T, Fujisaki K
Tropical animal health and production   44 343-348   Feb 2012   [Refereed]
Luo Y, Terkawi MA, Jia H, Aboge GO, Goo YK, Cao S, Li Y, Yu L, Ooka H, Kamyingkird K, Masatani T, Zhang S, Nishikawa Y, Igarashi I, Xuan X
Experimental parasitology   130(2) 178-182   Feb 2012   [Refereed]
Shimamoto Y, Sasaki M, Ikadai H, Ishizuka M, Yokoyama N, Igarashi I, Hoshi F, Kitamura H
The Journal of veterinary medical science / the Japanese Society of Veterinary Science   74(2) 241-245   Feb 2012   [Refereed]
Li Y, Terkawi MA, Nishikawa Y, Aboge GO, Luo Y, Ooka H, Goo YK, Yu L, Cao S, Sun Y, Yamagishi J, Masatani T, Yokoyama N, Igarashi I, Xuan X
Infection and immunity   80(1) 311-320   Jan 2012   [Refereed]
Terkawi MA, Thekisoe OM, Katsande C, Latif AA, Mans BJ, Matthee O, Mkize N, Mabogoane N, Marais F, Yokoyama N, Xuan X, Igarashi I
Veterinary parasitology   182(2-4) 337-342   Dec 2011   [Refereed]
Altangerel K, Battsetseg B, Battur B, Sivakumar T, Batmagnai E, Javkhlan G, Tuvshintulga B, Igarashi I, Matsumoto K, Inokuma H, Yokoyama N
Veterinary parasitology   182(2-4) 343-348   Dec 2011   [Refereed]
Altangerel K, Sivakumar T, Inpankaew T, Jittapalapong S, Terkawi MA, Ueno A, Xuan X, Igarashi I, Yokoyama N
The Journal of parasitology   97 1075-1079   Dec 2011   [Refereed]
Terkawi MA, Seuseu FJ, Eko-Wibowo P, Huyen NX, Minoda Y, AbouLaila M, Kawai S, Yokoyama N, Xuan X, Igarashi I
Molecular and biochemical parasitology   178(1-2) 40-45   Jul 2011   [Refereed]

Misc

 
Activities of National Research Center for Protozoan Diseases as OIE Reference Centres
Igarashi I.
Journal of the Japan Veterinary Medical Associatgion   65(11) 825-828   Nov 2012   [Invited]
Vet. Parasitol.   127:29-32.    2005
Int J Parasitol.   35:1031-1035.    2005
Inhibitory effect of lactoferrin on in vitro growth of Babebsia caballi.
Am J Trop Med Hyg   73:710-712.    2005
Antimicrob Agents Chemother.   (48) 236-341   2004
Improved enzyme-kinked immunosorbent assay using C-terminal truncated recombinant antigens of Basesai bovis rhoptry-associated protein-1 for detection of specific antibodies.
J Clin Microbiol.   (42) 1601-1604   2004
Tetsuya TANAKA, Yukie ABE, Noboru INOUE, Woan-Sub KIM, Haruto KUMURA, Hideyuki NAGASAWA, Ikuo IGARASHI, Kei-ichi SHIMAZAKI
J Vet Med Sci.   66(6) 619-625   2004
Growth inhibitory effect of triclosan on equine and bovine Babesia parasites
Am J. Trop. Med Hyg   68 334-340   2003
High-Level Expression and Purification of a Truncated Merozoite Antigen-2 of Babesia equi in Escherichia coli and Its Potential in Immunodiagnosis \.
J. Clin Microbiol.   41 1147-1151   2003
Clotrimazole, Ketoconazole, and Clodinafop-propargyl as Potent Growth Inhibitors of Equine Babesia Parasites during In vitro Cultures .
J. Parasitol.   89 604-606   2003
Antiviral Res.   60 193-199   2003
Morphological and populational characteristics of hemocytes of Ornithodoros moubata nymphs during the ecdysial phase.
J Med Entomol.   (40) 770-776   2003
Tetsuya TANAKA, Yukie ABE, Woan-Sub KIM, Xuenan XUAN, Hideyuki NAGASAWA, Ikuo IGARASHI, Haruto KUMURA, Kei-ichi SHIMAZAKI
J Vet Med Sci.   65(12) 1377-1380   2003
Development and evaluation of an enzyme-linked immunosorbent assay with recombinant SAG2 for diagnosis of Toxoplasma gondii infection in cats.
J. Parasitol.   88, 804-807    2002
Characterization of phagocytic hemocytes in Ornihodoros moubata (Acari: Ixodidae).
J. Med. Entomol.   38, 514-519    2001
Analysis of growth-promoting factor for Babesia caballi cultivation.
J. Parasitol.   87, 1484-1486    2001
International Journal of Parasitology   30 51-58   2000
Protein analysis of merozoites from in vitro cultured Babesia caballi by two-dimensional polyacrylamide gel electrophoresis and western blotting.
Journal of Veterinary Medical Science   62 323-327   2000
Morphological changes of ┣DBBabesia gibsoni(/)-┫DB grown in canine red blood cell-substituted sever combined immune deficiency mice.
J. Parasitol.   86 956-958   2000
Delivery of ┣DBNeospora caninum(/)-┫DB surface protein, NcSRS2(Nc-p43), to mouse using recombinant vaccinia virus.
Parasitol Res.   86 934-939   2000
Protozoan diseases in wild animals
Igarashi I.
53(11) 928-932   2000   [Invited]
Tublar structure associated with B. caballi-infected erythocytes in vitro.
Parasitology Research   85(3) 171-175   1999
Roles of CD4+ T cell and gamma interferon for protective immunity against Babesia microti infection in mice.
Infection and Immunity.   67 4143-4148   1999
Cloning and expression of a 48-kDa Babesia caballi merozoite rhoptry protein and potential use of the recombinant antigen in an Enzyme-linked Immunosorbent Assay.
Journal of Clinical Microbiology   37 3475-3480   1999
International Journal of Parasitology   29 1433-1436   1999
International Journal of Parasitology   29 1785-1791   1999
International Journal of Parasitology   26 1803-1808   1999
Non-invasive method of identification of SAG-1 transgenic mice by PCR analysis of oral wash cells.
Journal of Protozoology research   9 10-16   1999
Monoclonal antibody against Babesia equi : its characterization and potential use of antigen recognized by monoclonal antibodiy for diagnosis.
Journal of Clinical Micorbiology   36(7) 1835-1839   1998
Structural and immunochemical studies on bovine lactoferrin fragments.
Adv Exp Med Biol   443 41-48   1998
Experimental Parasitology   90(7) 290-293   1998
Diagnosis of Babesia caballi infection in horses by polymerase chain reaction.
Journal of Protozoology Research   8(2) 85-89   1998
The Journal of Veterinary Medical Science   59(6) 479-481   1997
Prevalence of equine piroplasmosis in Central Mongolia
Onderstepoort Journal of Veterinary Research   64 141-145   1997
Defferent activation of lymphocytes in reaction to ┣DBBabesia(/)-┫DB ┣DBmicroti(/)-┫DB infection in iNOS-/- and wildtype mice(共著)
Journal of Protozoology Research   7(2) 63-69   1997
Different activation of lymphocytes in reaction to Babesia microti infection in iNOS-/-and wildtype mice.
Journal of Protozoology Research   7(2) 63-69   1997
Purification of merozoites from in vitro cultured babesia cablli-infected equine eryhtrocytes.
Journal of Protozoology Research   7(4) 133-139   1997
Tetsuya TANAKA, Yoshitaka OMATA, Atsushi SAITO, Keiichi SHIMAZAKI, Ikuo IGARASHI, Naoyoshi SUZUKI
Journal of Veterinay Medical Science   58(1) 61-65   1996
Veterinary Parasitology   63 17-23   1996
Kei-ichi SHIMAZAKI, Myoung Soo NAM, Shinji HARAKAWA, Tetsuya TANAKA, Yoshitaka OMATA, Atsushi SAITO, Haruto KUMURA, Katsuhiko MIKAWA, Ikuo IGARASHI, Naoyoshi SUZUKI
Journal of Veterinary Medical Science   58(12) 1227-1229   1996
Detection of collagen-cross reactive anitigenic component in Toxoplasma gondii(共著)
Journal of Protozoology Research   5 33-39   1995
Toxoplasma gondii : Parasiticidal effects of bovine lactoferricin against parasites(共著)
Experimental Parasitology   81 614-617   1995
Role of heat shock protein in protecitve immunity aganst infection with Toxoplasma gondii(共著)
Bulletin de la Societe Franco-Japoneise des Sciences Veterinaires   6 154-162   1995
Correlation between antibody levels in ┣DBToxopalsma(/)-┫DB ┣DBgondii(/)-┫DB infected pigs and pathogenecity of the isolated parasite. (共著)
Veterinary Parasitology   51 205-210   1994
Yoshitaka OMATA, Shen-Zhi XU, Ikuo IGARASHI, Atsushi SAITO, Hideo TOBA, Naoyoshi SUZUKI
Journal of Veterinary Medical Science   56(3) 557-558   1994

Books etc

 
Tea in Health and Disease Prevention
Mahmoud AbouLaila, Igarashi I., (Part:Contributor, Green Tea and its Main Catechin, Epigallocatechin- 3-Gallate, Provide Parasitic Protection)
Elsevier   Oct 2012   
Drug Discovery in Infectious Diseases:Apicomplexan Parasites: Molecular Approaches toward Targeted Drug Development
Mohamad Alaa Terkawi,Igarashi I. (Part:Contributor, Drug discovery against Babesia and Toxoplasma (453-468))
Wiley-Blackwell   Feb 2011   
Asian Parasitology Vol. 4
(Ed. A. Saito, I. Igarashi) (Part:Contributor, bovine babesiosis, equine babesiosis, canine babesiosis, others)
AAA Committee   Mar 2005   
Progress in Clinical Parasitology. Vol 1.
Igarashi I. (Part:Contributor)
1989   
Babesiosis of Domestic Animals and Man(共著)
CRC Press   1988   
An Atlas of Renal Diseases in ┣DBAotus(/)-┫DB Monkeys with Experimental Plasmodial Infection(共著)
American Institute of Biological Sciences   1988   

Conference Activities & Talks

 
Diagnosisi for equine piroplasmosis.
I. Igarashi
International Workshop for south asian association for regional cooperation countries paraticipants on molecular diagnosis of equine piroplamosis   30 Nov 2012   National Research Center for Protozoan Diseases, Obihiro Univ., National Research Center for equine, India
Receent progress of of the diagnosis for equine piroplamosis
I. Igarashi
9th International Conference on equine infectious diseases   21 Oct 2012   
Genetic diversity of Theileria orientalis in tick vectors detected in Hokkaido, Japan
Igarashi I.
14 Sep 2012   
Epidemiology of bovine Babesia and Theileria parasites in Sri Lanka
Igarashi I.
14 Sep 2012   
Validating M17 leucine aminopeptidase of Babesia parasites as a molecular drug target
Igarashi I.
14 Sep 2012   
Apicoplast-targeting antibacterials inhibit the growth of Babesia parasites
M. Aboulaila et al, Igarashi I.
The first Regional Society for Tropical Veterinary Medicine: A change in global environment, biodiversity, diseases and health   18 Jun 2012   
Phylogenetic relationships of Mongolian Babesia bovis isolates based on merozoite surface antigen (MSA)-1, MSA-2b, and MSA-2c genes
Igarashi I.
27 Mar 2012   
PCR detection of Babesia ovata from cattle reared in Japan and clinical significance of co-infection with Theileria orientalis
Igarashi I.
27 Mar 2012   
Evaluation of a diagnostic PCR assay for the global detection of Babesia ovata in cattle
Igarashi I.
27 Mar 2012   
Cloning and characterization of histone deacetylase from Babesia bovis.
Tserendorji M.他4名Igarashi I.
23 Mar 2012   
Antibacterials target the apicoplast housekeeping machinery inhibited the growth of Babesia parasites
Aboulaila M. et al., Igarashi I.
23 Mar 2012   
Molecular characterization of a new Babesia bovis thrombospondin-related anonymous protein (BbTRAP2)
Igarashi I.
4 Nov 2011   
Development and evaluation Babesia bigemina-specific nested PCR method based on the gene encoding apical membrane antigen-1(AMA-1)
Igarashi I.
19 Sep 2011   
The first survey of Theileria orientalis infection in Mongolian cattle
Igarashi I.
19 Sep 2011   
Antifolates and their precursors target dihydrofolate reductase-thymidylates synthease of Babesia gibsoni and inhibit parasite proliferation
Igarashi I.
18 Jul 2011   
An improved immuchochromatographic test based on the C-terminal 48-kDa rhoptry protein for rapid detection of B. caballi infection in horses
Terkawi A.et al., Igarashi I.
18 Jul 2011   
Spherical body protein 4 is a new serological antigen for the global detection of Babesia bovis infection in cattle
Alaa Terkawi et al,Igarashi I.
45th Annual Japan-US Joint Conference on Parasitic Diseases   10 Jan 2011   
Molecular characterization of a new spherical body protein of Babesia bovis and evaluation of its potential use for serdiagnosis.
Igarashi I.
The XIIth International Congress of Parasitology   15 Aug 2010   
Development of a loop-mediated isothermal amplification method for rapid diagnosis of Babesia microti infection
Iseki Hiroshi et al., Igarashi I.
XXII Conference of the World Association for the Advancement of Veterinary Parasitology   8 Aug 2009   
Development of a Multiplex Loop- Mediated Isothermal Amplification (mLAMP) Method for Rapid Detection of Bovine Babesia parasites
Igarashi I.
The 2nd Thailand-Japan Joint Forum on Infectious Diseases   8 Oct 2008   
Application of the immunochromatographic test (ICT) for the diagnosis of tick-borne disease
Igarashi I.
VI International Conference on ticks and tick-borne pathogens   21 Sep 2008   
Development of an immunochromatographic test for the simultaneous serodiagnosis of bovine babesiosis
Igarashi I.
42th Annual Meeting of the US/Japan Parasitic Diseases Joint Panels   26 Jan 2008   
Development of loop-mediated isothermal amplification (LAMP) method for diagnosis of equine piroplasmosis
A.Alhassan et al., Igarashi I.
The Eleventh International Congress of Parasitology   6 Aug 2006   
Erythrocyte invasion by Babesia bovis via the host α2-3-linked sialic acid residues
Masashi Okamura, Naoaki Yokoyama, Noriyuki Takabatake, Yuzuru Ikehara, Ikuo Igarashi
14th Japanese-German Cooperative Symposium on Protozoan Diseases   20 Sep 2004   
Identification of Babesia bovis L-lactate dehydrogenase as a chemotherapeutical target against bovine babesiosis
Sabine Bork, Naoaki Yokoyama, Sutisak Boonchit, Masashi Okamura, Haruyuki Hirata, Ikuo Igarashi
14th Japanese-German Cooperative Symposium on Protozoan Diseases   20 Sep 2004   
Molecular diagnosis of equine babesiosis
Huang X, Xuan X, Yokoyama N, Igarashi I.
Obihiro International Symposium on strategies for research and control of tick- and tick-born diseases, in particular to tick-bioactive molecules (TBM) affecting transmission of tick-born diseases   2 Aug 2004   
Development of single-round and multiplex PCR method for the simultaneous detection of Babesia caballi and Babesia equi in horse blood
Alhassan A, Pumidonming W, Okamura M, Hirata H, Battsetseg B,Fujisaki K, Yokoyama N, Igarashi I
Obihiro International Symposium on strategies for research and control of tick- and tick-born diseases, in particular to tick-bioactive molecules (TBM) affecting transmission of tick-born diseases   2 Aug 2004   
Characterization of Babesia bovis L-lactate dehydrogenase and its applicability for the treatment of bovine babesiosis
Bork S, Yokoyama N, Boonchit S, Okamura M, Hirata H, Igarashi I.
Obihiro International Symposium on strategies for research and control of tick- and tick-born diseases, in particular to tick-bioactive molecules (TBM) affecting transmission of tick-born diseases   2 Aug 2004   
Essential role of the host sialic acids in erythrocyte invasion by Babesia bovis
Okamura M, Yokoyama N, Takabakake N, Ikehara Y, Igarashi I.
Obihiro International Symposium on strategies for research and control of tick- and tick-born diseases, in particular to tick-bioactive molecules (TBM) affecting transmission of tick-born diseases   2 Aug 2004   
Expression of Babesia equi EMA-1 and EMA-2 during merozoite developmental stages in erythrocytes and their interaction with erythrocytic membrane skelton
Kumar S, Yokoyama N, Kim JK, Huang X, Inoue N, Xuan X, Igarashi I, Sugimoto C
Obihiro International Symposium on strategies for research and control of tick- and tick-born diseases, in particular to tick-bioactive molecules (TBM) affecting transmission of tick-born diseases   2 Aug 2004   
Development of an ELISA using a recombinant Babesia bovis rhoptry associated protein 1 for the detection of specific antibodies in cattle
Boonchit S, Xuan X, Yokoyama N, Goff WL, Wagner G, Igarashi I.
The Second Congress of Federation of Asian Parasitologists   12 Nov 2003   
Growth inhibitory effect of heparin on Babesia parasites
Yokoyama N, Bork S, Igarashi I.
The Second Congress of Federation of Asian Parasitologists   12 Nov 2003   
Molecular diagnosis of babesiosis
Igarashi I, Huang X.
The Second Congress of Federation of Asian Parasitologists   12 Nov 2003   
Development and evaluation of an immunochromatographic test for rapid detection of Babesia equi infection in horses
Huang X, Xuan X, Yokoyama N, Suzuki N, Igarashi I.
The 11th international symposium of the world association of veterinary laboratory diagnosticians and OIE seminar on biothechnology   9 Nov 2003   
Molecular diagnosis in babesiosis
Igarashi I.
Forum Cheju-9: Parasitology Research Update   28 Oct 2003   
Detection of equine Babesia DNA in vector ticks.
Battsetseg B, Lucero S, Xuan X, Claveria FG, Inoue N, Byambaa B. Battur B, Boldbaatar D, Igarashi I, Nagasawa H, Mikami T, Fujisaki K.
13th Japanese-German Cooperative Symposium on Protozoan Diseases   2 Oct 2003   
Roles of Maltese cross form in the development of parasitemia and the protection against Babesia microti infection in mice
Yokoyama N,Bork S, Nishisaka M, Hirata H, Matsuo T, Inoue N, Xuan X, Suzuki H,Sugimoto C, Igarashi I.
13th Japanese-German Cooperative Symposium on Protozoan Diseases   2 Oct 2003   
Evaluation of antiprotozoan drugs,Clotrimazole, Ketoconazole and Clodinafop-propargyl, against equine Babesia parasites
Bork S, Yokoyama N,Matsuo T, Suzuki H,Nagasawa H,Fujisaki K,Sugimoto C, Igarashi I.
13th Japanese-German Cooperative Symposium on Protozoan Diseases   2 Oct 2003   
Glycophorin A is involved in the invasion of Babesia rodhaini into erythrocytes
Igarashi I, Takabatake N, Yokoyama N, Xuan X, Akimitsu N, Arimitsu N, Sekimizu K.
Tenth International Congress of Parasitology   4 Aug 2002   
Cloning of B. equi gene encoding 82-kDa protein and application for ELISA
Hirata H, Ikadai H, Yokoyama N, Xuan X, Inoue N, Nagasawa H, Fujisaki K, Suzuki N, Mikami T, Igarashi I.
XVIII Conference of the World Association for the Advancement of Veterinary Parasitology   26 Aug 2001   
Detection of antibodies to Babesia equi in horses by latex agglutination test using recombinant EMA-1.
Xuan X, Igarashi I, Tanaka T, Fukumoto S, Nagasawa H, Fujisaki, K., Mikami, T.
XVIII Conference of the World Association for the Advancement of Veterinary Parasitology   26 Aug 2001   
Identification and expression of a 50 kDa surfase antigen of Babesia gibsoni and its diagnostic potential in an enzme-linked immunosorbent assay
Fukumoto S, Xuan X, Nishikawa Y, Inoue N, Igarashi I, Nagasawa H, Fujisaki K, Mikami T.
Detection of antibodies to Babesia equi in horses by latex agglutination test using recombinant EMA-1.   26 Aug 2001   
Expression of Babesia equi merozoite antigen-1 in insect cells by recombinant baculovirus and evaluation of its daignostic use in ELISA
Xuan, X., Larsen, A., Ikadai, H., Tanaka, T., Igarashi, I., Nagasawa, H., Fujisaki, K., Toyoda, Y., Suzuki, N., and Mikami, T.
12th Japanese-German Cooperative Symposium on Protozoan Diseases   23 Sep 2000   
Babesia infection confirmed by in vitro cultivation in Mongolia
Igarashi, I., Xuan, X., Tanaka, T., Zayatiin , B., Gonchigoogiin, B., Nagasawa, H., Fujisaki, K., Mikami, T., Toyoda, Y. and Suzuki, N.
12th Japanese-German Cooperative Symposium on Protozoan Diseases   23 Sep 2000   
Diagnosis of Babesia caballi and Babesia equi infection in Dermacentor nuttali adult ticks.
Badgar, B., Xuan, X., Rodriguez, J.L., Badarch, B., Damdinsuren, B., Banzragch, B.,Gonchigoogin, B., Zayatiin, B., Ikadai, H., Igarashi, I., Nagasawa, H., Mikami, T. and Fujisaki, K.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Studies on the transovarial transmission of Babesia caballi and by the ixodid tick Haemaphysalis longicornis.
Rodriguez, J.L., Ikadai, H., Igarashi, I., Suzuki, N. and Fujisaki, K.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Ultrastructural changes of Babesia caballi in vitro culture caused by diminazen aceturate (Ganazeg).
Walter, S., Diamini, R.X., Jarabram, W., Fujisaki, K., Suzuki, N., Mikami, T. and Igarashi, I.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Cloning and expression of a 50 kDa Babesia gibsoni merozoite surface and potential use of the recombinant antigen in an enzyme-linked immunosorbent assay
Mugisha, J., Fukumoto, S., Xuan, X., Inoue, N., Igarashi, I., Nagasawa, H., Fujisaki, K., Suzuki, N. and Mikami, T.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Cloning and expression of a 58 kDa Babesia microti antigen
Nishisaka, M., Inoue, N., Xuan, X., Igarashi, I., Fujisaki, K., Nagasawa, H. and Mikami, T.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Morphological changes of Babesia gibsoni grown in canine red blood cell-substituted SCID mice.
Fukumoto, S., Xuan, X., Igarashi, I., Zhang, S., Mugisha, J., Ogata, T., Nagasawa, H., Fujisaki, K., Suzuki, N. and Mikami, T.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Continuous serum-free in vitro cultivation of Babesia caballi
Muinde, M.D., Ikadai, H., Igarashi, I., Suzuki, N. and Fujisaki, K.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Cloning and expression of an 18-kDa Babesia caballi merozoite rhoptry protein
Ikadai, H., Hirata, H., Xuan, X., Igarashi, I., Nagasawa, H., Fujisaki, K., Mikami, T., Suzuki, N. and Oyamada,
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Expression of Babesia equi merozoite antigen-2 by recombinant bacurovirus and its use in ELISA or Latex aggutination tes
Tanaka, T., Xuan, X., Inoue, N., Igarashi, I., Nagasawa, H., Fujisaki, K., Suzuki, N., Mikami, T. and Shimazaki, K.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Expression of Babesia equi merozoite antigen-1 in insect cells by recombinant baculovirus and evaluation of its diagnostic potential by ELISA.
Xuan, X., Larsen, A., Ikadai, H., tanaka, T., Igarashi, I., Nagasawa, H., Fujisaki, K., Toyoda, Y., Suzuki, N. and Mikami, T.
The 3rd Obihiro International Symposium on Strategies for Research and Control of Piroplasmosis   31 Aug 2000   
Cloning and expression of the 48 kDa Babesia caballi merozoite antigen and potential use of recombinant antigen for diagnosis.
Ikadai, H., Xuan, X., Igarashi, I., Nagasawa, H., Fujisaki, K., Toyoda, Y., Suzuki, N. and Mikami, T.
17th International Conference of the World Assocaition for the Advancement of Veterinary Parasitology   15 Aug 1999   
Induction of protection in mice by Babesia rodhaini antigen.
Igarashi, I., Asaba, U., Xuan, X., Nagasawa, H., Fujisaki, K., Suzuki, N. and Mikami, T.
17th International Conference of the World Association for the Advancement of Veterinary Parasitology   15 Aug 1999   
Mice deficient for TNF Receptor P55 are resistant to lethal infection with Babesia rodhaini.
Igarashi, I., Marbrlla C. O., Kamata, T., Omata, Y., Saito, A., Nagasawa, H., Fujisaki, K., Suzuki, N., Mak, T. and Toyoda, Y.
IXth International Congress of Parasitology   24 Aug 1998   
Monoclonal antibody against B. equi.
Avarzed, A., Igarashi, I., de Waal, T. D., Saito, A., Nagasawa, H., Toyoda Y. and Suzuki, N.
16th International Conference of the World Association for the Advancement of Veterinary Parasitology   10 Aug 1997   
Contribution of CD4 positive T-cells in control of Babesia microti infection
Igarashi, I., Waki, S., Omata, Y., Saito, A., Shinagawa, M. and Suzuki, N.
9th International Congress of Protozoology   25 Jul 1993   
Major role of CD4 positive T-cells in primary infection with Babesia microti in mice
Igarashi, I., Waki, S., Ito, M., Saito, A. and Suzuki, N.
13th Intern. Congress for Tropical Medicine and Malaria   29 Nov 1992   

Works

 
International molecular survey on babesiosis
Igarashi I.   Artistic Activity   Apr 1998 - Today
Establishment of in vitro culture of Babesia
The Others   1998 - Today
mechanisms of invasion and development of Babesia in erythrocytes
Igarashi I.   Artistic Activity   Apr 1997 - Today
Development of diagnostic methods for babesiosis
Igarashi I.   Artistic Activity   Apr 1995 - Today
Development of chemotherapy for babesiosis
Igarashi I.   Artistic Activity   Apr 1990 - Today

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2007 - 2010    Investigator(s): Ikuo IGARASHI
Babesiosis causes great economic losses to animal industry worldwide and designated as an exotic infectious disease. Objective of the present study was to develop new serological and molecular diagnostic tests against babesiaosis to do molecular e...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2007 - 2009    Investigator(s): Naoaki YOKOYAMA
Sialic acids and Heparan sulfate located on erythrocytes were demonstrated to play important roles as infectious receptors in the erythrocyte invasion by Babesia parasites. In contrast, several protozoan proteins were also identified as new protoz...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2006 - 2009    Investigator(s): Ikuo IGARASHI
Protozoan diseases such as babesiosis cause great economical losses to animal industry world-wide. Many amimals are imported from foreign countries to Japan every year, and it is important to prevent invasion of infected these animals to Japan at ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2005 - 2008    Investigator(s): Xuenan XUAN
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2001 - 2004    Investigator(s): Ikuo IGARASHI
Equine babesiosis, caused by Babesia equi and Babesia caballi, is characterized by fever, anemia, icterus, hepatosplenomegaly, lethargy, and, in some cases, leading to great economic losses in the horse industry. The infected horses often remain c...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2001 - 2003    Investigator(s): 見上 彪, Xuenan XUAN
1)Cloning of genes encoding immunodominant antigens of protozoan parasitesIn the present study, many genes encoding irnmunodominat antigens of protozoan parasites were identified, cloned and characterized. The main genes are as follows : B.caballi...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2000 - 2002    Investigator(s): Kozo FUJISAKI
(1) in vitro experimental culture system of Theileria orientalis sergenti has been established and it has been demonstrated that this system might be very useful for studies of parasite penetration of or liberation from red blood cells, proliferat...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2000 - 2002    Investigator(s): Kozo FUJISAKI
(1) Serum samples from horses in the States of Sao Paulo and Mato Grosso do Sul, Brazil were examined for diagnosis of equine piroplasmosis by both the latex agglutination test (LAT) and the enzyme-linked immunosorbent assay (ELIZA) with recombina...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 1999 - 2002    Investigator(s): Takeshi MIKAMI
1) Cloning and expression of feline IL-12 geneIt is known that IL-12 enhances NK activity, stimulates CTL activity and induces INF-γ production, and therefore IL-12 is considered as a key cytokine in Th1 helper cell-derived immune responses. A ful...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 1999 - 2002    Investigator(s): Takeshi MIKAMI
1) Development of animal herpesvirus vectorsIn the present study, some virulent and non-essential genes, such as TK, gE and gI genes of herpesviruses were identified and cloned. Herpesviruses deleting these genes can grow in vitro, however their v...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2001    Investigator(s): Ikuo IGARASHI
Babesiosis in domestic animals causes enormous economic losses throughout most of the world. In Mongolia, high prevalence of babesiosis was observed in horses but not known in cattle. In the present study, in vitro cultivation was used for isolati...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2001    Investigator(s): Hideyuki NAGASAWA
Protozoan parasites are most important causative of infectious diseases in the world. The subjectives of this study have focused on the prevention of protozoan diseases through the studies on biological substances and products derived from protozo...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2001    Investigator(s): Kozo FUJISAKI
(1) Enzyme-linked immunosorbent assay (ELISA), latex agglutination tests, and Western blot using recombinant proteins (EMA-1 and GST-BC48) have been established and their high sensitivity and specificity for antibody detection have been demonstrat...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1998 - 2001    Investigator(s): Chihiro SUGIMOTO
During the course of Theileria orientalis infection in cattle, parasite population bearing different major piroplasm surface protein (MPSP) genes appear by turns, which may be one of immune evasion mechanisms of the parasite. Therefore, analysis o...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1998 - 2000    Investigator(s): Xuenan XUAN
In host-parasite interaction, the surface proteins of both host and parasite cells play an important role and the surface antigens of the parasites are therefore logical targets for subunit vaccine development. Several surface antigens, such as P1...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1997 - 2000    Investigator(s): Ikuo IGARASHI
1. Babesia microti produces a self-limiting infection in mice, and recovered mice are resistant to reinfection. In the present study, the protective mechanisms against B.microti were examined using macrophage scavenger receptor (SR), inducible nit...
Studies on receptor and ligand on Babesia
Grant-in-Aid for Scientific Research
Project Year: 1999   
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(A), 基盤研究(A))
Project Year: 1995 - 1998    Investigator(s): Atsushi SAITO
(1) Studies on newly synthesized peptidesNewly synthesized peptide (Obioactin to Obiopeptides) of the activity units which were isolated from cytokines as an immunoregulator were examined in the effect of Toxoplasma chronically infected animals. M...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 1996 - 1997    Investigator(s): Yutaka TOYODA
(l)Studies on gene knock-out miceExperiments on the host defense mechanisms against protozoan infection were performed using a macrophage scavenger receptor (SR) knock-out mice. As the SR is known to bind an extraordinary wide range of ligands inc...
In vitro cultivation of Babesia parasites and it's application for diagnosis
Grant-in-Aid for Scientific Research
Project Year: 1997   
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(試験研究(B), 基盤研究(A))
Project Year: 1994 - 1996    Investigator(s): Naoyoshi SUZUKI
Newly synthesized peptide (Obioactin to Obiopeptides) of the activity units which were isolated from cytokines (lymphokines) as an immunoregulator were examined in the effect of Toxoplasma chronically infected animals. Mice chronically infected wi...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(C))
Project Year: 1994 - 1995    Investigator(s): Ikuo IGARASHI
Babesiosis in cattle and equine is endemic and causes enormous economic losses throughout most of the tropical and subtropical regions of the world. In this study, establishment of continuous cultivation of bovine and equine Babesia parasites were...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(A))
Project Year: 1991 - 1994    Investigator(s): Naoyoshi SUZUKI
An imunomodulator, such as TLA (Toxoplasma lysate antigens) was tested in the experiments. Growth of the tumor autoinduced by 20-methylcholanthrene (MC) in rats and mice was inhibited after intramuscular injection of TLA.The antitumor activity of ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(C))
Project Year: 1991 - 1993    Investigator(s): Ikuo IGARASHI
Role of cell-mediated immunity in Babesia infection was investigated using mouse models in the present study. In lethal Babesia rodhaini infection, drug-cured mice showed 75% protection against challenge infection with B.rodhaini and a humoral imm...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(試験研究(B))
Project Year: 1991 - 1993    Investigator(s): Naoyoshi SUZUKI
Using newly synthesized peptides on the activity units which were isolated from lymphokines as an immunoregulator, Obiopeptide, the effect of immunosuppression caused by cyclophosphamide to animals cronically infected with Toxoplasma gondii was ex...
Immunological Studies on Hemoprotozoan Diseases
Grant-in-Aid for Scientific Research
Project Year: 1991   
Development of serodiagnostic tests for protozoan infections

Patents

 
鈴木 寛, 長澤 秀行, 五十嵐 郁男, 五十嵐 慎, 田中 一郎, 鈴木 直義
藤崎 幸蔵, 長澤 秀行, 五十嵐 郁男, 鈴木 宏志, 杉本 千尋, 玄 学南, ユウ ミョンジョ, 辻 尚利
藤崎 幸蔵, 長澤 秀行, 五十嵐 郁男, 鈴木 宏志, 杉本 千尋, 玄 学南, 門田 君江, 井上 昇, 横山 直明, 辻 尚利
藤崎 幸蔵, 長澤 秀行, 五十嵐 郁男, 鈴木 宏志, 杉本 千尋, 玄 学南, 門田 君江, 井上 昇, 横山 直明, 辻 尚利
藤崎 幸蔵, 長澤 秀行, 五十嵐 郁男, 鈴木 宏志, 杉本 千尋, 玄 学南, ユウ ミョンジョ, 辻 尚利
藤崎 幸蔵, 福本 晋也, 玄 学南, 五十嵐 郁男, 長澤 秀行, 見上 彪, 種子野 章, 野中 富士男
鈴木 直義, 藤崎 幸蔵, 見上 彪, 長澤 秀行, 五十嵐 郁男, 玄 学南, 神尾 次彦, 辻 尚利, ユウ・ミンジョ
GENE ENCODING MEROZOITE PROTEIN OF BABESIA CABALLI, RECOMBINANT PROTEIN OBTAINED THEREFORM AND UTILIZATION THEREOF
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