佐藤公彦 (Kimihiko Satoh) - マイポータル - researchmap

基本情報

所属: 弘前大学大学院保健学研究科生体機能科学分野教授

学位: 理学博士(東京大学)
理学修士(東北大学)

J-GLOBAL ID: 200901026779900352
researchmap会員ID: 1000002901

研究キーワード

5

研究分野

2

委員歴

1

2001年

日本生化学会, 評議員

MISC

20

Enzymatic detection of precursor cells of preneoplastic foci positive for γ-glutamyltranspeptidase in rat liver.

Int. J. Cancer 115(5) 711-716 2005年7月
Kimihiko Satoh and Hatayama I. Anomalous elevation of glutathione S-transferase P-form (GST-P) in the elementary process of epigenetic initiation of chemical hepatocarcinogenesis in rats.

Carcinogenesisís 23(7), 1193-1198 2002年
A 1-Hour ELISA for quantitation of a crolein and hydroxynonenal-modified proteins by epitope-bound casein matrix method

Anal. Biochem. 270(2) 323-328 1999年
Weak electrophile selective characteristics of the rat preneoplastic marker enzyme glutathione S-transferase P-form, GST-P (7-7): a theory of linear free energy relationships for evaluation of the active site hydrophobicity of isoenzymes

K Satoh

CARCINOGENESIS 19(9) 1665-1671 1998年9月
Oxidative stress response in iron-induced renal carcinogenesis : Acute nephrotoxicity mediates the enhanced expression of glutathione S-transferase Yp isozyme.

Arch. Biochem. Biophys. 329(1) 39-46 1996年
THE HIGH NONENZYMATIC CONJUGATION RATES OF SOME GLUTATHIONE-S-TRANSFERASE (GST) SUBSTRATES AT HIGH GLUTATHIONE CONCENTRATIONS

K SATOH

CARCINOGENESIS 16(4) 869-874 1995年4月
LACK OF CORRELATED EXPRESSION BETWEEN THE GLUTATHIONE-S-TRANSFERASE P-FORM AND THE ONCOGENE PRODUCTS C-JUN AND C-FOS IN RAT-TISSUES AND PRENEOPLASTIC HEPATIC FOCI

S SUZUKI, K SATOH, H NAKANO, HATAYAMA, I, K SATO, S TSUCHIDA

CARCINOGENESIS 16(3) 567-571 1995年3月
C-JUN EXPRESSION IN SINGLE CELLS AND PRENEOPLASTIC FOCI INDUCED BY DIETHYLNITROSAMINE IN B6C3F1 MICE - COMPARISON WITH THE EXPRESSION OF PI-CLASS GLUTATHIONE-S-TRANSFERASE

H NAKANO, HATAYAMA, I, K SATOH, S SUZUKI, K SATO, S TSUCHIDA

CARCINOGENESIS 15(9) 1853-1857 1994年9月
LOSS OF PEROXISOMAL ENZYME EXPRESSION IN PRENEOPLASTIC AND NEOPLASTIC LESIONS INDUCED BY PEROXISOME PROLIFERATORS IN RAT LIVERS

Y YOKOYAMA, S TSUCHIDA, HATAYAMA, I, K SATOH, T NARITA, MS RAO, JK REDDY, J YAMADA, T SUGA, K SATO

CARCINOGENESIS 13(2) 265-269 1992年2月
TRANSIENT INDUCTION OF SINGLE GST-P POSITIVE HEPATOCYTES BY DEN

K SATOH, HATAYAMA, I, N TATEOKA, K TAMAI, T SHIMIZU, M TATEMATSU, N ITO, K SATO

CARCINOGENESIS 10(11) 2107-2111 1989年11月
The subunit structure of a major glutathione S-transferase form, Mt, in rat testis.

Eur. J. Biochem. 176(3) 551-557 1988年
Stable phenotypic expression of glutathione S-transferase placental form and unstable phenotypic expression of γ-glutamyltransferase in rat liver preneoplastic and neoplastic lesions.

Carcinogenesis 9(2) 215-220 1988年
PURIFICATION OF A NEW ACIDIC GLUTATHIONE S-TRANSFERASE, GST-YN1 YN1, WITH A HIGH LEUKOTRIENE-C4 SYNTHASE ACTIVITY FROM RAT-BRAIN

S TSUCHIDA, T IZUMI, T SHIMIZU, T ISHIKAWA, HATAYAMA, I, K SATOH, K SATO

EUROPEAN JOURNAL OF BIOCHEMISTRY 170(1-2) 159-164 1987年12月
SINGLE GST-P POSITIVE LIVER-CELLS - PUTATIVE INITIATED HEPATOCYTES

MA MOORE, K NAKAGAWA, K SATOH, T ISHIKAWA, K SATO

CARCINOGENESIS 8(3) 483-486 1987年3月
Relative merits of immunohistochemical demonstrations of placental, A, B, and C forms of glutathione S-transferase as markers of altered cell foci during liver carcinogenesis.

Carcinogenesis 6 1621-1626 1987年
CHANGES IN MOLECULAR-FORMS OF RAT HEPATIC GLUTATHIONE S-TRANSFERASE DURING CHEMICAL HEPATOCARCINOGENESIS

A KITAHARA, K SATOH, K NISHIMURA, T ISHIKAWA, K RUIKE, K SATO, H TSUDA, N ITO

CANCER RESEARCH 44(6) 2698-2703 1984年
Characterization of nucleolar antigens of normal rat liver, regenerating liver, and Novikoff hepatoma cells following in vitro translation of poly A mRNA

Cancer Research 43 1983年
Isozyme patterns of glycogen phosphorylase in rat lissues and transplantable hepatomas.

Cancer Research. 36 487-495 1976年
Ion-exchange chromatography of a dineleotide preparation from controlled alkaline hydrolysis of ribovncleic acids

Biochemical Journal 114 1969年
Optical rotatory dispersion of five homodinucleotides.

Yasuo Inoue, Kimihiko Satoh

Biochemical Journal 113 843-851 1969年

所属学協会

3

Works(作品等)

2

発癌性アルデヒドの免疫化学的迅速検出法の開発

1998年 - 1999年
Development of a rapid immunochemical method for quantitation of carcinogeneic aldehydes

1998年 - 1999年

共同研究・競争的資金等の研究課題

4

Investigation of molecular and cellular processes of initiation of rat chemical hepatocarcinogenesis

Basic Research Promotion Service for Health and Medical Field 1983年 - 2010年
ラット肝前癌マーカー酵素グルタチオン S-トランスフェラーゼP型(GST-P)の特異機能の解明

保健医療分野における基礎研究推進事業
ラット肝発癌イニシエーションの分子機構の解析

保健医療分野における基礎研究推進事業
Functional analysis of rat preneoplastic marker enzyme glutathione S-transferase P-form, GST-P

Basic Research Promotion Service for Health and Medical Field

産業財産権

2