J-GLOBAL         Last updated: Jun 8, 2019 at 03:31
Iwate University
(BLANK), Doctor of Agriculture

Research Interests


Research Areas

  • Agricultural chemistry / Food science / Nutiritional Chemistry

Academic & Professional Experience

Miyazaki University, Associate Professor
The University of British Columbia, Research Associate
- Iwate University, Associate Professor


Apr 1974
Mar 1977
Tokyo Noko University
Graduate School, Division of Agricultural Science, The University of Tokyo
Faculty of Agriculture, Tokyo University of Agriculture and Technology

Published Papers

In vitro and in vivo inhibition of muscle lipid and protein oxidation by carnosine.
Takashi NAGASAWA, Tatsuji YONEKURA, Naoyuki NISHIZAWA, and David D. KITTS
Mol. Cell. Biochem.   225(1/2) 29-34   Jan 2001
Effect of insulin, amino acids and fasting on myofibrillar protein degradation in perfused hindquaters of rats(共著)
Journal of Nutritional Science and Vitaminology   31 431-440   Jan 1985   [Refereed]
Nutritional and biochemical studies on muscle protein degradation
T. Nagasawa
Journal of Japanese Sosiety of Nutrition and Food Science   48(5) 347   Jan 1995   [Refereed]
Polypeptide compositions and NH2-terminal amino acid sequences of proteins in foxtail and proso millets
Bioscience, Biotechnology and Biochemistry   63(11) 1921-1926   Jan 1999
Effects of dietary Korean proso-millet protein on plasma adiponectin, HDL cholesterol, insulin levels and gene expression in obese type2 diabetic mice
72(11) 2918-2925   Nov 2008   [Refereed]
Measurement of the rate of myofibrillar protein degradation using the ateriovenous difference in plasma 3-methylhistidine concentration of rats
55(4) 381-384   Aug 2009   [Refereed]
53(5) 1-6   May 2011
Effects of dietary protein of Korean foxtail millet on plasma adiponectin, HDL-cholesterol, and insulin levels in genetically type 2 diabetic mice(共著)
69 31-37   Jan 2005   [Refereed]
Oxidative stress induces phosphoenolpyruvate carboxykinase expression in H4IIE cells(共著)
70(9) 2191-2198   Sep 2006   [Refereed]
Tissue specific regulation of 4E-BP1 and S6K1 phosphorylation by a-ketoisocaproate
Yoshizawa,F., Sekizawa,H., Hirayama,S., Yamazaki, Y., Nagasawa, T., Sucahara,K.
50 56-60   Jan 2004   [Refereed]
Effects of dietary protein of Korean foxtail millet on plasma adiponectin, HDL-cholesterol, and insulin levels in genetically type 2 diabetic mice. (共著)
69 31-37   Jan 2005   [Refereed]
Quantitative determination of urinary Nτ-methlyhistidine output as an index of myofibrillar protein degradation(共著)
Journal of Biochemistry   89 1155-1161   Jan 1981   [Refereed]
Simple and sensitive determination of plasma Nτ-methylhistidine by high performance liquid chromatography using pre-column derivative formation(共著)
Journal of Chromatography   (566) 223   Jan 1991
Casein phosphopeptides enhance paracellular calcium absorption but do not alter temporal blood pressure in normotensive rats. (共著)
Nutrition Research   (11) 819   Jan 1991
In vitro metabolism of chitin and protein from ruminal fungi by ruminal protozoa (共著)
Animal Science and Technology   64(6) 584-592   Jan 1993
Chiral high-performance liquid chromatographic separation of the three stereoisomers of 2,6-diaminopimelic acid without derivatisation (共著)
Journal of Chromatography   (A653) 336-340   Jan 1993
High molecular weight protease in rumen ciliate protozoa(共著)
Bioscience, Biotechnology and Biochemistry   58(11) 2020   Jan 1994
Ileal absorption of calcium and effect on blood pressure parameters in rats fed dairy constituents(共著)
Milchwissenschaft   45(6) 348   Jan 1990
Plasma Nτ-methylhistidine concentration in a sensitive index of myofibrillar protein degradation during starvation in rats
Bioscience,Biotechnology and Biochemstry   60(3) 501   Jan 1996
Effects of Dietary vitamin B6 and protein levels on growth teed efficiency GOT activity and muscle protein accumulation in young broiler chicks
Bulletin of the Faculty Agriculture,Miyazaki University   42(1・2) 31   Jan 1996
Protein synthesis and degradation change rapidly in response to food intake in muscle of food-deprived mice
Yoshizawa,F., Nagasawa,T., Funabiki,R., Nishizawa,N.
The Journal of Nutrition   127(6) 1156   Jan 1997
Reduction of muscle protein degradation by dietary protein after food intake
Reports of The Research Committee of Essential Amino Acids(Japan)   (151) 4   Jan 1998
Oxidative modification of skeletal muscle proteins in rats fed vitamin E deficient diet
Reports ot The Research Committee of Essential Amino Acids(Japan)   (149) 58   Jan 1997
Dietary supplement of G-rutin reduces oxidative damage in the rodent model
Journal of Agricultural and Food Chemistry   47(3) 1078   Jan 1999
Enhancing effect of dietary vinegar on the intestinal absorption of calcium ovariectomized rats
Bioscience, Biotechnology and Biochemistry   63(5) 905   Jan 1999
Rapid suppression of protein degradation in skeletal muscle after oral feeding of leucine.
Takashi NAGASAWA, Taketoshi KIDO, Fumiaki YOSHIZAWA, Yoshizaki ITO, and Naoyuki NISHIAZWA
J. Nutr. Biochem.   13(2) 121-127   Jan 2002
Effects of dietary protein of proso millet on liver injury induced by D-galactosamine in rats.
Naoyuki NISHIZAWA, Daiki SATO, Yoshizaki ITO, Takashi NAGASAWA, Yasuko HATAKEYAMA, Myeong-Rak CHOI, You-Young CHOI, and Yi Min WEI
Biosci. Biotechnol. Biochem.   66(1) 92-96   Jan 2002
Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats. 47: 311-315
J. Nutr. Sci. Vitaminol.   47(4) 311-315   Jan 2001
Inhibition of glycation reaction in tissue protein incubations by water soluble rutin derivative
Takashi NAGASAWA, Nobuaki TABATA, Yoshiaki ITO, Naoyuki NISHIZAWA, Youich AIBA, David D. KITTS
Mol. Cell. Biochem.   249 3-10   Jan 2003
Isolation and characterization of a 41 kDa sericin from the wild silkmoth Antheraea yamamai
78(1) 11-16   Jan 2009   [Refereed]
Contents of free D-Ala and D-Glu in traditional Asian fermented seasonings (共著)
56(6) 428-436   Dec 2010   [Refereed]
An antioxidative nutrient-rich enteral diet attenuates lethal activity and oxidative stress induced by lipopolysaccharide in mice(共著)
31(3) 181-187   May 2007   [Refereed]
Dietary G-rutin suppresses glycation in tissue proteins of streptozotocin-induced diabetic rats
Takashi NAGASAWA, Nobuaki TABATA, Yoshiaki ITO, Naoyuki NISHIZAWA, Youich AIBA, David D. KITTS
Mol. Cell. Biochem.   252 141-147   Jan 2003
Myofibrillar protein catabolism is rapidly suppressed following protein feeding
Bioscience, Biotechnology and Biochemistry   62(10) 1932   Jan 1998
Plasma HDL subfraction levels increasse in rats fed proso-millet protein concentrate(共著)
12(7) BR221-BR226   Jul 2006   [Refereed]
Chemistry and genotoxicity of caramelized sucrose(共著)
50 1180-1190   Dec 2006   [Refereed]
Galactosyllactoses in the milk of Japanese women: Changes in concentration during the course of lactation. (共著)
51 341-344   Jun 2004   [Refereed]
Suppression of myofibrillar protein degradation after refeeding in young and adult mice
Nagasawa,T., Kikuchi,N., Ito,Y., Yoshizawa,F., Nishizawa,N.
50 227-230   Jan 2004   [Refereed]
Influence of the amount of boiling water on the sensory evaluation, oxalic acid and potassium content of boiled spinach.
Izumi M, Takaya M, Nagasawa T
38(4) 343-349   Aug 2005   [Refereed]
Supplementation with dietary leucine to a protein-deficient diet suppreses myofibrillar protein degradation in rats(共著)
53(6) 552-555   Dec 2007   [Refereed]
The effect of insulin on myofibrillar protein degradation in normal and streptozotocin-induced diabetic rats measured by the rate of Nτ-methlyhistidine(共著)
Agricaltural Biological Chemistry   46 3023-3027   Jan 1982   [Refereed]
The effect of protease inhibitor on tyrosine and Nτ-methylhistidine release from incubated diaphragm (jointly worked)
Journal of Japanese Society of Nutrition and Food Science   37(4) 366-368   Jan 1984   [Refereed]
Paracellular calcium absorption, femur mineralization and biomechanics in rats fed selected dietary proteins(共著)
Food Chemistry   (39) 125   Jan 1991
Simple, rapid and sensitive determination of plasma taurine by high-performance liquird chromatography using pre-column derivative(共著)
Journal of Chromatography   (576) 155   Jan 1992
Exopeptidase activity of mixed rumen ciliate protozoa(共著)
Animal Science and Technology   63(5) 481   Jan 1992
A new intracellular proteolytic activity in mixed rumen ciliate protozoa(共著)
Asian-Australasian Journal of Animal Science   2(3) 446   Jan 1989
Effect of casein, casein phosphopeptides and calcium intake or ileal 45Ca disappearance and temporal systolic blood pressure in spontaneously hypertensive rat. (共著)
British Journal of Nutrition   68(3) 765   Jan 1992
Effect of starvation on the plasma Nτ-methylhistidine concentration in goats. (共著)
Bioscience, Biotechnology and Biochemistry   57(3) 517   Jan 1993
In vitro metabolism of tryptophan by rumen microorganisms : The interrelationship between mixed rumen protozoa and bacteria (共著)
Animal Science and Technology   64(11) 1079-1086   Jan 1993
Effects of salinomycin on the production of tryptophan, skatole and their related compounds by rumen bacteria , protozoa and their mixture (共著)
Animal Science and Technology   64(11) 1087-1093   Jan 1993


Simple and sensitive determination of plasma Nτ-methylhistidine by high performance liquid chromatography using pre-column derivative formation(共著)
Journal of Chromatography   566,223    1991
Quantitative determination of urinary Nτ-methlyhistidine output as an index of myofibrillar protein degradation(共著)
Journal of Biochemistry   89,1155    1981

Books etc

Apr 2007   ISBN:978-4-7827-05
Methods of Protein Metabolism
Gakkai Shuppan Senter Co. Ltd   Dec 2000   ISBN:4-7622-2962-8
Basic Nutrtion
Ishiyaku Publishers, Inc.   Nov 2005   ISBN:4263704762
Molecular Nutrition
Kagakudoujin Co. Ltd   Nov 2005   ISBN:4-7598-1214-8
Apr 2008   ISBN:9784782705490

Conference Activities & Talks


Research Grants & Projects

Regulation Mechanism of Muscle Protein Synthesis and Degradation
Suppression of oxidative stress and glycation by food
Effect of free radicals on protein metabolism