WADA Hiroshi Last updated: Aug 29, 2018 at 11:00
Academic & Professional Experience
2013
-
Today
Professor, Department of Intelligent Information Systems
2008
-
2012
Chair, Department of Mechanical and Aerospace Engineering, Graduate School of Engineering, Tohoku University
1988
-
1993
Tohoku University, Associate Professor
1993
- Professor, Faculty of Engineering, Tohoku University
1985
-
1987
Tohoku University, Lecturer
Education
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1977
Graduate School, Division of Engineering, Tohoku University
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1972
Faculty of Engineering, Tohoku University
Committee Memberships
1998
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2006
International Society of Audiology A member of the Committee of the International Society of Audiology
Published Papers
Aithal V, Kei J, Driscoll C, Murakoshi M, Wada H
Journal of the American Academy of Audiology 29 106-117 2018 [Refereed]
Aithal V, Kei J, Driscoll C, Murakoshi M, Wada H
International Journal of Audiology 56(3) 154-163 Mar 2017 [Refereed]
Murakoshi M, Sano K, Kanka N, Yoshida N, Hamanishi S, Kiyokawa H, Kakuta R, Aithale S, Aithale V, Kei J, Driscoll C, Swanston A, Matsutani S, Kobayashi K, Wada H
Procedia IUTAM 24 5-14 2017 [Refereed]
Murakoshi M, Takeda S , Wada H
Journal of Biomechanical Science and Engineering 12 2017 [Refereed]
Nabeyama W, Ishihara K, Ban HS, Wada H, Nakamura H
Bioorganic & Medical Chemistry 25 2601-2608 2017 [Refereed]
Aithal V, Kei J, Driscoll C, Murakoshi M, Wada H
International journal of pediatric otorhinolaryngology 82 64-72 Mar 2016 [Refereed]
Aithal V, Kei J, Driscoll C, Swanston A, Murakoshi M, Wada H
International journal of pediatric otorhinolaryngology 79(7) 1024-1029 Jul 2015 [Refereed]
Murakoshi M, Suzuki S, Wada H
BioMed research international 2015 727434 2015 [Refereed]
Aithal V, Kei J, Driscoll C, Swanston A, Roberts K, Murakoshi M, Wada H
Journal of the American Academy of Audiology 25(4) 343-354 Apr 2014 [Refereed]
Michio Murakoshi, Naoto Yoshida, Mitsuki Sugaya, Yudai Ogawa, Shinji Hamanishi, Hiromichi Kiyokawa, Risako Kakuta, Masaaki Yamada, Ritsuko Takahashi, Shingo Tanigawara, Sachiko Matsutani, Toshimitsu Kobayashi, Hiroshi Wada
International Journal of Pediatric Otorhinolaryngology 77(4) 504-512 2013
Elena V. Surovtseva, Alexander H. Johnston, Weikai Zhang, Ya Zhang, Adele Kim, Michio Murakoshi, Hiroshi Wada, Tracey A. Newman, Jing Zou, Ilmari Pyykko
International Journal of Pharmaceutics 424(1-2) 121-127 2012
Takatoshi Inaoka, Hirofumi Shintaku, Takayuki Nakagawa, Satoyuki Kawano, Hideaki Ogita, Tatsunori Sakamoto, Shinji Hamanishi, Hiroshi Wada, and Juichi Ito
Proc Natl Acad Sci USA 108(45) 18390-18395 2011
Kenji Ishihara, Shuhei Okuyama, Shun Kumano, Koji Iida, Hiroshi Hamana, Michio Murakoshi, Toshimitsu Kobayashi, Shinichi Usami, Katsuhisa Ikeda, Yoichi Haga, Kohei Tsumoto, Hiroyuki Nakamura, Noriyasu Hirasawa, Hiroshi Wada
Hearing Research 270(1-2) 110-118 2010
Shun Kumano, Koji Iida, Kenji Ishihara, Michio Murakoshi, Kouhei Tsumoto, Katsuhisa Ikeda, Izumi Kumagai, Toshimitsu Kobayashi, Hiroshi Wada
FEBS Letters 584(11) 2327-2332 2010
Shun Kumano, Michio Murakoshi, Koji Iida, Hiroshi Hamana, Hiroshi Wada
FEBS Letters 584(13) 2872-2876 2010
Shun KUMANO, Xiandong Tan, David Z.Z.He, Koji IIDA, Michio MURAKOSHI, Hiroshi WADA
Biochemical and Biophysical Research Communications 389(4) 569-574 2009
Michio Murakoshi, Koji Iida, Shun Kumano, Hiroshi Wada.
Pflugers Archiv - European Journal of Physiology 457(4) 885-898 2009
Murakoshi M, Wada H
Methods in molecular biology (Clifton, N.J.) 493 401-413 2009 [Refereed]
Koji IIDA, Michio MURAKOSHI, Shun KUMANO, Kouhei TSUMOTO, Katsuhisa IKEDA, Toshimitsu KOBAYASHI, Izumi KUMAGAI and Hiroshi WADA.
Journal of Biomechanical Science and Engineering 3(2) 221-234 2008
Takashi TADENUMA, Koji IIDA, Michio MURAKOSHI, Shun KUMANO, Kouhei TSUMOTO, Katsuhisa IKEDA, Toshimitsu KOBAYASHI, Izumi KUMAGAI and Hiroshi WADA.
Journal of Biomechanical Science and Engineering 3(2) 287-298 2008
Kenji Ishihara, Motoko Kaneko, Hajime Kitamura, Aki Takahashi, Jang Ja Hong, Toshio Seyama, Koji Iida, Hiroshi Wada, Noriyasu Hirasawa, Kazuo Ohuchi.
International Archives of Allergy and Immunology 146 7-10 2008
Recent findings on our auditory system: It is highly sensitive owing to the motility of sensory cells
H. Wada.
International Journal of Acoustics and Vibration 12 75-82 2007
安居 晃啓，芳賀 洋一， 陳 俊傑，伊関 洋，江刺 正喜，和田 仁
IEEJ Trans. SM 127(2) 69-74 2007
H. Wada, K. Iida, M. Murakoshi, S. Kumano, K. Tsumoto, K. Ikeda, I. Kumagai and T. Kobayashi
Biomechanics at Micro- and Nanoscale Levels, Vol. Ⅳ 3-13 2007
Y. Kitsunai, N. Yoshida, M. Murakoshi, K. Iida, S. Kumano, T. Kobayashi, H. Wada
Brain Research 1177 47-58 2007
Michio Murakoshi, Takashi Gomi, Koji Iida, Shun Kumano, Kouhei Tsumoto, Izumi Kumagai, Katsuhisa Ikeda, Toshimitsu Kobayashi and Hiroshi Wada
JARO- Journal of the Association for Research in Otolaryngology 7(3) 267-278 2006
Michio Murakoshi, Naohiro Yoshida, Yoko Kitsunai, Koji Iida, Shun Kumano, Takashi Suzuki, Toshimitsu Kobayashi and Hiroshi Wada
Brain Res. 1107 121-130 2006
M. Murakoshi, N. Yoshida, T. Kobayashi and H. Wada
Auris Nasus Larynx 33(2) 149-157 2006
H. Wada, K. Iida, S. Kumano, M. Murakoshi, K. Tsumoto, K. Ikeda, I. Kumagai and T. Kobayashi
Biomechanics at Micro- and Nanoscale Levels, Vol.Ⅱ 2 3-15 2006
Toshihiro MATSUI, Chihiro NAKAJIMA, Yuichi YAMAMOTO, Masayoshi ANDOH, Koji IIDA, Michio MURAKOSHI, Shun KUMANO and Hiroshi WADA
JSME International Journal 49(3) 828-836 2006
T. Koike, M. Murakoshi, S. Hamanishi, Y. Yuasa, R. Yuasa, T. Kobayashi and H. Wada
International Journal of Audiology 45(2) 121-128 2006
T. Kawase, S. Kano, T. Otsuka, S. Hamanishi, T. Koike, T. Kobayashi and H. Wada.
Otol. Neurotol. 27(5) 600-603 2006
芳賀洋一, 赤堀寛昌, 戸津健太郎, 和田 仁, 江刺正喜
レーザー研究 33(11) 754-760 2005
Shinji HAMANISHI, Takuji KOIKE, Wade CHIEN, Michael E. RAVICZ, John J. ROSOWSKI, Saumil N. MERCHANT, Toshimitsu KOBAYASHI and Hiroshi WADA
JSME International Journal 48(4) 529-536 2005
Takuji KOIKE, Masaki SHINOZAKI, Sayuri MURAKAMI, Kyoji Homma, Toshimitsu KOBAYASHI, and Hiroshi WADA
JSME International Journal 48(4) 521-528 2005
Shun KUMANO, Koji IIDA, Michio MURAKOSHI, Naoyuki NAITO, Kouhei TSUMOTO, Katsuhisa IKEDA, Izumi KUMAGAI, Toshimitsu KOBAYASHI, and Hiroshi WADA
JSME International Journal 48(4) 403-410 2005
Andoh, M., Nakajima, C., Wada, H.
J. Acoust. Soc. Am. 118(3,Pt.1) 1554-1565 2005
Ando, M., Hashimoto, E., Hashizume, H., Hyodo, K., Inoue, H., Kunisada, T., Maksimenko, A., Mori, K., Rubenstein, E., Roberson, J., Shimao, D., Sugiyama, H., Takeda, K., Toyofuku, F., Ueno, E., Umetani, K., Wada, H., Pattanasiriwisawa, W.
Nucl. Instrum. Methods. Phys. Res. A 548(1-2) 1-16 2005
Koji Iida, Kouhei Tsumoto, Katsuhisa Ikeda, Izumi Kumagai, Toshimitsu Kobayashi, Hiroshi Wada
Hearing Research 205(1-2) 262-270 2005
H. Wada, M. Sugawara, K. Kimura, Y. Ishida, T. Gomi, M. Murakoshi, Y. Katori, S. Kakehata, K. Ikeda and T. Kobayashi
Biomechanics at Micro- and Nanoscale Levels, Vol. I 3-15 2005
Sugawara M, Ishida Y, Wada H
Hearing research 192(1-2) 57-64 Jun 2004 [Refereed]
K. Iida, T. Nagaoka, K. Tsumoto, K. Ikeda, I. Kumagai, T. Kobayashi and H. Wada
JSME International Journal 47(4) 970-976 2004
Shingi Hamanishi, Takuji Koike, Hidetoshi Matsuki, and Hiroshi Wada
IEEE Transactions on Magnetics 40(5) 3387-3393 2004
Development of X-ray dark-field imaging towards clinical application
ANDO Masami, HASHIMOTO Eiko, HASHIZUME Hiroyuki, HYODO Kazuyuki, INOUE Hajime, ISHIKAWA Tetsuya, KUNISADA Toshiyuki, MAKSIMENKO Anton, PATTANASIRIWISAWA Wanwisa, RUBENSTEIN Edward, ROBERSON Joseph, SHIMAO Daisuke, SUGIYAMA Hiroshi, TAKEDA Ken, UENO Ei, WADA Hiroshi
NUCLEAR SCIENCE AND TECHNIQUES 15(3) 129-139 2004
M. Andoh and H. Wada
J. Acoust. Soc. Am., 116(1) 417-425 2004
Hiroshi Wada, Kei Kimura, Takashi Gomi, Michiko Sugawara, Yukio Katori, Seiji Kakehata, Katsuhisa Ikeda and Toshimitsu Kobayashi.
Hearing Research 187(1-2) 51-62 2004
Transient evoked otoacoustic emissions in patients with middle ear disorders.
Zhao F, Wada H, Koike T, Ohyama K, Kawase T, Stephens D
International journal of audiology 42(3) 117-131 Apr 2003 [Refereed]
Fixation of the anterior mallear ligament: Diagnosis and consequences for hearing results in stapes surgery.
Huber A, Koike T, Wada H, Nandapalan V, Fisch U.
Annals of otology Rhinology & Laryngology 112 348-355 2003
末梢聴覚系の働き
和田 仁
日本音響学会誌 59(1) 32-35 2003
和田 仁
臨床検査 47(10) 1161-1163 2003
Takuji KOIKE, Hiroshi WADA, Fumiaki ITO, Kazuyoshi TAKAYAMA and Toshimitsu KOBAYASHI.
JSME International Journal 46(4) 1434-1440 2003
Koji IIDA, Kazuaki KONNO, Takeshi OSHIMA, Kouhei TSUMOTO, Katsuhisa IKEDA, Izumi KUMAGAI, Toshimitsu KOBAYASHI and Hiroshi WADA
JSME International Journal 46(4) 1266-1274 2003
Masayoshi ANDOH and Hiroshi WADA
JSME International Journal 46(4) 1256-1265 2003
Transiently evoked otoacoustic emissions in patients with middle ear disorders
Fei Zhao, Hiroshi Wada, Takuji Koike, Kenji Ohyama, Tetsuaki Kawase and Dafydd Stephens
International Journal of Audiology 42 117-131 2003
Hiroshi Wada, Hiroto Usukura, Michiko Sugawara, Yukio Katori, Seiji Kakehata, Katsuhisa Ikeda and Toshimitsu Kobayashi
Hearing Research 177(1-2) 61-70 2003
Hiroshi Wada, Masayoshi Ando, Masataka Takeuchi, Hironori Sugawara, Takuji Koike, Toshimitsu Kobayashi, Koji Hozawa, Takashi Genma and Makoto Nara
J. Acoust. Soc.Am. 111(5,Pt.1) 2189-2199 2002
Hiroshi WADA, Daisuke MIYAMOTO and Michiko SUGAWARA
JSME International Journal, Series C 45(4) 862-869 2002
Hiroshi Wada, Akira Takeda and Tetsuaki Kawase
Hearing Research 165(1-2) 165-176 2002
Michiko Sugawara, Yuya Ishida and Hiroshi Wada
Hearing Research 174(1-2) 222-229 2002
T,Koike,H.Wada,T.Kobayaashi
Audiology Japan 45(4) 289-297 2002
Middle Ear Dynamic Characteristics in Patients with Otosclerosis
Fei Zhao, Hiroshi Wada, Takuji Koike, Kenji Ohyama, Tetsuaki Kawase and Dafydd Stephens
Ear & Hearing 23 150-158 2002
Takuji Koike and Hiroshi Wada
J. Acoust..Soc.Am., 111(3) 1306-1317 2002
H.Wada, H.Usukura, S. Takeuchi, M. Sugawara, S. Kakehata and K. Ikeda
Hearing Research 162(1-2) 10-18 2001
Hiroshi Wada, Takuji Koike, Yu Yuasa, Tetsuaki Kawase and Hiroaki Fujii
Hearing Research 154(1-2) 158-164 2001
Analysis of Force Production of the Auditory Sensory Cell
Michiko Sugawara and Hiroshi Wada
Proceedings of 8th International Congress on Sound and Vibration 917-924 2001
Effect of Conical Shape of Tympanic Membrane on Middle Ear Sound Transmission
Takuji Koike and Hiroshi Wada
Proceedings of 8th International Congress on Sound and Vibration 911-916 2001
Takuji KOIKE, Hiroshi WADA and Toshimitsu KOBAYASHI
JSME International Journal, Series C, 44(4) 1097-1102 2001
Auditory Mechanics
Hiroshi Wada
Proceedings of 8th International Congress on Sound and Vibration 61-69 2001
Michiko Sugawara and Hiroshi Wada
Hearing Research 160(1-2) 63-72 2001
Hiroshi Wada, Akira Takeda, Kenji Ohyama, Tomonori Takasaka
Audiology Japan 43(3) 177-183 2000
Hiroshi Wada, Kenji Momose, Ryo Tokioka, Kohyu Fukunishi
Audiology Japan 43(4) 233-241 2000
Analysis of Electrically Driven Shape Changes in Various Parts of Outer Hair Cells
M. Sugawara, H. Wada, S. Takeuchi, H. Usukura, S. Kakehata, K. Ikeda and T. Takasaka
Proceedings of the International Symposium on Recent Developments in Auditory Mechanics 323-329 2000
Theoretical Analysis of Sound Transmission in Human Middle Ear and Its Effects on Otoacoustic Emissions
T. Koike, H. Wada, T. Kobayashi, K. Ohyama and T. Takasaka
Proceedings of the International Symposium on Recent Developments in Auditory Mechanics 71-77 2000
Takashi Ohshima, Takaya Nakajima, Hiroshi Wada, Katsuhisa Ikeda, Tomonori Takasaka
Biomedical and Biophysical Research Communications 273(1) 84-89 2000
F. Zhao, H. Wada, T. Koike, D. Stephens
Clin. Otolaryngol 25(1) 3-8 2000
Analysis of the Finite-Element Method of Transfer Function of Reconstructed Middle Ears and their Postoperative Changes
T. Koike, H. Wada and T. Kobayashi
The Function and Mechanics of Normal, Diseased and Reconstructed Middle Ears, Proceedings of the Second International Symposium on Middle-Ear Mechanics in Research and Otosurgery 309-320 2000
HIroshi WADA, Hidehiko SHOJI, Yo SUZAKI and Tomonori TAKASAKA
JSME (C) 65(636) 3309-3313 1999
Hiroshi Wada, Susumu Takeuchi, Michiko Sugawara, Seiji Kakehata, Katsuhisa Ikeda and Tomonori Takasaka
Otology Japan 9(2) 135-140 1999
Michiko Sugawara, Kuni H.Iwasa, Hiroshi Wada
Otology Japan 9(5) 535-541 1999
Hiroshi Wada, Takaya Nakajima, Kenji Ohyama
ORL 61(5) 252-258 1999
Hiroshi Wada, Yu Yuasa, Takuji Koike, Tetsuaki Kawase and Tomonori Takasaka
Audiology Japan 42(4) 237-242 1999
Hiroshi WADA, Michihiro TAKEDA, Takuji KOIKE, You SUZAKI, Toshimitsu KOBAYASHI and Kenji OHYAMA
JSME International Journal, Series C 42(3) 753-758 1999
Hiroshi Wada, Takaya Nakajima and Kenji Ohyama
Audiology Japan 42(3) 203-210 1999
Hiroshi Wada, Takuji Koike, Toshimitsu Kobayashi and Tomonori Takasaka
Ear and Hearing 19(3) 240-249 1998
Takuji Koike, HIroshi Wada, Toshimitsu Kobayashi, Tomonori Takasaka
Audiology Japan 41(6) 740-745 1998
Hiroshi Wada, Toshimitsu Kobayshi, Koji Hozawa, Takuji Koike, Tomonori Takasaka
Audiology Japan 41(4) 296-303 1998
Hiroshi Wada, Michiko Sugawara, Toshimitsu Kobayashi, Koji Hozawa and Tomonori Takasaka
Hearing Research 120(1/2) 1-6 1998
Hiroshi Wada and Michiko Sugawara
JSME(A) 64(622) 1738-1743 1998
Takuji Koike, Hiroshi Wada, Toshimitsu Kobayashi, Tomoniri Takasaka
Otology Japan 8(2) 87-92 1998
和田 仁
日本音響学会誌 54(12) 864-867 1998
鋭敏な聴覚機能に寄与すると推察される感覚細胞の可動性
和田 仁
日本機械学会誌 101 535-535 1998
「耳から音が出てくる」という現象、耳音響放射
和田 仁
翠巒 14-18 1998
Hiroshi Wada, Kenji Momose, Michiko Sugawara, Koji Hozawa and Tomonori Takasaka
Otology Japan 8(5) 511-515 1998
Y.Suzaki, H.Wada, K.Oyama, T.Kobayashi, K.Houzawa and T.Takasaka
J Otolaryngol Jpn 100(3) 342-350 1997
Hiroshi Wada,Kunihiko Satoh,Michiko Sugawara,Katsuhisa Ikeda,Masayuki Furukawa and Tomonori Takasaka
Otology Japan 7(2) 102-108 1997
超音波による鼓膜物性評価
和田 仁,朴沢孝治,川瀬哲明
超音波TECHNO 9(5) 46-49 1997
Dynamic Animation of the Human Middle and Inner Ear
Hiroshi Wada, Takuji Koike, Shu-ichi Noguchi, Toshimitsu Kobayashi and Kenji Ohyama
Proceedings of ASVA 241-244 1997
Analysis of Outer Hair Cell Motility using Elastic Shell Theory
Michiko Sugawara, Hiroshi Wada and Tomonori Takasaka
Proceedings of Sendai Ear Symposium, 7 75-78 1997
Three-dimensional finite-element method (FEM) analysis of the human middle ear
Hiroshi Wada, Takuji Koike and Toshimitsu Kobayashi
Proceedings of the International Workshop on Middle Ear Mechanics in Research and Otosurgery 76-81 1997
Yulian Zheng, Kenji Ohyama, Koji Hozawa, Hiroshi Wada and Tomonori Takasaka
Hearing Research 112(1/2) 167-174 1997
Misc
The Characteristics of Fracture Strength of Alumina Ceramics With a Small Notch
A. Toshimitsu Yokobori, Fumihiro Suzuki, Kazuhiko Usami, Hiroshi Kawamoto and Hiroshi Wada
JSFM 38(1) 1-6 2004
Vibration measurement of the tympanic membrane using the electronic speckle pattern interferometry
Hiroshi Wada, Masataka Takeuchi, Hironori Sugawara, Takuji Koike, Toshimitsu Kobayashi, Koji Hozawa, Takashi Gemma and Makoto Nara
Acoustical Society of Japan 56 379-383 2000
Direct Observation of Vibration and the Traveling Wave on the Basilar Membrane of the Guinea Pig
Shin Takahashi, Tomonori Takasaka, Kenji Ohyama and Hiroshi Wada
J Otolaryngol Jpn 99(11) 1684-1693 1996
Takuji Koike,Hiroshi Wada and Toshimitsu Kobayashi
The Journal of the Acoustical Society of Japan 52(9) 695-702 1996
Hiroshi Wada and Syuichi Noguchi
日本音響学会誌 50(9) 746-750 1994
JOHNS
和田仁,小林俊光
JOHNS 8 783-789 1992
H.Wada, T.Kobayashi, K.Ohyama and S.Nishimura
J. Acous. Soc. Jpn. 47 235-242 1991
H. Wada, T. Kobayashi and S. Nishimura
J. Acous. Soc. Jpn. 46 391-396 1990
H. Wada and T. Kobayashi
J. Otolaryngology Jpn. 91 521-527 1988
Artifical Middle Ear Model
Hiroshi Wada and Toshimitsu Kobayashi
J. Cli. Exp. Med., 145 45 1988
Books etc
Assessing Middle Ear Function in Infants
Plural Publishing 2011 ISBN:978-1-59756-391-8
ヘルスケアとバイオ医療のための先端デバイス機器
シーエムシー出版 2009 ISBN:978-4-7813-0120-4
Biomechanics at Micro- and Nanoscale Levels 公開シンポジウム「マイクロ・ナノバイオメカニクスの開拓」 講演収録集
丸善 2009
Auditory and Vestibular Research: Methods and Protocols (Methods in Molecular Biology 493)
Humana Press 2008 ISBN:1934115622
Handbook of Noise and Vibration Control
John Wiley & Sons Inc 2007
Conference Activities & Talks
Dynamic characteristics of the outer and middle ears in neonate
WADA Hiroshi
33rd World Congress of Audiology 19 Sep 2016
AFM imaging of the structure of the motor protein prestin purified and reconstituted into an artificial lipid bilayer [Invited]
WADA Hiroshi
The 4th Japan-Switzerland Workshop on Biomechanics Sep 2014
Shear motion in the organ of Corti opens and closes mechanoelectrical transduction channels located in the stereocilia of the sensory hair cells [Invited]
WADA Hiroshi
International Symposium on Mechanobiology 2014 Jun 2014
老人性難聴の工学的考察
平成23年度東北大学機械系同窓会通常総会・特別講演会 2012
Assessment of the dynamic characteristics of the middle ear in neonates using the sweep frequency impedance (SFI) meter
The 6th International Symposium on Middle-Ear Mechanics in Research and Otology 2012
Association Memberships
ARO (Association for Research in Otolaryngology)(1) ,
Acoustical Society of America(72) ,
Biophysical Society(115) ,
International Institute of Acoustics and Vibration(3) ,
International Society of Audiology(2) ,
日本機械学会(432) ,
日本音響学会(72) ,
日本ME学会(11) ,
日本耳鼻咽喉科学会(15) ,
日本耳科学会(11) ,
日本聴覚医学会(12) Works
生後5日以内診断可能な「新生児難聴スクリーニング装置」の実用化開発
2011 - 2012
マイクロポンプシステムを用いた分子シャペロンとして働く薬物投与による遺伝性難聴の革新的治療法の創生
2009 - 2012
早期診断可能な「新生児難聴スクリーニング装置」の開発
2010 - 2011
MEMS/NEMS人工聴覚器による感音難聴治療法開発
2010 - 2011
中耳・内耳疾患診断用「新生児難聴スクリーニング装置」の開発
2009 - 2010
Research Grants & Projects
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(挑戦的萌芽研究)
Project Year: 2011 - 2013 Investigator(s): Hiroshi WADA
A membrane potential control device, which induces the conformational changes of prestin expressed in the plasma membrane, has been newly developed. Microstructures and electrophysiological properties of the prestin-expressing culture cells and th...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2008 - 2011 Investigator(s): Hiroshi WADA
The SLC26A4 gene encodes the transmembrane protein pendrin, which is involved in the conditioning of the ion concentration in the endolymph of the inner ear. Mutations in the SLC26A4 gene cause sensorineuronal hearing loss. However, the mechanisms...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2006 - 2008 Investigator(s): Hiroshi WADA
Outer hair cells (OHCs), which are sensory cells in the mammalian cochlea, are able to elongate and contract in length in response to changes in memebrane potential. This motility is believed to amplify the motion of the cochlear partition generat...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究)
Project Year: 2003 - 2008 Investigator(s): Hiroshi WADA
The project performed by fourteen Japanese researchers can be summarized as follows. The essential diversity of phenomena in living organisms is controlled not by genes but rather by the interaction between the micro- or nanoscale structures in ce...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究)
Project Year: 2003 - 2007 Investigator(s): Hiroshi WADA
The aim of this project was to clarify the motor protein prestin, whose conformational change has been indicated to induce an elongation and contraction of outer hair cells in the inner ear. To this end, first, an attempt was made to observe the p...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2001 - 2003 Investigator(s): Hiroshi WADA
The organ of Corti (OC) in the cochlea transforms sounds into action potentials in auditory nerve fibers. As the extreme vulnerability to trauma exhibited by the cochlea prevents the experimental observation that could confirm the inherence in thi...
Inner Ear Function
Project Year: 2000 - 2000
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2001 Investigator(s): Hiroshi WADA
The ossicular chain, consisting of the malleus, incus and stapes, plays an important role in auditory mechanics. If some part of the ossicles becomes fixed, hearing loss occurs. In order to improve the level of hearing, the fixated part is replace...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 1999 - 2000 Investigator(s): Hiroshi WADA
It is estimated that the origin of the motility of the outer hair cell (OHC) in response to electrical stimulation is the conformational change of the motor protein in the lateral wall of the cell. However, this mechanism has not been clarified ye...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 1999 - 2000 Investigator(s): Hiroshi WADA
Although the amplitude of the tympanic membrane vibrations is only a few nanometers when we speak in a low voice, we can understand clearly what is being said. This is speculated to be due to the cochlear amplification which is based on the outer ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(試験研究(B), 基盤研究(A))
Project Year: 1995 - 1997 Investigator(s): Hiroshi WADA
Although some techniques for the measurement of tympanic membrane vibration have alreaby been existed, their sensitivity to vibration amplitude is poor, and they need high SPL for the measurement. As a result, they are not suitable for the clinica...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(一般研究(A))
Project Year: 1994 - 1996 Investigator(s): Hiroshi WADA
Although the amplitude of tympanic membrane vibrations is only a few nanometers when we speak in a low voice, we can understand clearly what is being said. This is speculated to be due to the cochlear amplification which is based on the outer hair...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(国際学術研究)
Project Year: 1993 - 1995 Investigator(s): Hiroshi WADA
Otoacoustic emissions (OAEs) are believed to originate from outer hair cell movement and are considered to be transmitted to the external auditory meatus through the middle ear in a retrograte fashion. Therefore, the effect of the middle ear on OA...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(試験研究(B))
Project Year: 1992 - 1994 Investigator(s): Hiroshi WADA
Although amplitude of tympanic membranc vibrations is only a few nanometer when we talk in a low voice, we can understand clearly what they say. This is speculated to be caused by cochlear amplification. Otoacoustic Emissions (OAEs) are recognized...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(試験研究(B))
Project Year: 1990 - 1991 Investigator(s): Hiroshi WADA
First, geometry of the finite-element method (FEM) middle ear model was determined from the measurement results of the human temporal bones by means of the computer aided three-dimensional reconstruction method. Then, mechanical properties and bou...
Development of a New Electromagnetic Hearing Device
Diagnostic Apparatus for Measuring Stapes Mobility
Visualization Technique for Measuring Dynamic Behavior in Nano Scale.
Patents
振動測定装置 (Apparatus of Vibration Measurement)
特開平10－170334
中耳動特性表示法および中耳動特性測定装置
公開平2-211125
Measuring method, measuring apparatus and indication method of the dynamical characteristics of middle ear
264310
