佐上郁子 (Ikuko Sagami) - マイポータル

基本情報

学位: 理学博士
理学修士

J-GLOBAL ID: 200901000420994034
researchmap会員ID: 1000005290

外部リンク: http://www.kpu.ac.jp/

研究分野

MISC

123

Effects of mutations in the heme domain on ・・・

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  Biochem. a・・・ 368 292-297 2008年

Characte・・・

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   Spectroscopic and DNA-・・・

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 CO-dependent activity-c・・・

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 J. Biol. Chem.  280 21358-21368 2005年

Analysis of the kinetics of CO binding to neuronal nitric oxide synthase by flash photolysis: dual effects of substrates, inhibitors, and tetrahydrobiopterin

S Bengea, Y Araki, O Ito, J Igarashi, Sagami, I, T Shimizu

JOURNAL OF INORGANIC BIOCHEMISTRY 98(7) 1210-1216 2004年7月

Importance of valine 567 in substrate recognition and oxidation by neuronal nitric oxide synthase

M Moreau, H Takahashi, MA Sari, JL Boucher, Sagami, I, T Shimizu, D Mansuy

JOURNAL OF INORGANIC BIOCHEMISTRY 98(7) 1200-1209 2004年7月

Arg410 near the heme proximal ligand of neuronal nitric oxide synthase is critical for both substrate recognition and electron transfer

J Yadav, S Fujiwara, Sagami, I, T Shimizu

CHEMISTRY LETTERS 33(6) 752-753 2004年6月

A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor

H Kurokawa, DS Lee, M Watanabe, Sagami, I, B Mikami, CS Raman, T Shimizu

JOURNAL OF BIOLOGICAL CHEMISTRY 279(19) 20186-20193 2004年5月

Identification of caveolin-1-interacting sites in neuronal nitric-oxide synthase - Molecular mechanism for inhibition of NO formation

Y Sato, Sagami, I, T Shimizu

JOURNAL OF BIOLOGICAL CHEMISTRY 279(10) 8827-8836 2004年3月

Critical roles of Asp40 at the heme proximal side of heme-regulated phosphodiesterase from E. Coli in redox-potential, autooxidation, and CAT

Eur J Biochem. 271, 3937-42. 2004年

Activation of heme-regulated eukaryotic initiation factor 2alpha kinase (HRI) by nitric oxide Is induced by the formation of a five-coordinated NO-heme complex: Optical absorption, electron spin resonance and resonance raman spectral studies.

J. Biol. Chem. 279,15752-15762 2004年

Binding of oxygen and carbon monoxide to a heme-regulated phosphodiesterase from Escherichia coli - Kinetics and infrared spectra of the full-length wild-type enzyme, isolated PAS domain, and Met-95 mutants

S Taguchi, T Matsui, J Igarashi, Y Sasakura, Y Araki, O Ito, S Sugiyama, Sagami, I, T Shimizu

JOURNAL OF BIOLOGICAL CHEMISTRY 279(5) 3340-3347 2004年1月

Relationships between, Heme Incorporation、Tetramer Formation and Catalysis of a Heme-regulated Phosphodiesterase from Escherichia coli: : A Study of Deletion and Site-directed Mutants

J. Biol. Chem. 278(52) 53105-53111 2003年12月

CO binding study of mouse heme-regulated eIF-2 alpha kinase: kinetics and resonance Raman spectra

J Igarashi, A Sato, T Kitagawa, Sagami, I, T Shimizu

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1650(1-2) 99-104 2003年8月

Cyanide binding study of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate binding site

J Yadav, Sagami, I, T Shimizu

JOURNAL OF INORGANIC BIOCHEMISTRY 95(1) 25-30 2003年5月

Structure-function relationships of NO synthase: electron transfer reaction

Sagami, I, Y Sato, T Shimizu

SEIKAGAKU 75(5) 351-358 2003年5月

Cyanide binding study of neuronal nitric oxide synthase: Effects of inhibitors and mutations at the substrate binding site

Jyoti Yadav, Ikuko Sagami, Toru Shimizu

Journal of Inorganic Biochemistry 95(1) 25-30 2003年5月1日

CO binding to the isolated oxygenase domain of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate-binding site

S Bengea, Sagami, I, T Shimizu

JOURNAL OF INORGANIC BIOCHEMISTRY 94(4) 343-347 2003年4月

もっとみる

書籍等出版物
5

部位特異的アミノ酸置換

東京化学同人ポストシークエンス；タンパク質実験法２ 2003年

P450の分子生物学

講談社サイエンティフィク 2003年

Site-directed Mutagenesis

Tokyo-Kagaku Doujin Post-sequence; Methods in Protein Chemistory 2003年

Cloning and characterization of three forms of cytochrome P-450 in 3-methylcholanthrene-treated hamster livers.

Cytochrome P-450. Biochemistry and Biophysics. Archakor, A. I. Bachmanova, G. I. ed. 1992年

Cloning and characterization of three forms of cytochrome P-450 in 3-methylcholanthrene-treated hamster livers.

Cytochrome P-450. Biochemistry and Biophysics. Archakor, A. I. Bachmanova, G. I. ed. 1992年

所属学協会
4

日本生物物理学会

日本分子生物学会

日本癌学会

日本生化学会

共同研究・競争的資金等の研究課題
6

時計遺伝子を司る転写因子の制御機構

2003年

酸素センサ-の解析

NO合成酵素の発現と機能解析

Analysis of oxygen Sensor

Expression of NO synthase and structurald analysis of NO synthase

Regulation of Cytocrome P-450IA(CYPIA) gene expression

産業財産権
1

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