論文

査読有り
2004年

Effect of a nutritive-tonic drink on stress-induced serum glucocorticoid in the mouse

American Journal of Chinese Medicine
  • Yasuko Sakata
  • ,
  • Kentaro Ayada
  • ,
  • Yoshihisa Ito
  • ,
  • Takeshi Tadano
  • ,
  • Yasuo Endo

32
6
開始ページ
851
終了ページ
861
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1142/S0192415X04002466

We evaluated stress during "restraint with gnawing (R+G+)" and "restraint without gnawing (R+G-)" in a mouse system. R+G- induced a higher serum glucocorticoid level than R+G+. Zena F-III (a nutritive-tonic drink prescribed as "Kampo", a traditional Japanese medicine with its origin in Chinese medicine) reduced the glucocorticoid elevation in R+G+, but not in R+G-. These results support the hypotheses that (i) activity, such as gnawing, which potentially leading to escape from distress, reduces the severity of emotional distress and (ii) Zena F-III reduces the severity of mental or emotional fatigue, or increases motivation, in a stressful situation that the animal can manage itself. © 2004 World Scientific Publishing Company.

リンク情報
DOI
https://doi.org/10.1142/S0192415X04002466
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/15673191

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