Toshio Sasajima - My portal

Profile Information

J-GLOBAL ID: 200901095108681496
researchmap Member ID: 1000006429

Research Interests

Research Areas

Life sciences / Neurosurgery /

Education

- 1991

Akita University
- 1991

Neurosurgery, Graduate School, Division of Medicine, Akita University
- 1986

School of Medicine, School of Medicine, Akita University
- 1986

Faculty of Medicine, Akita University

Papers

Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-beta, and/or bevacizumab for glioblastoma

Takahiro Ono, Toshio Sasajima, Yoshihiro Doi, Shuntaro Oka, Masahiro Ono, Masaru Kanagawa, Atsumi Baden, Kazuo Mizoi, Hiroaki Shimizu

NUCLEAR MEDICINE AND BIOLOGY, 42(7) 598-607, Jul, 2015 Peer-reviewed
Rapid immunohistochemistry based on alternating current electric field for intraoperative diagnosis of brain tumors (vol 32, pg 12, 2015)

Mishie Tanino, Toshio Sasajima, Hiroshi Nanjo, Shiori Akesaka, Masami Kagaya, Taichi Kimura, Yusuke Ishida, Masaya Oda, Masataka Takahashi, Taku Sugawara …

BRAIN TUMOR PATHOLOGY, 32(1) 20-21, Jan, 2015 Peer-reviewed
Rapid immunohistochemistry based on alternating current electric field for intraoperative diagnosis of brain tumors

Mishie Tanino, Toshio Sasajima, Hiroshi Nanjo, Shiori Akesaka, Masami Kagaya, Taichi Kimura, Yusuke Ishida, Masaya Oda, Masataka Takahashi, Taku Sugawara …

BRAIN TUMOR PATHOLOGY, 32(1) 12-19, Jan, 2015 Peer-reviewed
Treatment outcomes in glioblastoma patients aged 76 years or older: a multicenter retrospective cohort study

Takeo Uzuka, Kenichiro Asano, Toshio Sasajima, Kaori Sakurada, Toshihiro Kumabe, Takaaki Beppu, Masahiro Ichikawa, Chifumi Kitanaka, Hiroshi Aoki, Kiyoshi Saito …

JOURNAL OF NEURO-ONCOLOGY, 116(2) 299-306, Jan, 2014 Peer-reviewed
Trans-1-amino-3-F-18-fluorocyclobutanecarboxylic acid (anti-F-18-FACBC) is a feasible alternative to C-11-methyl-L-methionine and magnetic resonance imaging for monitoring treatment response in gliomas

Toshio Sasajima, Takahiro Ono, Naoya Shimada, Yoshihiro Doi, Shuntaro Oka, Masaru Kanagawa, Atsumi Baden, Kazuo Mizoi

NUCLEAR MEDICINE AND BIOLOGY, 40(6) 808-815, Aug, 2013 Peer-reviewed
Cerebellar hemangioblastoma with marked pleomorphism: A case report

Takahiro Ono, Toshio Sasajima, Masaya Oda, Kazuo Mizoi

Neurological Surgery, 40(7) 643-650, Jul, 2012 Peer-reviewed
Association of stem cell marker CD133 expression with dissemination of glioblastomas

Atsushi Sato, Kaori Sakurada, Toshihiro Kumabe, Toshio Sasajima, Takaaki Beppu, Kenichiro Asano, Hiroki Ohkuma, Akira Ogawa, Kazuo Mizoi, Teiji Tominaga …

NEUROSURGICAL REVIEW, 33(2) 175-183, Apr, 2010 Peer-reviewed
[Glioblastoma multiforme developing separately from the initial lesion 9 years after successful treatment for gliomatosis cerebri: a case report].

Inoue T, Kanamori M, Sonoda Y, Watanabe M, Sasajima T, Kamisato N, Kumabe T, Tominaga T

No shinkei geka. Neurological surgery, 36(8) 709-715, Aug, 2008 Peer-reviewed
Negative pressure pulmonary edema following foramen magnum decompression for Chiari malformation type I

Yoshitaka Hirano, Taku Sugawara, Yoshiharu Sato, Koji Sato, Tomoya Omae, Toshio Sasajima, Kazuo Mizoi

NEUROLOGIA MEDICO-CHIRURGICA, 48(3) 137-139, Mar, 2008 Peer-reviewed
99mTc-MIBI imaging for prediction of therapeutic effects of second-generation MDR1 inhibitors in malignant brain tumors.

Sasajima T, Shimada N, Naitoh Y, Takahashi M, Hu Y, Satoh T, Mizoi K

Int J Cancer, 121 2637-2645, 2007
I-123-metaiodobenzylguanidine single-photon emission computerized tomography in brain tumors - a preliminary study

T Sasajima, H Kinouchi, Y Naitoh, N Tomura, J Watarai, K Mizoi

JOURNAL OF NEURO-ONCOLOGY, 77(2) 185-191, Apr, 2006
[Three-dimensional surface anatomical scanning with 3D-FSPGR: anatomical conformity with surgical findings].

Narita K, Tomura N, Sasajima T, Sakuma I, Sakurada W, Sasaki M, Hatakeyama K, Sasaki H, Saitou T, Shimizu H …

Nihon Hoshasen Gijutsu Gakkai zasshi, 61(9) 1341-1348, Sep, 2005 Peer-reviewed
Simultaneous microscopic and endoscopic monitoring during surgery for internal carotid artery aneurysms

H Kinouchi, T Yanagisawa, A Suzuki, T Ohta, Y Hirano, T Sugawara, T Sasajima, K Mizoi

JOURNAL OF NEUROSURGERY, 101(6) 989-995, Dec, 2004 Peer-reviewed
Proliferation-dependent changes in amino acid transport and glucose metabolism in glioma cell lines

T Sasajima, T Miyagawa, T Oku, JG Gelovani, R Finn, R Blasberg

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 31(9) 1244-1256, Sep, 2004
[Unusual MR appearance of intracranial dissemination from cervical glioblastoma].

Kawashima A, Sasajima T, Sugawara T, Takahashi M, Suzuki A, Higashiyama N, Kinouchi H, Mizoi K

No shinkei geka. Neurological surgery, 32(9) 937-944, Sep, 2004 Peer-reviewed
[A case of pleomorphic TSH-producing pituitary adenoma with calcification].

Yamaguchi S, Sasajima T, Takahashi M, Kinouchi H, Suzuki A, Yoshioka N, Itoh S, Mizoi K

No shinkei geka. Neurological surgery, 32(9) 961-967, Sep, 2004 Peer-reviewed
[Supratentorial primitive neuroectodermal tumor: report of a surgical case].

Omae T, Takahashi M, Sasajima T, Sugawara T, Kinouchi H, Higashiyama N, Mizoi K

No shinkei geka. Neurological surgery, 32(6) 619-625, Jun, 2004 Peer-reviewed
Direct repair of a blisterlike aneurysm on the internal carotid artery with vascular closure staple clips. Technical note.

Yanagisawa T, Mizoi K, Sugawara T, Suzuki A, Ohta T, Higashiyama N, Takahashi M, Sasajima T, Kinouchi H

Journal of neurosurgery, 100(1) 146-149, Jan, 2004 Peer-reviewed
Assessment of treatment response by autoradiography with C-14-aminocyclopentane carboxylic acid, Ga-67-DTPA, and F-18-FDG in a herpes simplex virus thymidine kinase/ganciclovir brain tumor model

T Miyagawa, T Oku, T Sasajima, R Dasai, B Beattie, R Finn, JG Tjuvajev, R Blasberg

JOURNAL OF NUCLEAR MEDICINE, 44(11) 1845-1854, Nov, 2003 Peer-reviewed
[A case of metastatic suprasellar tumor with edema along the optic pathway].

Takahashi M, Kinouchi H, Sasajima T, Suzuki A, Mizoi K

No shinkei geka. Neurological surgery, 31(7) 775-779, Jul, 2003 Peer-reviewed

Misc.

160

血管内治療と二期的摘出術が有用であった大型・hypervascular聴神経腫瘍の1手術例

高橋和孝, 松本康史, 山口卓, 小野隆裕, 小田正哉, 笹嶋寿郎, 清水宏明

脳神経外科ジャーナル, 24(8) 544-551, Aug, 2015
迅速免疫組織化学染色を用いた膠腫におけるIDH1染色の術中応用

廣嶋優子, 南條博, 前田大地, 後藤明輝, 笹嶋寿郎, 清水宏明, 南谷佳弘, 津田真寿美, 田中伸哉

日本病理学会会誌, 104(1) 296-296, Mar, 2015
迅速免疫染色技術(R-IHC)を用いた術中迅速病理診断当院における180症例の検討

南條博, 吉岡年明, 廣嶋優子, 南谷佳弘, 笹嶋寿郎, 吉田誠, 後藤明輝, 大森泰文, 中村竜太, 赤上陽一

日本病理学会会誌, 104(1) 465-465, Mar, 2015
【神経症候群(第2版)-その他の神経疾患を含めて-】腫瘍性疾患神経上皮性腫瘍そのほかの神経上皮性腫瘍第三脳室脊索腫様膠腫

笹嶋寿郎

日本臨床, 別冊(神経症候群III) 105-108, Jun, 2014
新しい細胞診機器・技術機械化・LBC・画像解析電界非接触撹拌迅速免疫染色技術(R-IHC法)の開発と組織・細胞診断への活用

南條博, 南谷佳弘, 伊藤智, 成田かすみ, 川村学, 廣嶋優子, 吉岡年明, 後藤明輝, 笹嶋寿郎, 赤上陽一

日本臨床細胞学会雑誌, 53(Suppl.1) 116-116, Apr, 2014
電界非接触撹拌迅速免疫染色技術を用いた術中迅速病理診断

南條博, 吉岡年明, 南谷佳弘, 笹嶋寿郎, 廣嶋優子, 吉田誠, 後藤明輝, 赤上陽一

日本病理学会会誌, 103(1) 234-234, Mar, 2014
傍鞍部に発生したextrasinusal dural AVFの1手術例

柳澤俊晴, 近藤類, 佐々木絵里奈, 笹嶋寿郎, 渡邉克夫, 溝井和夫

東北脳血管障害研究会学術集会記録集, 35回 186-198, Dec, 2013
脳腫瘍の術中病理診断における電界撹拌技術を搭載した迅速免疫染色装置の有用性

谷野美智枝, 笹嶋寿郎, 明坂詩織, 渡辺麻那美, 木村太一, 西原広史, 南條博, 南谷佳弘, 溝井和夫, 田中伸哉

Brain Tumor Pathology, 30(Suppl.) 130-130, May, 2013
秋田で開発した迅速免疫組織染色技術を用いた術中迅速病理診断の有用性

南條博, 吉岡年明, 高橋正人, 吉田誠, 廣嶋優子, 笹嶋寿郎, 南谷佳弘, 赤上陽一, 後藤明輝

日本病理学会会誌, 102(1) 349-349, Apr, 2013
後頭蓋窩のextra-sinusal dural AVFの3例

柳澤俊晴, 柴田憲一, 東山巨樹, 菅原卓, 笹嶋寿郎, 溝井和夫

東北脳血管障害研究会学術集会記録集, 34回 225-245, Dec, 2012
顕著なpleomorphismを呈した小脳血管芽腫の1例

小野隆裕, 笹嶋寿郎, 小田正哉, 溝井和夫

Neurological Surgery, 40(7) 643-650, Jul, 2012
診断に苦慮した右メッケル腔病変の1例

武田芳子, 松田雅純, 華園晃, 鎌田幸子, 大川聡, 菅原正伯, 大西洋英, 菅原卓, 東山巨樹, 笹嶋寿郎 …

臨床神経学, 52(7) 527-527, Jul, 2012
3D-surface anatomy scan(SAS)の新たな試み

成田孔明, 櫻田渉, 高橋聡, 大谷隆浩, 橋本学, 笹嶋寿郎

日本放射線技術学会総会学術大会予稿集, 68回 230-230, Feb, 2012
痙攣発作で発症した未破裂中大脳動脈瘤の1例

柳澤俊晴, 柴田憲一, 島田直也, 鈴木明, 笹嶋寿郎, 溝井和夫

東北脳血管障害研究会学術集会記録集, 33回 31-35, Dec, 2011
Neuroradiological diagnosis of extraaxial tumors of the brain

戸村則昭, 笹嶋寿郎

Japanese journal of clinical radiology, 56(5) 617-624, May, 2011
【頭蓋内腫瘤性病変の画像診断】脳実質外腫瘍

戸村則昭, 笹嶋寿郎

臨床放射線, 56(5) 617-624, May, 2011
非機能性下垂体腺腫に対するfractionated stereotactic radiotherapyの治療成績

鈴木明, 羽入紀朋, 笹嶋寿郎, 古賀誠, 高橋和孝, 島田直也, 柴田憲一, 橋本学, 溝井和夫

定位的放射線治療, 15 85-94, Apr, 2011
脳動脈瘤クリッピング術における蛍光血管撮影の経験

柳澤俊晴, 柴田憲一, 島田直也, 笹嶋寿郎, 溝井和夫

東北脳血管障害研究会学術集会記録集, 32回 17-21, Dec, 2010
Gliomatosis cerebriの1例

松田雅純, 大川聡, 菅原正伯, 笹嶋寿郎, 高橋和孝, 溝井和夫, 後藤博美, 伊崎堅志, 豊島至

臨床神経学, 50(3) 206-206, Mar, 2010
脳腫瘍に合併した脳血管もやもや病

菅原真人, 佐久間郁郎, 高橋聡, 戸村則昭, 渡会二郎, 笹嶋寿郎, 溝井和夫

Japanese Journal of Radiology, 27(Suppl.) 4-4, Apr, 2009

Books and Other Publications

Early effects of intracarotid recombinant human tumor necrosis factor α on cerebral blood flow and glucose metabolism

Clinical PET in Oncology, 1994

Professional Memberships

Research Projects

Experimental studies of synthesized amino acid analog anti-FACBC as imaging biomarker to monitor treatment response of glioblatomas to temozolomide therapy with interferon-. and bevacizumab

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2010 - 2012

Toshio SASAJIMA
Development of a novel multi-modal surgical navigation system with the integration of three-dimensional cerebrovascular imaging data.

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2008 - 2010

Kazuo MIZOI, Toshio SASAJIMA
Experimental studies of CD133(+) glioblastoma stem cells under normoxic and hypoxic conditions

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2007 - 2008

Toshio SASAJIMA
Development of the multimodal neuronavigation system integrating structural and functional information in combination with intra-operative ultrasound imaging.

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2006 - 2007

Kazuo MIZOI, Toshio SASAJIMA
Establishment of cortical mapping of speech areas by multimodal functional image fusions using neuronavigation system

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2004 - 2005

Kazuo MIZOI, Toshio SASAJIMA
Experimental studies on potentiation of antitumor agent by the second generation MDR1 inhibitors in malignant brain tumors : Monitoring multidrug resistance using ^<99m>Tc-MIBI

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2004 - 2005

Toshio SASAJIMA
Integrated analysis of language area using MEG, functional MRI and PET. -Clinical application to brain tumor surgery-

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2002 - 2003

Kazuo MIZOI, Toshio SASAJIMA
Experimental studies of antitumor effects ofangiogenesis inhibitor TNP-470 with a chemotherapeutic agent on a malignant brain tumor.

Grants-in-Aid for Scientific Research(基盤研究(B)), 基盤研究(B), Ministry of Education, Culture, Sports, Science and Technology, 2000 - 2001

Kazuo MIZOI, Toshio SASAJIMA
Monitoring the functional expression of multidrug resistance gene (MDR1) and study on potentiation of antitumor agent by MDR1 inhibitors in brain tumors.

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 1999 - 2000

Toshio SASAJIMA
脳腫瘍における低酸素細胞の増殖能と糖およびアミノ酸代謝に関する研究

科学研究費補助金(奨励研究(A)), 奨励研究(A), 文部科学省, 1997 - 1998

笹嶋寿郎
脳腫瘍における腫瘍壊死因子動注療法による循環代謝の変動と治療効果に関する研究

科学研究費補助金(奨励研究(A)), 奨励研究(A), 文部科学省, 1994 - 1994

笹嶋寿郎
脳腫瘍におけるアミノ酸代謝とシスプラチンの作用機序に関する研究

科学研究費補助金(奨励研究(A)), 奨励研究(A), 文部科学省, 1993 - 1993

笹嶋寿郎
Experimental studies of antitumor effects of angiogenesis inhibitor TNP-470 with a chemotherapeutic agent on maliqnant gliomas.

The Other Research Programs