MISC

1998年8月

Impact of diffusional oxygen transport on oxidative metabolism in the heart

JAPANESE JOURNAL OF PHYSIOLOGY
  • E Takahashi
  • ,
  • K Doi

48
4
開始ページ
243
終了ページ
252
記述言語
英語
掲載種別
書評論文,書評,文献紹介等
DOI
10.2170/jjphysiol.48.243
出版者・発行元
CENTER ACADEMIC PUBL JAPAN

The resistance for the oxygen molecule to diffuse from the capillary blood to the cell surface produces remarkably large gradients of oxygen partial pressure (PO(2)) in the extracellular space. In addition, the intracellular radial gradients of PO(2) may not be ignored particularly when the cellular oxygen consumption is increased. These PO(2) gradients together result in a quite low intracellular PO(2) in the cardiomyocyte in vivo. Thus, the cellular oxidative metabolism may be limited by diffusional transport of oxygen from the capillary blood to mitochondria, In this review, quantitative aspects and physiological relevances of the PO(2) gradient in the myocardium are discussed.

リンク情報
DOI
https://doi.org/10.2170/jjphysiol.48.243
CiNii Articles
http://ci.nii.ac.jp/naid/10008304843
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/9757140
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000076252500003&DestApp=WOS_CPL
ID情報
  • DOI : 10.2170/jjphysiol.48.243
  • ISSN : 0021-521X
  • CiNii Articles ID : 10008304843
  • PubMed ID : 9757140
  • Web of Science ID : WOS:000076252500003

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