1998年8月
Impact of diffusional oxygen transport on oxidative metabolism in the heart
JAPANESE JOURNAL OF PHYSIOLOGY
- ,
- 巻
- 48
- 号
- 4
- 開始ページ
- 243
- 終了ページ
- 252
- 記述言語
- 英語
- 掲載種別
- 書評論文,書評,文献紹介等
- DOI
- 10.2170/jjphysiol.48.243
- 出版者・発行元
- CENTER ACADEMIC PUBL JAPAN
The resistance for the oxygen molecule to diffuse from the capillary blood to the cell surface produces remarkably large gradients of oxygen partial pressure (PO(2)) in the extracellular space. In addition, the intracellular radial gradients of PO(2) may not be ignored particularly when the cellular oxygen consumption is increased. These PO(2) gradients together result in a quite low intracellular PO(2) in the cardiomyocyte in vivo. Thus, the cellular oxidative metabolism may be limited by diffusional transport of oxygen from the capillary blood to mitochondria, In this review, quantitative aspects and physiological relevances of the PO(2) gradient in the myocardium are discussed.
- リンク情報
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- DOI
- https://doi.org/10.2170/jjphysiol.48.243
- CiNii Articles
- http://ci.nii.ac.jp/naid/10008304843
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/9757140
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000076252500003&DestApp=WOS_CPL
- ID情報
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- DOI : 10.2170/jjphysiol.48.243
- ISSN : 0021-521X
- CiNii Articles ID : 10008304843
- PubMed ID : 9757140
- Web of Science ID : WOS:000076252500003