HIRAI Mitsuhiro

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Name
HIRAI Mitsuhiro
URL
http://www.tech.gunma-u.ac.jp/gakka/hirai/index.html
Affiliation
Gunma University
Job title
Professor
Degree
(BLANK)(Tohoku University), (BLANK)(Tohoku University)

Research Areas

 

Academic & Professional Experience

 
1999
 - 
2000
Guest scientist of GKSS Research Center
 

Education

 
 
 - 
1985
Graduate School, Division of Natural Science, Tohoku University
 
 
 - 
1978
Faculty of Science, Shinshu University
 

Published Papers

 
Recovery effects of acid denaturation/aggregation of proteins
HIRAI Mitsuhiro
Bunsekikagaku   68(1) 43-49   Jan 2019   [Refereed]
Sugar-mediated stabilization of protein against chemical or thermal denaturation
HIRAI Mitsuhiro
J. Phys. Chem. B   122 8685-8697   Dec 2018   [Refereed]
Mitsuhiro Hirai, Satoshi Ajito, Masaaki Sugiyama, Hiroki Iwase, Shin-ichi Takata, Nobutaka Shimizu, Noriyuki Igarashi, Anne Martel, Lionel Porcar
PHYSICA B-CONDENSED MATTER   551 212-217   2018   [Refereed]
Satoshi Ajito, Mitsuhiro Hirai, Hiroki Iwase, Nobutaka Shimizu, Noriyuki Igarashi, Noboru Ohta
PHYSICA B-CONDENSED MATTER   551 249-255   2018   [Refereed]
Restoration of Myoglobin Native Fold from Its Initial State of Amyloid Formation by Trehalose
M. Hirai, S. Ajito, H. Iwase, S. Takata, N. Ohta, N. Igarashi, N. Shimizu
J. Phys. Chem. B   122 11962-11968   2018   [Refereed]
Preferential Intercalation of human amyloid-β peptide into inter-bilayer region of lipid-raft membrane in macromolecular crowding environment
M. Hirai, S. Ajito, S. Sato, N. Ohta, N. Igarashi, N. Shimizu
J. Phys. Chem. B   122 9482-9489   2018   [Refereed]
Direct evidence for the effect of glycerol on protein hydration and thermal structural transition.
M. Hirai, S. Ajito, M. Sugiyama, H. Iwase, S. Takata, N. Shimizu, N. Igarashi, A. Martel, and L. Porcar
Biophys. J.   115 313-327   2018   [Refereed]
Frozen state of sephadex® gels of different crosslink density analyzed by X-ray computed tomography and X-ray diffraction
N. Murase, Y. Uetake, Y. Sato, K. Irie, Y. Ueno, T. Hirauchi, T. Kawahara, and M. Hirai
Gels   4 1-12   2018   [Refereed]
Structural studies on the perireceptor proteins involving in the chemoreception
HIRAI Mitsuhiro
Euro. Biophys. J. Biophys. Lett.   46 s377-s366   2017   [Refereed]
Mitsuhiro Hirai, Satoshi Ajito, Kosuke Takahashi, Kazuki Takeuchi, Ryota Kimura, Tatsuo Iwasa
SPring-8 Section A: Scientific Research Report   5 27-31   2017   [Refereed]
Sugiyama, Masaaki; Yagi, Hirokazu; Yamaguchi, Takumi; Kumoi, Kentaro; Hirai, Mitsuhiro; Oba, Yojiro; Sato, Nobuhiro; Porcar, Lionel; Martel, Anne; Kato, Koichi
JOURNAL OF APPLIED CRYSTALLOGRAPHY   47(1) 430-435   2014   [Refereed]
Conformational characterization of a protein complex involving intrinsically disordered protein by small-angle neutron scattering using the inverse contrast matching method: a case study of interaction between alpha-synuclein and PbaB tetramer as ...
Okuda, Hiroshi; Yamamoto, Takayoshi; Takeshita, Kohki; Hirai, Mitsuhiro; Senoo, Kazunobu; Ogawa, Hiroki; Kitajima, Yoshinori
JAPANESE JOURNAL OF APPLIED PHYSICS   53(5) 05FH02   2014   [Refereed]
Hirai, Mitsuhiro; Kimura, Ryota; Takeuchi, Kazuki; Hagiwara, Yoshihiko; Kawai-Hirai, Rika; Ohta, Noboru; Igarashi, Noriyuki; Shimuzu, Nobutaka
JOURNAL OF SYNCHROTRON RADIATION   20(6) 869-874   2013   [Refereed]
Hirai, Mitushiro; Kimura, Ryota; Takeuchi, Kazuki; Sugiyama, Masaaki; Kasahara, Kouji; Ohta, Noboru; Farago, Bela; Stadler, Andreas; Zaccai, Giuseppe
EUROPEAN PHYSICAL JOURNAL E   36(7) 74   2013   [Refereed]
M. Hirai, Y. Hagiwara, K. Takeuchi, R. Kimura, T. Onai, R. K. Hirai, N. Ohta, M. Sugiyama
Thermochimica Acta   532 15-21   2012   [Refereed]
Kinetic Asymmetry of Subunit Exchange of Homooligomeric Protein as Revealed by Deuteration-Assisted Small-Angle Neutron Scattering.
M. Sugiyama, E. Kurimoto, H. Yagi, K. Mori, T. Fukunaga, M. Hirai, G. Zaccai, and K. Kato.
Biophys. J.   101 2037-2042   2011   [Refereed]
Recent Development and Prospects of Neutron Scattering Study of Biomaterials Mainly on Biomembrane
Mitsuhiro HIRAI
Journal of the Vacuum Society of Japan   53(12) 739-746   2010
E. Fabiani, A. M. Stadler, D. Madern, M. M. Koza, M. Tehei, M. Hirai, and G. Zaccai.
Eur. Biophys. J.   38 237-244   2009   [Refereed]
Effect of alcohols on glycosphingolipid aggregates
T. Onai, and M. Hirai.
Trans. Material Res. Soc. Jpn.   33 567-572   2008   [Refereed]
HIRAI MITSUHIRO / T. Hayakawa / A. Makino / S. Michaud / M. Lagarde / A. Douteau / K. Ito, / T. Kobayashi
MEMBRANE   32 221-228   2007   [Refereed]
Effect of cations on the structure of sodium bis(2-ethylhexyl)sulfosuccinate water-in-oil microemulsion
HIRAI MITSUHIRO / R. Kawai-Hirai
J. Appl. Cryst.   40 s274-s278   2007   [Refereed]
HIRAI MITSUHIRO / T. Onai / M. Koizumi / H. Hirai / K. Kasahara / N. Suzuki / K. Yuyama / K. Inoue
J. Appl. Cryst.   40 s159-s164   2007   [Refereed]
Collapse of the hydration shell of a protein prior to thermal unfolding
HIRAI MITSUHIRO/ M. Koizumi / H. Hirai / T. Onai / K. Inoue
J. Appl. Cryst.   40 s175-s178   2007   [Refereed]
M. Hirai
J. Phys. : Conference Series   83 012003-1 - 012003-6   2007   [Refereed]
T. Onai and M. Hirai
J. Phys. : Conference Series   83 012016-1 - 012016-7-292   2007   [Refereed]
HIRAI MITSUHIRO / T. Onai / M. Koizumi / H. Lu, / K. Inoue
J. Appl. Cryst.   40 s184-s189   2007   [Refereed]
Thermal unfolding process of proteins depending on structural hierarchy clarified by wide-angle X-ray scattering at a third generation synchrotron source.
HIRAI MITSUHIRO / KOIZUMI MASAHARU / K. Inoue
Bunseki Kagaku   55 411-418   2006   [Refereed]
HIRAI MITSUHIRO / H. Hirai / M. Koizumi / K. Kasahara / K. Yuyama / N. Suzuki
Physica B   385-386 868-870   2006   [Refereed]
HIRAI MITSUHIRO / T. Abraham / M. Hato
Biotechnol. Prog.   21 255-262   2005   [Refereed]
T. Abraham , M. Hato / HIRAI MITSUHIRO
Colloid Surface B   35 107-117   2004   [Refereed]
HIRAI MITSUHIRO / KOIZUMI MASAHARU / TAKAHASHI HIROSHI / ABE SATORU / T. Hayakawa / H. Hirai / K. Miura / K. Inoue
Biochemistry   43 9036-9049   2004   [Refereed]
T. Hirai, S. Kobayashi, M. Hirai, M. Yamaguchi, M. Z. Uddin, M. Watanabe, H. Shirai
Proceedings of SPIE - The International Society for Optical Engineering   5385 433?441   2004   [Refereed]
HIRAI MITSUHIRO / R. K. Hirai
Journal of Applied Crystalography   36 520-524   2003   [Refereed]
HIRAI MITSUHIRO
Journal of Applied Crystalography   36 489-493   2003   [Refereed]
HIRAI MITSUHIRO / TAKAHASHI HIROSHI / 岩瀬 裕希 / 早川 智宏
Biophysical Journal   85 1600-1610   2003   [Refereed]
HIRAI MITSUHIRO / T. Hayakawa
Analytical Chemistry   75 6728-6731   2003   [Refereed]
Right-circular and left-circular orientation of biological macromolecules under magnetic field
HIRAI MITSUHIRO / M. Koizumi / R. Han / T. Hayakawa / Y. Sano
J. Appl. Cryst.   36 520-524   2003   [Refereed]
HIRAI MITSUHIRO / R. Kawai-Hirai / H. Iwase / T. Hayakawa / Y. Kawabata / T. Takeda
Applied Physics A   vol.74 s1254-s1256   2002   [Refereed]
HAYAKAWA TOMOHIRO / HIRAI MITSUHIRO
European Biophysics Journal   31 62-72   2002   [Refereed]
HIRAI MITSUHIRO / H. Iwase / T. Hayakawa / K. Miura / K. Inoue
Journal of Synchrotron Radiation   9 202-205   2002   [Refereed]
Small-angle neutron scattering study of w/o AOT microemulsion entrapping proteins
HIRAI MITSUHIRO
Studies in Surface Science and Catalysis   132 201-204   2001   [Refereed]
Simulations of neutron sdvent contrast variation of proteins and intramolecular structures
HIRAI MITSUHIRO / H. Iwase
Journal of Physical Society of Japan   70 417-419   2001   [Refereed]
Structure and dynamics of glycosphingolipid micelle
HIRAI MITSUHIRO / H. Iwase / T. Hayakawa
Journal of Physical Society of Japan   70 420-423   2001   [Refereed]
HIRAI MITSUHIRO / S. Mitsuya / Y. Sano
Molecular Crystal and Liquid Crystal   367 3439-3448   2001   [Refereed]
HIRAI MITSUHIRO / IWASE HIROKI
Molecular Crystals and Liquid Crystals   367 661-669   2001   [Refereed]
Compact permanent magnetic circuit with periodic magnetic field designed for studies of liquid crystals.
HIRAI MITSUHIRO / S. Mitsuya / H. Iwase / T. Hayakawa / Y. Aoyama / K. Ohashi / Y. Sano
Molecular Crystal and Liquid Crystal   367 3429-3438   2001   [Refereed]
HAYAKAWA TOMOHIRO / HIRAI MITSUHIRO
Molecular Crystal and Liquid Crystal   367 3419-3428   2001   [Refereed]
AOT microemulsion structure depending on both apolar solvent and protein Concentration.
HIRAI RIKA /HIRAI MITSUHIRO / H. Futatsugi / H. Iwase / T. Hayakawa
Studies in Surface Science and Catalysis   132 165-168   2001   [Refereed]
Comparison of DMSO-induced denaturation of hen egg-white lysozyme and bovine α-lactalbumin.
HIRAI MITSUHIRO
Journal of Physics and Chemistry of Solids.   60 1379-1381   1999   [Refereed]
Internal structural change of ganglioside micelle depending on temperature observed by neutron solvent contrast variation.
HIRAI MITSUHIRO
Journal of Physics and Chemistry of Solids   60 1297-1299   1999   [Refereed]
HIRAI MITSUHIRO
The Journal of Physical Chemistry B   103 9658-9662   1999   [Refereed]
HIRAI MITSUHIRO
The Journal of Physical Chemistry B   103 10136-10142   1999   [Refereed]
HIRAI MITSUHIRO
Biophysical Journal   76 2192-2197   1999   [Refereed]
HIRAI MITSUHIRO
The Journal of Physical Chemistry B   102 1303-1313   1998   [Refereed]
HIRAI MITSUHIRO
Biophysical Journal   74 1380-1387   1998   [Refereed]
Response to Cantu et al.
HIRAI MITSUHIRO
Biophysical Journal   74 1604-1605   1998   [Refereed]
HIRAI MITSUHIRO
Thermochimica Acta   308 93-99   1998   [Refereed]
HIRAI MITSUHIRO
Physica B   241-243 1159-1161   1998   [Refereed]
Intensive extrusion-and occlussion of water in ganglioside micelle with thermal reversibility
HIRAI MITSUHIRO
Biophysical Journal   74/,3010-3014    1998   [Refereed]
HIRAI MITSUHIRO
Physica B   241-243 984-986   1998   [Refereed]
HIRAI MITSUHIRO
Thermochimica Acta   308 101-107   1998   [Refereed]
HIRAI MITSUHIRO
Chemistry Letters   26 773-774   1997   [Refereed]
Neutron scattering study of phosphatidylinositol 4,5-bis(phosphate)aqueous dispersion
HIRAI MITSUHIRO
Progress in Colloid and Polymer Science   106 237-241   1997   [Refereed]
Structural study of protein-glycolipid interaction
HIRAI MITSUHIRO
Progress in Colloid and Polymer Sceience   106 232-236   1997   [Refereed]
M. Hirai, T. Takizawa, S. Yabuki, T. Hirai1 and K. Hayashi
Biophysical Journal   70 1761-1768   1996   [Refereed]
HIRAI MITSUHIRO
Die Angewande Macromolekulare Chemie   240 221-229   1996   [Refereed]
M. Hirai, T. Takizawa, S. Yabuki and K. Hayashi
Journal of the Chemical Society, Farady Transcations   92 4533-4540   1996   [Refereed]
M. Hirai, T. Takizawa, S. Yabuki, Y. Nakata, T. Hirai and K. Hayashi
Journal of the Chemical Society, Faraday Transactions   92 1493-1498   1996   [Refereed]
Yoshiro NAKATA, Toshiharu TAKIZAWA, Sadato YABUKI, Mitsuhiro HIRAI
The Journal of Chemical Software   3 29-36   1996   [Refereed]
HIRAI MITSUHIRO
Die Angewande Macromolekulare Chemie   240 213-219   1996   [Refereed]
M. Hirai, T. Takizawa, S. Yabuki, T. Hirai1 and K. Hayashi
J. Phys. Chem.   100 11675-11680   1996   [Refereed]
Time-transient process of magnetically induced growth of nematic domains in a biological macromolecular liquid crystal
HIRAI MITSUHIRO
Physical Review E   51 1263-1267   1995   [Refereed]
Structure and reactivity of aerosol-OT reversed micelles containing α-chymotrypsin
HIRAI MITSUHIRO
Journal of the Chemical Society, Faraday Transactions   51 1081-1089   1995   [Refereed]
Electrically Induced Reversible Structural Change of a Highly Swollen Polymer Gel Network
HIRAI MITSUHIRO
Journal of Chemical Society Faraday Transaction   91 473-477   1995   [Refereed]
M. Hirai, T. Takizawa, S. Yabuki, Y. Nakata, H. Mitomo, T. Hirai, S. Shimizu, K. Kobayashi, M. Furusaka, and K. Hayashi
Physica B   213&214 751-753   1995   [Refereed]
M. Hirai, T. Takizawa, S. Yabuki, T. Hirai, and K. Hayashi
Journal of Physical Chemistry   99 17456-17460   1995   [Refereed]
T. Takizawa, M. Hirai, S. Yabuki, Y. Nakata, A. Takahashi and K. Hayashi
Thermochimica Acta   267 355-364   1995   [Refereed]
M. Hirai, S. Yabuki, T. Takizawa, Y. Nakata, H. Mitomo, T. Hirai, S. Shimizu, K. Kobayashi, M. Furusaka, and K. Hayashi
Physica B   213&214 748-750   1995   [Refereed]
H. Hirata, H. Yuuki, T. Ogasawara, K. Taga, T. Yoshida, H. Okabayashi, M. Furusaka, T. Kawakatsu, K. Kawasaki, and M. Hirai
Physica B   213&214 588-590   1995   [Refereed]
Aerosol-OT reversed micellar formation at low water-surfactant ratio by synchrotron radiation small-angle X-ray scattering
HIRAI MITSUHIRO
Journal of Physical Chemistry   99 6652-6660   1995   [Refereed]
Electrostriction of highly swollen polymer gel-A possible application for gel actuator.
HIRAI MITSUHIRO
Journal of Applied Polymer Science   53/,79-84    1994
Effect of branching of amylopectin on complexation with iodine as steric hinderance
HIRAI MITSUHIRO
Polymer   35 2222-2225   1994   [Refereed]
Growing Process of Scattering Density Fluctuation of a Medium Distance in Hydrogel of Poly(vinyl alcohol)under Stretching
HIRAI MITSUHIRO
Macromolecules   27 1003-1006   1994   [Refereed]
High-performance magnetic circuit designed for small-angle X-ray scattering using synchrotron radiation source
HIRAI MITSUHIRO
Nuclear Instruments and Methods in physics Research   A340 620-624   1994   [Refereed]
Actuation of poly(vinyl alcohol)gel by electric field
HIRAI MITSUHIRO
Journal of Intelligent Material Systems & Structures   4 277-279   1993   [Refereed]
Conformation change on polymer chains of partially formalized poly(vinyl alcohol)-iodine color complex studied by using synchrotron radiation small-angle X-ray solution scattering
HIRAI MITSUHIRO
Makromolekulare Chemie   194 2885-2895   1993   [Refereed]
Structural changes of jack bean urease induced by addition of surfactants studied with synchrotron radiation small-angle X-ray scattering
HIRAI MITSUHIRO
European Journal of Biochemistry   215 55-61   1993   [Refereed]
Small-angle thermal neutron spectrometer
HIRAI MITSUHIRO
Physica B   180&181 941-943   1992   [Refereed]
Study on amylose conformation change induced by complexation with iodine-iodide using synchrotron radiation X-ray small-angle scattering
HIRAI MITSUHIRO
Macromolecules   25 6699-6702   1992   [Refereed]
A new polarized target for neutron scattering studies on biomolecules : First results from apoferritin and the deutrated 50s subunit of ribosomes
HIRAI MITSUHIRO
Journal of Applied Crystallography   25 155-165   1992   [Refereed]
Thermal neutron small-angle scattering spectrometer (WIT)
HIRAI MITSUHIRO
Proceedings of the Eleven Meeting of the International Collaboration on Advanced Neutron Sources (ICANS-XI)      1991
Polarized neutron scatting from dynamic polarized targets in biology
HIRAI MITSUHIRO
Physica B   174    1991
Several experiences of using 6Li glass scintillators
HIRAI MITSUHIRO
Proceedings of the Eleventh Meeting of the International Collaboration on Advanced Neutron Sources (ICANS-XI)      1991
A new polarized target for structure studies on biomolecules at GKSS
HIRAI MITSUHIRO
Proceedings of the Eleventh Meeting of the International Collaboration on Advanced Neutron Souries (ICANS-XI)   49-55   1991   [Refereed]
Thermal neutron small-angle scattering spectrometer (WIT) using 2-D converging slit and annular glass scintillator detector at KENS
N. Niimura, M. Hirai, A. Ishida, K. Aizawa, K. Yamada, and M. Ueno
Physica B   156-157 611-614   1989   [Refereed]

Misc

 
Effect of ultra-fine bubble water on the structure of protein and lipid membrane
M. Hirai, S. Ajito, K. Takahashi, K. Tomita, Y. Maezawa
Photon Factory Activity Report   34 37   2017
Structure and solvation of protein under molecular crowding environment
M. Hirai
MLF Experimental Report   2016B 2016B0003   2017
Study of protein structure and its stability, unfolding and refolding processes in concentrated sugar solutions
M. Hirai, S. Ajito, K. Takahashi, Y. Maezawa, D. Wen, J. Kamimura, T. Kimura, X. Geng, T. Iwasa
SPring-8 User Experiment Report   2017A1435 A1435   2017
EFFECT OF MOLECULAR CROWDING ON PROTEIN STRUCTURE STABILITY AND HYDRATION
M. Hirai, T. Takeuchi, R. Kimura
SPring-8 User Experiment Report   2015A 2015A1557   2016
Effect of Crowding Environments on Protein Structure Below 0°C
M. Hirai, R. Kimura, T. Takeuchi, T. Iwasa
SPring-8 User Experiment Report   2015B 2015B1489   2016
Effect of ultra-fine bubble water on protein structure
M. Hirai, S. Ajito, K. Takahashi, T. Iwasa
SPring-8 User Experiment Report   2016A 2016A1487   2016
Structural studies on the peri-receptor protein of chemoreception
M. Hirai, R. Kimura, T. Takeuchi, T. Iwasa
SPring-8 User Experiment Report   2015B 2015B1355   2016
Structural characteristics of liposome entrapping protein depending on lipid composition and temperature
M. Hirai, K. Takahashi, S. Ajito, Y. Maezawa, K. Tomita, T.Iwasa,
SPring-8 User Experiment Report   2016B 2016B1381   2016
M. Hirai, T. Takeuchi, R. Kimura
SPring-8 User Experiment Report   2014B(8) 2014B1072-3406   2015
Interaction between Aβ protein and raft-model membrane observed by wide-angle X-ray scattering
M. Hirai, T. Takeuchi, R. Kimura
SPring-8 User Experiment Report   2013B 2013B1387   2014
Amyloid transition of proteins under crowding environment observed by WAXS
M. Hirai, T. Takeuchi, R. Kimura
SPring-8 User Experiment Report   29(2012B) 2012B1095   2013
Interaction between lipid-raft model membrane and amylioid beta protein
M. Hirai, K. Takeuchi, and R. Kimura
Photon Factory Activity Report   30(B) 302   2013
Thermal structural transition of protein observed by anomalous dispersion of X-ray
M. Hirai, T. Takeuchi, R. Kimura
SPring-8 User Experiment Report   2013A 2013A1409   2013
Resonant small- and wide-angle X-ray scattering (A-SWAXS) experiments of metallo proteins in solutions
M. Hirai, T. Takeuchi, R. Kimura, T. Iwasa, N. Watanabe, and N. Ohta
SPring-8 User Experiment Report   29(2012A) 2012A1077   2012
Study of Structural Stability of Protein Entrapped in Lipid Liposome
M. Hirai, R. Kimura, T. Takeuchi, T. Iwasa, and N. Watanabe
SPring-8 User Experiment Report   28(2011B) 2011B1574   2012
Assembly of the Archaeal 20S Proteasome and its Newly Discovered Chaperon-like Proteins
M. Sugiyama,, K. Kato, M. Sato, M. Hirai, K. Kumori, T. Oda, H. Yagi
Annual Report of Institut Laue-Langevin   2011 DIR-98   2012
Characterization of structure of liposome occluding protein
M. Hirai, R. Kimura, T. Takeuchi, M. Sugiyama, T. Iwasa, and N. Shimizu.
SPring-8 User Experiment Report   2011A 2011A1929   2011
Effect of co-solute on protein structure at equilibrium
M. Hirai, T. Takeuchi, R. Kimura, M. Sugiyama, T. Iwasa, and N. Shimizu.
SPring-8 User Experiment Report   2011A    2011
Thermal unfolding and refolding of protein under osmotic pressure.
M. Hirai, Y. Hagiwara, T. Onai, and N. Ohta.   26 (2010B) 2010B1452   2011
Effect of osmotic stress on protein folding
M. Hirai, Y. Hagiwara, T. Onai.
Photon Factory Activity Report   27(A) 213   2010
SANS Study of Kinetics of Subunit Exchange in Proteasome alpha-Ring.
M. Sugiyama, M. Hirai, K. Kato, E. Kurimoto, Y. Morimoto.
Annual Report of Institut Laue-Langevin   2009 8-03-622   2010
Structure characteristics of liposomes entrapping proteins
H. Hagiwara, T. Onai, M. Hirai
SPring-8 User Experiment Report   2009 2009B1730   2009
Structural transition of protein and wide-angle X-ray scattering: Study of protein folding under osmotic pressure
Mitsuhiro Hirai
KEK Proceedings   2008-8 87-90   2008
Structure change of liposome containing glycosphingolipids under osmotic stress
Teruaki Onai, Mitsuhiro Hirai
KEK Proceedings   2008-8 51-54   2008
Structure of SUVs of lipid mixtures composed of glycosphingolipid, cholesterol and phospholipid depending on lipid molar ratio and salt concentration
T. Onai, and M. Hirai.
Photon Factory Activity Report   25 228   2008
Observation of Nucleation and Growth of Amyloid Formation of Apomyoglobin by using WAXS
M. Hirai/T. Onai/G. Chin/D. Man/T. Iwasa
SPring-8 User Experiment Report   20 (2007B) 2007B1780   2008
Effect of interaction between amyloid-protein and lipid-raft on membrane dynamics
M. Hirai, K. Kasahara, T. Onai, B. Farago, and G. Zaccai.
Annual Report of Institut Laue-Langevin   2008 8-02-454   2008
Effect of glycosphingolipid on amyloid transition of apomyoglobin
T. Onai, M. Hirai, M. Koizumi, H. Hirai, K. Kasahara, N. Suzuki, and K. Yuyama.
Photon Factory Activity Report   24 240   2007
Effect of Osmotic Pressure On Unfolding-Refolding of Globular Protein
M. Hirai/T. Onai/G. Chin/K. Inoue
SPring-8 User Experiment Report   19 (2007A) 2007A1006   2007
Morphology transition of glycosphingolipid/cholesterol/phospholipid mixtures
HIRAI MITSUHIRO / T. Onai / M. Koizumi / K. Kasahara / N. Suzuki / K. Yuyama
SPring-8 User Experiment Report17 (2006B), 231   17 (2006B) 231   2007
Dynamics of the alpha-beta transition in Apomyoglobin studied by Elastic and Quasi-elastic scattering experiments
A. STADLER, E. FABIANI, G. ZACCAI , M. HIRAI.
Annual Report of Institut Laue-Langevin   2006 8-04-395   2006
Wide-angle scattering study of intramolecular structural change of apomyoglobin and role of glycolipids in the process of amyloid formation
HIRAI MITSUHIRO / M. Koizumi / H. Hirai / K. Kasahara / N. Suzuki
SPring-8 User Experiment Report   16 (2006A) 185   2006
Structure and dynamics of lipid raft membrane and interaction with amyloidStructure and dynamics of lipid raft membrane and interaction with amyloid
M. Hirai, K. Kasahara, K. Yuyama, S.Naoko, K. Masaharu, M. Roland, F.Giovanna , and G. Zaccai.
Annual Report of Institut Laue-Langevin   2005 8-02-378   2005
Wide-angle X-ray scattering can reveal hierarchical map of unfolding-refolding transition of protein.
HIRAI MITSUHIRO / KOIZUMI MASAHARU
SPring-8 Research Frontiers-2004   5 26-27   2005
Maximum miscibility of cholesterol to ganglioside
HIRAI MITSUHIRO / KOIZUMI MASAHARU / 平井 春顕 / 笠原 浩二 / 湯山 耕平 / 鈴木 直子
SPring-8 User Experiment Report   15 (2005A) 192   2005
Hierarchal map of protein unfolding observed by WAXS method
HIRAI MITSUHIRO / KOIZUMI MASAHARU / 平井 春顕 / 笠原 浩二 / 鈴木 直子 / 湯山 耕平
SPring-8 User Experiment Report   14 (2004B) 189   2005
Interaction of cholera toxin B-subunits with ganglioside/cholesterol/phospholipid mixture.
HIRAI MITSUHIRO
Photon Factory Activity Report   20 234   2004
Wide-angle scattering revealing internal structure of proteins.
HIRAI MITSUHIRO
Photon Factory Activity Report   20 231   2004
Interaction of ganglioside with its antibody
HIRAI MITSUHIRO / KOIZUMI MASAHARU / ABE SATORU / 平井 春顕 / 笠原 浩二 / 湯山 耕平 / 鈴木 直子
SPring-8 User Experiment Report   13 (2004A), 203.    2004
X-ray diffraction studies on the effect of undecaprenol in the subgel phase of phosphatidylcholine bilayers.
HIRAI MITSUHIRO
SPring-8 User Experiment Report   vol.11 (2003A) 214   2003
Growth of amyloid fibril interacting with ganglioside-containing vesicle
HIRAI MITSUHIRO / T. Hayakawa / M. Koizumi / H. Takahashi / N. Suzuki / K. Yuyama / K. Kasahara
SPring-8 User Experiment Report   vol.11 (2003A) 214   2003
Strcutre and Dynamics of Ganglioside/Cholestrol/DPPC Mixed Vesicle
HIRAI MITSUHIRO / T. Hayakawa / K. Koizumi
Activity Report on Neutron Scattering Research   vol.10 197   2003
Interaction of ganglioside-containing vesicle with cholera toxin B-subunits
HIRAI MITSUHIRO / T. Hayakawa / L. Han / M. Koizumi / H. Takahashi / K. Miura / K. Inoue
SPring-8 User Experiment Report   vol.10 (2002B) 181   2003
X-ray diffraction studies on the undecaprenol on the subgel phase of phosphatidylcholine
TAKAHASHI HIROSHI / HIRAI MITSUHIRO / KOIZUMI MASAHARU / HAYAKAWA TOMOHIRO / ABE SATORU / Katsuaki Inoue
SPring-8 User Experiment Report   11 210   2003
Growth of amyloid fibril interacting with ganglioside-containing vesicle
HIRAI MITSUHIRO / KOIZUMI MASAHARU / 早川 智宏 / 笠原 浩二 / 湯山 耕平 / 鈴木 直子
SPring-8 User Experiment Report   11 (2003A) 214   2003
Dynamics of POPC vesicles containing glycosphingolipids and cholesterol observed by neutron spin echo
HIRAI MITSUHIRO / T. Hayakawa / K. Koizumi / R. Kan / H. Iwase
Activity Report on Neutron Scattering Research   vol. 9 201   2002
Wide-angle neutron scattering and structural hierarchy of proteins.
HIRAI MITSUHIRO
KENS REPORT   vol.13 208-209   2002
Phase behabior of glycoshpingolipid/cholesterol complex as a raft component
HIRAI MITSUHIRO / T. Hayakawa / L. Han / M. Koizumi / H. Takahashi / K. Miura / K. Inoue
SPring-8 User Experiment Report   vol.9 (2002A) 199   2002
Structure analysis of ganglioside/dipalmitoyl phosphatidylcholine vesicle using inverse contrast variation
HIRAI MITSUHIRO / T. Hayakawa / K. Koizumi / R. Kan / H. Iwase.
Activity Report on Neutron Scattering Research   vol.9 201   2002
Structure analysis of ganglioside/dipalmitoyl phosphatidylcholine vesicle using inverse contrast variation.
HIRAI MITSUHIRO / T. Hayakawa / K. Koizumi / R. Kan / H. Iwase
Activity Report on Neutron Scattering Research   vol.9 202   2002
X-ray diffraction studies on intact and delipidated insect cuticle: Architecture and assembly of cuticular protein and polysaccharide
TAKAHASHI HIROSHI / HIRAI MITSUHIRO / Chihiro Katagiri / Satoru Abe / Katsuaki Inoue / Keiko Miura
SPring-8 User Experiment Report   No.8 (2001B) 177   2002
Right-handed and left-handed orientation of biological macromolecules under magnetic field.
HIRAI MITSUHIRO / M. Koizumi / H. Iwase / T. Hayakawa / Y. Sano
Photon Factory Activity Report   vol. 18 244   2001
Effect of protein occlusion on w/o microemulsion structure.
HIRAI MITSUHIRO / T. Hayakawa
Photon Factory Activity Report   vol. 18 243   2001
Structure of ganglioside/cholesterol mixture.
HIRAI MITSUHIRO / T. Hayakawa / H. Iwase
Photon Factory Activity Report   vol. 18 242   2001
Effect of Occlusion of Proteins on AOT Microemulsion Structure.
HIRAI MITSUHIRO / R. K. Hirai / H. Iwase / T. Hayakawa / M. Nagao / M. Shibayama
Activity Report on Neutron Scattering Reseach   vol.8 227   2001
Temperature Dependence of Dynamics of Glycosphingolipid (GD1a) Micelle.
HIRAI MITSUHIRO
Activity Report on Neutron Scattering Reseach   vol.8, 226.    2001
Structural information revealed by wide-angle solution scattering of several proteins
HIRAI MITSUHIRO
SPring-8 User Experiment Report   4/,172    2000
Dynamics of w/o AOT microemulsions occluding proteins
HIRAI MITSUHIRO
Activity Report on Neutron Scattering Research   7/,267    2000
Comparison of phase behaviors of biological supermolecular suspensions under magnetic field.
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   42/,359-362    1999
AOT revesed micellar structure depending on apolar solvents.
HIRAI MITSUHIRO
Photon Factory Activity Report   16/,244    1999
Time-resolved SAXS study of ganglioside micelle under constant heating/cooling rate.
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   42/,131-134    1999
Comparison of intramolecular structures of lysozyme and α-lactalbumin.
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   42/,527-530    1999
Dynamics of w/o AOT microemulsions studied by neutron spin echo.
HIRAI MITSUHIRO
Activity Report on Neutron Scattering Reseach   5/,217    1998
Structure and function of biological noble lipids studied by neutron and synchrotron radiation X-ray.
HIRAI MITSUHIRO
KEK Proceedings   98-5/,211-214    1998
Reversible extrusion-and-occlusion of water in ganglioside micelle.
HIRAI MITSUHIRO
Photon Factory Activity Report   15/,35    1998
Neutron scattering study of AOT microemulsions using solvent contrast variation
HIRAI MITSUHIRO
Activity Report on Neutron Scattering Reseach   4/,203-204    1997
Bending actuators using polyurethane inomer
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   40/,409-412    1997
Photoinduced current of PVC-SBP membrane
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   40/,405-408    1997
Bending deformation of polyuretane films by electrostriction
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   40/,401-404    1997
Effect of the modification of the gel-surface layer on the wall shear stress
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   40/,195-198    1997
Structural study of AOT microemulsions using neutron contrast variation method
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   40/,579-582    1997
A method of thermal structural transition analysis of protein
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   40/,575-578    1997
Structural Study of aggregates formed by the insect lacciter product
HIRAI MITSUHIRO
Photon Factory Activity Report   13/,198    1996
Magnetic-field-strength dependence of orientational dynamics of tabacco mosaic virus nematic liguid crystal studied by using small-angle X-ray scattering
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   39/,587-590    1996
Thermotropic conformational change of lysozyme at low pH
HIRAI MITSUHIRO
Photon Factory Activity Report   13/,201    1996
Structural study of ganglioside/phospholipid aqueous dispersion
HIRAI MITSUHIRO
Photon Factory Activity Report   13/,197    1996
Effect of DC electric field on PVC-DOP structure
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   39/,367-370    1996
Structural change of PVA-PAA gel ; effect of esterification
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   39/,205-208    1996
Magnetic field clependent behavior of supermacromolecule liquid crystal
HIRAI MITSUHIRO
Photon Factory activity Report   13/,188    1996
Neutron scattering study of phosphatidylinositol 4,5-bis(phosphate)aqueous dispersion
HIRAI MITSUHIRO
Activity Report ON Newtron Scattering Research   3/,206-207    1996
Eftect of chemical crosslinks on the shrinking process of PVA hyarogel in aqueous methanol solution
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   39/,201-204    1996
DSC study of thermal denaturation of lyso zyme
HIRAI MITSUHIRO
Reports on Progress in Palymen Physics in Japan   39/,591-592    1996
Thermotropic structural tramsition of lysozyme studied by using small-angle X-ray scattering
HIRAI MITSUHIRO
Reports on Progress in Polymen Physics in Japan   39/,583-586    1996
Structural study of aerosol-OT microemulsions containing bovine serum albumin
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   38/,553-556    1995
Behavior of PVA-gel occluding ferrofluid as a magnetic-field-sensitive actuator
HIRAI MITSUHIRO
Activity Report on Neutron Scattering Reseach   2/,171    1995
Structural change of magnetic body In hydrogel
HIRAI MITSUHIRO
Photon Factory Activity Report   12/,289    1995
Effect of pH variation ion on ganglioside structure in solution
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   38/,545-548    1995
Structural change of polyurethane induced by electric field
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   38/,393-396    1995
Thermally induced structural change of polyurethane elastomer
HIRAI MITSUHIRO
Photon Factory Activity Report   12/,290    1995
Effect of variation of pH on ganglioside micellar structure in solution studied by using small-angle X-ray scattering
HIRAI MITSUHIRO
Photon Factory Activity Report   12/,217    1995
Thermal stability of ganglioside micellar structure in solution studied by using small-angle X-ray scattering
HIRAI MITSUHIRO
Photon Factory Activity Report   12/,216    1995
Magnetically induced structure change of polymer gel
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   38/,163-166    1995
Thermotropic phase transition of gangliosides in solution
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   38/,549-552    1995
Action of polyurethane elastomer by electric field
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan,   37/,417-420    1994
Structural study of ganglioside in solution using complimentary and solvent contrast variation methods
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   37/,655-658    1994
Contraction of poly(vinyl alcohol)hydrogel in acetone
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   37/,109-110    1994
Electrical action of plasticzed poly(vinyl chloride)
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   37/,111-112    1994
Effect of Ca2+ ion on the structure of phosphatidylinositol-diphoshate in solution
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   37/,651-654    1994
Shape memory of highly swollen poly(vinyl alcohol)hydrogel
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   36,89-92    1993
Electrostriction of Polyurethane Elastomers
HIRAI MITSUHIRO
Reports on Progress in Polymer Physics in Japan   36,341-342    1993

Books etc

 
Neutrons in Soft Matter
A John Wiley & Sons   2011   ISBN:978-0-470-40252-8

Conference Activities & Talks

 
Structures and dynamics of glycosphingolipid-containing lipid mixtures as raft models of plasma membrane.
HIRAI MITSUHIRO / KOIZUMI MASAHARU / 平井 春顕 / 早川 智宏 / 湯山耕平 / 笠原浩二 / 鈴木直子
J. Phys.: Condens. Matter   2005   
Thermal stability of w/o AOT microemulsion entrapping a-chymotrypsin.
The 18th IUPAC International Conferance on Chemical Thermodynamics   2004   
Structural study of glycosphingolipid-containing vesicle using inverse contrast variation: Complementary use of SANS & SAXS & DLS.
International Symposium on Pulsed Neutron Science (IPN2003)   2003   
Wide-angle X-ray scattering of proteins in solution: Application to protein folding study.
Satelite workshop of Biophysics and Synchrotron Radiation (BSR2004), "SAXS in the 21st Century   2004   
Structure and dynamics of liposomes of lipid mixtures as a model of raft
“Neutron in Biology”, Satellite Meeting of the IUPAB/EBSA Biophysics Congress   2005   

Research Grants & Projects

 
Role of glycolipids on microdomain formation (lipid-raft formation), structure and dynamics, and signaling in cell membrane
Project Year: 1998   
Study of control of molecular arrangement and crystallization of biological polymers using magnetic-field gradient
The Other Research Programs
Project Year: 1994   
Mechanism of protein folding and amyloid formation
Project Year: 1998   
activity, protein, microemulsion, reversed micelle, microreactor
Cooperative Research
Project Year: 1995