原幸男 (Yukio Hara) - マイポータル - researchmap

基本情報

所属: 北里大学獣医学部獣医学科教授

学位: 薬学博士(北里大学)
薬学修士(北里大学)

J-GLOBAL ID: 200901094767797454
researchmap会員ID: 1000009690

研究キーワード

4

研究分野

1

ライフサイエンス / 薬理学 /

学歴

4

- 1977年

北里大学, 薬学研究科, 薬理学
- 1977年

北里大学
- 1970年

東京薬科大学, 薬学部, 薬学科
- 1970年

Tokyo University of Pharmacy and Life Science, Faculty of Pharmaceutical Science

MISC

70

Changes in myocardial beta(1)-adrenergic receptor and stimulatory G-protein gene expression after chronic treatment with doxorubicin in rat

K Kizaki, K Akatsuka, M Momozaki, Y Fujimori, T Uchide, K Temma, Y Hara

JOURNAL OF VETERINARY MEDICAL SCIENCE 66(8) 989-992 2004年8月
Effects of anticancer chemotherapeutic drugs on the acetylcholine receptor-operated potassium current in guinea pig atrial myocyte

Basic and Clinical Pharmacology & Toxicology 95, 238 2004年
Impaired gene expreission of β₁-adrenergic receptor, but not stimulatory G-protein Gsα, in rat ventricular myocardium treated with isoproterenol

Biological and Pharmaceutical Bulletin 27(7) 1130 2004年
Amiodarone inhibits sarcolemmal but not mitochondrial K-ATP channels in guinea pig ventricular cells

T Sato, T Takizawa, T Saito, S Kobayashi, Y Hara, H Nakaya

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 307(3) 955-960 2003年12月
Subcellular distribution of ryanodine receptors in the cardiac muscle of carp (Cyprinus carpio)

American Journal Physiology -Regulatory Integrative and Comparative Physiology 285, R601 2003年
Subcellular distribution of ryanodine receptors in the cardiac muscle of carp (Cyprinus carpio)

American Journal Physiology -Regulatory Integrative and Comparative Physiology 285, R601 2003年
Antimalarial drugs inhibit the acetylcholine-receptor-operated potassium current in atrial myocytes

Yukio Hara, Keiichiro Kizaki

Heart Lung and Circulation 11(2) 112-116 2002年
Antimalarial drugs inhibit the acetyl choline-receptor-operated potassium current in aterial myocytes

Heart, Lung and Circulation 11, 112 2002年
Doxorubicin affects the cardiac muscarinic system in the rat

A Chugun, T Uchide, K Temma, RH Kennedy, SV Klimberg, Y Hara, T Sasaki, T Akera

JOURNAL OF VETERINARY MEDICAL SCIENCE 63(12) 1315-1322 2001年12月
Negative inotropic effect of diazepam in isolated guinea pig heart

Y Hara, H Kobayashi, S Ooshiro, K Futamura, T Nishino, A Chugun, K Temma, H Kondo

JOURNAL OF VETERINARY MEDICAL SCIENCE 63(2) 135-143 2001年2月
Glutamate neurotransmission and nitric oxide interaction within the ventrolateral medulla during cardiovascular responses to muscle contraction

T Ishide, Y Hara, TJ Maher, A Ally

BRAIN RESEARCH 874(2) 107-115 2000年8月
Molecular mechanism of doxorubicin-induced anticholinergic effect in guinea-pig atria

Y Hara, K Temma, Z Sekiya, A Chugun, H Kondo

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 78(6) 483-489 2000年6月
Anti-muscarinic actions of mitoxantrone in isolated heart muscles of guinea pigs

European Journal of Pharmacology 407, 183 2000年
Doxorubicin-induced late cardiotoxicity: delayed impairment of Ca²⁺-handling mechanisms in the sarcoplasmic reticulum in the rat

Canadian Journal of Physiology and Pharmacology 78, 329 2000年
抗不整脈薬のK⁺チャネル遮断作用とその電気生理学的意義

中谷晴昭, 小倉武彦, 古澤良恵, 植村展子, 大本由樹, 玉川正次, 渡邊泰秀, 原幸男, 坂下育美, 鈴木俊雄 …

心電図 20(3) 195-201 2000年
Anti-muscarinic actions of mitoxantrone in isolated heart muscles of guinea pigs

European Journal of Pharmacology 407, 183 2000年
Doxorubicin-induced late cardiotoxicity: delayed impairment of Ca^2t-handling mechanisms in the sarcoplasmic reticulum in the rat

Canadian Journal of Physiology and Pharmacology 78, 329 2000年
K⁺ channel blocking action of antiarrhythmic drugs and its pharmacological significance

Japanese Journal of Electrocardiology 20(3) 195 2000年
Biphasic positive inotropic actions of doxorubicin in isolated guinea pig hearts - Relation to Ca2+ release from the sarcoplasmic reticulum

K Temma, A Chugun, Y Hara, T Sasaki, H Kondo

GENERAL PHARMACOLOGY 33(3) 229-236 1999年9月
Diazepam increases calcium sensitivity of the skinned cardiac muscle fiber in guinea pig

Y Hara, A Chugun, K Futamura, T Nishino, H Kondo

JAPANESE JOURNAL OF PHARMACOLOGY 81(1) 122-124 1999年9月

もっとみる

書籍等出版物

1

Modulation of cardiac ATP-sensitive K⁺_-channeles : Potential electrophysiological outcome during myocardial ischemia and reperfusion.

Recent Progress in Electropharmacology of he Heart 1996年

所属学協会

5

共同研究・競争的資金等の研究課題

8