牧野英一 (Hideichi Makino) - マイポータル - researchmap

基本情報

所属: 旧所属愛媛大学医学部医学科教授

学位: 医学博士

J-GLOBAL ID: 200901002406698972
researchmap会員ID: 1000009723

研究キーワード

6

研究分野

2

受賞

1

1990年

日本医師会医学研究助成費

MISC

32

Pathophysiologic phenotypes of Japanese subjects with varying degrees of glucose tolerance: Using the combination of C-peptide secretion rate and minimal model analysis

Y Tokuyama, K Sakurai, K Yagui, N Hashimoto, Y Saito, A Kanatsuka

METABOLISM-CLINICAL AND EXPERIMENTAL 50(7) 812-818 2001年7月
Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse

Y Tang, H Osawa, H Onuma, M Hasegawa, T Nishimiya, M Ochi, H Makino

EUROPEAN JOURNAL OF ENDOCRINOLOGY 145(1) 93-99 2001年7月
Identification of novel C253Y missense and Y864X nonsense mutations in the insulin receptor gene in type A insulin-resistant patients

H Osawa, T Nishimiya, M Ochi, T Niiya, H Onuma, F Kitamuro, Y Kaino, K Kida, H Makino

CLINICAL GENETICS 59(3) 194-197 2001年3月
Mutations in the hepatocyte nuclear factor-4 alpha gene in Japanese with non-insulin-dependent diabetes: A nucleotide substitution in the polypyrimidine tract of intron 1b

K Sakurai, N Seki, R Fujii, K Yagui, Y Tokuyama, F Shimada, H Makino, Y Suzuki, N Hashimoto, Y Saito …

HORMONE AND METABOLIC RESEARCH 32(8) 316-320 2000年8月
Tumor necrosis factor alpha signaling pathway and apoptosis in pancreatic beta cells

N Ishizuka, K Yagui, Y Tokuyama, K Yamada, Y Suzuki, J Miyazaki, N Hashimoto, H Makino, Y Saito, A Kanatsuka

METABOLISM-CLINICAL AND EXPERIMENTAL 48(12) 1485-1492 1999年12月
Effect of ACE gene on diabetic nephropathy in NIDDM patients with insulin resistance

N Kuramoto, T Iizuka, H Ito, K Yagui, M Omura, O Nozaki, T Nishikawa, H Tsuchida, H Makino, Y Saito …

AMERICAN JOURNAL OF KIDNEY DISEASES 33(2) 276-281 1999年2月
A complete defficiency of coagulation factor XIII A-subunit due to a novel compound heterozygote of Ser 413 Leu missense and an nt 389(ins G)frame shift mutations.

Br J Haematiol 107 772-775 1999年
Tang Y, Osawa H, Onuma H, Nishimiya T, Ochi M, ┣DBMakino H(/)-┫DB : Improvement in insulin resitance and the restoration of reduced PDE3B gene expression by piogletazone in adipose tissue of obese, diabetic KKAy mouse. Diabetes

Diabetes 48 1830-1835 1999年
A missense mutation in the CD38 gene, a novel factor for insulin secretion: Association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro

K Yagui, F Shimada, M Mimura, N Hashimoto, Y Suzuki, Y Tokuyama, K Nata, A Tohgo, F Ikehata, S Takasawa …

DIABETOLOGIA 41(9) 1024-1028 1998年9月
Mitogen-activated protein kinase and P70 ribosomal protein S6 kinase are not involved in the insulin-dependent stimulation of cAMP phosphodiesterase kinase in rat adipocytes

Biochim Biophys Acta 1402(2) 197-208 1998年
Insulin enhances macrophage scavenger receptor-mediated endocytotic uptake of advanced glycation end product.

Journal of Biological Chemistry 273(15) 8630-8637 1998年
Expression of human islet amyloid polypeptide amylin impairs insulin secretion in mouse pancreatic beta cells

T Tokuyama, K Yagui, T Yamaguchi, CI Huang, N Kuramoto, F Shimada, J Miyazaki, H Horie, Y Saito, H Makino …

METABOLISM-CLINICAL AND EXPERIMENTAL 46(9) 1044-1051 1997年9月
Detection of an amino acid polymorphism in hormone-sensitive lipase in Japanese subjects

F Shimada, H Makino, N Hashimoto, H Iwaoka, M Taira, O Nozaki, A Kanatsuka, C Holm, D Langin, Y Saito

METABOLISM-CLINICAL AND EXPERIMENTAL 45(7) 862-864 1996年7月
Characterization of the cDNA and gene encoding human PDE3B, the cGIPI isoform of the human cyclic GMP-inhibited cyclic nucleotide phosphodiesterase family

Genomics 36(3) 476-485 1996年
Identification of the aminoacid polymorphisms in hexokinase II in Japanese subjects

F Shimada, N Hashimoto, A Kanatsuka, RL Printz, DK Granner, H Makino

DIABETOLOGIA 39(1) 123-124 1996年1月
FREQUENCY OF MUTATIONS OF INSULIN-RECEPTOR GENE IN JAPANESE PATIENTS WITH NIDDM

M KAN, F KANAI, M IIDA, H JINNOUCHI, M TODAKA, T IMANAKA, K ITO, Y NISHIOKA, T OHNISHI, S KAMOHARA …

DIABETES 44(9) 1081-1086 1995年9月
Insulin resistance associated with decreased levels of insulin receptor mRNA : Evidence of a de novo mutation in the maternal allele

J. Clin. Endocrinol. Metab. 80 1214-1220 1995年
Identification of two novel amino acid polyuorphisms in bete-cell/liver(GLUT2) glucose transporter in Japanese Subjects

Diabetologia 38 211-215 1995年
Identification of two novel amino acid polymorphisms in beta-cell / liver (GLUT 2) gluose transporter in Japanese subjects

Diabetologia 38 211-215 1995年
Roles of ATP in Insulin Action

Annu. Rev. Physiol. 56 273-295 1994年

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