IINO Masamitsu

J-GLOBAL         Last updated: Nov 5, 2018 at 19:02
 
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Name
IINO Masamitsu
URL
http://www.med.nihon-u.ac.jp/department/pharmacology/en/index.html
Affiliation
Nihon University
Section
Division of Cellular and Molecular Pharmacology
Job title
Project Professor
Degree
MD, PhD(Tohoku University)
Research funding number
50133939

Research Areas

 
 

Academic & Professional Experience

 
Apr 2016
 - 
Today
Project Professor, School of Medicine, Nihon University
 
Apr 1995
 - 
Mar 2016
Professor, Graduate School of Medicine, The University of Tokyo
 

Education

 
Apr 1976
 - 
Mar 1980
Graduate School of Medicine, Tohoku University
 
Apr 1970
 - 
Mar 1976
School of Medicine, Tohoku University
 

Awards & Honors

 
Apr 2017
Medal with Purple Ribbon
 
Mar 2013
Setsuro Ebashi Award, Japanese Pharmacological Society
 
Mar 2009
Uehara Prize, The Uehara Memorial Foundation
 

Published Papers

 
Okubo Y, Mikami Y, Kanemaru K, Iino M
Antioxidants & redox signaling   29(12) 1147-1157   Oct 2018   [Refereed]
Okubo Y, Kanemaru K, Suzuki J, Kobayashi K, Hirose K, Iino M
Glia      Oct 2018   [Refereed]
Tainaka K, Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, Iino M, Kasai H, Sasaoka T, Kobayashi K, Miyazono K, Morii E, Isa T, Fukayama M, Kakita A, Ueda HR
Cell reports   24(8) 2196-2210.e9   Aug 2018   [Refereed]
Murayama T, Kurebayashi N, Ishigami-Yuasa M, Mori S, Suzuki Y, Akima R, Ogawa H, Suzuki J, Kanemaru K, Oyamada H, Kiuchi Y, Iino M, Kagechika H, Sakurai T
Molecular pharmacology   94(1) 722-730   Jul 2018   [Refereed]
Ino D, Iino M
Journal of visualized experiments : JoVE   (115)    Sep 2016   [Refereed]
Murakami TC, Mano T, Saikawa S, Horiguchi SA, Shigeta D, Baba K, Sekiya H, Shimizu Y, Tanaka KF, Kiyonari H, Iino M, Mochizuki H, Tainaka K, Ueda HR
Nature neuroscience   21(4) 625-637   Apr 2018   [Refereed]
Ino D, Iino M
Methods in molecular biology (Clifton, N.J.)   1791 287-292   2018   [Refereed]
Ino D, Iino M
Cellular and molecular life sciences : CMLS   74(5) 827-835   Mar 2017   [Refereed]
Murayama T, Kurebayashi N, Ogawa H, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, Oguchi K, Iino M, Sakurai T
Human mutation   37(11) 1231-1241   Nov 2016   [Refereed]
Suzuki J, Kanemaru K, Iino M
Biophysical journal   111(6) 1119-1131   Sep 2016   [Refereed]
Mikami Y, Kanemaru K, Okubo Y, Nakaune T, Suzuki J, Shibata K, Sugiyama H, Koyama R, Murayama T, Ito A, Yamazawa T, Ikegaya Y, Sakurai T, Saito N, Kakizawa S, Iino M
EBioMedicine   11 253-261   Sep 2016   [Refereed]
Kubota J, Mikami Y, Kanemaru K, Sekiya H, Okubo Y, Iino M
The European journal of neuroscience   44(3) 2004-2014   Aug 2016   [Refereed]
Okubo Y, Suzuki J, Kanemaru K, Nakamura N, Shibata T, Iino M
The Journal of neuroscience : the official journal of the Society for Neuroscience   35(48) 15837-15846   Dec 2015   [Refereed]
Ino D, Sagara H, Suzuki J, Kanemaru K, Okubo Y, Iino M
Cell reports   12(12) 1951-1959   Sep 2015   [Refereed]
Murayama T, Kurebayashi N, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, Oguchi K, Iino M, Sakurai T
PloS one   10(6) e0130606   2015   [Refereed]
Kanemaru K, Sekiya H, Xu M, Satoh K, Kitajima N, Yoshida K, Okubo Y, Sasaki T, Moritoh S, Hasuwa H, Mimura M, Horikawa K, Matsui K, Nagai T, Iino M, Tanaka KF
Cell reports   8(1) 311-318   Jul 2014   [Refereed]
Suzuki J, Kanemaru K, Ishii K, Ohkura M, Okubo Y, Iino M
Nature communications   5 4153   Jun 2014   [Refereed]
Kanemaru K, Kubota J, Sekiya H, Hirose K, Okubo Y, Iino M
Proceedings of the National Academy of Sciences of the United States of America   110 11612-11617   Jul 2013   [Refereed]
Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H
Arthritis and rheumatism   65 429-435   Feb 2013   [Refereed]
Kakizawa S, Yamazawa T, Chen Y, Ito A, Murayama T, Oyamada H, Kurebayashi N, Sato O, Watanabe M, Mori N, Oguchi K, Sakurai T, Takeshima H, Saito N, Iino M
The EMBO journal   31 417-428   Jan 2012   [Refereed]
Okubo Y, Kanemaru K, Iino M
Antioxidants & redox signaling   14 1303-1314   Apr 2011   [Refereed]
Okubo Y, Iino M
The Journal of physiology   589 481-488   Feb 2011   [Refereed]
Mashimo M, Okubo Y, Yamazawa T, Yamasaki M, Watanabe M, Murayama T, Iino M
The European journal of neuroscience   32 1668-1677   Nov 2010   [Refereed]
Okubo Y, Sekiya H, Namiki S, Sakamoto H, Iinuma S, Yamasaki M, Watanabe M, Hirose K, Iino M
Proceedings of the National Academy of Sciences of the United States of America   107 6526-6531   Apr 2010   [Refereed]
Iino M
Proceedings of the Japan Academy. Series B, Physical and biological sciences   86 244-256   2010   [Refereed]
Nakamura N, Yamazawa T, Okubo Y, Iino M
Molecular systems biology   5 247   2009   [Refereed]
Iino M
Biochemical and biophysical research communications   369 220-224   Apr 2008   [Refereed]
Yogo T, Urano Y, Mizushima A, Sunahara H, Inoue T, Hirose K, Iino M, Kikuchi K, Nagano T
Proceedings of the National Academy of Sciences of the United States of America   105 28-32   Jan 2008   [Refereed]
Kakizawa S, Moriguchi S, Ikeda A, Iino M, Takeshima H
Cerebellum (London, England)   7 385-391   2008   [Refereed]
Kamikubo Y, Tabata T, Kakizawa S, Kawakami D, Watanabe M, Ogura A, Iino M, Kano M
The Journal of physiology   585 549-563   Dec 2007   [Refereed]
Ikeda A, Miyazaki T, Kakizawa S, Okuno Y, Tsuchiya S, Myomoto A, Saito SY, Yamamoto T, Yamazaki T, Iino M, Tsujimoto G, Watanabe M, Takeshima H
Biochemical and biophysical research communications   363 835-839   Nov 2007   [Refereed]
Kina S, Tezuka T, Kusakawa S, Kishimoto Y, Kakizawa S, Hashimoto K, Ohsugi M, Kiyama Y, Horai R, Sudo K, Kakuta S, Iwakura Y, Iino M, Kano M, Manabe T, Yamamoto T
The European journal of neuroscience   26 2269-2278   Oct 2007   [Refereed]
Uemura T, Kakizawa S, Yamasaki M, Sakimura K, Watanabe M, Iino M, Mishina M
The Journal of neuroscience : the official journal of the Society for Neuroscience   27 12096-12108   Oct 2007   [Refereed]
Kanemaru K, Okubo Y, Hirose K, Iino M
The Journal of neuroscience : the official journal of the Society for Neuroscience   27 8957-8966   Aug 2007   [Refereed]
Kakizawa S, Kishimoto Y, Hashimoto K, Miyazaki T, Furutani K, Shimizu H, Fukaya M, Nishi M, Sakagami H, Ikeda A, Kondo H, Kano M, Watanabe M, Iino M, Takeshima H
The EMBO journal   26 1924-1933   Apr 2007   [Refereed]
Namiki S, Sakamoto H, Iinuma S, Iino M, Hirose K
The European journal of neuroscience   25 2249-2259   Apr 2007   [Refereed]
Iino M
Advances in experimental medicine and biology   592 305-312   2007   [Refereed]
Hashido M, Hayashi K, Hirose K, Iino M
EMBO reports   7 1117-1123   Nov 2006   [Refereed]
Baba Y, Hayashi K, Fujii Y, Mizushima A, Watarai H, Wakamori M, Numaga T, Mori Y, Iino M, Hikida M, Kurosaki T
Proceedings of the National Academy of Sciences of the United States of America   103 16704-16709   Nov 2006   [Refereed]
Furutani K, Okubo Y, Kakizawa S, Iino M
Proceedings of the National Academy of Sciences of the United States of America   103 8528-8533   May 2006   [Refereed]
Ishii K, Hirose K, Iino M
EMBO reports   7 390-396   Apr 2006   [Refereed]
Iino M
Journal of pharmacological sciences   100 538-544   2006   [Refereed]
Kakizawa S, Miyazaki T, Yanagihara D, Iino M, Watanabe M, Kano M
Proceedings of the National Academy of Sciences of the United States of America   102 19180-19185   Dec 2005   [Refereed]
Namiki S, Kakizawa S, Hirose K, Iino M
The Journal of physiology   566 849-863   Aug 2005   [Refereed]
Hashimoto A, Hirose K, Iino M
The Journal of biological chemistry   280 26225-26232   Jul 2005   [Refereed]
Hayakawa Y, Nemoto T, Iino M, Kasai H
Cell calcium   37 359-370   Apr 2005   [Refereed]
Ueda HR, Hayashi S, Chen W, Sano M, Machida M, Shigeyoshi Y, Iino M, Hashimoto S
Nature genetics   37 187-192   Feb 2005   [Refereed]
Yamada A, Hirose K, Hashimoto A, Iino M
The Biochemical journal   385 589-594   Jan 2005   [Refereed]
Okubo Y, Kakizawa S, Hirose K, Iino M
The Journal of neuroscience : the official journal of the Society for Neuroscience   24 9513-9520   Oct 2004   [Refereed]
Ueda HR, Chen W, Minami Y, Honma S, Honma K, Iino M, Hashimoto S
Proceedings of the National Academy of Sciences of the United States of America   101 11227-11232   Aug 2004   [Refereed]
Yogo T, Kikuchi K, Inoue T, Hirose K, Iino M, Nagano T
Chemistry & biology   11 1053-1058   Aug 2004   [Refereed]
Ueda HR, Hayashi S, Matsuyama S, Yomo T, Hashimoto S, Kay SA, Hogenesch JB, Iino M
Proceedings of the National Academy of Sciences of the United States of America   101 3765-3769   Mar 2004   [Refereed]
Shirane D, Sugao K, Namiki S, Tanabe M, Iino M, Hirose K
Nature genetics   36 190-196   Feb 2004   [Refereed]
Uchino M, Sakai N, Kashiwagi K, Shirai Y, Shinohara Y, Hirose K, Iino M, Yamamura T, Saito N
The Journal of biological chemistry   279 2254-2261   Jan 2004   [Refereed]
Eto K, Yamashita T, Hirose K, Tsubamoto Y, Ainscow EK, Rutter GA, Kimura S, Noda M, Iino M, Kadowaki T
American journal of physiology. Endocrinology and metabolism   285 E262-71   Aug 2003   [Refereed]
Tomida T, Hirose K, Takizawa A, Shibasaki F, Iino M
The EMBO journal   22 3825-3832   Aug 2003   [Refereed]
Tu H, Nosyreva E, Miyakawa T, Wang Z, Mizushima A, Iino M, Bezprozvanny I
Biophysical journal   85 290-299   Jul 2003   [Refereed]
Namiki S, Tomida T, Tanabe M, Iino M, Hirose K
Biochemical and biophysical research communications   305 592-597   Jun 2003   [Refereed]
Inoue T, Kikuchi K, Hirose K, Iino M, Nagano T
Chemistry & biology   10 503-509   Jun 2003   [Refereed]
Kakizawa S, Yamada K, Iino M, Watanabe M, Kano M
The European journal of neuroscience   17 545-554   Feb 2003   [Refereed]
Noda M, Yamashita S, Takahashi N, Eto K, Shen LM, Izumi K, Daniel S, Tsubamoto Y, Nemoto T, Iino M, Kasai H, Sharp GW, Kadowaki T
The Journal of biological chemistry   277 41817-41826   Nov 2002   [Refereed]
Nosyreva E, Miyakawa T, Wang Z, Glouchankova L, Mizushima A, Iino M, Bezprozvanny I
The Biochemical journal   365 659-667   Aug 2002   [Refereed]
Iino M
The Journal of physiology   542 667   Aug 2002   [Refereed]
Ueda HR, Hirose K, Iino M
Journal of theoretical biology   216 501-512   Jun 2002   [Refereed]
Ueda HR, Matsumoto A, Kawamura M, Iino M, Tanimura T, Hashimoto S
The Journal of biological chemistry   277 14048-14052   Apr 2002   [Refereed]
Tu H, Miyakawa T, Wang Z, Glouchankova L, Iino M, Bezprozvanny I
Biophysical journal   82 1995-2004   Apr 2002   [Refereed]
Mori Y, Wakamori M, Miyakawa T, Hermosura M, Hara Y, Nishida M, Hirose K, Mizushima A, Kurosaki M, Mori E, Gotoh K, Okada T, Fleig A, Penner R, Iino M, Kurosaki T
The Journal of experimental medicine   195 673-681   Mar 2002   [Refereed]
Nakanishi W, Kikuchi K, Inoue T, Hirose K, Iino M, Nagano T
Bioorganic & medicinal chemistry letters   12 911-913   Mar 2002   [Refereed]
Oyamada H, Oguchi K, Saitoh N, Yamazawa T, Hirose K, Kawana Y, Wakatsuki K, Oguchi K, Tagami M, Hanaoka K, Endo M, Iino M
Japanese journal of pharmacology   88 159-166   Feb 2002   [Refereed]
Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.
Eto K, Yamashita T, Tsubamoto Y, Terauchi Y, Hirose K, Kubota N, Yamashita S, Taka J, Satoh S, Sekihara H, Tobe K, Iino M, Noda M, Kimura S, Kadowaki T
Diabetes   51 87-97   Jan 2002   [Refereed]
Molecular basis and physiological functions of dynamic Ca2+ signalling in smooth muscle cells.
Iino M
Novartis Foundation symposium   246 142-6; discussion 147   2002   [Refereed]
Matsuzaki M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H
Nature neuroscience   4 1086-1092   Nov 2001   [Refereed]
Namiki S, Hirose K, Iino M
Biochemical and biophysical research communications   288 798-804   Nov 2001   [Refereed]
Reduced IP3 sensitivity of IP3 receptor in Purkinje neurons.
Fujiwara A, Hirose K, Yamazawa T, Iino M
Neuroreport   12 2647-2651   Aug 2001   [Refereed]
Miyakawa T, Mizushima A, Hirose K, Yamazawa T, Bezprozvanny I, Kurosaki T, Iino M
The EMBO journal   20 1674-1680   Apr 2001   [Refereed]
Nemoto T, Kimura R, Ito K, Tachikawa A, Miyashita Y, Iino M, Kasai H
Nature cell biology   3 253-258   Mar 2001   [Refereed]
Negative control of store-operated Ca2+ influx by B cell receptor cross-linking.
Hashimoto A, Hirose K, Kurosaki T, Iino M
Journal of immunology (Baltimore, Md. : 1950)   166 1003-1008   Jan 2001   [Refereed]
Inoue T, Kikuchi K, Hirose K, Iino M, Nagano T
Chemistry & biology   8 9-15   Jan 2001   [Refereed]
Nagai Y, Miyazaki M, Aoki R, Zama T, Inouye S, Hirose K, Iino M, Hagiwara M
Nature biotechnology   18 313-316   Mar 2000   [Refereed]
Iino M
Japanese journal of pharmacology   82 15-20   Jan 2000   [Refereed]
Dynamic Ca2+ signalling in rat arterial smooth muscle cells under the control of local renin-angiotensin system.
Asada Y, Yamazawa T, Hirose K, Takasaka T, Iino M
The Journal of physiology   521 Pt 2 497-505   Dec 1999   [Refereed]
Nishi M, Komazaki S, Kurebayashi N, Ogawa Y, Noda T, Iino M, Takeshima H
The Journal of cell biology   147 1473-1480   Dec 1999   [Refereed]
Iino M
The Japanese journal of physiology   49 325-333   Aug 1999   [Refereed]
Inoue T, Kikuchi K, Hirose K, Iino M, Nagano T
Bioorganic & medicinal chemistry letters   9 1697-1702   Jun 1999   [Refereed]
Hirose K, Kadowaki S, Tanabe M, Takeshima H, Iino M
Science (New York, N.Y.)   284 1527-1530   May 1999   [Refereed]
Hashimoto A, Hirose K, Okada H, Kurosaki T, Iino M
The Journal of biological chemistry   274 11203-11208   Apr 1999   [Refereed]
Miyakawa T, Maeda A, Yamazawa T, Hirose K, Kurosaki T, Iino M
The EMBO journal   18 1303-1308   Mar 1999   [Refereed]
Hirabayashi T, Kume K, Hirose K, Yokomizo T, Iino M, Itoh H, Shimizu T
The Journal of biological chemistry   274 5163-5169   Feb 1999   [Refereed]
Iino M
Molecular and cellular biochemistry   190 185-190   Jan 1999   [Refereed]
Komazaki S, Ikemoto T, Takeshima H, Iino M, Endo M, Nakamura H
Cell and tissue research   294 467-473   Dec 1998   [Refereed]
Ikemoto T, Takeshima H, Iino M, Endo M
Pflugers Archiv : European journal of physiology   437 43-48   Dec 1998   [Refereed]
Role of the inositol phosphatase SHIP in B cell receptor-induced Ca2+ oscillatory response.
Okada H, Bolland S, Hashimoto A, Kurosaki M, Kabuyama Y, Iino M, Ravetch JV, Kurosaki T
Journal of immunology (Baltimore, Md. : 1950)   161 5129-5132   Nov 1998   [Refereed]
Nishi M, Komazaki S, Iino M, Kangawa K, Takeshima H
FEBS letters   432 191-196   Aug 1998   [Refereed]
Shimuta M, Komazaki S, Nishi M, Iino M, Nakagawara K, Takeshima H
FEBS letters   431 263-267   Jul 1998   [Refereed]
Takeshima H, Komazaki S, Hirose K, Nishi M, Noda T, Iino M
The EMBO journal   17 3309-3316   Jun 1998   [Refereed]
Mitsugumin29, a novel synaptophysin family member from the triad junction in skeletal muscle.
Takeshima H, Shimuta M, Komazaki S, Ohmi K, Nishi M, Iino M, Miyata A, Kangawa K
The Biochemical journal   331 ( Pt 1) 317-322   Apr 1998   [Refereed]
Hirose K, Kadowaki S, Iino M
The Journal of physiology   506 ( Pt 2) 407-414   Jan 1998   [Refereed]
Kasai Y, Yamazawa T, Sakurai T, Taketani Y, Iino M
The Journal of physiology   504 ( Pt 2) 349-357   Oct 1997   [Refereed]

Misc

 
Iino, M.
Biochem. Biophys. Res. Commun.   142(1) 47-52   1987
Calcium induced calcium release mechanism in guinea-pig taenia caeci.
Iino, M.
J. Gen. Physiol.   94 363-383   1989
Biphasic Ca2+ dependence of inositol 1,4,5-trisphosphate-induced Ca release in smooth muscle cells of the guinea pig taenia caeci.
Iino, M.
J. Gen. Physiol.   95 1103-1122   1990
Effects of adenine nucleotides on inositol 1,4,5-trisphosphate-induced calcium release in vascular smooth muscle cells.
Iino, M.
J. Gen. Physiol.   98 681-698   1991

Books etc

 
Some properties of chemically skinned smooth muscle fibers.
Elsevier : Amsterdam.   1977   
Effect of "viscosity" of the medium on mechanical properties of skinned skeletal muscle fibers.
University of Tokyo Press : Tokyo.   1978   
Mechanism of calcium release from intracellular calcium store.
Japan Science Press : Tokyo.   1988   
A possible potentiating effect of inorganic phosphate on tension production in skinned skeletal muscle fibers.
Alan R. Liss, Inc. : New York.   1989   
Calcium release from the intracellular store in smooth muscle cells.
Elsevier : Amsterdam.   1989   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(S))
Project Year: 2005 - 2009    Investigator(s): Masamitsu IINO
Ca^<2+> makes bones strong but is also a "switch" for cellular functions. We studied the switching mechanism of Ca^<2+> in the brain and other tissues making use of imaging methods to visualize the switching events. We found new Ca^<2+> switch-dep...
Regulation of central nervous system functions by Ca2+ signaling mechanism.
Kinetics of Ca2+ release from inositol 1,4,5-trisphosphate seusitive Ca2+ stores