平田恭信 (Yasunobu Hirata) - マイポータル - researchmap

基本情報

所属: 東京大学医学部附属病院循環器内科助教授

学位: 医学博士(東京大学)

J-GLOBAL ID: 200901096319855004
researchmap会員ID: 1000011134

研究キーワード

6

研究分野

3

委員歴

5

受賞

2

1993年

東京都医師会医学研究賞
1985年

日本心臓財団賞

MISC

73

Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a p21(WAF1)-dependent pathway

M Sata, A Takahashi, K Tanaka, M Washida, N Ishizaka, J Ako, M Yoshizumi, Y Ouchi, T Taniguchi, Y Hirata …

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 22(8) 1305-1309 2002年8月
Angiotensin II induces myocyte enhancer factor 2-and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes

E Suzuki, H Nishimatsu, H Satonaka, K Walsh, A Goto, M Omata, T Fujita, R Nagai, Y Hirata

CIRCULATION RESEARCH 90(9) 1004-1011 2002年5月
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage

H Mitani, N Ishizaka, T Aizawa, M Ohno, S Usui, T Suzuki, T Amaki, Mori, I, Y Nakamura, M Sato …

HYPERTENSION 39(4) 838-843 2002年4月
Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury - Studies on transgenic/knockout mice of adrenomedullin gene

H Nishimatsu, Y Hirata, T Shindo, H Kurihara, M Kakoki, D Nagata, H Hayakawa, H Satonaka, M Sata, A Tojo …

CIRCULATION RESEARCH 90(6) 657-663 2002年4月
Constitutive activation of proto-oncogen protein p21 induces cell cycle arrest in the G1 phase in contact-inhibited vascular endothelial cells.

Hypertens Res 25:773-8 2002年
Urinary free fatty acids bound to albumin aggravate tubulointerstitial damage.

Kidney Int 62:1628-37 2002年
G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells.

Biochem Biophys Res Commun 297:1058-61 2002年
Kruppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

Nat Med 8:856-63 2002年
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis.

Nat Med 8:403-409 2002年
Orthogonality of calcium concentration and ability of 4,5-diaminofluorescein (DAF-2) to detect NO.

J Biol Chem 277:47-49 2002年
Acute and chronic smooth muscle cell apoptosis after mechanical vascular injury can occur independently of the fas-death pathway.

Arterioscler Thromb Vasc Biol 21:1733-1737 2001年
Elevated Sympathetic Nervous Activity in Mice Deficient in CGRP.

Circ Res 89:983-990 2001年
Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene.

Circulation 104:1964-1971 2001年
Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia.

FASEB J 15:2530-2532 2001年
Adrenomedullin Induces Endothelium-Dependent Vasorelaxation via the Phosphatidylinositol 3 Kinase/Akt-Dependent Pathway in Rat Aorta.

Circ Res 89:63-70 2001年
Measurement of plasma brain natriuretic peptide level as a guide for cardiac overload.

Cardiovasc Res 51:585-591 2001年
Circulating smooth muscle progenitor cells contribute to atherosclerosis.

Nature Med 7:382-383 2001年
Bioimaging of nitric oxide with fluorescent indicators based on rhodamine chromophore.

Anal Chem 73:1967-1973 2001年
Crucial Role of Type 1, but Not Type 3, Inositol 1,4,5-Trisphosphate (IP3) Receptors in IP3-Induced Ca2+ Release, Capacitative Ca2+ Entry, and Proliferation of A7r5 Vascular Smooth Muscle Cells.

Circ Res 88:202-209 2001年
Transcriptional activation of the cyclin D1 gene is mediated by multiple cis elements including SP1 sites and a cyclic AMP responsive element in vascular endothelial cells.

J Biol Chem 276:662-669 2001年

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所属学協会

9

共同研究・競争的資金等の研究課題

4