滝澤始 (Hajime Takizawa) - マイポータル - researchmap

基本情報

所属: 帝京大学医学部附属溝口病院教授,教授

学位: 医学博士(東京大学)
Doctor of Philosophy, PhD

J-GLOBAL ID: 200901078432168201
researchmap会員ID: 1000011155

研究キーワード

3

研究分野

3

学歴

2

- 1979年

東京大学, 医学部, 医学科
- 1979年

東京大学

受賞

6

MISC

61

Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice

Ying Ji Li, Hajime Takizawa, Arata Azuma, Tadashi Kohyama, Yasuhiro Yamauchi, Satoru Takahashi, Masayuki Yamamoto, Tomoyuki Kawada, Shoji Kudoh, Isamu Sugawara

CLINICAL IMMUNOLOGY 128(3) 366-373 2008年9月
Clinical implications of the immunomodulatory effects of macrolides.

Tamaoki J, Kadota J, Takizawa H

Am J Med. 117(9A) 5S-11S 2004年
Effects of diesel exhaust on murine alveolar macrophages and a macrophage cell line.

Exp Lung Res 28(3):201-17 2002年
PDE4 inhibitors attenuate fibroblast chemotaxis and contraction of native collagen gels.

Am J Respir Cell Mol Biol 26(6):694-701 2002年
Interferon-gamma inhibits hepatocyte growth factor-stimulated cell proliferation of human bronchial epithelial cells: upregulation of p27(kip1) cyclin-dependent kinase inhibitor.

Am. J. Respir. Cell Mol. Biol. 26:231-238 2002年
Increased expression of transforming growth factor-beta 1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD)

H Takizawa, M Tanaka, K Takami, T Ohtoshi, K Ito, M Satoh, Y Okada, F Yamasawa, K Nakahara, A Umeda

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 163(6) 1476-1483 2001年5月
Increased Expression of Transforming Growth Factor-β1 in Small Airway Epithelium from Tobacco Smokers and patients with Chronic Obstructive Pulmonary Disease(COPD). (Academic Journal,2001)

Am. J Respir Crit Care Med. 163 1476-1483 2001年
Benzene-extracted components are important for the major activity of diesel exhaust particles(DEP) : Effect on IL-8 gene expression in human bronchial epithelial cells. (Academic Journal,)

Am J Respire Cell Mol Biol. 24 419-426 2001年
Intervention of TARC Attenuates The Development of Allergic Airway Inflammation and Hyperresponsiveness in Mice.

J Immunol. (Academic Journal,) 166 2055-2062 2001年
Intervention of TARC Attenuates The Development of Allergic Airway Inflammation and Hyperresponsiveness in Mice.

J Immunol. 166 2055-2062 2001年
Benzene-extracted components are important for the major activity of diesel exhaust particles(DEP) : Effect on IL-8 gene expression in human bronchial epithelial cells.

Am J Respire Cell Mol Biol. 24 419-426 2001年
Adult-to-adult living-related liver transplantation for hepatitis B-related cirrhosis in Japan: Two case reports

Y Kita, Y Harihara, M Hirata, K Kusaka, K Sano, M Mori, M Ito, H Yoshino, A Nakao, H Takizawa …

TRANSPLANTATION PROCEEDINGS 32(7) 2189-2192 2000年11月
Nuclear factor-kappa B activation in silica-induced interleukin 8 production by human bronchial epithelial cells

M Desaki, H Takizawa, T Kasama, K Kobayashi, Y Morita, K Yamamoto

CYTOKINE 12(8) 1257-1260 2000年8月
Diesel exhaust particles up-regulate expression of intercellular adhesion molecule-1 (ICAM-1) in human bronchial epithelial cells

H Takizawa, S Abe, T Ohtoshi, S Kawasaki, K Takami, M Desaki, Sugawara, I, S Hashimoto, A Azuma, K Nakahara …

CLINICAL AND EXPERIMENTAL IMMUNOLOGY 120(2) 356-362 2000年5月
Diesel exhaust particles activate p38 MAP kinase to produce IL-8 and RANTES by human bronchial epithelial cells and N-acetyl cysteine attenuates p38 MAP kinase activation. (Academic Journal,

Am. J. Respir. Crit. Care Med. 161 280-285 2000年
Erythromycin suppresses unclear factor-kappa B and activatior protein-1 activation in human bronchial epithelial cells. (Academic Journal,)

DESAKI M, TAKIZAWA H, OHTOSHI T, KASAMA T, KOBAYASHI K, SUNAZUKA T, OMURA S, YAMAMOTO K, ITO K

Biochem. Biophys. Res. Commun. 267(1) 124-128 2000年
Nuclear factor-kappa B activation in silica-induced interleukin 8 production by human bronchial epithelial cells. (Academic Journal,)

DESAKI M, TAKIZAWA H, KASAMA T, KOBAYASHI K, MORITA Y, YAMAMOTO K

Cytokine. 12(8) 1257-1260 2000年
Diesel exhausts(DE)induced cytokine expression in human bronchial epithelial cells : A study with a new cell exposure system to freshly generated diesel exhaust in vitro. (Academic Journal,

Am. J. Respir. Cell Mol. Biol. 22 296-303 2000年
Increased expression of inflammatory mediators in small airway epithelium from tobacco smokers. (Academic Journal,)

Am. J. Physiol. 278 L906-L913 2000年
Increased expression of inflammatory mediators in small airway epithelium from tobacco smokers.

Am. J. Physiol. 278 L906-L913 2000年

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書籍等出版物

5

講義録呼吸器学

メジカルビュー社 2004年
慢性気道炎症と気道上広細胞-リモデリングを含めて-

アレルギー炎症性疾患-新たなアプローチ- 1994年
Airway epithelial cells in chronic airway inflammation-including remodelling processes

Allergic Inflammatory Diseases 1994年
リウマチ性疾患の肺病変( in(/)-リウマチ学)

同文書院 1989年
Pulmonary involvement of rheumatic diseases

1989年

所属学協会

8

共同研究・競争的資金等の研究課題

9