竹原和彦 (Kazuhiko Takehara) - マイポータル

基本情報

所属: 金沢大学医学系教授

学位: 医学博士(東京大学)

J-GLOBAL ID: 200901070411056186
researchmap会員ID: 1000011226

外部リンク: http://web.kanazawa-u.ac.jp/~med24/

研究キーワード

研究分野

ライフサイエンス / 皮膚科学 /

経歴

学歴

- 1979年

東京大学, 医学部, 医学科
- 1979年

東京大学

委員歴

受賞

1998年

第32回三井生命厚生事業団医学研究助成
1997年

平成9年度北陸製薬・アレルギー学術奨励賞

論文

Attenuation of murine sclerodermatous models by the selective S1P<inf>1</inf> receptor modulator cenerimod

Miyu Kano, Tadahiro Kobayashi, Mutsumi Date, Momoko Tennichi, Yasuhito Hamaguchi, Daniel S. Strasser, Kazuhiko Takehara, Takashi Matsushita

Scientific Reports 9(1) 658 2019年12月1日査読有り
A case of juvenile localized scleroderma with anti-topoisomerase I antibody

Kyoko Shimizu, Takashi Matsushita, Kazuhiko Takehara, Yasuhito Hamaguchi

European Journal of Dermatology 29(4) 443-444 2019年7月1日査読有り
A case of dermatomyositis with the anti-signal recognition particle antibody that was successfully treated with prednisolone and intravenous immunoglobulin therapy

Kie Mizumaki, Shintaro Maeda, Yuka Ikawa, Takashi Matsushita, Kazuhiko Takehara, Yasuhito Hamaguchi

Journal of Dermatology 46(7) e251-e253 2019年7月査読有り
Increased expression levels of FcγRIIB on naïve and double-negative memory B cells in patients with systemic sclerosis.

Yagi-Numata N, Matsushita T, Takehara K, Hamaguchi Y

Clinical and experimental rheumatology 37(4) 23-31 2019年7月1日査読有り
Regulatory B1a Cells Suppress Melanoma Tumor Immunity via IL-10 Production and Inhibiting T Helper Type 1 Cytokine Production in Tumor-Infiltrating CD8⁺ T Cells

Tadahiro Kobayashi, Kyosuke Oishi, Ai Okamura, Shintaro Maeda, Akito Komuro, Yasuhito Hamaguchi, Manabu Fujimoto, Kazuhiko Takehara, Takashi Matsushita

Journal of Investigative Dermatology 139(7) 1535-1544.e1 2019年7月査読有り
Long-term follow-up of finger passive range of motion in Japanese systemic sclerosis patients treated with self-administered stretching

Naoki Mugii, Takashi Matsushita, Sachie Oohata, Hirokazu Okita, Tetsutarou Yahata, Fujiko Someya, Minoru Hasegawa, Manabu Fujimoto, Kazuhiko Takehara, Yasuhito Hamaguchi

Modern Rheumatology 29(3) 484-490 2019年5月4日査読有り
Soluble CD163 is a potential biomarker in systemic sclerosis

Takashi Matsushita, Kazuhiko Takehara

Expert Review of Molecular Diagnostics 19(3) 197-199 2019年3月4日査読有り
Diagnostic criteria, severity classification and guidelines of eosinophilic fasciitis.

Masatoshi Jinnin, Toshiyuki Yamamoto, Yoshihide Asano, Osamu Ishikawa, Shinichi Sato, Kazuhiko Takehara, Minoru Hasegawa, Manabu Fujimoto, Hironobu Ihn

The Journal of dermatology 45(8) 881-890 2018年8月査読有り
Diagnostic criteria, severity classification and guidelines of lichen sclerosus et atrophicus.

Minoru Hasegawa, Osamu Ishikawa, Yoshihide Asano, Shinichi Sato, Masatoshi Jinnin, Kazuhiko Takehara, Manabu Fujimoto, Toshiyuki Yamamoto, Hironobu Ihn

The Journal of dermatology 45(8) 891-897 2018年8月査読有り
Angiosarcoma-related pneumohemothorax treated with intrapleural paclitaxel administration and pleurodesis with OK-432.

Oishi K, Kitano T, Mizumaki K, Maeda S, Saito D, Yoshida S, Matsumoto I, Takehara K, Hamaguchi Y

European journal of dermatology : EJD 28(4) 520-521 2018年8月査読有り
Increased interleukin-9 levels in sera, muscle and skin of patients with dermatomyositis

Kyosuke Oishi, Takashi Matsushita, Kazuhiko Takehara, Yasuhito Hamaguchi

Journal of Dermatology 45(8) 1023-1025 2018年8月査読有り
BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance

Takashi Matsushita, Tadahiro Kobayashi, Kie Mizumaki, Miyu Kano, Tomoyo Sawada, Momoko Tennichi, Ai Okamura, Yasuhito Hamaguchi, Yoichiro Iwakura, Minoru Hasegawa …

Science Advances 4(7) eaas9944 2018年7月11日査読有り
Diagnostic criteria, severity classification and guidelines of localized scleroderma.

Yoshihide Asano, Manabu Fujimoto, Osamu Ishikawa, Shinichi Sato, Masatoshi Jinnin, Kazuhiko Takehara, Minoru Hasegawa, Toshiyuki Yamamoto, Hironobu Ihn

The Journal of dermatology 45(7) 755-780 2018年7月査読有り
Diagnostic criteria, severity classification and guidelines of systemic sclerosis.

Yoshihide Asano, Masatoshi Jinnin, Yasushi Kawaguchi, Masataka Kuwana, Daisuke Goto, Shinichi Sato, Kazuhiko Takehara, Masaru Hatano, Manabu Fujimoto, Naoki Mugii …

The Journal of dermatology 45(6) 633-691 2018年6月査読有り
Impact of a new simplified disability scoring system for adult patients with localized scleroderma.

Naoko Okiyama, Yoshihide Asano, Yasuhito Hamaguchi, Masatoshi Jinnin, Sei-Ichiro Motegi, Haruka Koizumi, Minoru Hasegawa, Osamu Ishikawa, Shinichi Sato, Kazuhiko Takehara …

The Journal of dermatology 45(4) 431-435 2018年4月査読有り
Food-dependent exercise-induced anaphylaxis due to shrimp associated with 43 kDa, a new antigen.

Kimura H, Inami M, Hamaguchi Y, Takehara K, Akimoto S, Yokooji T, Matsuo H, Matsushita T

The Journal of dermatology 45(3) 366-367 2018年3月査読有り
An update on biomarker discovery and use in systemic sclerosis

Takashi Matsushita, Kazuhiko Takehara

Expert Review of Molecular Diagnostics 17(9) 823-833 2017年9月2日査読有り
RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis.

Oka A, Asano Y, Hasegawa M, Fujimoto M, Ishikawa O, Kuwana M, Kawaguchi Y, Yamamoto T, Takahashi H, Goto D …

The Journal of investigative dermatology 137(9) 1878-1886 2017年9月査読有り
Case of anti-transcriptional intermediary factor-1-positive dermatomyositis associated with breast cancer developing over 10 years

Takashi Matsushita, Kouhei Takehara, Kyosuke Oishi, Shintaro Maeda, Yasuhito Hamaguchi, Satoko Ishikawa, Masafumi Inokuchi, Yoshio Michiwa, Kazuhiko Takehara

JOURNAL OF DERMATOLOGY 44(8) 972-973 2017年8月査読有り
Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis.

Chikashi Terao, Takahisa Kawaguchi, Philippe Dieude, John Varga, Masataka Kuwana, Marie Hudson, Yasushi Kawaguchi, Marco Matucci-Cerinic, Koichiro Ohmura, Gabriela Riemekasten …

Annals of the rheumatic diseases 76(6) 1150-1158 2017年6月査読有り

もっとみる

MISC

319

Bosentan increases serum IL-12 levels in systemic sclerosis patients with pulmonary arterial hypertension

Yasuhito Hamaguchi, Manabu Fujimoto, Minoru Hasegawa, Takashi Matsushita, Kazuhiko Takehara

Journal of Dermatological Science 55(1) 66-67 2009年7月
Role of Connective Tissue Growth Factor and its Interaction With Basic Fibroblast Growth Factor and Macrophage Chemoattractant Protein-1 in Skin Fibrosis

Sonoko Chujo, Fumiaki Shirasaki, Miki Kondo-Miyazaki, Yuka Ikawa, Kazuhiko Takehara

JOURNAL OF CELLULAR PHYSIOLOGY 220(1) 189-195 2009年7月
Reduced red blood cell velocity in nail-fold capillaries as a sensitive and specific indicator of microcirculation injury in systemic sclerosis

Naoki Mugii, Minoru Hasegawa, Yasuhito Hamaguchi, Chihiro Tanaka, Kenzo Kaji, Kazuhiro Komura, Ikuko Ueda-Hayakawa, Sho Horie, Munehiro Ikuta, Katsuhiko Tachino …

RHEUMATOLOGY 48(6) 696-703 2009年6月
Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-beta-induced mouse fibrosis

Yuka Ikawa, Poh-Sing Ng, Koki Endo, Miki Kondo, Sonoko Chujo, Wataru Ishida, Fumiaki Shirasaki, Manabu Fujimoto, Kazuhiko Takehara

JOURNAL OF CELLULAR PHYSIOLOGY 216(3) 680-687 2008年9月
The loss of MCP-1 attenuates cutaneous ischemia-reperfusion injury in a mouse model of pressure ulcer

Yuki Saito, Minoru Hasegawa, Manabu Fujimoto, Takashi Matsushita, Mayuka Horikawa, Motoi Takenaka, Fumihide Ogawa, Junko Sugama, Douglas A. Steeber, Shinichi Sato …

Journal of Investigative Dermatology 128(7) 1838-1851 2008年7月
Bullous pemphigoid with a prolonged prodrome

Tomomi Nakatani, Makoto Inaoki, Kazuhiko Takehara

JOURNAL OF DERMATOLOGY 35(7) 433-436 2008年7月
Elevated serum levels of APRIL, but not BAFF, in patients with atopic dermatitis

Takashi Matsushita, Manabu Fujimoto, Takeshi Echigo, Yukiyo Matsushita, Yuka Shimada, Minoru Hasegawa, Kazuhiko Takehara, Shinichi Sato

Experimental Dermatology 17(3) 197-202 2008年3月
強皮症の原因はどこまで解明されたか

感染・炎症・免疫 38,60-62, 2008 2008年
強皮症のすべてがわかる本

保健同人社 2008年
Antiphospholipid antibodies in patients with autoimmune blistering disease

Takeshi Echigo, Minoru Hasegawa, Makoto Inaoki, Masahide Yamazaki, Shinichi Sato, Kazuhiko Takehara

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 57(3) 397-400 2007年9月
強皮症治療薬

皮膚科の臨床 49,1201-1205 2007年
強皮症

綜合臨床 14,314-315 2007年
Elevated serum levels of APRIL, but not BAFF, in patients with atopic dermatitis

JOURNAL OF RHEUMATOLOGY 34(10) 2056-62 2007年
Clinical evaluation of anti-aminoacyl tRNA synthetase antibodies in Japanese patients with dermatomyositis

JOURNAL OF RHEOLOGY 34(5) 1012-8 2007年
Elevated serum levels of APRIL, but not BAFF, in patients with atopic dermatitis

JOURNAL OF RHEUMATOLOGY 34(10) 2056-62 2007年
Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: An association with malignancy

K. Kaji, M. Fujimoto, M. Hasegawa, M. Kondo, Y. Saito, K. Komura, T. Matsushita, H. Orito, Y. Hamaguchi, K. Yanaba …

Rheumatology 46(1) 25-28 2007年1月
Clinical evaluation of anti-aminoacyl tRNA synthetase antibodies in Japanese patients with dermatomyositis

JOURNAL OF RHEOLOGY 34(5) 1012-8 2007年
Antiphospholipid antibodies in patients with autoimmune blistering disease

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 57(3) 397-400 2007年
Reactive hemophagocytic syndrome in a patient with polyarteritis nodosa associated with Epstein-Barr virus reactivation

Hayakawa, I, F Shirasaki, H Ikeda, N Oishi, M Hasegawa, S Sato, K Takehara

RHEUMATOLOGY INTERNATIONAL 26(6) 573-576 2006年4月
Lymphatic mapping and sentinel lymph node biopsy for staging of aggressive digital papillary adenocarcinoma

R Morita, N Hatta, F Shirasaki, Hayakawa, I, N Ohishi, K Takehara

PLASTIC AND RECONSTRUCTIVE SURGERY 117(2) 710-712 2006年2月

もっとみる

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

全身性強皮症におけるEffector B細胞の役割について検討

日本学術振興会科学研究費助成事業 2017年4月 - 2020年3月

竹原和彦
細胞成長因子

科学研究費補助金 1987年
抗核抗体

科学研究費補助金 1987年
強皮症

科学研究費補助金 1987年
Growth factor

Grant-in-Aid for Scientific Research 1987年
Antinuclear antibody

Grant-in-Aid for Scientific Research 1987年
Scleroderma

Grant-in-Aid for Scientific Research 1987年