Tomihiko Higuti - My portal - researchmap

Profile Information

Affiliation: Former Institution / Organization The University of Tokushima Faculty of Pharmaceutical Sciences School of Pharmacy

Degree: (BLANK)(Osaka University)

J-GLOBAL ID: 200901043523410805
researchmap Member ID: 1000039297

Research Interests

6

Research Areas

3

Research History

5

1976 - 1991

Faculty of Pharmaceutical Sciences, The University of Tokushima
1991

Faculty of Pharmaceutical Sciences, The University of Tokushima
1981 - 1982

米国ハーネマン医科大学準教授(併任)
1975 - 1976

Faculty of Pharmaceutical Sciences, The University of Tokushima
1973 - 1975

Faculty of Pharmaceutical Sciences, The University of Tokushima

Education

4

- 1973

Osaka University
- 1973

Graduate School, Division of Natural Science, Osaka University
- 1967

Department of Biology, Faculty of Science, Okayama University
- 1967

Faculty of Science, Okayama University

Committee Memberships

4

Awards

2

1987

康楽賞
1983

日本生化学会奨励賞

Misc.

34

Benzoylphloroglucinol derivatives from Hypericum scabrum

M Matsuhisa, Y Shikishima, Y Takaishi, G Honda, M Ito, Y Takeda, H Shibata, T Higuti, OK Kodzhimatov, O Ashurmetov

JOURNAL OF NATURAL PRODUCTS, 65(3) 290-294, Mar, 2002
Dramatic Induction by Flavone and its derivatives of Susceptibility to β-Lactam Antibiotics in Methicillin-resistant Staphylococcus aureus.

Polyphenols Communications, 127-128, 2002
Coumarins and γ-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release.

Phytochemistry, 59, 649-654, 2002
Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus

K Kawazoe, A Yutani, K Tamemoto, S Yuasa, H Shibata, T Higuti, Y Takaishi

JOURNAL OF NATURAL PRODUCTS, 64(5) 588-591, May, 2001
Alkane derivative-bacteriorhodopsin interaction : proton transport and protein structure(共著)

Colloids and Surfaces B : Biointerfaces, 22(1) 31-38, 2001
Photocurrent of purple membrane adsorbed onto a thin polymer film: Effects of monovalent and divalent ions

A. Shibata, K. Yamada, H. Ikema, S. Ueno, E. Muneyuki, T. Higuti

Studies in Surface Science and Catalysis, 132(132) 635-638, 2001
Stoichiometry of subunit a in rat liver mitochondrial H+-ATP synthase and membrane topology of its putative Ca2+-dependent regulatory region.

Biochim.Biophys.Acta, 1504(2/3) 220-228, 2001
Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus.(共著)

J.Ethnopharmacol., (72) 483-488, 2000
Synchronized transcriptional gene expression of H+-ATP synthase subunits in different tissues of Fischer 344 rets of different ages.(共著)

Eur.J.Biochem., 267(23) 6938-6942, 2000
A xanthanolide with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. (共著)

J. Pharm. Pharmacol., 49,1042-1044, 1997
Extraction and purification of effective antimicrobial constituents of Terminalia chebula Retz. against methicillin-resistant Staphylococcus aureus. (共著)

Youichi SATO, Hideki OKETANI, Kenichi SINGYOUCHI, Tetsuya OHTSUBO, Masaru KIHARA, Hirofumi SHIBATA, Tomihiko HIGUTI

Biol. Pharm. Bull., 20(4) 401-404, 1997
Gene expression of subunit c(P1), subunit c(P2), and oligomycin sensitivity conferring protein may play a key role in biogenesis of H⁺-ATP synthase in various rat tissues. (共著)

J. Biol. Chem., 272(9) 6034-6037, 1997
Isolation and Characterization of a-Type HC3 and b-Type HC5 Subunit Genes of Human Proteasomes : Distinct Gene Organizations and Pro-moter Functions.

J. Mol. Biol., 244,117-124, 1995
The Functional Expression of a Rat cDNA Encoding OSCP in The Yeast Saccharomyces cerevisiae

Biochem. Biophys. Res. Commun., 207,943-949, 1995
Specific Delay of Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid Lipofuscinosis (Batten Disease)

Junji Ezaki, Leonhard S. Wolfe, Tomihiko Higuti, Kazumi Ishidoh, Eiki Kominami

Journal of Neurochemistry, 64(2) 733-741, 1995
The Functional Expression of a Rat cDNA Encoding OSCP in The Yeast ┣DBSaccharomyces cerevisida(/)-┫DB

┣DBBiochem. Biophys. Res. Commun(/)-┫DB., 244 117-124, 1995
Specific Delay of Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid-Lipofuscinosis(Batten Disease).

┣DBJ. Neurochemistrry(/)-┫DB, 207 943-949, 1995
生体超分子システムと生命「生体超分子システム--生命理解のかなめ--」

1993
エネルギー変換システム「生体超分子システム--生命理解のかなめ--」

蛋白質・核酸・酵素, 38,1117-1132, 1993
The Complete Amino Acid Sequence of Subunit d of Rat Liver Mitochondrial H⁺-ATP Synthase

J. Biochem., 114,714-717, 1993

More

Books and Other Publications

8

分子細胞生物学基礎実験法改定第2版(共著)

株式会社南江堂, 2001
新ミトコンドリア学(共著)

共立出版株式会社, 2001
切って集めたタンパク質.「分子がつくるナノの不思議」(第14回「大学と科学」公開シンポジウム組織委員会編)

株式会社クバプロ, 2000
生体超分子システム

共立出版, 1995
「分子細胞生物学基礎実験法」,南江堂

1994
Experimental Manual for Molecular Cell Biology

1994
Isolation and Characterization of a-Type HC3 and b-Type HC5 Subunit Genes of Human Proteasomes : Distinct Gene Organizations and Promoter Functions.

┣DBJ. Mol. Biol(/)-┫DB., 1994
Function of Mitochondrial H⁺-Pumps as a Molecular Parallel Condenser. In : New Functionality Materials, Volume B : Synthesis and Function Control of Biofunctionality Materials

Elsevier Science Publishers B. V. (Amsterdam), 1993

Professional Memberships

7

Works

5

Research Projects

7

生薬からのMRSA抗菌薬の開発

保健医療分野における基礎研究推進事業, 1992
ミトコンドリアの形態形成の分子機作

大型放射光施設利用研究推進, 1990
ミトコンドリアATP合成酵素の活性制御の分子機作

大型放射光施設利用研究推進, 1978
生薬からのMRSA抗菌薬の開発
Development of anti-MRSA drug from natural resource
Molecular mechanism of mitochondrial biogenesis
Regulatory mechanism of mitochondrial ATP synthase

Industrial Property Rights

11