FUTAKI Shiroh

J-GLOBAL         Last updated: Oct 16, 2019 at 13:17
 
Avatar
Name
FUTAKI Shiroh
Affiliation
Kyoto University
Section
Institute for Chemical Research, Division of Biochemistry, Biofunctional Design Chemistry
Degree
Doctor of Pharmaceutical Science

Research Areas

 
 

Published Papers

 
Shota Ichimizu, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Komei Ikegami, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida, Takahiro Seki, Hiroshi Katsuki, Shiroh Futaki, Masaki Otagiri, Toru Maruyama
Journal of Controlled Release   304 156-163   Jun 2019   [Refereed]
© 2019 Elsevier B.V. We recently developed a cell-penetrating drug carrier composed of albumin (HSA)combined with palmitoyl-cyclic-(D-Arg) 12 . While it is possible that the palmitoyl-cyclic-(D-Arg) 12 /HSA enters the cell mainly via macropinocyt...
Sakai T, Kawano K, Iino M, Takeuchi T, Imanishi M, Futaki S
Chembiochem : a European journal of chemical biology   20(16) 2151-2159   Aug 2019   [Refereed]
Akiko Okuda, Shinya Tahara, Hisaaki Hirose, Toshihide Takeuchi, Ikuhiko Nakase, Atsushi Ono, Masanori Takehashi, Seigo Tanaka, Shiroh Futaki
Biomacromolecules   20(5) 1849-1859   May 2019   [Refereed]
© Copyright 2019 American Chemical Society. To facilitate the cytosolic delivery of larger molecules such as proteins, we developed a new cell-penetrating peptide sequence, named Pas2r12, consisting of a repeated Pas sequence (FFLIG-FFLIG) and d-d...
Futaki S, Matsuzaki K, Goto Y
Chembiochem : a European journal of chemical biology   20(16) 2015-2016   Aug 2019   [Refereed]
Yoshimasa Kawaguchi, Shoko Ise, Yusuke Azuma, Toshihide Takeuchi, Kenichi Kawano, Toan Khanh Le, Junko Ohkanda, Shiroh Futaki
Bioconjugate Chemistry   30(2) 454-460   Feb 2019   [Refereed]
© 2018 American Chemical Society. Marked promotion of membrane permeation of a cell-penetrating peptide, octaarginine (R8), was attained by attachment to a single 2,2′-dipicolylamine moiety (DPA-R8) that forms 1:1 complexes with metal ions. Studie...
Kawano K, Ogushi M, Masuda T, Futaki S
Chemical & pharmaceutical bulletin      Jul 2019   [Refereed]
Tsuji S, Shinoda K, Futaki S, Imanishi M
The Analyst   143(16) 3793-3797   Aug 2018   [Refereed]
Akishiba M, Futaki S
Molecular pharmaceutics   16(6) 2540-2548   Jun 2019   [Refereed]
Azuma Y, Imai H, Kawaguchi Y, Nakase I, Kimura H, Futaki S
Angewandte Chemie (International ed. in English)   57(39) 12771-12774   Aug 2018   [Refereed]
Masuda T, Baba K, Nomura T, Tsujita K, Murayama T, Itoh T, Takatani-Nakase T, Sokabe M, Inagaki N, Futaki S
Communications biology   2 243   2019   [Refereed]
Arginine-rich cell-penetrating peptide-modified exosomes for macropinocytosis induction and effective cellular uptake
Noguchi Kosuke, Aoki Ayako, Kobayashi Nahoko Bailey, Takatani-Nakase Tomoka, Yoshida Tetsuhiko, Fujii Ikuo, Futaki Shiroh, Nakase Ikuhiko
JOURNAL OF PEPTIDE SCIENCE   24 S58   Sep 2018   [Refereed]
Sakagami Koki, Masuda Toshihiro, Kawano Kenichi, Futaki Shiroh
MOLECULAR PHARMACEUTICS   15(3) 1332-1340   Mar 2018   [Refereed]
Shota Ichimizu, Hiroshi Watanabe, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Yuka Nakamura, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Ryota Tanaka, Yuki Enoki, Yu Ishima, Akihiko Kuniyasu, Yoshihiro Kobashigawa, Hiroshi Morioka, Shiro Futaki, Masaki Otagiri, Toru Maruyama, Toru Maruyama
Journal of Controlled Release   277 23-34   May 2018
© 2018 Human serum albumin (HSA) is a superior carrier for delivering extracellular drugs. However, the development of a cell-penetrating HSA remains a great challenge due to its low membrane permeability. We report herein on the design of a serie...
Kouki Shinoda, Shogo Tsuji, Shiroh Futaki, Miki Imanishi
ChemBioChem   19(2) 171-176   Jan 2018   [Refereed]
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim RNA-binding proteins recognizing unique sequences within large transcriptomes serve as a powerful tool to control RNA metabolism. Pumilio and fem-3 mRNA-binding factor (PUF) proteins are consider...
Ryo Hirata, Ayame Torii, Kenichi Kawano, Shiroh Futaki, Ayumi Imayoshi, Kazunori Tsubaki
Tetrahedron   74(27) 3608-3615   Jul 2018   [Refereed]
© 2018 Elsevier Ltd Fluorescent dyes possessing a variety of arylacetylenes at the 9-position of a xanthene skeleton were synthesized and their optical properties were investigated. The π system effectively expanded over the xanthene skeleton and ...
Shiroh Futaki, Ikuhiko Nakase
Accounts of Chemical Research   50(10) 2449-2456   Oct 2017   [Refereed]
© 2017 American Chemical Society. ConspectusOne of the recent hot topics in peptide-related chemical biology research is the potential of cell-penetrating peptides (CPPs). Owing to their ability to deliver exogenous molecules into cells easily and...
Akari Yamagami, Kenichi Kawano, Shiroh Futaki, Kouji Kuramochi, Kouji Kuramochi, Kazunori Tsubaki
Tetrahedron   73(50) 7061-7066   Dec 2017   [Refereed]
© 2017 Elsevier Ltd New V-shaped xanthene dyes 3–6 containing piperidino groups at the resonance sites on their skeletons were constructed as second-generation V-shaped dyes and their functions were investigated. The non-symmetric compound 5 had h...
Gen Tanaka, Yoshimasa Kawaguchi, Keiko Kuwata, Toshihide Takeuchi, Ikuhiko Nakase, Shiroh Futaki
Photoaffinity Labeling for Structural Probing Within Protein   225-240   Sep 2017
© Springer Japan KK 2017. Peptides with membrane permeability have been used extensively as carriers for intracellular delivery of bioactive molecules, and endocytosis plays an important role in the cellular uptake of these peptides. Elucidating t...
Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao Hsin Yu, Ikuhiko Nakase, Tomoka Takatani-Nakase, Fatemeh Madani, Astrid Gräslund, Shiroh Futaki
Nature Chemistry   9 751-761   Aug 2017
© 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. One of the major obstacles in intracellular targeting using antibodies is their limited release from endosomes into the cytosol. Here we report an approach to deliv...
Murayama T, Masuda T, Afonin S, Kawano K, Takatani-Nakase T, Ida H, Takahashi Y, Fukuma T, Ulrich AS, Futaki S
Angewandte Chemie (International ed. in English)   56(26) 7644-7647   Jun 2017   [Refereed]
Backlund Coralie M., Sgolastra Federica, Otter Ronja, Minter Lisa M., Takeuchi Toshihide, Futaki Shiroh, Tew Gregory N.
POLYMER CHEMISTRY   8(43) 6688   Nov 2017   [Refereed]
Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Gräslund A, Futaki S
Nature chemistry   9(8) 751-761   Aug 2017   [Refereed]
© 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. One of the major obstacles in intracellular targeting using antibodies is their limited release from endosomes into the cytosol. Here we report an approach to deliv...
Nakase I, Noguchi K, Aoki A, Takatani-Nakase T, Fujii I, Futaki S
Scientific reports   7(1) 1991   May 2017   [Refereed]
[Membrane translocation of arginine-rich cell-penetrating peptides].
Futaki S
Seikagaku. The Journal of Japanese Biochemical Society   89(1) 8-14   Feb 2017   [Refereed]
Miki Imanishi, Shogo Tsuji, Akiyo Suda, Shiroh Futaki
Chemical Communications   53 12930-12933   Jan 2017
© 2017 The Royal Society of Chemistry. We found that Escherichia coli MazF toxin, an ACA-sequence-specific endoribonuclease, was sensitive to N 6 -methyladenosine (m6A), representing the first m6A-sensitive RNA cleavage enzyme. The methyl-sensitiv...
I. Nakase, N. Ueno, N. Ueno, M. Katayama, M. Katayama, K. Noguchi, K. Noguchi, T. Takatani-Nakase, N. B. Kobayashi, N. B. Kobayashi, T. Yoshida, T. Yoshida, I. Fujii, S. Futaki
Chemical Communications   53 317-320   Jan 2017
© The Royal Society of Chemistry. We demonstrate a novel system for inducing clustering of cell surface receptors via recognition peptide segments displayed on exosomes, leading to receptor activation. With this system, targeting of receptor-expre...
Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN
Polymer chemistry   7(48) 7514-7521   Dec 2016   [Refereed]
© 2016 The Royal Society of Chemistry. The plasma membrane is a major obstacle in the development and use of biomacromolecules for intracellular therapeutic applications. Protein transduction domains (PTDs) have been used to overcome this barrier,...
Oku A, Imanishi M, Noshiro D, Murayama T, Takeuchi T, Nakase I, Futaki S
Biopolymers   108(1)    Jan 2017   [Refereed]
Shiroh Futaki
Seikagaku   89 8-14   Jan 2017
Tsuji S, Futaki S, Imanishi M
Chemical communications (Cambridge, England)   52(99) 14241-14241   Dec 2016   [Refereed]
© The Royal Society of Chemistry. A 5mC-selective TALE-repeat was created by screening a TALE repeat library containing randomized amino acids at repeat variable diresidues and their neighboring residues. The new repeat showed high 5mC discriminat...
Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H
Biological & pharmaceutical bulletin   39(11) 1829-1829   Nov 2016   [Refereed]
Miyajima R, Tsuda Y, Inokuma T, Shigenaga A, Imanishi M, Futaki S, Otaka A
Biopolymers   106(4) 531-546   Nov 2016   [Refereed]
Nakase I, Noguchi K, Fujii I, Futaki S
Scientific reports   6    Oct 2016   [Refereed]
Backlund CM, Takeuchi T, Futaki S, Tew GN
Biochimica et biophysica acta   1858(7,Pt.A) 1450-1450   Jul 2016   [Refereed]
Kawaguchi Y, Takeuchi T, Kuwata K, Chiba J, Hatanaka Y, Nakase I, Futaki S
Bioconjugate chemistry   27(4) 1130-1130   Apr 2016   [Refereed]
Takeuchi T, Futaki S
Chemical & pharmaceutical bulletin   64(10) 1437-1437   Oct 2016   [Refereed]
Shogo Tsuji, Shiroh Futaki, Miki Imanishi
Chemical Communications   52 14238-14241   Jan 2016
© The Royal Society of Chemistry. A 5mC-selective TALE-repeat was created by screening a TALE repeat library containing randomized amino acids at repeat variable diresidues and their neighboring residues. The new repeat showed high 5mC discriminat...
Yoshihiro Kuroda, Nahoko Kato-Kogoe, Emi Tasaki, Mayumi Yuasa-Sunagawa, Koji Yamanegi, Keiji Nakasyo, Ikuhiko Nakase, Shiroh Futaki, Yumi Tohyama, Munetaka Hirose
European Journal of Pharmacology   767 220   Nov 2015
Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M
European journal of pharmacology   765 24-33   Oct 2015   [Refereed]
I. Nakase; Y. Kawaguchi; M. Nomizu; S. Futaki
Trends in Glycoscience and Glycotechnology   27(155) 81-88   May 2015   [Refereed][Invited]
T. Takeuchi; M. Suzuki; N. Fujikake; H. A. Popiel; H. Kikuchi; S. Futaki; K. Wada; Y. Nagai
Proceedings of the National Academy of Sciences of the United States of America   112(19) E2497-E2506   May 2015   [Refereed]
Determining the relationship between structure, internalization, and delivery efficiency for protein mimics
Backlund Coralie, Takeuchi Toshihide, Futaki Shiroh, Tew Gregory
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   250    Aug 2015   [Refereed]
T. Takeuchi; H. A. Popiel; S. Futaki; K. Wada; Y. Nagai
Current Medicinal Chemistry   21(23) 2575-2582   Aug 2014   [Refereed]
I. Nakase; K. Osaki; G. Tanaka; A. Utani; S. Futaki
Biochemical and Biophysical Research Communications   446(4) 857-862   Apr 2014   [Refereed]
Y. Azuma; T. Kükenshöner; G. Ma; J.-I. Yasunaga; M. Imanishi; G. Tanaka; I. Nakase; T. Maruno; Y. Kobayashi; K. M. Arndt; M. Matsuoka; S. Futaki
Chemical Communications   50(48) 6364-6367   Jun 2014   [Refereed]
Nakase I, Takeuchi T, Futaki S
Methods in molecular biology (Clifton, N.J.)   1324 387-396   2015   [Refereed]
Kenji Mishiro, Takumi Furuta, Takahiro Sasamori, Kazuhiro Hayashi, Norihiro Tokitoh, Shiroh Futaki, Takeo Kawabata
Journal of the American Chemical Society   135 17236   Nov 2013
S. Katayama; I. Nakase; Y. Yano; T. Murayama; Y. Nakata; K. Matsuzaki; S. Futaki
Biochimica et Biophysica Acta - Biomembranes   1828(9) 2134-2142   Sep 2013   [Refereed]
Y. Kuroda; N. Kato-Kogoe; E. Tasaki; E. Murata; K. Ueda; M. Abe; K. Miyamoto; I. Nakase; S. Futaki; Y. Tohyama; M. Hirose
European Journal of Pharmacology   698(1-3) 87-94   Jan 2013   [Refereed]
S. Sasaki; S. Futaki
Yakugaku Zasshi   134(4) 499-500   Apr 2014   [Refereed]
F. Madani; R. Abdo; S. Lindberg; H. Hirose; S. Futaki; Ü. Langel; A. Gräslund
Biochimica et Biophysica Acta - Biomembranes   1828(4) 1198-1204   Apr 2013   [Refereed]
D. Noshiro; K. Sonomura; H.-H. Yu; M. Imanishi; K. Asami; S. Futaki
Bioconjugate Chemistry   24(2) 188-195   Feb 2013   [Refereed]
I. Nakase; G. Tanaka; S. Futaki
Molecular BioSystems   9(5) 855-861   May 2013   [Refereed]
C.M. Yamazaki; I. Nakase; H. Endo; S. Kishimoto; Y. Mashiyama; R. Masuda; S. Futaki; T. Koide
Angewandte Chemie - International Edition   52(21) 5497-5500   May 2013   [Refereed]
S. Futaki; H. Hirose; I. Nakase
Current Pharmaceutical Design   19(16) 2863-2868   May 2013   [Refereed]
Y. Kawaguchi; G. Tanaka; I. Nakase; M. Imanishi; J. Chiba; Y. Hatanaka; S. Futaki
Bioorganic and Medicinal Chemistry Letters   23(13) 3738-3740   Jul 2013   [Refereed]
C. Gehin; J. Montenegro; E.-K. Bang; A. Cajaraville; S. Takayama; H. Hirose; S. Futaki; S. Matile; H. Riezman
Journal of the American Chemical Society   135(25) 9295-9298   Jun 2013   [Refereed]
K. Mishiro; T. Furuta; T. Sasamori; K. Hayashi; N. Tokitoh; S. Futaki; T. Kawabata
Journal of the American Chemical Society   135(37) 13644-13647   Sep 2013   [Refereed]
S. Pujals; H. Miyamae; S. Afonin; T. Murayama; H. Hirose; I. Nakase; K. Taniuchi; M. Umeda; K. Sakamoto; A.S. Ulrich; S. Futaki
ACS Chemical Biology   8(9) 1894-1899   Sep 2013   [Refereed]
S. Tsuji; S. Futaki; M. Imanishi
Biochemical and Biophysical Research Communications   441(1) 262-265   Nov 2013   [Refereed]
S. Futaki; D. Noshiro; T. Kiwada; K. Asami
Accounts of Chemical Research   46(12) 2924-2933   Dec 2013   [Refereed]
Y. Shimatani; M. Ito; T. Ohgita; A. Yamada; S. Hama; A. Gräslund; S. Lindberg; Ü. Langel; H. Harashima; I. Nakase; S. Futaki; K. Kogure
Biopolymers   100(6) 698-704   Nov 2013   [Refereed]
D. Noshiro; K. Asami; S. Futaki
Bioorganic and Medicinal Chemistry   20(23) 6870-6876   Dec 2012   [Refereed]
G. Tanaka; I. Nakase; Y. Fukuda; R. Masuda; S. Oishi; K. Shimura; Y. Kawaguchi; T. Takatani-Nakase; Ü. Langel; A. Gräslund; K. Okawa; M. Matsuoka; N. Fujii; Y. Hatanaka; S. Futaki
Chemistry and Biology   19(11) 1437-1446   Nov 2012   [Refereed]
I. Nakase; H. Akita; K. Kogure; A. Gräslund; U. Langel; H. Harashima; S. Futaki
Accounts of Chemical Research   45(7) 1132-1139   Jul 2012   [Refereed]
K. Sakamoto; K. Aburai; T. Morishita; K. Sakai; H. Sakai; M. Abe; I. Nakase; S. Futaki
Chemistry Letters   41(10) 1078-1080   Oct 2012   [Refereed]
H. Hirose; T. Takeuchi; H. Osakada; S. Pujals; S. Katayama; I. Nakase; S. Kobayashi; T. Haraguchi; S. Futaki
Molecular Therapy   20(5) 984-993   May 2012   [Refereed]
K. Takayama; H. Hirose; G. Tanaka; S. Pujals; S. Katayama; I. Nakase; S. Futaki
Molecular Pharmaceutics   9(5) 1222-1230   May 2012   [Refereed]
I. Nakase; Y. Konishi; M. Ueda; H. Saji; S. Futaki
Journal of Controlled Release   159(2) 181-188   Apr 2012   [Refereed]
H. Kono; M. Imanishi; S. Negi; K. Tatsutani; Y. Sakaeda; A. Hashimoto; C. Nakayama; S. Futaki; Y. Sugiura
FEBS Letters   586(6) 918-923   Mar 2012   [Refereed]
M. Imanishi; K. Matsumura; S. Tsuji; T. Nakaya; S. Negi; S. Futaki; Y. Sugiura
Biochemistry   51(16) 3342-3348   Apr 2012   [Refereed]
T. Ochiai; M. Nagata; K. Shimoyama; T. Kato; T. Asaoka; M. Kondo; T. Dewa; K. Yamashita; A. Kashiwada; S. Futaki; H. Hashimoto; M. Nango
ACS Macro Letters   1(1) 28-32   Jan 2012   [Refereed]
S. Kawamoto; T. Miyakawa; M. Takasu; R. Morikawa; T. Oda; H. Saito; S. Futaki; H. Nagao
International Journal of Quantum Chemistry   112(1) 178-183   Jan 2012   [Refereed]
Y. Azuma; H. Imai; T. Yoshimura; T. Kawabata; M. Imanishi; S. Futaki
Organic and Biomolecular Chemistry   10(30) 6062-6068   Aug 2012   [Refereed]
I. Nakase; S. Okumura; S. Katayama; H. Hirose; S. Pujals; H. Yamaguchi; S. Arakawa; S. Shimizu; S. Futaki
Chemical Communications   48(90) 11097-11099   Nov 2012   [Refereed]
S. Kawamoto; M. Takasu; T. Miyakawa; R. Morikawa; T. Oda; S. Futaki; H. Nagao
Molecular Simulation   38(5) 366-368   2012   [Refereed]
Y. Ueda; F.-Y. Wei; T.-I. Hide; H. Michiue; K. Takayama; T. Kaitsuka; H. Nakamura; K. Makino; J.-I. Kuratsu; S. Futaki; K. Tomizawa
Biomaterials   33(35) 9061-9069   Dec 2012   [Refereed]
M. Imanishi; K. Yamamoto; H. Yamada; Y. Hirose; H. Okamura; S. Futaki
ACS Chemical Biology   7(11) 1817-1821   Nov 2012   [Refereed]
I. Nakase; S. Okumura; G. Tanaka; K. Osaki; M. Imanishi; S. Futaki
Angewandte Chemie - International Edition   51(30) 7464-7467   Jul 2012   [Refereed]
S.M. Shaheen; H. Akita; T. Nakamura; S. Takayama; S. Futaki; A. Yamashita; R. Katoono; N. Yui; H. Harashima
Biomaterials   32(26) 6342-6350   Sep 2011   [Refereed]
C.Y. Looi; M. Imanishi; S. Takaki; M. Sato; N. Chiba; Y. Sasahara; S. Futaki; S. Tsuchiya; S. Kumaki
PLoS ONE   6(8) e23640   Aug 2011   [Refereed]
Y. Sakurai; H. Hatakeyama; Y. Sato; H. Akita; K. Takayama; S. Kobayashi; S. Futaki; H. Harashima
Biomaterials   32(24) 5733-5742   Aug 2011   [Refereed]
S. Negi; M. Imanishi; M. Sasaki; K. Tatsutani; S. Futaki; Y. Sugiura
Biochemistry   50(28) 6266-6272   Jul 2011   [Refereed]
K. Sonomura; H. Kuyama; E.-I. Matsuo; S. Tsunasawa; S. Futaki; O. Nishimura
Analytical Biochemistry   410(2) 214-223   Mar 2011   [Refereed]
S. Kawamoto; M. Takasu; T. Miyakawa; R. Morikawa; T. Oda; S. Futaki; H. Nagao
Journal of Chemical Physics   134(9) 95103   Mar 2011   [Refereed]
S. Katayama; H. Hirose; K. Takayama; I. Nakase; S. Futaki
Journal of Controlled Release   149(1) 29-35   Jan 2011   [Refereed]
M. Imanishi; A. Nakamura; M. Doi; S. Futaki; H. Okamura
Angewandte Chemie - International Edition   50(40) 9396-9399   Sep 2011   [Refereed]
The formation of particle-like structure on cell membranes accompanies direct influx of arginine-rich peptides into cells
Hirose, H.; Takeuchi, T.; Nakase, I.; Futaki, S.
BIOPOLYMERS   96(4) 498-498   2011   [Refereed]
Hiraga Takashi, Ueno Ichiro, Shiga Noriyasu, Watanabe Hirofumi, Futaki Shiroh, Kubo Masaki, Takarada Shigeru, Tanaka Norio
ORGANIC PHOTONIC MATERIALS AND DEVICES XIII   7935    2011   [Refereed]
A. Gräslund; F. Madani; S. Lindberg; U. Langel; S. Futaki
Journal of Biophysics   2011 414729   2011   [Refereed]
H. Akita; K. Kogure; R. Moriguchi; Y. Nakamura; T. Higashi; T. Nakamura; S. Serada; M. Fujimoto; T. Naka; S. Futaki; H. Harashima
Journal of Controlled Release   149(1) 58-64   Jan 2011   [Refereed]
H.-H. Yu; I. Nakase; S. Pujals; H. Hirose; G. Tanaka; S. Katayama; M. Imanishi; S. Futaki
Biochimica et Biophysica Acta - Biomembranes   1798(12) 2249-2257   Dec 2010   [Refereed]
I. Nakase; K. Kogure; H. Harashima; S. Futaki
Methods in molecular biology (Clifton, N.J.)   683 525-533   2011   [Refereed]
R. Miyamoto; H. Akizawa; T. Nishikawa; T. Uehara; Y. Azuma; I. Nakase; S. Futaki; H. Hanaoka; Y. Iida; K. Endo; Y. Arano
Bioconjugate Chemistry   21(11) 2031-2037   Nov 2010   [Refereed]
Nakase Ikuhiko, Kobayashi Sachiko, Futaki Shiroh
DRUG DISCOVERY TODAY   15(23-24) 1095   Dec 2010   [Refereed]
M. Imanishi; C. Imamura; C. Higashi; W. Yan; S. Negi; S. Futaki; Y. Sugiura
Biochemical and Biophysical Research Communications   400(4) 625-630   Oct 2010   [Refereed]
CHEMICAL AND BIOLOGICAL FACTORS THAT CONTRIBUTE TO THE INTERNALIZATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES
Futaki Shiroh
JOURNAL OF GENE MEDICINE   12(12) 1015   Dec 2010   [Refereed]
K. Shimane; E.N. Kodama; I. Nakase; S. Futaki; Y. Sakurai; Y. Sakagami; X. Li; T. Hattori; S.G. Sarafianos; M. Matsuoka
International Journal of Biochemistry and Cell Biology   42(9) 1482-1488   Sep 2010   [Refereed]

Misc

 
R. Kawano, D. Noshiro, T. Osaki, T. Osaki, K. Kamiya, K. Asami, S. Futaki, S. Takeuchi, S. Takeuchi
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013   1 32-34   Jan 2013
This paper describes the electrical detection of single-stranded DNA (ssDNA) at the single molecule level using an engineered alamethicin (Aim) channel embedded in bilayer lipid membranes (BLMs). Nanopore sequencing has the potential to become a d...
Creation of Artificial Epidermal Growth Factor Receptor Activated by Bivalent Leucine-zipper Ligand
Tanaka, G. ,Nakase, I.; Okumura, S.; Osaki, K.; Futaki, S.
第2回統合物質国際シンポジウム(2012) ,名古屋(名古屋大学)      Dec 2012   [Refereed]
5'-Tthymine recognition by TAL effectors.
TSUJI, S. ,Imanishi, M.; Futaki, S.
The 39th Inernational Symposium on Nucleic Acids Chemistry ,Toyoda Auditorium, Nagoya University      Nov 2012   [Refereed]
Resetting the Cellular Circadian Clock by an Artificial Zinc-finger Transcription Factor
Imanishi, M. ,Nakamura, A.; Doi, M.; Futaki, S.; Okamura, H.
FASEB SCIENCE RESEARCH CONFERENCES Genome Engineering: Research & Applications" ,Lucca, Italy      Sep 2012   [Refereed]
Resetting of the cellular circadian clock by an artificial zinc-finger transcription factor
Imanishi, M. ,Nakamura, A.; Doi, M.; Okamura, H.; Futaki, S.
金属の関与する生体関連反応シンポジウム(SRM2012) ,金沢(金沢大学)      May 2012   [Refereed]
Design and Creation of a Ca2+-sensitive Artificial Channel Protein
NOSHIRO, Daisuke. ,SONOMURA, Kazuhiro,; Yu H.H,; IMANISHI, Miki,; ASAMI, Kouji,; FUTAKI, Shiroh.
International Symposium on Innovative Nanobiodevices ISIN 2012 ,Nagoya, Japan      Mar 2012   [Refereed]
A photocross-link approach to identify receptors that stimulate internalization of oligoarginine peptides
FUTAKI, Shiroh. ,TANAKA, Gen.; NAKASE, Ikuhiko.; FUKUDA, Yasunori.; MASUDA, Ryo.; OISHI, Shinya.; FUJII, Nobutaka.; HATANAKA, Yasumaru.
8th AFMC International Medicinal Chemistry Symposium “Frontier of Medicinal Science” ,Keio Plaza Hotel Tokyo      Dec 2011   [Refereed]
Circadian Rhythmic Gene Expression Induced by Artificial Clock Proteins
YAMAMOTO, Kazatoshi ,IMANISHI, Miki.; HIROSE, Yuka.; OKAMURA, Hitoshi.; FUTAKI、Shiroh.
The 38th International Symposium on Nucleic Acid Chemistry ,Clark Memorial Student Center, Hokkaido University      Nov 2011   [Refereed]
ELUCIDATING THE EFFECT OF EPSIN DERIVED AMPHIPATHIC PEPTIDE ON CELL-MEMBRANE ARCHITECTURE
PUJALS Silvia;TANIUCHI Kentaroh;MIYAMAE Hiroki;UMEDA Masato;FUTAKI Shiroh
ペプチド討論会講演要旨集   48th 80   Sep 2011   [Refereed]
IN VIVO TUMOR ACCUMULATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES AND ANTICANCER DRUG DELIVERY
NAKASE Ikuhiko;KONISHI Yusuke;UEDA Masashi;SAJI Hideo;FUTAKI Shiroh
ペプチド討論会講演要旨集   48th 30   Sep 2011   [Refereed]
Creation of Metal Sensitive Artificial Ion Channels
NOSHIRO, Daisuke. ,ASAMI, Kouji.; FUTAKI, Shiroh.
22nd American Peptide Symposium ,San Diego, CA, USA      Jun 2011   [Refereed]
A. Nishio; N. Sawa; K. Onodera; S. Sakamoto; Y. Araki; I. Nakase; S. Futaki; Y. Inoue; T. Wada
Nucleic acids symposium series (2004)   (53) 55-56   Dec 2009
In this study, a series of novel alpha-Peptide ribonucleic acid (alpha-PRNA) oligomers, possessing alternative alpha-PRNA/arginine or serine sequences, were newly designed, synthesized, and evaluated as the third-generation PRNA. As expected, thes...
Bidirectional control of the helical structure of a Dpa-containing peptide using divalent metal ions
AZUMA, Yusuke. ,IMAI, Haruka.; IMANISHI, Miki.; YOSHIMURA, Tomoyuki.; KABABATA, Takeo.; FUTAKI, Shiroh.
22nd American Peptide Symposium ,Sheraton Hotel or Marina, San Diego, California      Jun 2011   [Refereed]
Dynamics of membrane-associated molecules that accompany direct penetration of arginine-rich peptides into cells
Hisaaki HIROSE ,Toshihide TAKEUCHI, Ikuhiko NAKASE, Shiroh FUTAKI
The 27th Naito Conference (Membrane Dynamics and Lipid Biology [I]) ,Ch?terais? Gateaux Kingdom SAPPORO      Jun 2010   [Refereed]
Design and Creation of the GCN4-bZIP Proteins Functionalized with Iminodiacetic Acid for On/Off Switch of the DNA Binding by Metal Ions
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S
Gordon Research Conference on Bioorganic Chemistry ,Proctor Academy (Andover, NH)      Jun 2010   [Refereed]
Functionalization of GCN4-bZIP with iminodiacetic acid that allow the DNA binding to be controlled by a metal ion
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S
京大/阪大/ソウル大合同シンポジウム ,吹田(大阪大学)      May 2010   [Refereed]
T. Wada; N. Sawa; H. Sato; S. Futaki; Y. Inoue
Nucleic acids symposium series (2004)   (52) 673-674   Dec 2008
A novel nucleic acid model using alpha-peptide ribonucleic acid (alpha-PRNA) possessing alternative alpha-PRNA/arginine sequences, where the arginine residue would be expected to stabilize the complex not only by the conventional hydrogen-bonding ...
Promoted cellular uptake of arginine-rich peptides bearing penetration accelerating sequences (Pas)
Takayama K ,Nakase Ikuhiko, Michiue Hiroyuki, Takeuchi Toshihide, Tomizawa Kazuhito, Matsui Hideki, Futaki Shiroh
3rd Asia-Pacific International Peptide Symposium ,Jeju, Korea      Nov 2009   [Refereed]
Co(II)-responsive DNA binding switch of the designed GCN4-bZIP protein bearing cysteine moieties functionalized with iminodiacetic acids (Ida)
Azuma Y ,Imanisi M, Yoshimura T, Kawabata T, Futaki, S
2nd Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS09) ,Tokyo      Nov 2009   [Refereed]
Stabilization of the Channel Peptide Assembly: Metal Coordination with an Additional Histidine Yielded Extremely Stable Channels
Noshiro D ,Asami K, Futaki S
2nd Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS09) ,東京      Sep 2009   [Refereed]
Design and creation of a metal-responsive GCN4-bZIP protein modified with iminodiacetic acid (Ida)
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S
2nd International Symposium on Bioinorganic Chemimstry of the New Era ,Takayama      Aug 2009   [Refereed]
Metal-induced DNA-binding switch of bZIP proteins modified with iminodiacetic acid (Ida)
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S
The Fifth iCeMS International Symposium, Biomaterials at the interface of chemistry, physics, and biology ,Kyoto      Jul 2009   [Refereed]
Facile One-Pot Modification with Oligoarginine for Intracellular Delivery
Takayama K ,Tadokoro A, Nakase I, Futaki S
第45回 ペプチド討論会The 46th Japanese Peptide Symposium ,東京      Oct 2008   [Refereed]
T. Wada; Y. Maeda; N. Sawa; H. Sato; S. Futaki; Y. Inoue
Nucleic acids symposium series (2004)   (50) 75-76   Dec 2006
A novel nucleic acid model using alpha-peptide ribonucleic acid (alpha-PRNA) possessing alternative alpha-PRNA/lysine and alpha-PRNA/arginine sequences, where the lysine or arginine residue are expected to stabilize the complex not only by the con...
Novel Intracellular Delivery System using pH-Dependent Fusiogenic Peptide
Nakase I ,Kobayashi S, Kawabata N, Futaki S
30th European Peptide Symposium ,Helsinki, Finland      Sep 2008   [Refereed]
Artificial Zinc Finger-Type Transcription Factors Targeting Circadian Clock Genes
Imanishi M ,Nakamura A, Futaki S
Chemistry in the New World of Bioengineering and Synthetic Biology ,Oxford, UK      Sep 2008   [Refereed]
Rapid Cellular Uptake of Octaarginine-Based Peptides Bearing Hydrophobic Amino Acid Sequences
Takayama K ,Takayama K, Takeuchi T, Nakase I, Futaki S
2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008" ,Cardiff, UK      Jun 2008   [Refereed]
Effective Macropinocytosis Induction and Membrane Penetration by FHV Peptide
Nakase I ,Hirose H, Takeuchi T, Futaki S
Cell-Penetrating Peptides (CPP) Satellite Symposium of 30th European Peptide Symposium ,Helsinki, Finland      Aug 2008   [Refereed]
Y. Hori; K. Suzuki; Y. Okuno; M. Nagaoka; S. Futaki; Y. Sugiura
Nucleic acids symposium series   (44) 295-296   Jan 2000
We have created a novel His4-type zinc finger protein (H4Sp1) engineered by Cys-- > His mutations of the Cys2His2-type zinc finger in transcription factor Sp1. The CD and NMR studies reveal that the His4 domain has Zn(II)-dependent folding propert...
An Oligoarginine-Based Cargo-Transporter System for Improving Drug Intestinal Absorption: Utilization of Self-Cleavable Peptide Linkers
Takayama K ,Hayashi Y, Suehisa Y, Fujita T, Yamamoto A,Futaki S, Kiso Y
Cell penetrating peptides: A Biochemical Society Focused Meeting ,Telford, UK      May 2007   [Refereed]
R. Tachibana; H. Harashima; S. Futaki; M. Shono; H. Kiwada
Proceedings of the Controlled Release Society   (24) 791-792   Jan 1997
Involvement of Sulfated Glycosaminoglycans with the Internalization of Basic Peptides
Suzuki T, Futaki S, Niwa M, Nakase I, Tanaka S, Ueda K, Sugiura Y
Peptide science : proceedings of the ... Japanese Peptide Symposium   2001 221-224   Mar 2002   [Refereed]

Books etc

 
Assembly Modulation of Channel-Forming Peptides
Futaki S
Self-Assembling Peptide Systems in Biology, Medicine and Engineering , , 87-104   2001   
Ligand-Induced Extramembrane Conformation Switch Controlling Alamethicin Assembly and the Channel Current
Futaki S, Asami K
Peptaibols: Fungal Peptides Containing a-Dialkyl a-Amino Acids, , 344-352   2009   
Immunoglobulin binding factor in human seminal plasma and uterine cerivical mucus
Kamada M, Maegawa M, Maeda N, Yamamoto S, Yoshikawa S, Mori H, Tanaka Y, Okada M, Shitukawa K, Irahara1 M, Aono T, Kido H, Ogushi F , Sone S, Kanayama N, Kagawa S, Ohmoto Y, Futaki S, Zhi Guo Liang, Samuel S. Koide
Current Paradigm of Reproductive Immunology, , 95-104   2009   
Chapter 37. Application of a Fusiogenic Peptide GALA for Intracellular Delivery In Cell-Penetrating Peptides: Methods and Protocols Ed. By ?lo Langel
NAKASE, Ikuhiko.; KOGURE, Kentaro.; HARASHIMA, Hideyoshi.; FUTAKI, Shiroh.
Methods in Molecular Biology, Springer Ed. By ?lo Langel, 683, 525-533   2010   

Conference Activities & Talks

 
Modulating Lipid Packing of Cell Membranes for the Access to Cell Interiors [Invited]
FUTAKI Shiroh
Chemistry and Biology of Peptides 2019   25 Jul 2019   
Redesigning Cationic Lytic Peptides to Promote the Delivery of Biomacromolecules into Cell Interiors
FUTAKI Shiroh
26th American Peptide Symposium/11th International Peptide Symposium   26 Jun 2019   
Cytosolic Delivery of Biomacromolecules [Invited]
FUTAKI Shiroh
7th Indian Peptide Society   28 Feb 2019   
Intracellular delivery of bioactive molecules using peptides [Invited]
FUTAKI Shiroh
Niigata Hybrid conference 2018   9 Feb 2019   
Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules [Invited]
FUTAKI Shiroh
10th International Peptide Symposium/55th Japanese Peptide Symposium   6 Dec 2018   
Intracellular delivery using peptides [Invited]
FUTAKI Shiroh
15 Nov 2018   
Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules [Invited]
FUTAKI Shiroh
8th Peptide Engineering Meeting (PEM8-2018)   8 Nov 2018   
Lipid packing loosening promotes the cellular entry of oligoarginine [Invited]
FUTAKI Shiroh
The Third A3 Roundtable Meeting on Chemical Probe Research Hub   31 Oct 2018   
Peptide-mediated delivery of antibodies and bioactive proteins into cells [Invited]
FUTAKI Shiroh
2018 MDO/JSSX in Kanazawa   3 Oct 2018   
Cytosolic Delivery of Biomacromolecules [Invited]
FUTAKI Shiroh
17th Akabori Conference: Japanese-German Symposium on Peptide Science   3 Sep 2018   
Peptide-mediated Delivery of Biomacromolecules into Cells [Invited]
FUTAKI Shiroh
Frontiers in Delivery of Therapeutics   3 Sep 2018   
Cytosolic Delivery of Biomacromolecules [Invited]
FUTAKI Shiroh
15th Chinese International Peptide Symposium   4 Jul 2018   
Peptide-mediated Delivery of Biomacromolecules into Cells [Invited]
FUTAKI Shiroh
22th Korean Peptide Protein Society (KPPS) Symposium   25 Jun 2018   
Cytosolic Antibody Delivery by Lipid-sensitive Endosomolytic Peptide [Invited]
FUTAKI Shiroh
IRCCS-JST CREST Joint Symposium “Chemical sciences facing difficult challenges”   24 Jan 2018   
Cytosolic delivery of biomacromolecules [Invited]
FUTAKI Shiroh
2018 International Symposium on Chemical Biology   11 Jan 2018   
Cytosolic antibody delivery by lipid-sensitive endosomelytic peptide [Invited]
FUTAKI Shiroh
The Second A3 Roundtable Meeting on Chemical Probe Research Hub   24 Nov 2017   
Peptide-mediated Delivery of Biomacromolecules into Cells [Invited]
FUTAKI Shiroh
12th Australian Peptide Conference 2017   17 Oct 2017   
Loosening of the Lipid Packing by Curvature Inducing Peptides Promotes Cell Entry of Oligoarginine
FUTAKI Shiroh
25th American Peptide Symposium   21 Jun 2017   
Redesigning Hemolytic Peptides for Cytosolic Antibody Delivery
FUTAKI Shiroh
25th American Peptide Symposium   19 Jun 2017   
Photocrosslinking approaches to identify cellular-uptake receptors of arginine-rich cell-penetrating peptides [Invited]
FUTAKI Shiroh
34th European Peptide Symposium and 8th International Peptide Symposium   9 Sep 2016   
Facilitated membrane translocation of arginine-rich peptides in the presence of curvature inducing peptides [Invited]
FUTAKI Shiroh
14th Chinese International Peptide Symposium & 5th Asia-pacific International Peptide Symposium (CPS-14 & APIPS-5)   7 Jul 2016   
Membrane-remodeling Amphypathic Helical Peptides Accelerate Direct Penetration of Octaarginine [Invited]
FUTAKI Shiroh
20th Korea Peptide Protein Society (KPPS) Symposium   25 Jun 2016   
Novel Lysosomolytic Peptides to Achieve Cytoplasmic Distribution of Biomacromolecules [Invited]
FUTAKI Shiroh
The 16th Akabori Conference: Japanese-German Symposium On Peptide Science   24 May 2016   
Peptide Mediated Delivery of Bioactive Proteins into Cells [Invited]
FUTAKI Shiroh
8th AsiaTIDES   24 Feb 2016   
Membrane translocation of arginine-rich peptides and the effect of membrane curvature [Invited]
FUTAKI Shiroh
The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015)   19 Dec 2015   
Exploiting hemolytic amphiphilic peptides as a design template for cytosolic antibody delivery [Invited]
FUTAKI Shiroh
The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015)   17 Dec 2015   
Peptide mediated delivery of bioactive proteins into cells [Invited]
FUTAKI Shiroh
The 7th International Peptide Symposium   9 Dec 2015   
A novel lysosomolytic peptide designed from spider venom [Invited]
FUTAKI Shiroh
7th Peptide Engineering Meeting (PEM7-2015)   6 Dec 2015   
Converting a cytotoxic, hemolytic peptide to an intracellular delivery tool of bioactive proteins [Invited]
FUTAKI Shiroh
NEA & ASIAHORCs Joint Symposium on Chemical Biology   10 Nov 2015   
Peptide-based approaches for delivering exogenous molecules into cells [Invited]
FUTAKI Shiroh
International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery"   5 Jul 2015   
Peptide-based approaches for delivering exogenous molecules into cells [Invited]
FUTAKI Shiroh
International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery"   3 Jul 2015   
Asian Chemical Biology Conference 3 (ACBC3 2014) [Invited]
FUTAKI Shiroh
Peptide-based approaches for delivering exogenous molecules into cells   16 Dec 2014   
Peptide-based approaches for delivering exogenous molecules into cells [Invited]
FUTAKI Shiroh
Asian Chemical Biology Conference 3 (ACBC3 2014)   16 Dec 2014   
Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine [Invited]
FUTAKI Shiroh
The Sino-Japan Workshop on Chemical Biology   11 Oct 2014   
Extramembrane control of peptide/protein assembly [Invited]
FUTAKI Shiroh
Workshop on Artificial Photosynthesis: Engineering of Light-Harvesting Processes based on Peptide and Protein Science   6 Oct 2014   
Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine
FUTAKI Shiroh
Swiss-Japanese Chemical Biology Symposium 2014   2 Oct 2014   
Membrane translocation of arginine-rich cell-penetrating peptides and the effect of membrane curvature [Invited]
FUTAKI Shiroh
Karlsruher Institut für Technologie (KIT), special lecture   9 Sep 2014   
Engineering membrane curvatures by peptides [Invited]
FUTAKI Shiroh
15th Akabori Conference   8 Sep 2014   
Positive membrane curvature induced by epsin n-terminal peptide boosts translocation of oligoarginine through biological membranes: an approach towards curvature engineering
Shiroh Futaki, Sílvia Pujals, Tomo Murayama, Sergii Afonin, Hiroki Miyamae, Ikuhiko Nakase, Kazutami Sakamoto,Anne S. Ulrich
33rd European Peptide Symposium   31 Aug 2014   
Arginine-rich peptide vectors for intracellular delivery [Invited]
FUTAKI Shiroh
Ewha-Kyoto PI Research Meeting 2014   16 Jun 2014   
Peptide-based approaches for delivering exogenous molecules into cells [Invited]
FUTAKI Shiroh
The 3rd International Conference on MEXT Project of Integrated Research on Chemical Synthesis   11 Jan 2014   
Promotion of membrane translocation of cell-penetrating peptide octaarginine by curvature inducing peptide [Invited]
FUTAKI Shiroh
Chinese University of Hong Kong, Special lecture   27 Nov 2013   
CPP uptake mechanisms, endocytosis, direct membrane translocation [Invited]
FUTAKI Shiroh
A joint FEBS/Biochemical Society Lecture Course Cell-penetrating peptides: design, synthesis and applications   7 Oct 2013   
CXCR4 stimulates macropinocytosis
FUTAKI Shiroh
5th European Conference on Chemistry for Life Sciences   12 Jun 2013   
Arginine-rich cell-penetrating peptides and the effects of membrane curvature on their translocation through membranes [Invited]
FUTAKI Shiroh
Institut de Pharmacologie Moléculaire et Cellulaire seminar   7 Jun 2013   
CXCR4 stumulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV [Invited]
FUTAKI Shiroh
Recent Advance in Life Chemistry   19 Apr 2013   
Arginine-rich cell-penetrating peptides and their application to intracellular delivery [Invited]
FUTAKI Shiroh
The 111th General Meeting of the Korean Chemical Society   18 Apr 2013   
Peptide tools for controlling and analyzing cell functions
H24年度 筑波大学戦略イニシアティブ(A)「機能物質創製研究拠点」第3回国際シンポジウム 3rd International Symposium on Center for Creation of Functional Materials   10 Dec 2012   つくば
Creation of artificial epidermal growth factor receptor activated by coiled-coil peptides
The Sixth Peptide Engineering Meeting   2 Oct 2012   Atlanta
Activation of Biological Systems through an Artificial Receptor System via Dimerization of a Bivalent Leucine-Zipper Ligand
The 14th Akabori Conference   13 Sep 2012   ニセコ
Peptide tools for drug delivery and chemical biology
Chinese University of Hong Kong, Special lecture   25 Jun 2012   Hong Kong
Efficient internalization of arginine-rich cell-penetrating peptide through cell membranes
Satellite mini-workshop of IACIS 2012   12 May 2012   千葉(千葉科学大学)
Mechanisms to attain efficient cellular uptake of arginine-rich cell-penetrating peptides
Peptide Therapeutics Conference 2012   16 Feb 2012   Puerto Calero, Lanzarote, Spain
Creation of peptides that can alter their structure and function by external stimuli
Stockholm University, Neurochemistry seminar   19 Dec 2011   Stockholm
DNA Binding Properties of Ligand-Substituted Zinc Finger Proteins
第21回金属の関与する生体関連反応シンポジウム   30 May 2011   千葉(千葉大学)
CXCR4 is a receptor that stimulates cellular uptake of the R12 peptide
Peptide Vectors and Delivery of Therapeutics   20 May 2011   Tallinn, Estonia
Cell-penetrating peptides as a tool for intracellular delivery
2010環太平洋国際化学会議 Pacifichem2010 Session Title: Molecular Probes and Fluorophores for Cellular Imaging (#157)   20 Dec 2010   Honolulu, Hawaii, USA
Metal switch of peptide structure and function
2010環太平洋国際化学会議 Pacifichem2010 Session Title: Frontiers in Peptide Chemistry: Synthesis and Applications (#41)   19 Dec 2010   Honolulu, Hawaii, USA
Translocation of arginine-rich peptides through biological membranes
大阪大学蛋白質研究所セミナー The New Trend of Peptide Science in Asia and Oceania ペプチド科学 ?アジア・オセアニアの新潮流?   11 Dec 2010   吹田
Design and Creation of Metal-responsive DNA-binding Proteins
5th International Peptide Symposium in conjugation with 47th Japanese Peptide Symposium   4 Dec 2010   Kyoto
Peptide-mediated intracellular delivery ? chemical-biology and?drug-delivery aspects
Seminars for the Doctoral School as an Invited Professor   14 Oct 2010   Universit? Pierre et Marie Curi Paris, France
Arginine-rich peptides: the methods of internalization
National Museum of Natural History   8 Oct 2010   Paris, France
Physiological and physicochemical factors that achieve efficient?internalization of arginine-rich cell-penetrating peptides"
Seminars for the Doctoral School as an Invited Professor   7 Oct 2010   Universit? Pierre et Marie Curi Paris, France
Design of Functional Switching Peptides
Seminars for the Doctoral School as an Invited Professor Mini-synposium   4 Oct 2010   Universit? Pierre et Marie Curi Paris, France
Creation of peptides that can alter their structure and function by?the external stimuli
Seminars for the Doctoral School as an Invited Professor   30 Sep 2010   Universit? Pierre et Marie Curi Paris, France
Metal Switches of Peptide Functions
1st Asian Chemical Biology Conference   25 Jun 2010   Seoul, Korea
Chemical and Biological Factors that Stimulate Intracellular Delivery Using Arginine-Rich Cell-Penetrating Peptides
9th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and the International Workshop on Biomaterials   12 Jun 2010   Changshun, China
Cellular dynamics involved in the internalization of arginine-rich cell penetrating peptides
3rd Asia-Pacific International Peptide Symposium   10 Nov 2009   Jeju Island, Korea
Physiological and non-physiological factors involved in the internalization of arginine-rich peptides
Fifth Peptide Engineering Meeting (PEM5)   27 Oct 2009   Barcelona, Spain
Creation of Zinc Finger-Based Artificial Transcription Factors
Department Seminar, School of Parmacy, University of Maryland   21 Sep 2009   Baltimore, USA
Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides
PepVec2009 Meeting on "Intracellular Delivery of Therapeutic Molecules: From Bench to Bedside"   1 Sep 2009   Montpellier, France
Chemical and biological factors that contribute to the internalization of arginine-rich cell-penetrating peptides
第15回日本遺伝子治療学会   9 Jul 2009   Suita
Oligoarginine Vectors for Intracellular Delivery
2009 International Symposium & Annual Meeting of Korean Society for Microbiology and Biotechnology (KMB)   25 Jun 2009   Daejeon, Korea
Internalization of Arginine-rich Peptides into Cells
The 6th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and International Symposium on Biomaterials   26 Nov 2008   Sanya, China
Accelerated intracellular delivery using arginine-rich peptide vectors
4th Korea-Japan Workshop on Combinatorial Bioengineering   22 Nov 2008   Seoul, Korea
Arginine-rich peptides as a intracellular delivery vector
12 th Korean Peptide-Protein Society Symposium   21 Nov 2008   Seoul, Korea
Internalization mechanism of cell penetrating peptides
第34回 化学と生物シンポジウム Unconventional Pathway of Protein Secretion and Internalization: Mystery across Cell Membranes (タンパク質の分泌と細胞内導入の非定型的経路 細胞膜透過のミステリー)   27 Sep 2008   名古屋
Arginine-rich peptides as a vector of intracellular delivery
3rd International Workshop on Approaches to Single-Cell Analysis   12 Sep 2008   Zurich, Switzerland,
Cellular dynamics of cell penetrating peptides
2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008"   24 Jun 2008   Cardiff, UK
Controlling channel peptide assembly and gating by extramembrane conformational switch
Japanese-Swiss Symposium on Chemical Biology (JSCB)   25 Jun 2007   Lausanne, Switzerland
Membrane interaction and internalization of arginine-rich peptides
Stockholm University Neurochemistry Seminar   23 May 2007   Stockholm, Sweden
Arginine-rich peptides and their internalization mechanisms
Biochemical Society Focused Meeting Cell Penetrating Peptides   10 May 2007   Telford, UK
Cell penetrating peptides and their internalization mechanisms
Special Lecture at Welsh School of Pharmacy   8 May 2007   Cardiff, UK
Artificial ion channels gating by extramembrane conformation switch
Japan-Italy Research Cooperative Program: Japan-Italy Symposium of New Trends in Enzyme Science and Technology   16 Nov 2006   Nagoya
Arginine-rich peptides and the internalization mechanisms
International Mini Symposium “Membrane-permeable peptides: Chemistry, biology and therapeutic applications” (The 9th Peptide Forum; A satellite meeting of International Conference of 43rd Japanese Peptide Symposium/ 4th Peptide Engineering Meeting)   10 Nov 2006   Kyoto
Transmission of Extramembrane Conformational Switch into Channel Current; Design and Construction of Artificial Metal-gated Receptor Channel
International conference of 43rd Japanese Peptide Symposum/4th Peptide Engineering Meeting 第43回ペプチド討論会/第4回ペプチド工学国際会議   5 Nov 2006   Yokohama
Arginine-rich peptides as a deliver vector
The 11th Akabori Conference 2006 Japanese-German Symposium on Peptide Science   10 Sep 2006   Kloseter Banz, Germany
Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms
The first FIP-APSTJ joint workshop on gene delivery   11 Jul 2006   Sapporo
Membrane-permeable arginine-rich peptides and the interaction with cell membranes
10th Naples Workshop on Bioactive Peptides   13 Jun 2006   Naples, Italy
Peptide vectors for intracellular delivery
日本学術振興会 第2回日独先端科学(JGFos)シンポジウム2005 2nd Annual symposium Japanese-German Frontiers of Sciences   4 Nov 2005   逗子
Membrane-permeable arginine-rich peptides and the translocation mechanisms
Wenner-Gren Foundations international symposium “Cell-penetrating peptides and applications”   19 May 2005   Stockholm, Sweden
Arginine-rich peptides: aspects of membrane translocation
Delivery of macromolecules into cells using non-viral vectors   10 Jul 2004   Toronto, Canada
Arginine-rich peptides: mechanistic aspects of cellular uptake
第6回ファーマサイエンスフォーラム   8 May 2004   札幌
Arginine-rich peptides: aspects of translocation
Stockholm University, Dpt. Neurochemistry and Neurotoxicology講演会   17 Nov 2003   Stockholm, Sweden
Arginine-rich peptides: the aspects of membrane translocation
Cellular Drug Transport Mechanisms Workshop   14 Nov 2003   M?lndal, Sweden
Peptide-Based Ion-Channels as Prototypes for the Artificial Receptors and Sensors
21世紀COE 京都大学化学連携教育拠点 講演会 生物無機関連化学シンポジウム Symposium on Biological Inorganic and Related Chemistry   11 Aug 2003   京都
Potential of arginine-rich peptides as carriers for intracellular protein delivery
3rd Peptide Engineering Meeting (PEM-III)   17 Jul 2003   Boston
Translocation of Various Arginine-rich Peptides through the Cell Membranes: Potential of These Peptides as Carriers for Intracellular Protein Delivery
21 世紀COE「京都大学化学連携研究教育拠点」交流事業プログラム 韓国KAIST(Korea Advanced Institute of Science and Technology)?京都大学大学院理学研究科化学専攻連携研究拠点学術交流シンポジウム 現代分子科学の進展 Recent progress of advanced molecular science   19 Feb 2003   京都
Arginine-rich peptides: Potential of these peptides as carriers for intracellular delivery of bioactive molecules
Cellular transport strategies for targeting of epitopes, drugs and reporter molecules (CellTarget) workshop   6 Feb 2003   Budapest

Research Grants & Projects

 
Biofunctional Chemistry
Peptide Engineering
Cell Functional Chemistry