2013年7月4日
Preparation of optically active bicyclodihydrosiloles by a radical cascade reaction
Beilstein Journal of Organic Chemistry
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- 巻
- 9
- 号
- 開始ページ
- 1326
- 終了ページ
- 1332
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3762/bjoc.9.149
Bicyclodihydrosiloles were readily prepared from optically active enyne compounds by a radical cascade reaction triggered by tris(trimethylsilyl)silane ((Me3Si)3SiH). The reaction was initiated by the addition of a silyl radical to an α,β-unsaturated ester, forming an α-carbonyl radical that underwent radical cyclization to a terminal alkyne unit. The resulting vinyl radical attacked the silicon atom in an SHi manner to give dihydrosilole. The reaction preferentially formed trans isomers of bicyclosiloles with an approximately 7:3 to 9:1 selectivity. © 2013 Miyazaki et al.
- リンク情報
- ID情報
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- DOI : 10.3762/bjoc.9.149
- ISSN : 1860-5397
- SCOPUS ID : 84880865675
- Web of Science ID : WOS:000321301800001