住本英樹 (Hideki Sumimoto) - マイポータル - researchmap

基本情報

所属: 中村学園大学

学位: 医学博士

J-GLOBAL ID: 200901028549891802
researchmap会員ID: 1000041337

研究分野

2

経歴

4

1993年 - 1998年

九州大学助教授
1993年 - 1998年

九州大学
1985年 - 1993年

九州大学助手
1985年 - 1993年

Kyushu University, Research Assistant

学歴

4

MISC

32

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C

Yukiko Noda, Ryu Takeya, Shigeo Ohno, Seiji Naito, Takashi Ito, Hideki Sumimoto

Genes to Cells 6(2) 107-119 2001年
A Novel Superoxide-generating NAD(P)H Oxidase in Kidney

Journal of Biological Chemistry 276(2) 1417-1423 2001年
Arachidonic acid and phosphorylation synergistically induce a conformational change of p47(phox) to activate the phagocyte NADPH oxidase

A Shiose, H Sumimoto

JOURNAL OF BIOLOGICAL CHEMISTRY 275(18) 13793-13801 2000年5月
Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase

H Koga, H Terasawa, H Nunoi, K Takeshige, F Inagaki, H Sumimoto

JOURNAL OF BIOLOGICAL CHEMISTRY 274(35) 25051-25060 1999年8月
Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils

T Akasaki, H Koga, H Sumimoto

JOURNAL OF BIOLOGICAL CHEMISTRY 274(25) 18055-18059 1999年6月
Mechanism for Phosphorylation-induced Activation of the Phagocyte NADPH Oxidase Protein p47^phox : triple replacement of Serines 303,304 and 328 with aspartates disrupts intramolecular interaction in p47^phox, there by cativating th・・・

Journal of Biological Chemistry (274) 1999年
Association of the interleukin-4 receptor alpha chain with p47(phox), an activator of the phagocyte NADPH oxidase in B cells

K Izuhara, Y Arinobu, H Sumimoto, H Nunoi, R Takeya, K Higuchi, K Takeshige, N Hamasaki, N Harada

MOLECULAR IMMUNOLOGY 36(1) 45-52 1999年1月
Purification and characterization of recombinant human neutrophil leukotriene B-4 omega-hydroxylase (cytochrome p450 4F3)

Y Kikuta, E Kusunose, H Sumimoto, Y Mizukami, K Takeshige, T Sakaki, Y Yabusaki, M Kusunose

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 355(2) 201-205 1998年7月
Anionic amphiphile-independent activation of the phagocyte NADPH oxidase in a cell-free system by p47(phox) and p67(phox), both in C terminally truncated forms - Implication for regulatory Src homology 3 domain-mediated interactions

K Hata, T Ito, K Takeshige, H Sumimoto

JOURNAL OF BIOLOGICAL CHEMISTRY 273(7) 4232-4236 1998年2月
The PC motif: a novel and evolutionarily conserved sequence involved in interaction between p40(phox) and p67(phox), SH3 domain-containing cytosolic factors of the phagocyte NADPH oxidase

R Nakamura, H Sumimoto, K Mizuki, K Hata, T Ago, S Kitajima, K Takeshige, Y Sakaki, T Ito

EUROPEAN JOURNAL OF BIOCHEMISTRY 251(3) 583-589 1998年2月
Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins - Involved in the phagocyte NADPH oxidase complex

K Mizuki, K Kadomatsu, K Hata, T Ito, QW Fan, Y Kage, Y Fukumaki, Y Sakaki, K Takeshige, H Sumimoto

EUROPEAN JOURNAL OF BIOCHEMISTRY 251(3) 573-582 1998年2月
Molecular basis of hereditary methemoglobinemia, types I and (]G0002[) : two novel mutations in the NADPH-Cytochrome b5 reductase gene.

British Journal of Haematology (103) 922-930 1998年
Roles for proline-rich regions of p47^phox and p67^phox in the phagocyte NADPH oxidase activation in vitro. (共著)

Biochemical and Biophysical Research Communications 241(2) 226-231 1997年
Assembly and activation of the phagocyte NADPH oxidase - Specific interaction of the N-terminal Src homology 3 domain of p47(phox) with p22(phox) is required for activation of the NADPH oxidase

H Sumimoto, K Hata, K Mizuki, T Ito, Y Kage, Y Sakaki, Y Fukumaki, M Nakamura, K Takeshige

JOURNAL OF BIOLOGICAL CHEMISTRY 271(36) 22152-22158 1996年9月
Molecular analysis of hereditary methemo-globinemia : the compound heterozygosity for two novel mutations in the NADH-cytochrome b5 reductase gene results in the generalized type(共著)

Blood 88 3208-3215 1996年
An SH3 domain-mediated interaction between the phagocyte NADPH oxidase factors p40^phox with p47^phox. (共著)

FEBS Letters 385(3) 229-232 1996年
Effects of L-arginine analogues on vasomotion of isolated porcine coronary arteries (共著)

American Journal of Physiology 268 H1966-H1972 1995年
ω-Oxidation of lipoxin B_4 by rat liver : identification of an ω-carboxy metabolite of lipoxin B_4

MIZUKAMI Y.

Eur. J. Biochem. 224(3) 959-965 1994年
Cloning and sequencing of the cDNA encoding human glutaredoxin (共著)

Biochemica et Biophysica Acta 1218 229-231 1994年
Role of Src homology 3(SH3) domains in assembly and activation of the phagocyte NADPH oxidase (共著)

Proceedings of the National Academy of Sciences of the United States of America 91(12) 5345-5349 1994年

もっとみる

書籍等出版物

2

Membrane translocation of cytosolic factors in activation of the phagocyte NADPH oxidase : Role of protein-protein interaction(共著)

Membrane Proteins : Structure, Function and Expression Control, Kyushu University Press/S. Karger AG 1997年
Cytochrome b₅₅₈ : A Flavocytochrome Comprising the Complete Electron-Transporting Apparatus of Phagocyte NADPH Oxidase (共著)

Regulation of Heme Protein Synthesis, AlphaMed Press 1994年

所属学協会

2

共同研究・競争的資金等の研究課題

4