The homogeneous oxidation Of isopentane was investigated in, the vapor phase. The main products were oxygenated compounds (3-methyltetrahydrofuran, 2-propyloxirane, 2-ethyl-2-methyloxirane, 2,2,3-trimethyloxirane, acetone and acetaldehyde), and isopentenes. The yields of oxygenated compounds and isopentenes; depended on the residence time, indicating that the oxygenated compounds formed through isopentenes, from isopentane. It is concluded from the results of the vapor-phase oxidation of isopentenes (3-methyl-1-butene, 2-methyl-2-butene and 2-methyl-1-butene) that 3-methyltetrahydrofuran and 2-propyloxirane might be formed through 3-methyl-1-butene, 2,2,3-aimethyloxirane and acetone through 2-methyl-2-butene, and 2-edlyl-2-methyloxirane through 2-methyl-1-butene in the vapor-phase oxidation of isopentane.