HATAKEYAMA Tomomitsu

J-GLOBAL         Last updated: Apr 15, 2019 at 11:19
 
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Name
HATAKEYAMA Tomomitsu
URL
http://www.ch.nagasaki-u.ac.jp/bio/
Affiliation
Nagasaki University
Section
Graduate school of Engineering
Job title
Professor
Degree
Doctor of Agriculture(Kyushu University)

Research Areas

 
 

Academic & Professional Experience

 
Apr 2011
 - 
Today
Professor, Graduate School of Engineering, Nagasaki University
 
1996
 - 
2005
 Associate Professor,Applied Chemistry,Faculty of Engineering,Nagasaki University
 
2005
   
 
 Professor,Applied Chemistry,Faculty of Engineering,Nagasaki University
 
Jun 1990
 - 
Mar 1996
Assistant Professor, Faculty of Agriculture, Kyushu University
 
1990
 - 
1996
 Research Associate,Kyushu University
 

Education

 
 
 - 
1986
Graduate School, Division of Agriculture, Kyushu University
 
 
 - 
1981
Faculty of Agriculture, Kyushu University
 

Awards & Honors

 
1997
The Japan Bioscience, Biotechnology, and Agrochemistry; Society Award for Encouragement of Young Scientists
 

Published Papers

 
Unno H, Itakura S, Higuchi S, Goda S, Yamaguchi K, Hatakeyama T
Protein science : a publication of the Protein Society   28(4) 766-778   Apr 2019   [Refereed]
Unno H, Nakamura A, Mori S, Goda S, Yamaguchi K, Hiemori K, Tateno H, Hatakeyama T
Scientific reports   8(1) 11516   Aug 2018   [Refereed]
Ca2+-Independent Carbohydrate-Recognition of the C-Type Lectins, Spl-1 and Spl-2, from the Bivalve Saxidomus Purpuratus and their Dimerization Properties
Higuchi Shuhei, Unno Hideak, Goda Shuichiro, Hatakeyama Tomomitsu
PROTEIN SCIENCE   27 136-137   Nov 2018   [Refereed]
Hatakeyama T, Ichise A, Unno H, Goda S, Oda T, Tateno H, Hirabayashi J, Sakai H, Nakagawa H
Protein science : a publication of the Protein Society   26(8) 1574-1583   Aug 2017   [Refereed]
Nagao T, Masaki R, Unno H, Goda S, Hatakeyama T
Bioscience, biotechnology, and biochemistry   80(10) 1966-1969   Oct 2016   [Refereed]
Unno H, Matsuyama K, Tsuji Y, Goda S, Hiemori K, Tateno H, Hirabayashi J, Hatakeyama T
Scientific reports   6 29135   Jul 2016   [Refereed]
Crystal structure of a novel Ca2+-dependent lectin GJL-I from the sea anemone Gyractis japonica and its carbohydrate-recognition mechanism
Nakamura Azusa, Unno Hideaki, Goda Shuichiro, Hatakeyama Tomomitsu
PROTEIN SCIENCE   25 158   Oct 2016   [Refereed]
Hatakeyama T, Higashi E, Nakagawa H
Toxicon : official journal of the International Society on Toxinology   108 46-52   Dec 2015   [Refereed]
Structure and carbohydrate-binding properties of a C-type lectin SPL with novel carbohydrate-recognition motifs
Itakura Shuhei, Unno Hideaki, Goda Shuichiro, Hatakeyama Tomomitsu
PROTEIN SCIENCE   25 154-155   Oct 2016   [Refereed]
Moriuchi H, Unno H, Goda S, Tateno H, Hirabayashi J, Hatakeyama T
Biochimica et biophysica acta   1850(7) 1457-1465   Jul 2015   [Refereed]
Hatakeyama T, Ichise A, Yonekura T, Unno H, Goda S, Nakagawa H
Toxicon : official journal of the International Society on Toxinology   94 8-15   Feb 2015   [Refereed]
Unno H, Goda S, Hatakeyama T.
Journal of Biological Chemistry   289(18) 12805-12812   May 2014   [Refereed]
Hatakeyama Tomomitsu, Goda Shuichiro, Unno Hideaki
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY   28(161) E55-E60   May 2016   [Refereed]
Kato Y, Kochi K, Unno H, Goda S, Hatakeyama T
Bioscience, biotechnology, and biochemistry   78(11) 1906-1909   Nov 2014   [Refereed]
Hisamatsu K, Nagao T, Unno H, Goda S, Hatakeyama T.
Biochimica et Biophysica Acta - General Subjects   1830(8) 4211-4217   Aug 2013   [Refereed]
Goda S, Sadakata H, Unno H, Hatakeyama T.
Bioscience, Biotechnology and Biochemistry   77(3) 679-681   Mar 2013   [Refereed]
Alteration of the carbohydrate-binding specificity of the C-type lectin CEL-I by site-directed mutagenesis
Moriuchi Hiromi, Unno Hideaki, Goda Shuichiro, Hatakeyama Tomomitsu
GLYCOBIOLOGY   24(11) 1140-1141   Nov 2014   [Refereed]
Unno H, Hisamatsu K, Nagao T, Tateya Y, Matsumoto N, Goda S, Hatakeyama T.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications   69(4) 416-420   Apr 2013   [Refereed]
Expression and characterization of the recombinant lectin SUL-1 derived from the venom of the sea urchin Toxopneustes pileolus
Ichise Ayaka, Unno Hideaki, Goda Shuichiro, Nakagawa Hideyuki, Hatakeyama Tomomitsu
GLYCOBIOLOGY   24(11) 1141   Nov 2014   [Refereed]
Hatakeyama T, Ishimine T, Baba T, Kimura M, Unno H, Goda S.
Protein and Peptide Letters   20(7) 796-801   Jul 2013   [Refereed]
Hatakeyama T, Karino R, Terai Y, Kimura M, Unno H, Goda S.
Bioscience, Biotechnology and Biochemistry   76(10) 1999-2001   Oct 2012   [Refereed]
Hatakeyama T
Methods in molecular biology (Clifton, N.J.)   1200 165-171   2014   [Refereed]
Niidome T, Matsuyama N, Kunihara M, Hatakeyama T, Aoyagi H.
Bulletin of the Chemical Society of Japan   78(3) 473-476   2005   [Refereed]
Shiba K, Hatakeyama T.
Polymer Preprints, Japan   54(2)    2005   [Refereed]
Property and antibacterial activity of dendritic and linear cationic peptides
Aoyagi Haruhiko, Hirano Akira, Niidome Takuro, Hatakeyama Tomomitsu
Peptide Revolution: Genomics, Proteomics & Therapeutics   970-971   2004   [Refereed]
Satoh F, Nakagawa H, Yamada H, Nagasaka K, Nagasaka T, Araki Y, Tomihara Y, Nozaki M, Sakuraba H, Ohshima T, Hatakeyama T, Aoyagi H.
Journal of Natural Toxins   11(4) 297-304   2002   [Refereed]
Niidome T, Urakawa M, Ohmori N, Hatakeyama T, Wada A, Hirayama T, Aoyagi H.
Proceedings of the Controlled Release Society   (26) 503-504   1999   [Refereed]
Oda T, Shinmura N, Nishioka Y, Komatsu N, Hatakeyama T, Muramatsu T.
Journal of Biochemistry   125(4) 713-720   1999   [Refereed]
Niidome T, Anzai S, Sonoda J, Tokunaga Y, Nakahara M, Hatakeyama T, Aoyagi H.
Journal of Peptide Science   5(7) 298-305   1999   [Refereed]
Hatakeyama T, Kamine T, Konishi Y, Kuwahara H, Niidome T, Aoyagi H.
Bioscience, Biotechnology and Biochemistry   63(7) 1312-1314   1999   [Refereed]
Yoshida K, Ohmori N, Mukai Y, Niidome T, Hatakeyama T, Aoyagi H.
Journal of Peptide Science   5(8) 360-367   1999   [Refereed]
Ohmori N, Niidome T, Hatakeyama T, Mihara H, Aoyagi H.
Journal of Peptide Research   51(2) 103-109   1998   [Refereed]
Hatakeyama T.
Nippon Nogeikagaku Kaishi   71(11) 1147-1152   1997   [Refereed]
Hirayama T, Yahiro K, Kimura M, Okamoto K, Padilla P.I, Wada A, Niidome T, Hatakeyama T, Aoyagi H.
Japanese Journal of Medical Science and Biology   50(4-5) 198-199   1997   [Refereed]
Hatakeyama T, Kuwahara H, Sato T, Niidome T, Aoyagi H, Fujisawa T.
Japanese Journal of Medical Science and Biology   50(4-5)    1997   [Refereed]
Hatakeyama T, Kohzaki H, Yamasaki N.
Analytical Biochemistry   207(2)    1992   [Refereed]
Kimura M, Arndt E, Kromer W, Kimura J, Hatakeyama T, Hatakeyama T.
Journal of Protein Chemistry   7(3) 248-249   1988   [Refereed]

Misc

 
Ueno Mikinori, Yamanishi Tomohiro, Hatakeyama Tomomitsu, Yamaguchi Kenichi, Oda Tatsuya
Japanese Journal of Food Chemistry and Safety   20(3) 196-202   2013
Lycopene existing in tomato is a nonprovitamin carotenoid with potent antioxidant properties. In addition to the antioxidant activities, lycopene is know to show anti-inflammatory effects through the inhibition of secretion of proinflammatory agen...
HATAKEYAMA Tomomitsu
Seibutsu Butsuri   49(2) 75-79   Mar 2009
CEL-III is a Ca2+-dependent hemolytic lectin isolated from the sea cucumber Cucumaria echinata. X-ray crystallographic analysis revealed that CEL-III is composed of two ricin-like carbohydrate-binding domains (domain 1/2) and an ...
UCHIDA Tatsuya, HATAKEYAMA Tomomitsu, KUSUNOKI Masami
Nihon Kessho Gakkaishi   48(4) 290-295   Aug 2006
CEL-III is a Ca2+-dependent animal lectin from the sea cucumber, Cucumaria echinata, which shows binding specificity for galactose-containing carbohydrates and exhibits hemolytic and hemagglutinating activities. We have determin...
Ricin D-saccharide interaction as studied by ultraviolet difference spectroscopy
Yamasaki, N., Hatakeyama, T., and Funatsu, G.
J. Biochem.   98(6) 1555-1560   1985

Books etc

 
Sequence comparison and evolution of ribosomal proteins and their genes
1990   
Animal Lectins (G.R. Vasta and H. Ahmed, eds.)
CRC Press   2008   

Conference Activities & Talks

 
Cytotoxic mechanism of a GalNAc-specific C-type lectin CEL-I isolated from Holothuroidea (Cucumaria echinata) in MDCK cells
2004   
Characterization of recombinant CEL-IV, an invertebrate C-type lectin, expressed in Escherichia coli using an artificial synthetic gene
2004   
Characterization of the putative carbohydrate-binding domain of a dendritic cell surface receptor
2004   
X-ray crystallographic analysis of a complex of an α-galactoside specific C-type lectin CEL-IV and melibiose
2005   
Carbohydrate-recognition mechanism of an invertebrate C-type lectin CEL-IV revealed by X-ray crystallographic analysis
2005   

Works

 
Analysis of oligomerization of hemolytic lectin by small angle X-ray scattering
1998
X-ray structural analysis of Ca2+-dependent lectins from marine invertebrate
1999

Research Grants & Projects

 
Study on Biologically Active Proteins of Marine Invertebrates
Project Year: 1989   
Study on Structure and Function of Protein Toxins
Project Year: 1989   
Development of New Functions of Biologically Acitive Peptides
Project Year: 1996