MISC

2003年10月

Stripes, spots, or reversed spots in two-dimensional Turing systems

JOURNAL OF THEORETICAL BIOLOGY
  • H Shoji
  • ,
  • Y Iwasa
  • ,
  • S Kondo

224
3
開始ページ
339
終了ページ
350
記述言語
英語
掲載種別
DOI
10.1016/S0022-5193(03)00170-X
出版者・発行元
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD

Two-dimensional Turing models can generate stationary striped patterns or spotted patterns, and are used to explain the body pattern formation of animals. We studied the effects of the choice of reaction terms on pattern selection, i.e., which pattern is likely to be formed. We examined in detail a model with linear reaction terms and additional constraint terms that confine two variables within a finite range. In the one-dimensional model, a periodic stationary pattern can be formed only when the activator level is constrained both from below and from above. In the two-dimensional model, the relative distance of the equilibrium level of the activator between the upper and lower limitations determines the pattern selection. Striped patterns are produced when the equilibrium is equally distant from the upper and the lower limitations, but spotted patterns are produced when the equilibrium is clearly closer to one than to the other of two limitations. We then examined models with nonlinear reaction terms, including both activator-inhibitor and activator-depletion substrate type models; we attempted to explain the pattern selection of these nonlinear models based on the results of linear models with constraints. The distribution of the activator level is skewed positively and negatively for spotted patterns and reversed spotted patterns, respectively. In contrast, the skew of the distribution of the activator level was close to zero in the case of striped patterns. This observation provides a heuristic argument of how the location of the equilibrium between the constraints leads to pattern selection. (C) 2003 Elsevier Ltd. All rights reserved.

リンク情報
DOI
https://doi.org/10.1016/S0022-5193(03)00170-X
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000185303900007&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/S0022-5193(03)00170-X
  • ISSN : 0022-5193
  • eISSN : 1095-8541
  • Web of Science ID : WOS:000185303900007

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