1996- National Institute for Basic Biology, Professor 1987-1996 Department of Molecular Biology, Graduate School of Medical Sciences, Kyushu University, Instructor 1986 Department of Biology, Faculty of Science, Kyushu University, Assistant Prof.
An orphan nuclear receptor, Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1), is essential for the development and function of steroidogenic tissues. To examine the transcriptional regulation of Ad4BP/SF-1, two-hybrid screening was performe...
Hirofumi Mizusaki, Ken Kawabe, Tokuo Mukai, Etsuko Ariyoshi, Megumi Kasahara, Hidefumi Yoshioka, Amanda Swain, Ken Ichirou Morohashi
Mol. Endocrinol. 17 507-519 Apr 2003
Dax-1 [dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (NR0B1)] is an orphan nuclear receptor acting as a suppressor of Ad4 binding protein/steroidogenic factor 1 [Ad4BP/SF-1 (NR5A1)] and as a...
It has been more than 150 years since the physiological function of androgen was reported for the first time in fowl. This finding has served as a basis for many studies focusing on steroid hormones from various aspects. These studies have signifi...