堀内正公 (Seikoh Horiuchi) - マイポータル - researchmap

基本情報

所属: 旧所属熊本大学大学院医学薬学研究部総合医薬科学部門教授

学位: 医学博士

J-GLOBAL ID: 200901006733019324
researchmap会員ID: 1000044470

外部リンク: http://www.medic.kumamoto-u.ac.jp/dept/biochem2/index.html

研究キーワード

4

研究分野

2

経歴

4

学歴

4

委員歴

5

MISC

187

Reactive oxygen species accelerate production of vascular endothelial grown factor by advanced glycation end products in Raw264.7 mouse macrophages

FRBM 2002年
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients

N Shibata, R Nagai, K Uchida, S Horiuchi, S Yamada, A Hirano, M Kawaguchi, T Yamamoto, S Sasaki, M Kobayashi

BRAIN RESEARCH 917(1) 97-104 2001年10月
CD36, a Member of the Class B Scavenger Receptor Family, as a Receptor for Advanced Glycation End Products

Nobutaka Ohgami, Ryoji Nagai, Mamoru Ikemoto, Hiroyuki Arai, Akihiko Kuniyasu, Seikoh Horiuchi, Hitoshi Nakayama

Journal of Biological Chemistry 276(5) 3195-3202 2001年2月2日
The role of galectin-3 in endocytosis of advanced glycation end products and modified low density lipoproteins

WQ Zhu, H Sano, R Nagai, K Fukuhara, A Miyazaki, S Horiuchi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 280(4) 1183-1188 2001年2月
Induction of acyl-coenzyme A : cholesterol acyltransferase-1 by 1,25-dihydroxyvitamin D-3 or 9-cis-retinoic acid in undifferentiated THP-1 cells

KK Maung, A Miyazaki, H Nomiyama, CCY Chang, TY Chang, S Horiuchi

JOURNAL OF LIPID RESEARCH 42(2) 181-187 2001年2月
CD36, a member of class B scavenger receptor family, is a receptor for advanced glycation end products

Ann N. Y. Acad. Sci 947 2001年
CD36 serves as a receptor for advanced glycation endproducts (AGE)

Journal of Diabetes and Its Complications 16 1-4 2001年
Formation of advanced glycation end product-modified superoxide dismutase-1 (SOD1) is one of the mechanisms responsible for inclusions common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutation, and the transgenic mice expressing・・・

Neuropathol 21(1) 67-81 2001年
Immunohisochemical distribution and quantitative biochemical detection of advanced glycation end products in fetal and adult rats and in rats with streptozotocin-induced diabetes

Lab. Invest 81 845-861 2001年
) Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products

J. Biol. Chem 276(16) 13348-13355 2001年
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesi

Cardiovasc. Res 49 466-475 2001年
Tissue caboxymethyllysine in diabetic and non-diabetic patients with chronic renal failure: relevance to glycoxidation damage

Nephron 88 30-35 2001年
In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques

Y Imanaga, N Sakata, S Takebayashi, A Matsunaga, J Sasaki, K Arakawa, R Nagai, S Horiuchi, H Itabe, T Takano

ATHEROSCLEROSIS 150(2) 343-355 2000年6月
Increased levels of advanced glycosylation end products in the kidney and liver from spontaneously diabetic Chinese hamsters determined by immunochemical assay

A Abiko, M Eto, Makino, I, N Araki, S Horiuchi

METABOLISM-CLINICAL AND EXPERIMENTAL 49(5) 567-573 2000年5月
Advanced glycation end product in familial amyloidotic polyneuropathy (FAP)

N Nyhlin, Y Ando, R Nagai, O Suhr, M El Sahly, H Terazaki, S Yamashita, M Ando, S Horiuchi

JOURNAL OF INTERNAL MEDICINE 247(4) 485-492 2000年4月
Macrophage proliferation in atherosclerosis

Current Opinion in Lipidology 2000年
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral Sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with G85R mutation.

Acta Neuropathol 2000年
Possible involvement of altered RGD sequence in reduced adhesive and spreading activities of advanced glycation end product-modified fibronectin to vascular smooth muscle cells

Connective Tissue Research 2000年
Nonoxidative protein glycation is implicated in familiar ALS with SOD1 mutation.

Acta Neuropathol 2000年
Tissue carboxymethyllysine in diabetic and non-diabetic patients with chronic renal failure: relevance to glycoxidation damage.

Nephron 2000年

もっとみる

書籍等出版物

5

Advanced glycation end products of the Maillard reaction : Structures and biological significance

The post-translational modification of proteins 1992年
Biologica recognition of advanced end product of the Maillard reaction

The Maillard Reaction in Food Processing, Human Nutrition and Physiology 1990年
Separation of protein-secreting from other membrane domains of Bacillus subtilis

Protein Transport and Secretion 1984年
Inter-organ cooperation in enzymic processing and membrane transport of glutathione S-conjugates

Glutathione : Storage, Transport and Turnover in Mammals 1983年
Subunit Structure of rat kidney γ-glutamyl transpeptidase and its topology on brush border membrane

Frontiers in Protein Chemistry 1980年

所属学協会

5

Works(作品等)

4

共同研究・競争的資金等の研究課題

6