MISC

2002年12月

Skin manifestations of arsenicosis in two villages in Bangladesh

INTERNATIONAL JOURNAL OF DERMATOLOGY
  • T Kadono
  • ,
  • T Inaoka
  • ,
  • N Murayama
  • ,
  • K Ushijima
  • ,
  • M Nagano
  • ,
  • S Nakamura
  • ,
  • C Watanabe
  • ,
  • K Tamaki
  • ,
  • R Ohtsuka

41
12
開始ページ
841
終了ページ
846
記述言語
英語
掲載種別
DOI
10.1046/j.1365-4362.2002.01668.x
出版者・発行元
BLACKWELL PUBLISHING LTD

Background Arsenic contamination in groundwater affects 35 million people in Bangladesh, but the prevalence of arsenic contamination in local communities remains to be clarified. As skin manifestations are sensitive markers of arsenicosis, we examined the skin of adults and adolescents in two villages to elucidate the severity of arsenicosis.
Methods Five hundred and sixty-one villagers were randomly selected for the evaluation of their skin. Three indicators, i.e. keratosis on the soles, keratosis on the palms, and melanosis and hypopigmentation on the trunk, were quantified for analysis.
Results More than 50% of the villagers showed some skin manifestations due to arsenicosis. Keratosis on the soles was the most sensitive marker for the detection of arsenicosis at an early stage. Interestingly, the skin manifestations were more severe in males than in females. There was no correlation between the age and the severity of skin manifestations.
Conclusions The prevalence of arsenicosis was quite high and males were more vulnerable to arsenic contamination. Using skin manifestations, especially keratosis on the soles, as useful markers to detect and evaluate arsenicosis, it is clear that there is an urgent need to assess the exact prevalence and severity of arsenicosis in the population of Bangladesh in order to take measures to treat and control this problem.

Web of Science ® 被引用回数 : 54

リンク情報
DOI
https://doi.org/10.1046/j.1365-4362.2002.01668.x
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000179922100003&DestApp=WOS_CPL

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