土屋博紀 (Hironori Tsuchiya) - マイポータル

基本情報

J-GLOBAL ID: 200901058746459706
researchmap会員ID: 1000099275

研究キーワード

研究分野

論文

Review- Interaction of local anesthetics with biomembranes consisting of phospholipids and cholesterol: mechanistic and clinical implications for anesthetic and cardiotoxic effects

TSUCHIYA Hironori

Anesthesiology Research and Practice 2013 1-18 2013年9月査読有り
Increasing Membrane Interactions of Local Anaesthetics as Hypothetic Mechanism for Their Cardiotoxicity Enhanced by Myocardial Ischaemia

Hironori Tsuchiya, Maki Mizogami, Kenji Shigemi

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 111(5) 303-308 2012年11月査読有り
Plant components exhibit pharmacological activities and drug interactions by acting on lipid membranes

TSUCHIYA Hironori

Pharmacognocy Communications 2 58-71 2012年11月査読有り
Inhibition of Membrane Effects of General Anesthetic Propofol by Benzodiazepine Inverse Agonist Tetrahydro-beta-carboline

H. Tsuchiya

INTERNATIONAL JOURNAL OF PHARMACOLOGY 8(6) 542-548 2012年8月査読有り
Cardiotoxic local anesthetics increasingly interact with biomimetic membranes under ischemia-like acidic conditions

Hironori Tsuchiya, Maki Mizogami, Takahiro Ueno, Kenji Shigemi

Biological and Pharmaceutical Bulletin 35(6) 988-992 2012年6月査読有り
The membrane interaction of drugs as one of mechanisms for their enantioselective effects.

Tsuchiya Hironori, Mizogami Maki, 朝日大学, 朝日大学

Medical hypotheses 79(1) 65-97 2012年5月査読有り
R(+)-, Rac-, and S(-)-Bupivacaine Stereostructure-Specifically Interact with Membrane Lipids at Cardiotoxically Relevant Concentrations

Hironori Tsuchiya, Maki Mizogami

ANESTHESIA AND ANALGESIA 114(2) 310-312 2012年2月査読有り

MISC

Antioxidant Activity Analysis by Liposomal Membrane System and Application to Anesthetics

Hironori Tsuchiya, Takahiro Ueno, Maki Mizogami, Ko Takakura

ANALYTICAL SCIENCES 24(12) 1557-1562 2008年12月
Peroxynitrite affects lidocaine by acting on membrane-constituting lipids

Takahiro Ueno, Maki Mizogami, Ko Takakura, Hironori Tsuchiya

JOURNAL OF ANESTHESIA 22(4) 475-478 2008年11月
Anti proliferative effects associated with membrane lipid interaction of green tea catechins

Hironori Tsuchiya, Toshiyuki Tanaka, Motohiko Nagayama

JOURNAL OF HEALTH SCIENCE 54(5) 576-580 2008年10月
Garlic allyl derivatives interact with membrane lipids to modify the membrane fluidity

Hironori Tsuchiya, Motohiko Nagayama

JOURNAL OF BIOMEDICAL SCIENCE 15(5) 653-660 2008年9月
Stereospecific interaction of bupivacaine enantiomers with lipid membranes

Maki Mizogami, Hironori Tsuchiya, Takahiro Ueno, Masanori Kashimata, Ko Takakura

REGIONAL ANESTHESIA AND PAIN MEDICINE 33(4) 304-311 2008年7月
Membrane effect of lidocaine is inhibited by interaction with peroxynitrite

Takahiro Ueno, Maki Mizogami, Ko Takakura, Hironori Tsuchiya

JOURNAL OF ANESTHESIA 22(1) 96-99 2008年2月
Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite

Takahiro Ueno, Hironori Tsuchiya, Maki Mizogami, Ko Takakura

Journal of Inflammation Research 1 41-48 2008年
Membrane Activity-Guided Isolation of Antiproliferative and Antiplatelet Constituent from Evodiopanax innovans

Hironori Tsuchiya, Toshiyuki Tanaka, Motohiko Nagayama, Masayoshi Oyama, Munekazu Iinuma

Natural Product Communications 8 809-814 2008年
Membrane interactivity of charged local anesthetic derivative and stereoselectivity in membrane interaction of local anesthetic enantiomers

Hironori Tsuchiya, Maki Mizogami

Local and Regional Anesthesia 1 1-9 2008年
Interaction of local anaesthetics with lipid membranes under inflammatory acidic conditions

H. Tsuchiya, M. Mizogami, T. Ueno, K. Takakura

Inflammopharmacology 15(4) 164-170 2007年8月
Cell growth inhibition by membrane-active components in brownish scale of onion

Miyuki Furusawa, Hironori Tsuchiya, Motohiko Nagayama, Toshiyuki Tanaka, Masayoshi Oyama, Tetsuro Ito, Munekazu Iinuma, Hiroshi Takeuchi

JOURNAL OF HEALTH SCIENCE 52(5) 578-584 2006年10月
Reversed-phase liquid chromatographic retention and membrane activity relationships of local anesthetics

H Tsuchiya, M Mizogami, K Takakura

JOURNAL OF CHROMATOGRAPHY A 1073(1-2) 303-308 2005年5月
High-performance liquid chromatographic analysis of beta-carbolines in human scalp hair

H Tsuchiya

JOURNAL OF CHROMATOGRAPHY A 1031(1-2) 325-330 2004年3月
A new flavonol glucoside from onion

M Furusawa, T Tanaka, K Nakaya, M Iinuma, H Tuchiya

HETEROCYCLES 57(11) 2175-2177 2002年11月
Membrane-rigidifying effects of anti-cancer dietary factors

H Tsuchiya, M Nagayama, T Tanaka, M Furusawa, M Kashimata, H Takeuchi

BIOFACTORS 16(3-4) 45-56 2002年
Comparative effects of flavonoidal phytochemicals on membrane fluidity and tumor cell growth

Revista de Fitoterapia 2(51) 137 2002年
Membrane effects of ropivacaine compared with those of bupivacaine and mepivacaine

Fundamental & Clinical Pharmacology 16, 325-330 2002年
Biphasic membrane effects of capsaicin, an active component in Capsicum species

H Tsuchiya

JOURNAL OF ETHNOPHARMACOLOGY 75(2-3) 295-299 2001年5月
Structure-specific membrane-fluidizing effect of propofol

H Tsuchiya

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 28(4) 292-299 2001年4月
Stereospecificity in membrane effects of catechins

H Tsuchiya

CHEMICO-BIOLOGICAL INTERACTIONS 134(1) 41-54 2001年3月

もっとみる

書籍等出版物

講演・口頭発表等

Novel pharmacological approach to medicinal effects of Allium vegetables: The interactions of organosulfur and flavonoid constituents with membrane lipids

7th Joint Meeting of AFERP, ASP, GA, PSE and SIF (Athens, Greece) 2008年
MECHANISTIC MEMBRANE-INTERACTION OF LOCAL ANAESTHETICS FOR THEIR STRUCTURE-DEPENDENT CARDIOTOXIC EFFECTS

Hong Kong Academy of Medicine 15th Anniversary Congress (Hong Kong, China) 2008年
VERIFICATION OF THE TISSUE ACIDIFICATION HYPOTHESIS FOR LOCAL ANESTHETIC FAILURE ASSOCIATED WITH ACUTE INFLAMMATION

IARS 81st Clinical and Scientific Congress (Orlando, USA) 2007年
ACIDOSIS RESPONSIBLE FOR INFLAMMATORY INTERFERENCE OF LOCAL ANESTHESIA?

17th IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine (Amsterdam, The Netherlands) 2007年
REEXAMINATION OF MECHANISTIC INTERACTION OF LOCAL ANESTHETICS WITH MEMBRANE LIPID BILAYERS

IARS 80th Clinical and Scientific Congress (San Francisco, USA) 2006年
Hypothetic Participation of Beta-Carbolines in Neuropsychiatric Disorders

World Psychiatric Association International Congress 2006 (Istanbul, Turkey) 2006年
Interactions of Landiolol and Beta-Blockers with Membrane Lipid Bilayers

8th America Japan Anesthesia Congress (Honolulu, USA) 2005年
MEMBRANE EFFECTS OF LANDIOLOL COMPARED WITH THOSE OF ESMOLOL AND PROPRANOLOL

IARS 79th Clinical and Scientific Congress (Honolulu, USA) 2005年
REVERSED-PHASE LIQUID CHROMATOGRAPHIC RETENTION AND MEMBRANE ACTIVITY RELATIONSHIPS OF LOCAL ANESTHETICS

28th International Symposium and Exhibition on High Performance Liquid Phase Separations and Related Techniques (Philadelphia, USA) 2004年
HPLC ANALYSIS OF BETA-CARBOLINES IN HUMAN SCALP HAIR

27th International Symposium and Exhibition on High Performance Liquid Phase Separations and Related Techniques (Nice, France) 2003年
Tumor Cell Growth-Inhibitory Effects of Green Tea Catechins Associated with Membrane Rigidification

3rd International Symposium on Natural Drugs (Naples, Italy) 2003年
Comparative effects of flavonoidal phytochemicals on membrane fluidity and tumor cell growth

50th Annual Congress of the Society for Medicinal Plant Research (Barcelona, Spain) 2002年

所属学協会

Works(作品等)

岐阜県独自の植物資源を利用した健康剤

2000年
Health-Maintaining Agents Using Gifu Prefecture-Original Plant Resources

2000年
食品加工廃棄物の有効利用

1999年
Medicinal Utilization of Garbages Derived from Foodstutt Processing

1999年
神経精神疾患に関与する哺乳類アルカロイド

1998年
Mammalian Alkaloids Responsible for Neuropsychiatric Disorders

1998年

土屋博紀

基本情報

研究キーワード

研究分野

論文

MISC

書籍等出版物

講演・口頭発表等

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

メニュー