KITAGAWA Hiroshi

J-GLOBAL         Last updated: Jun 6, 2018 at 12:45
 
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Name
KITAGAWA Hiroshi
Affiliation
Kyoto University
Section
Graduate School of Science
Job title
Progessor
Degree
(BLANK)(Kyoto University), (BLANK)(Kyoto University)

Research Areas

 
 

Academic & Professional Experience

 
1991
 - 
1994
Research Associate, Institute for Molecular
 
 
   
 
Science
 
1994
 - 
2000
Japan Advanced Institute of Science,
 
 
   
 
Technology
 
2000
   
 
- Department of Chemistry, University of
 

Education

 
 
 - 
1991
Graduate School, Division of Natural Science, Kyoto University
 
 
 - 
1986
Faculty of Science, Kyoto University
 

Published Papers

 
Aoki K, Otsubo K, Hanan GS, Sugimoto K, Kitagawa H
Inorganic chemistry   57(11) 6222-6225   Jun 2018   [Refereed]
Konarev DV, Kuzmin AV, Khasanov SS, Litvinov AL, Otsuka A, Yamochi H, Kitagawa H, Lyubovskaya RN
Chemistry, an Asian journal      May 2018   [Refereed]
Song C, Yang A, Sakata O, Kumara LSR, Hiroi S, Cui YT, Kusada K, Kobayashi H, Kitagawa H
Physical chemistry chemical physics : PCCP      May 2018   [Refereed]
Nadanaka S, Kitagawa H
Biochimica et biophysica acta   1862(4) 791-799   Apr 2018   [Refereed]
Haraguchi Tomoyuki, Otsubo Kazuya, Kitagawa Hiroshi
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (16) 1697-1706   Apr 2018   [Refereed]
Taylor Jared M., Dwyer Patrick J., Reid Joel W., Gelfand Benjamin S., Lim Dae-woon, Donoshita Masaki, Veinberg Stanislav L., Kitagawa Hiroshi, Vukotic V. Nicholas, Shimizu George K. H.
CHEM   4(4) 868-878   Apr 2018   [Refereed]
Matsuki Masaya, Yamada Teppei, Dekura Shun, Kitagawa Hiroshi, Kimizuka Nobuo
CHEMISTRY LETTERS   47(4) 497-499   Apr 2018   [Refereed]
Wang F, Kusada K, Wu D, Yamamoto T, Toriyama T, Matsumura S, Nanba Y, Koyama M, Kitagawa H
Angewandte Chemie (International ed. in English)   57(17) 4505-4509   Apr 2018   [Refereed]
Zhang Quan, Kusada Kohei, Wu Dongshuang, Kawaguchi Shogo, Kubota Yoshiki, Kitagawa Hiroshi
CHEMISTRY LETTERS   47(4) 559-561   Apr 2018   [Refereed]
Yamamoto A, Omotehara T, Miura Y, Takada T, Yoneda N, Hirano T, Mantani Y, Kitagawa H, Yokoyama T, Hoshi N
The Journal of veterinary medical science   80(4) 557-567   Apr 2018   [Refereed]
Yoneda N, Takada T, Hirano T, Yanai S, Yamamoto A, Mantani Y, Yokoyama T, Kitagawa H, Tabuchi Y, Hoshi N
The Journal of veterinary medical science   80(4) 634-637   Apr 2018   [Refereed]
Masuda N, Mantani Y, Yuasa H, Yoshitomi C, Arai M, Nishida M, Qi WM, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   80(3) 395-404   Mar 2018   [Refereed]
Masuda N, Mantani Y, Yoshitomi C, Yuasa H, Nishida M, Arai M, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   80(2) 323-332   Mar 2018   [Refereed]
Takada T, Yoneda N, Hirano T, Yanai S, Yamamoto A, Mantani Y, Yokoyama T, Kitagawa H, Tabuchi Y, Hoshi N
The Journal of veterinary medical science   80(4) 720-724   Apr 2018   [Refereed]
Matsuki Masaya, Yamada Teppei, Yasuda Nobuhiro, Dekura Shun, Kitagawa Hiroshi, Kimizuka Nobuo
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   140(1) 291-297   Jan 2018   [Refereed]
Intra-tumoral 8-OHdG is a novel prognostic factor in advanced colon cancer
Kitagawa Hiroshi, Kitajima Yoshihiko, Nakamura Jun, Tanaka Tomokazu, Koga Yasuo, Manabe Tatsuya, Noshiro Hirokazu
CANCER SCIENCE   109 579   Jan 2018   [Refereed]
Konarev Dmitri V., Khasanov Salavat S., Troyanov Sergey I., Otsuka Akihiro, Yamochi Hideki, Kitagawa Hiroshi, Lyubovskaya Rimma N.
CHEMISTRYSELECT   2(23) 6640-6644   Aug 2017   [Refereed]
Kobayashi H, Kusada K, Kitagawa H
Accounts of chemical research   48(6) 1551-1559   Jun 2015   [Refereed]
Nishida Yoshihide, Sato Katsutoshi, Yamamoto Tomokazu, Wu Dongshuang, Kusada Kohei, Kobayashi Hirokazu, Matsumura Syo, Kitagawa Hiroshi, Nagaoka Katsutoshi
CHEMISTRY LETTERS   46(8) 1254-1257   Aug 2017   [Refereed]
Sakaida Shun, Otsubo Kazuya, Sakata Osami, Song Chulho, Fujiwara Akihiko, Takata Masaki, Kitagawa Hiroshi
NATURE CHEMISTRY   8(4) 377-383   Apr 2016   [Refereed]
Mito-oka Yasuko, Sawada Yuki, Masumori Tadao, Horike Satoshi, Kitagawa Hiroshi, Kitagawa Susumu
CHEMISTRY LETTERS   44(12) 1694-1696   Dec 2015   [Refereed]
Kutubi Md. Shahajahan, Sato Katsutoshi, Wada Kenji, Yamamoto Tomokazu, Matsumura Syo, Kusada Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi, Nagaoka Katsutoshi
CHEMCATCHEM   7(23) 3887-3894   Dec 2015   [Refereed]
Hirano T, Yanai S, Omotehara T, Hashimoto R, Umemura Y, Kubota N, Minami K, Nagahara D, Matsuo E, Aihara Y, Shinohara R, Furuyashiki T, Mantani Y, Yokoyama T, Kitagawa H, Hoshi N
The Journal of veterinary medical science   77(10) 1207-1215   Oct 2015   [Refereed]
Mikami T, Kitagawa H
Glycoconjugate journal   34(6) 725-735   Dec 2017   [Refereed]
Otsubo Kazuya, Kitagawa Hiroshi
APL MATERIALS   2(12)    Dec 2014   [Refereed]
A novel HNK-1 epitope in perineuronal nets
Yabuno Keiko, Izumikawa Tomomi, Takematsu Hiromu, Kitagawa Hiroshi, Oka Shogo
GLYCOBIOLOGY   24(11) 1148-1149   Nov 2014   [Refereed]
Fujie K, Yamada T, Ikeda R, Kitagawa H
Angewandte Chemie (International ed. in English)   53(42) 11302-11305   Oct 2014   [Refereed]
Konarev Dmitri V., Kuzmin Alexey V., Khasanov Salavat S., Batov Mikhail S., Otsuka Akihiro, Yamochi Hideki, Kitagawa Hiroshi, Lyubovskaya Rimma N.
CRYSTENGCOMM   20(4) 385-401   Jan 2018   [Refereed]
Partial Discharge Inception Voltage Measurements of Ester Dielectric Fluid for Insulation Diagnosis
2017 6TH INTERNATIONAL YOUTH CONFERENCE ON ENERGY (IYCE)      2017   [Refereed]
Mitsuka Yuko, Nagashima Kazuro, Kobayashi Hirokazu, Kitagawa Hiroshi
CHEMISTRY LETTERS   45(11) 1313-1315   Nov 2016   [Refereed]
Dietzel Pascal D. C., Kitagawa Hiroshi
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (27) 4273-4274   Sep 2016   [Refereed]
Bao Song-Song, Li Nan-Zhu, Taylor Jared M., Shen Yang, Kitagawa Hiroshi, Zheng Li-Min
CHEMISTRY OF MATERIALS   27(23) 8116-8125   Dec 2015   [Refereed]
Fujie Kazuyuki, Ikeda Ryuichi, Otsubo Kazuya, Yamada Teppei, Kitagawa Hiroshi
CHEMISTRY OF MATERIALS   27(21) 7355-7361   Nov 2015   [Refereed]
Hirano T, Kobayashi Y, Omotehara T, Tatsumi A, Hashimoto R, Umemura Y, Nagahara D, Mantani Y, Yokoyama T, Kitagawa H, Hoshi N
The Journal of veterinary medical science   76(9) 1201-1208   Sep 2014   [Refereed]
Sadakiyo Masaaki, Yamada Teppei, Kitagawa Hiroshi
CHEMPLUSCHEM   81(8) 691-701   Aug 2016   [Refereed]
Yutsudo N, Kitagawa H
Experimental neurology   274(Pt B) 126-133   Dec 2015   [Refereed]
Deficient mieap expression increases invasion ability via impairment of MQC in gastric cancer cells under hypoxia
Okuyama Keiichiro, Kitajima Yoshihiko, Tanaka Tomokazu, Nakamura Jun, Kitagawa Hiroshi, Egawa Noriyuki, Yanagihara Kazuyoshi, Nakamura Yasuyuki, Arakawa Hirofumi, Noshiro Hirokazu
CANCER SCIENCE   109 874   Jan 2018   [Refereed]
Konarev Dmitri V., Kuzmin Alexey V., Khasanov Salavat S., Troyanov Sergey I., Otsuka Akihiro, Yamochi Hideki, Kitagawa Hiroshi, Lyubovskaya Rimma N.
ORGANOMETALLICS   36(20) 4032-4037   Oct 2017   [Refereed]
Miyata S, Kitagawa H
Biochimica et biophysica acta   1861(10) 2420-2434   Oct 2017   [Refereed]
Mieap expression is associated with MQC integrity and controls ROS production in gastric cancer cells under hypoxia
Kitajima Yoshihiko, Okuyama Keiichiro, Tanaka Tomokazu, Nakamura Jun, Kitagawa Hiroshi, Egawa Noriyuki, Yanagihara Kazuyoshi, Nakamura Yasuyuki, Arakawa Hirofumi, Noshiro Hirokazu
CANCER SCIENCE   109 909   Jan 2018   [Refereed]
Seo Okkyun, Sakata Osami, Kim Jae Myung, Hiroi Satoshi, Song Chulho, Kumara Loku Singgappulige Rosantha, Ohara Koji, Dekura Shun, Kusada Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi
APPLIED PHYSICS LETTERS   111(25)    Dec 2017   [Refereed]
Dekura Shun, Kobayashi Hirokazu, Li Guangqin, Ikeda Ryuichi, Kubota Yoshiki, Takata Masaki, Kitagawa Hiroshi
CHEMISTRY LETTERS   43(8) 1363-1364   Aug 2014   [Refereed]
Li Guangqin, Kobayashi Hirokazu, Taylor Jared M., Ikeda Ryuichi, Kubota Yoshiki, Kato Kenichi, Takata Masaki, Yamamoto Tomokazu, Toh Shoichi, Matsumura Syo, Kitagawa Hiroshi
NATURE MATERIALS   13(8) 802-806   Aug 2014   [Refereed]
Bao SS, Otsubo K, Taylor JM, Jiang Z, Zheng LM, Kitagawa H
Journal of the American Chemical Society   136(26) 9292-9295   Jul 2014   [Refereed]
Takeda Norihiko, Ueda Masafumi, Mori Nagisa, Miyoshi Tetsuya, Shimoda Manami, Uno Yumina, Kitagawa Hiroshi, Emoto Noriaki, Mukai Takahiro, Miyata Okiko
HETEROCYCLES   94(4) 750-+   Apr 2017   [Refereed]
Omotehara Takuya, Minami Kiichi, Mantani Youhei, Umemura Yuria, Nishida Miho, Hirano Tetsushi, Yoshioka Hidefumi, Kitagawa Hiroshi, Yokoyama Toshifumi, Hoshi Nobuhiko
DEVELOPMENTAL DYNAMICS   246(2) 148-156   Feb 2017   [Refereed]
Isfahani Ali Pournaghshband, Ghalei Behnam, Bagheri Rouhollah, Kinoshita Yosuke, Kitagawa Hiroshi, Sivaniah Easan, Sadeghi Morteza
JOURNAL OF MEMBRANE SCIENCE   513 58-66   Sep 2016   [Refereed]
Kawaguchi Genta, Maesato Mitsuhiko, Komatsu Tokutaro, Imakubo Tatsuro, Kitagawa Hiroshi
PHYSICAL REVIEW B   93(7)    Feb 2016   [Refereed]
Yamada Teppei, Sadakiyo Masaaki, Shigematsu Akihito, Kitagawa Hiroshi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN   89(1) 1-10   Jan 2016   [Refereed]
Mantani Youhei, Ito Eri, Nishida Miho, Yuasa Hideto, Masuda Natsumi, Qi Wang-Mei, Kawano Junichi, Yokoyama Toshifumi, Hoshi Nobuhiko, Kitagawa Hiroshi
JOURNAL OF VETERINARY MEDICAL SCIENCE   77(9) 1121-1128   Sep 2015   [Refereed]
Akiba Hiroshi, Kobayashi Hirokazu, Kitagawa Hiroshi, Kofu Maiko, Yamamuro Osamu
PHYSICAL REVIEW B   92(6)    Aug 2015   [Refereed]
Tanaka Ryoji, Yokoyama Tetsuya, Kitagawa Hiroshi, Tesfaye Demissie Bizuneh, Nakamura Eizo
CHEMICAL GEOLOGY   396 255-264   Mar 2015   [Refereed]
Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H
Scientific reports   5 8994   Mar 2015   [Refereed]
Roesler Christoph, Esken Daniel, Wiktor Christian, Kobayashi Hirokazu, Yamamoto Tomokazu, Matsumura Syo, Kitagawa Hiroshi, Fischer Roland A.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (32) 5514-5521   Nov 2014   [Refereed]
Izumikawa T, Sato B, Mikami T, Tamura J, Igarashi M, Kitagawa H
The Journal of biological chemistry   290(9) 5438-5448   Feb 2015   [Refereed]
Takahara E, Yuasa H, Nishida M, Mantani Y, Udayanga KG, Qi WM, Takeuchi T, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   77(4) 387-393   Apr 2015   [Refereed]
Ōkawa H, Sadakiyo M, Otsubo K, Yoneda K, Yamada T, Ohba M, Kitagawa H
Inorganic chemistry   54(17) 8529-8535   Sep 2015   [Refereed]
Heparan Sulfate Containing Unsubstituted Glucosamine Residues: Biosynthesis and Heparanase Inhibitory Activity
Nadanaka Satomi, Purunomo Eko, Takeda Naoko, Tamura Jun-ichi, Kitagawa Hiroshi
GLYCOBIOLOGY   24(11) 1206   Nov 2014   [Refereed]
Yang Anli, Sakata Osami, Kusada Kohei, Yayama Tomoe, Yoshikawa Hideki, Ishimoto Takayoshi, Koyama Michihisa, Kobayashi Hirokazu, Kitagawa Hiroshi
APPLIED PHYSICS LETTERS   105(15)    Oct 2014   [Refereed]
Sadakiyo M, Yamada T, Kitagawa H
Journal of the American Chemical Society   136(38) 13166-13169   Sep 2014   [Refereed]
Tadokoro M, Ohhata Y, Shimazaki Y, Ishimaru S, Yamada T, Nagao Y, Sugaya T, Isoda K, Suzuki Y, Kitagawa H, Matsui H
Chemistry (Weinheim an der Bergstrasse, Germany)   20(42) 13698-13709   Oct 2014   [Refereed]
Yamamoto T, Kobayashi H, Kumara LSR, Sakata O, Nitta K, Uruga T, Kitagawa H
Nano letters   17(9) 5273-5276   Sep 2017   [Refereed]
Otsubo Kazuya, Haraguchi Tomoyuki, Kitagawa Hiroshi
COORDINATION CHEMISTRY REVIEWS   346 123-138   Sep 2017   [Refereed]
Kofu Maiko, Hashimoto Naoki, Akiba Hiroshi, Kobayashi Hirokazu, Kitagawa Hiroshi, Iida Kazuki, Nakamura Mitsutaka, Yamamuro Osamu
PHYSICAL REVIEW B   96(5)    Aug 2017   [Refereed]
Kawaguchi Genta, Maesato Mitsuhiko, Komatsu Tokutaro, Imakubo Tatsuro, Kiswandh Andhika, Graf David, Kitagawa Hiroshi
CHEMISTRY OF MATERIALS   28(20) 7276-7286   Oct 2016   [Refereed]
Otsubo Kazuya, Suto Tomohiko, Kobayashi Atsushi, Ikeda Ryuichi, Hedo Masato, Uwatoko Yoshiya, Kitagawa Hiroshi
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (27) 4402-4407   Sep 2016   [Refereed]
Kofu Maiko, Hashimoto Naoki, Akiba Hiroshi, Kobayashi Hirokazu, Kitagawa Hiroshi, Tyagi Madhusudan, Faraone Antonio, Copley John R. D., Lohstroh Wiebke, Yamamuro Osamu
PHYSICAL REVIEW B   94(6)    Aug 2016   [Refereed]
Fujie Kazuyuki, Kitagawa Hiroshi
COORDINATION CHEMISTRY REVIEWS   307 382-390   Jan 2016   [Refereed]
Umemura Y, Miyamoto R, Hashimoto R, Kinoshita K, Omotehara T, Nagahara D, Hirano T, Kubota N, Minami K, Yanai S, Masuda N, Yuasa H, Mantani Y, Matsuo E, Yokoyama T, Kitagawa H, Hoshi N
The Journal of veterinary medical science   77(12) 1587-1598   Jan 2016   [Refereed]
Sadakiyo Masaaki, Yamada Teppei, Kitagawa Hiroshi
INORGANIC CHEMISTRY COMMUNICATIONS   72 138-140   Oct 2016   [Refereed]
Kobayashi K, Kobayashi H, Maesato M, Hayashi M, Yamamoto T, Yoshioka S, Matsumura S, Sugiyama T, Kawaguchi S, Kubota Y, Nakanishi H, Kitagawa H
Angewandte Chemie (International ed. in English)   56(23) 6578-6582   Jun 2017   [Refereed]
Sadakiyo Masaaki, Yamada Teppei, Kato Kenichi, Takata Masaki, Kitagawa Hiroshi
CHEMICAL SCIENCE   7(2) 1349-1356   2016   [Refereed]
Sakaida S, Haraguchi T, Otsubo K, Sakata O, Fujiwara A, Kitagawa H
Inorganic chemistry   56(14) 7606-7609   Jul 2017   [Refereed]
Kumara L. S. R., Sakata Osami, Kohara Shinji, Yang Anli, Song Chulho, Kusada Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi
PROCEEDINGS OF THE 12TH INTERNATIONAL CONFERENCE ON SYNCHROTRON RADIATION INSTRUMENTATION (SRI2015)   1741    2016   [Refereed]
Taniguchi M, Nadanaka S, Tanakura S, Sawaguchi S, Midori S, Kawai Y, Yamaguchi S, Shimada Y, Nakamura Y, Matsumura Y, Fujita N, Araki N, Yamamoto M, Oku M, Wakabayashi S, Kitagawa H, Yoshida H
Cell structure and function   40(1) 13-30   2015   [Refereed]
Pineda-Velasco Ivan, Nguyen Tai T., Kitagawa Hiroshi, Nakamura Eizo
GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS   16(9) 2848-2852   Sep 2015   [Refereed]
Taylor Jared M., Dekura Shun, Ikeda Ryuichi, Kitagawa Hiroshi
CHEMISTRY OF MATERIALS   27(7) 2286-2289   Apr 2015   [Refereed]
Element strategy for new nanomaterials
Kitagawa Hiroshi
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   249    Mar 2015   [Refereed]
Watanabe Y, Haraguchi T, Otsubo K, Sakata O, Fujiwara A, Kitagawa H
Chemical communications (Cambridge, England)   53(73) 10112-10115   Sep 2017   [Refereed]
Krishnan Karthik, Yamada Tomoaki, Iwatsuki Hiroko, Hara Mitsuo, Nagano Shusaku, Otsubo Kazuya, Sakata Osami, Fujiwara Akihiko, Kitagawa Hiroshi, Nagao Yuki
ELECTROCHEMISTRY   82(10) 865-869   Oct 2014   [Refereed]
Huang Bo, Kobayashi Hirokazu, Kitagawa Hiroshi
CHEMISTRY LETTERS   43(9) 1459-1460   Sep 2014   [Refereed]
Takaishi S, Kitagawa H, Tanaka H, Kuroda S, Ikeda R
Dalton transactions (Cambridge, England : 2003)   43(30) 11529-11532   Aug 2014   [Refereed]
Miyata S, Kitagawa H
Journal of biochemistry   157(1) 13-22   Jan 2015   [Refereed]
Mantani Y, Yuasa H, Nishida M, Takahara E, Omotehara T, Udayanga KG, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   76(6) 833-838   Jun 2014   [Refereed]
Mantani Y, Ito E, Nishida M, Yuasa H, Masuda N, Qi WM, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   77(9) 1121-1128   Sep 2015   [Refereed]
Schiavi Federica, Rosciglione Alberto, Kitagawa Hiroshi, Kobayashi Katsura, Nakamura Eizo, Nuccio Pasquale Mario, Ottolini Luisa, Paonita Antonio, Vannucci Riccardo
GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS   16(7) 2109-2126   Jul 2015   [Refereed]
Matsushita K, Nakata T, Takeda-Okuda N, Nadanaka S, Kitagawa H, Tamura JI
Bioorganic & medicinal chemistry   26(5) 1016-1025   Mar 2018   [Refereed]
Kinouchi H, Arimoto H, Nishiguchi K, Oka M, Maki H, Kitagawa H, Kamimori H
Analytical biochemistry   452 67-75   May 2014   [Refereed]
Uchida Sayaka, Ogasawara Yoshiyuki, Maruichi Toshiaki, Kumamoto Akihito, Ikuhara Yuichi, Yamada Teppei, Kitagawa Hiroshi, Mizuno Noritaka
CRYSTAL GROWTH & DESIGN   14(12) 6620-6626   Dec 2014   [Refereed]
Hashiguchi R, Otsubo K, Maesato M, Sugimoto K, Fujiwara A, Kitagawa H
Angewandte Chemie (International ed. in English)   56(14) 3838-3841   Mar 2017   [Refereed]
Inagaki Yuji, Sakamoto Yasutaka, Morodomi Hiroki, Kawae Tatsuya, Yoshida Yasuo, Asano Takayuki, Hosoi Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi, Ajiro Yoshitami, Furukawa Yuji
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN   83(5)    May 2014   [Refereed]
Konarev DV, Kuzmin AV, Khasanov SS, Shestakov AF, Yudanova EI, Otsuka A, Yamochi H, Kitagawa H, Lyubovskaya RN
The Journal of organic chemistry   83(4) 1861-1866   Feb 2018   [Refereed]
Miyamoto K, Tanaka N, Moriguchi K, Ueno R, Kadomatsu K, Kitagawa H, Kusunoki S
Glycobiology   24(5) 469-475   May 2014   [Refereed]
Highly sulfated chondroitin sulfate chains regulate neuronal polarity formation
Mikami Tadahisa, Shida Miharu, Kitagawa Hiroshi
GLYCOBIOLOGY   24(11) 1153-1154   Nov 2014   [Refereed]
Yamada T, Shirai Y, Kitagawa H
Chemistry, an Asian journal   9(5) 1316-1320   May 2014   [Refereed]
Regulatory mechanism of chondroitin sulfate-mediated axon guidance
Nakamura Masao, Tamura Jun-ichi, Kitagawa Hiroshi, Tojima Takuro, Kamiguchi Hiroyuki
GLYCOBIOLOGY   24(11) 1158   Nov 2014   [Refereed]
Kawaguchi G, Maesato M, Komatsu T, Kitagawa H, Imakubo T, Kiswandhi A, Graf D, Brooks JS
Angewandte Chemie (International ed. in English)   54(35) 10169-10172   Aug 2015   [Refereed]
Huang B, Kobayashi H, Yamamoto T, Matsumura S, Nishida Y, Sato K, Nagaoka K, Kawaguchi S, Kubota Y, Kitagawa H
Journal of the American Chemical Society   139(13) 4643-4646   Apr 2017   [Refereed]
Yamamoto Takayuki, Kobayashi Hirokazu, Kitagawa Hiroshi
CHEMISTRY LETTERS   43(8) 1355-1356   Aug 2014   [Refereed]

Misc

 
K. G.S. Udayanga, H. Miyata, Y. Yokoo, W. M. Qi, E. Takahara, Y. Mantani, T. Yokoyama, N. Hoshi, H. Kitagawa
Histology and Histopathology   26 811-820   Jul 2011
Epidermal homeostasis is maintained by both epithelial proliferation in the stratum basale (SB) and the apoptosis of epithelial cells under physiological conditions. In this study, the induction and regulation mechanisms of epidermal apoptosis wer...
A. Sano, H. Kage, K. Sugimoto, H. Kitagawa, N. Aki, A. Goto, M. Fukayama, J. Nakajima, S. Takamoto, T. Nagase, Y. Yatomi, N. Ohishi, D. Takai, D. Takai
Oncogene   26 6518-6525   Oct 2007
Cancer-specific gene promoter methylation has been described in many types of cancers, and various semi-quantified results have shown their usefulness. Here, we show a more sensitive and specific second-generation system for profiling the DNA meth...
Shuji Mizumoto, Hiroshi Kitagawa, Kazuyuki Sugahara
Chemistry and Biology of Heparin and Heparan Sulfate   203-243   Dec 2005
This chapter focuses on recent advances in the study of the biosynthesis and the functions of heparin (HP) and heparan sulfate (HS). They are structurally the most complex species of the glycosaminoglycan (GAG) family. During the synthesis of the ...
Hiroshi Kitagawa, Hiroshi Kitagawa, Akiteru Goto, Manabu Minami, Jun Nakajima, Toshiro Niki, Masashi Fukayama
Japanese Journal of Clinical Oncology   33 541   Oct 2003
J. H. Lee, S. K. Ku, Hyeung Sik Lee, H. Kitagawa
European Journal of Histochemistry   47 165-172   Jun 2003
The regional distribution and frequency of pancreatic endocrine cells in the red-bellied frog, Bombina orientalis, were studied by the immunohistochemical peroxidase antiperoxidase (PAP) method using five types of specific mammalian antisera to in...
Byung Taek Kim, Hiroshi Kitagawa, Kazuyuki Sugahara
Connective Tissue   34 261-265   Sep 2002
Hereditary multiple exostoses, (HME) are benign bone tumors genetically associated with mutations in either EXT1 or EXT2, both of which have tumor suppressor functions. Subsequent cloning of three EXT-like genes, EXTL1, EXTL2 and EXTL3, has reveal...
K. Sugahara, S. Yamada, H. Kitagawa
Seikagaku   73 458-470   Dec 2001
Hiroshi Kitagawa, Toru Uyama, Kazuyuki Sugahara
Journal of Biological Chemistry   276 38721-38726   Oct 2001
We have identified a human chondroitin synthase from the HUGE (human unidentified gene-encoded large proteins) protein data base by screening with two keywords: "one transmembrane domain" and " galactosyltransferase family." The identified protein...
H. Kitagawa, M. Taoka, Y. Tone, K. Sugahara
Biochemical Journal   358 539-546   Sep 2001
Here we describe the characterization of the human glycosaminoglycan glucuronyltransferase I gene (GlcAT-I) and a related pseudogene. The GlcAT-I gene was localized to human chromosome 11q12-q13 by in situ hybridization of metaphase chromosomes. G...
Byung Taek Kim, Hiroshi Kitagawa, Jun Ichi Tamura, Toshiyuki Saito, Marion Kusche-Gullberg, Ulf Lindahl, Kazuyuki Sugahara, Kazuyuki Sugahara
Proceedings of the National Academy of Sciences of the United States of America   98 7176-7181   Jun 2001
The tumor suppressors EXT1 and EXT2 are associated with hereditary multiple exostoses and encode bifunctional glycosyltransferases essential for chain polymerization of heparan sulfate (HS) and its analog, heparin (Hep). Three highly homologous EX...
Jun Ichi Tamura, Hirofumi Urashima, Kazunori Tsuchida, Hiroshi Kitagawa, Kazuyuki Sugahara
Carbohydrate Research   332 41-51   May 2001
Newly designed linear-type glycoclusters were synthesized which involve a chondroitin repeating disaccharide ligand and a hydrophobic octyl ether spacer. The spacer mimics the corresponding disaccharide unit. Repeating elongation of the pseudo-tet...
Hiroshi Kitagawa, Noriyuki Egusa, Jun Ichi Tamura, Marion Kusche-Gullberg, Ulf Lindahl, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   276 4834-4838   Feb 2001
The proteins encoded by the EXT1, EXT2, and EXTL2 genes, members of the hereditary multiple exostoses gene family of tumor suppressors, are glycosyltransferases required for the heparan sulfate biosynthesis. Only two homologous genes, rib-1 and ri...
T. Murakawa, J. Nakajima, M. Tanaka, S. Takamoto, H. Kitagawa, M. Fukayama
Kyobu geka. The Japanese journal of thoracic surgery   54 829-834   Jan 2001
A 78-year-old asymptomatic woman was referred to our department for the treatment of a right lung tumor. The patient had been suffering from rheumatoid arthritis and followed up in outpatient clinic. On March 6, 1995, abnormal shadow in the right ...
R. Makiura, I. Nagasawa, N. Kimura, S. Ishimaru, H. Kitagawa, R. Ikeda,
Chem. Commun.   17 1642-1643   2001
M. Mitsumi, T. Murase, H. Kishida, T. Yoshinari, Y. Ozawa, K. Toriumi, T. Sonoyama,H. Kitagawa, T. Mitani,
J. Am. Chem. Soc.   123 11179-11192   2001
Hiroshi Kitagawa, Hiroshi Kitagawa, Shigekazu Shiraishi, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   197 607-616   Dec 2000
To clarify the nature of M cells, the detailed ultrastructural characteristics and lectin-binding properties of M cells were investigated in follicle-associated epithelium (FAE) of chicken caecal tonsils. M cells presented various outlines from co...
Lars C. Pedersen, Kazunori Tsuchida, Hiroshi Kitagawa, Kazuyuki Sugahara, Thomas A. Darden, Masahiko Negishi
Journal of Biological Chemistry   275 34580-34585   Nov 2000
Human β1,3-glucuronyltransferase I (GlcAT-I) is a central enzyme in the initial steps of proteoglycan synthesis. GlcAT-I transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisa...
Hiromi Sakaguchi, Hiroshi Kitagawa, Kazuyuki Sugahara
Biochimica et Biophysica Acta - General Subjects   1523 269-276   Oct 2000
The cDNA and gene encoding human N-acetylglucosamine-6-O-sulfotransferase (Gn6ST) have been cloned. Comparative analysis of this cDNA with the mouse Gn6ST sequence indicates 96% amino acid identity between the two sequences. The expression of a so...
Masakatsu Yamamoto, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara, Masato Uehara
Brain Research Bulletin   52 537-546   Aug 2000
The organization of spinocerebellar tract (SCT) neurons in the chicken was studied quantitatively using retrograde wheat germ agglutinin-horseradish peroxidase labelling. The chicken spinal cord was divided into five regions based on the distribut...
Hiroshi Kitagawa, Masaki Fujita, Nobue Ito, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   275 21075-21080   Jul 2000
A novel human chondroitin 6-O-sulfotransferase, designated C6ST-2, was identified by BLAST analysis of expressed sequence tag using the sequence of a previously described human chondroitin 6-O-sultotransferase (C6ST-1) as a probe. The new cDNA seq...
Masato Uehara, Masato Uehara, Kazuhiko Taguchi, Tomohiro Imagawa, Hiroshi Kitagawa
Journal of Morphology   244 15-22   Apr 2000
The spinal cords of vertebrates are generally divided into the cord proper and the minute filum terminale. While the spinal cord extends the entire length of the vertebral canal in the adult tiger puffer, Takifugu rubripes, the cord proper is grea...
Kazuyuki Sugahara, Hiroshi Kitagawa
Current Opinion in Structural Biology   10 518-527   Jan 2000
Recent cDNA cloning of the glycosyltransferases involved in the synthesis of the sulfated glycosaminoglycan sidechains of proteoglycans has provided important clues to answering long-standing questions concerning the mechanisms of both chain polym...
Claire Senay, Thomas Lind, Kumi Muguruma, Yuko Tone, Hiroshi Kitagawa, Kazuyuki Sugahara, Kerstin Lidholt, Ulf Lindahl, Marion Kusche-Gullberg
EMBO Reports   1 282-286   Jan 2000
The D-glucuronyltransferase and N-acetyl-D-glucosaminyl-transferase reactions in heparan sulfate biosynthesis have been associated with two genes, EXT1 and EXT2, which are also implicated in the inherited bone disorder, multiple exostoses. Since t...
H. Kitagawa, K. Sugahara
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   45 579-586   Jan 2000
Etsumori Harada, Yoshinori Itoh, Kiitiro Sitizyo, Takashi Takeuchi, Yumi Araki, Hiroshi Kitagawa
Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology   124 321-327   Nov 1999
Lactoferrin is a major iron-binding protein in milk from several species, such as humans, monkeys, mice and sows. Using neonatal and weaner piglets, the characteristic transfer of lactoferrin from intestinal lumen into bile via the circulation was...
Shuhei Yamada, Irma Van Die, Dirk H. Van Den Eijnden, Akiko Yokota, Hiroshi Kitagawa, Kazuyuki Sugahara
FEBS Letters   459 327-331   Oct 1999
A considerable amount (approximately 1.6 μg from 1 mg of dried nematode) of non-sulfated chondroitin, two orders of magnitude less yet an appreciable amount of heparan sulfate, and no hyaluronate were found in Caenorhabditis elegans nematodes. The...
Yuko Tone, Hiroshi Kitagawa, Kimiyuki Imiya, Shogo Oka, Toshisuke Kawasaki, Kazuyuki Sugahara
FEBS Letters   459 415-420   Oct 1999
We characterized the recombinant glucuronyltransferase I (GlcAT-I) involved in the glycosaminoglycan-protein linkage region biosynthesis. The enzyme showed strict specificity for Galβ1-3Galβ1-4Xyl, exhibiting negligible incorporation into other ga...
Kazunori Tsuchida, Thomas Lind, Hiroshi Kitagawa, Ulf Lindahl, Kazuyuki Sugahara, Kazuyuki Sugahara, Kerstin Lidholt
European Journal of Biochemistry   264 461-467   Sep 1999
β-N-Acetylgalactosaminyltransferase II and β-glucuronyltransferase II, involved in chondroitin sulfate biosynthesis, transfer an N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) residue, respectively, through β-linkages to an acceptor ch...
Tomohiro Imagawa, Yuko Fujita, Hiroshi Kitagawa, Masato Uehara
Journal of Veterinary Medical Science   61 883-889   Aug 1999
The optic nerve fiber layer (NFL) of the chicken retina was studied quantitatively and morphologically at 17 positions along seven radially arranged bands from the dorsal tip of the pecten oculi using electron microscopy. The number of nerve fiber...
Hiroshi Kitagawa, Yuko Kano, Hiromi Shimakawa, Fumitaka Goto, Fumitaka Goto, Tomoya Ogawa, Tomoya Ogawa, Hidetoshi Okabe, Kazuyuki Sugahara
Glycobiology   9 697-703   Jul 1999
We recently discovered a novel α-N-acetylgalactosaminyl-transferase in fetal bovine serum and also in mouse mastcytoma cells, which catalyzed the transfer of an α-GalNAc residue to the linkage tetrasaccharide-serine, GlcAβ1-3Galβ1-3Galβ1-4Xylβ1-O-...
Satomi Nadanaka, Hiroshi Kitagawa, Fumitaka Goto, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Kazuyuki Sugahara
Biochemical Journal   340 353-357   Jun 1999
α-Thrombomodulin (α-TM) with a truncated glycosaminoglycan-protein linkage tetrasaccharide, GlcAβ1-3Galβ1-3Galβ1-4Xyl, was tested as an acceptor together with a sugar donor, UDP-N-[ 3 H]acetylgalactosamine, using a cell-free enzyme system prepared...
Hiroshi Kitagawa, Hiromi Shimakawa, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   274 13933-13937   May 1999
We previously demonstrated a unique α-N- acetylgalactosaminyltransferase that transferred N-acetylgalactosamine (GalNAc) to the tetrasaccharide-serine, GlcAβ1-3Galβ1-3Galβ1-4Xylβ1-O- Ser (GlcA represents glucuronic acid), derived from the common g...
Yuko Mizushima, Yuko Mizushima, Yukio Amano, Hiroshi Kitagawa, Kenji Ogata
Journal of Pharmacology and Experimental Therapeutics   288 849-857   Feb 1999
Leflunomide, a drug being developed for use in the treatment of rheumatoid arthritis, was evaluated in an ovalbumin (OVA)induced rat type 1 allergy model. In a dose of 1 mg/kg/day, it strongly suppressed the formation of OVA-specific IgE, thus pre...
Takashi Takeuchi, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara
Journal of Veterinary Medical Science   61 149-154   Feb 1999
The process of the disappearance of epithelial cells was examined in chicken cecal villi and follicle-associated epithelium (FAE). The apoptotic epithelial cells with intense DNA-fragmentation and their exfoliation were found in the villous tips. ...
Osamu Ishihara, Osamu Ishihara, Masahiro Saitoh, Katsuyuki Kinoshita, Hitoshi Takanashi, Yoshinori Arai, Hiroshi Kitagawa
Acta Obstetricia et Gynecologica Scandinavica   78 321-325   Jan 1999
Background. To investigate the role of interleukin-1 related substances in amniotic fluid in normal term labor without intrauterine infection. Methods. Amniotic fluid samples were collected from forty-one patients with various backgrounds. A novel...
Y. Arai, H. Takanashi, H. Kitagawa, K. J. Wirth, I. Okayasu
Digestive Diseases and Sciences   44 845-851   Jan 1999
Dextran sulfate sodium-induced colitis in mice has been recognized as a model for human ulcerative colitis. Using this model, we carried out a study on the preventive effect of Icatibant, a bradykinin B 2 receptor antagonist previously called HOE ...
Kae Tsutsumi, Hiromi Shimakawa, Hiroshi Kitagawa, Kazuyuki Sugahara
FEBS Letters   441 235-241   Dec 1998
The cDNA and gene encoding human chondroitin 6-sulfotransferase (C6ST) have been cloned. The expression of a soluble recombinant form of the protein in COS-1 cells produced an active sulfotransferase, which used as acceptor substrates polymer chon...
Satomi Nadanaka, Hiroshi Kitagawa, Kazuyuki Sugahara
Journal of Biological Chemistry   273 33728-33734   Dec 1998
Thrombomodulin (TM), a cell surface glycoprotein, is a critical mediator of endothelial anticoagulant defenses occurring both as a chondroitin sulfate proteoglycan (β-TM) and a protein (α-TM) unsubstituted by chondroitin sulfate (CS), hence its de...
Tetsuro Matsuura, Isao Narama, Kiyokazu Ozaki, Masahiko Nishimura, Tomohiro Imagawa, Hiroshi Kitagawa, Masato Uehara
Anatomy and Embryology   198 91-99   Sep 1998
The knotty-tail (knt/knt) mouse has a short and knotty tail. The tail deformity is caused by a decrease in the number of caudal vertebrae and a deformity of them in the distal parr of the tail. The objective of the study was to determine how reduc...
Takashi Takeuchi, Hiroshi Kitagawa, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   193 233-239   Aug 1998
The proliferation sites and cellular kinetics of villous epithelial cells and M cells in the intestine of the adult chicken have never been clarified. In this study, we determined the proliferation sites in the chicken caecum using colchicine trea...
Hiroshi Kitagawa, Yuko Tone, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Shogo Oka, Toshisuke Kawasaki, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   273 6615-6618   Mar 1998
We isolated a cDNA encoding a novel glucuronyltransferase from human placenta cDNA with the use of the degenerate reverse transcriptase-polymerase chain reaction method. Degenerate primers ware designed based upon the amino acid sequence alignment...
Tetsuro Matsuura, Isao Narama, Kiyokazu Ozaki, Hiroo Nakajima, Masahiko Nishimura, Tomohiro Imagawaj, Hiroshi Kitagawa, Masato Uehara
Congenital Anomalies   38 67-79   Mar 1998
Mice with short and knotty tails arose as a spontaneous mutant in an ICR strain, and they have been named knotty-tail mouse (gene symbol; knt). They also have a minor anomaly of the cervical vertebrae, especially in the axis. In this study, the ce...
Masato Uehara, Tomohiro Imagawa, Hiroshi Kitagawa
Journal of Veterinary Medical Science   60 773-775   Jan 1998
The present study was designed to reveal whether astrocytic activation following axotomy causes a numerical increase of nuclear bodies (NBs) in chicken astrocytes. Astrocytes in the spinal cord were activated by a unilateral spinal nerve transecti...
Hiroshi Kitagawa, Hiroshi Kitagawa, Yoshitoshi Hiratsuka, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   192 293-298   Jan 1998
In order to clarify the fundamental structure of the host defence mechanism in chicken caeca, a detailed analysis of the distribution of lymphoid nodules (LNs) was carried out on longitudinal sections of both the mesenteric (side of the ileocaecal...
Yoshinori Arai, Yoshinori Arai, Hitoshi Takanashi, Hiroshi Kitagawa, Isao Okayasu
Cytokine   10 890-896   Jan 1998
Dextran sulfate sodium (DSS)-induced colitis in mice has been recognized as a model for human ulcerative colitis. Using this model, the effects of anti-murine interleukin 1β (IL-1β) antibodies (anti-muIL-1β) and recombinant murine IL-1 receptor ty...
K. Tsuchida, H. Kitagawa, K. Sugahara
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   43 2594-2601   Jan 1998
Hiroshi Kitagawa, Kae Tsutsumi, Yuko Tone, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   272 31377-31381   Dec 1997
Developmentally regulated and cell type-specific expression of distinct sulfated glycosaminoglycan structures on cell surface proteoglycans is increasingly recognized as providing information relevant to cell-cell interactions and differentiation ...
Osamu Ishihara, Hitomi Numari, Masahiro Saitoh, Yoshinori Arai, Hitoshi Takanashi, Hiroshi Kitagawa, Katsuyuki Kinoshita
Advances in Experimental Medicine and Biology   433 419-422   Dec 1997
H. Kitagawa, K. Sugahara
Connective Tissue   29 267-272   Dec 1997
The diverse functions ascribed to chondroitin sulfate (CS) and characteristic CS chains are expressed in a tissue- and cell type-specific manner, suggesting that the sulfation and polymerization of the CS chains are strictly regulated. Nevertheles...
Hiroshi Kitagawa, Mika Oyama, Kimiko Masayama, Yu Yamaguchi, Kazuyuki Sugahara, Kazuyuki Sugahara
Glycobiology   7 1175-1180   Dec 1997
Decorin is a small fibroblast proteoglycan consisting of a core protein and a single chondroitin/dermatan sulfate chain. The structure of the carbohydrate-protein linkage region of the recombinant decorin expressed in Chinese hamster ovary cells w...
Kerstin Lidholt, Maria Fjelstad, Ulf Lindahl, Fumitaka Goto, Tomoya Ogawa, Hiroshi Kitagawa, Kazuyuki Sugahara
Glycoconjugate Journal   14 737-742   Oct 1997
Two glycosaminoglycan-protein linkage tetrasaccharide-serine compounds, GlcAβ1-3Galβ1-3Galβ1-4Xylβ1-O-Ser and GlcAβ1-3Gal(4-O-sulfate)β1-3Galβ1-4Xylβ1-O-Ser, were tested as hexosamine accepters, using UDP-[ 3 H]GlcNAc and UDP-[ 3 H]GalNAc as sugar...
Hiroshi Kitagawa, Miho Ujikawa, Kae Tsutsumi, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Kazuyuki Sugahara, Kazuyuki Sugahara
Glycobiology   7 905-911   Oct 1997
We studied a glucuronyltransferase involved in chondroitin sulfate (CS) biosynthesis in a preparation obtained from fetal bovine serum by heparin-Sepharose affinity chromatography. This enzyme transferred GlcA from UDP-GlcA to the nonreducing GalN...
Hiroshi Kitagawa, Kae Tsutsumi, Miho Ujikawa, Fumitaka Goto, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Kazuyuki Sugahara
Glycobiology   7 531-537   Jun 1997
The relationship between sulfation and polymerization in chondroitin sulfate (CS) biosynthesis has been poorly understood. In this study, we investigated the specificity of bovine serum UDP-GalNAc: CS β-GalNAc transferase responsible for chain elo...
Hiroshi Kitagawa, Yukako Tanaka, Shuhei Yamada, Nobuko Seno, Stuart M. Haslam, Howard R. Morris, Anne Dell, Kazuyuki Sugahara
Biochemistry   36 3998-4008   Apr 1997
Novel sulfated tetrasaccharide structures containing 3-O-sulfated GlcA were isolated recently from king crab cartilage chondroitin sulfate K [Sugahara, K., Tanaka, Y., Yamada, S., Seno, N., Kitagawa, H., Haslam, S. M., Morris, H. R., and Dell, A. ...
Takahiro Kanno, Namiko Koyanagi, Youli Katoku, Akie Yonekubo, Takaji Yajima, Takaji Yajima, Tamotsu Kuwata, Hiroshi Kitagawa, Etsumori Harada
Journal of Pediatric Gastroenterology and Nutrition   24 242-252   Mar 1997
Background: Milk formulas for artificially reared (AR) rat pups are mostly based on complex cow's milk products, prepared by laborious and time- consuming processes. The aim of this study was to develop a simplified procedure for preparing a refin...
Tetsuro Matsuura, Isao Narama, Tetsu Nishikawa, Masahiko Nishimura, Tomohiro Imagawa, Hiroshi Kitagawa, Masato Uehara
Annals of Anatomy   179 277-283   Jan 1997
Morphological and morphometric examinations were conducted on skeletons of knotty-tail (knt/knt) mouse, a new autosomal recessive mutant. The knt/knt mice have short and knotty tails. The number of caudal vertebrae is reduced and their deformed ca...
T. Manabe; M. Yamashita; T. Kawashima; H. Okamoto; H. Kitagawa; T. Mitani; K. Toriumi; H. Miyamae; K. Inoue; K. Yakushi
Proceedings of SPIE - The International Society for Optical Engineering   3145 106-115   1997   [Refereed]
M. Nakaya; M. Kanehara; M. Yamauchi; H. Kitagawa; T. Teranishi
INTERMAG 2006 - IEEE International Magnetics Conference   466-   2006   [Refereed]
J.-I. Saito; K. Ara; K.-I. Sugiyama; H. Kitagawa; H. Nakano; K. Ogata; N. Yoshioka
International Conference on Nuclear Engineering, Proceedings, ICONE   1 559-563   2008   [Refereed]
R. Makiura; H. Kitagawa
Materials Research Society Symposium Proceedings   1312 491-496   2011   [Refereed]
Hiroshi Kitagawa, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   189 667-672   Dec 1996
A peculiar structure, observed as a dome-like protrusion at the apex of the caecum, was investigated macroscopically and histologically in healthy White Leghorn chickens. It was hemispheric or spherical in shape and as it consisted of a lumen with...
Kazuyuki Sugahara, Yukako Tanaka, Shuhei Yamada, Nobuko Seno, Hiroshi Kitagawa, Stuart M. Haslam, Howard R. Morris, Anne Dell
Journal of Biological Chemistry   271 26745-26754   Nov 1996
We prepared a series of oligosaccharides from king crab cartilage chondroitin sulfate K after exhaustive digestion with testicular hyaluronidase, and determined the structures of four tetrasaccharides and a pentasaccharide by fast atom bombardment...
Masato Uehara, Tomohiro Imagawa, Hiroshi Kitagawa
Journal of Anatomy   188 661-669   Jul 1996
Hyalocytes in the pecten oculi and ciliary body of adult chickens and their response to Escherichia coli were investigated by transmission and scanning electron microscopy and the inflammatory response following the intravitreous injection of coll...
H. Kitagawa, M. Ujikawa, K. Sugahara
Journal of Biological Chemistry   271 6583-6585   Apr 1996
Bovine, rat, and chicken UDP-GlcA:chondroitin glucuronyltransferase activities in sera during prenatal and postnatal development were systematically measured with polymeric chondroitin as an exogenous acceptor and with UDP-[ 14 C]GlcA as a donor. ...
Hiroyuki Yamada, Yoshinori Kawabata, Koji Ohtomo, Shouichi Sakamoto, Yutsuki Nakajima, Hiroshi Kitagawa, Isamu Sugawara
Japanese Journal of Lung Cancer   36 135-137   Apr 1996
In order to examine whether the antibody PC47H is useful to detect differentiation toward pulmonary adenocarcinoma, immunohistochemical examinations were undertaken comparing the results for antibody for CEA. Furthermore, antibodies for lactoferri...
Eric R. Sjoberg, Hiroshi Kitagawa, Hiroshi Kitagawa, John Glushka, Herman Van Halbeek, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   271 7450-7459   Mar 1996
A cDNA encoding a novel sialyltransferase has been isolated employing the polymerase chain reaction using degenerate primers to conserved regions of the sialylmotif that is present in all eukaryotic members of the sialyltransferase gene family exa...
Tomohiro Imagawa, Hiroshi Kitagawa, Masato Uehara
Journal of Anatomy   188 149-156   Mar 1996
Nerve fibres and their connections with chromaffin cells in the carp head kidney were studied by light and electron microscopy. Some nerve bundles entered the head kidney from the dorsal aspect along veins. Many unmyelinated axons emerged from the...
Hiroshi Kitagawa, Hiroshi Kitagawa, Marie Geneviève Mattei, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   271 931-938   Jan 1996
In this report we describe the chromosome mapping and genomic organization of the human Galβ1,3GalNAc/Galβ1,4GlcNAc α2,3-sialyltransferase gene. The gene is localized to human chromosome 11(q23-q24) by in situ hybridization of metaphase chromosome...
Osamu Ishihara, Hitomi Numari, Masahiro Saitoh, Yoshinori Arai, Hitoshi Takanashi, Hiroshi Kitagawa, Katsuyuki Kinoshita
Prostaglandins   52 199-208   Jan 1996
Previous reports revealed that interleukin-1(IL-1) was involved in the process of premature labor in the cases with intrauterine infection. However, the roles of the cytokine in normal spontaneous labor remain uncertain. The present studies aimed ...
Mark A. Williams, Hiroshi Kitagawa, Arun K. Datta, James C. Paulson, James C. Jamieson
Glycoconjugate Journal   12 755-761   Dec 1995
Values of K m were determined for three purified sialyltransferases and the corresponding recombinant enzymes. The enzymes were Galβ1-4GlcNAc α2-6sialyltransferase and Galβ1-3(4)GlcNAc α2-3sialyltransferase from rat liver; these enzymes are respo...
H. Kato, R. Matsuo, O. Komiyama, T. Tanaka, M. Inazu, H. Kitagawa, T. Yoneda, T. Yoneda
Gerontology   41 20-27   Jan 1995
Osteoporosis seen in aged individuals is represented by the reduced bone mass most likely resulting from decreased bone formation by osteoblasts. To examine whether aging causes a decrease in osteoblast activity, calvarial osteoblasts were iso lat...
M. Katoh, K. Kitamura, H. Kitagawa
Bone   16 97-102   Jan 1995
Unfractionated mouse long-bone cells prestimulated with rat parathyroid hormone (PTH) for 7 days (PTH-prestimulated long-bone cells; PTH-psLB cells) contained about 20% tartrate-resistant acid phosphatase (TRAP)-positive mononuclear cells and abou...
Hiroshi Kitagawa, Kazunori Tsuchida, Miho Ujikawa, Kazuyuki Sugahara
Journal of Biochemistry   117 1083-1087   Jan 1995
We report the occurrence, in bovine serum of a soluble form, of N-acetylgalactosaminyl-transferase activity, which is involved in chondroitin sulfate biosynthesis, and we describe a simple assay method for the enzyme. Chondroitin with the general ...
Hiroshi Kitagawa, Akiko Kinoshita, Kazuyuki Sugahara
Analytical Biochemistry   232 114-121   Jan 1995
A series of disaccharides derived from chondroitin sulfate and heparin/heparan sulfate were derivatized at their reducing ends with the fluorophore 2-amino-acridone. The resulting labeled compounds derived from chondroitin sulfate or heparin/hepar...
H. Kitagawa, Y. Tanaka, K. Tsuchida, F. Goto, T. Ogawa, K. Lidholt, U. Lindahl, K. Sugahara
Journal of Biological Chemistry   270 22190-22195   Jan 1995
During the course of a study to elucidate the role of modification of the common polysaccharide-protein linkage structure, GlcAβ1-3Galβ1-3Galβ1- 4Xylβ1-O-Ser, in biosynthetic sorting mechanisms of the different sulfated glycosaminoglycan chains, a...
T. Imagawa, H. Kitagawa, M. Uehara
Journal of Anatomy   185 521-528   Dec 1994
The ultrastructural features of blood vessels were examined by transmission and scanning electron microscopy in the perfused and nonperfused head kidney of the carp. They consisted mainly of the sinusoidal capillaries, arterioles, veins and portal...
Hiroshi Kitagawa, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   269 17872-17878   Jul 1994
Cell type-specific expression of specific carbohydrate structures on cell surface glycoproteins and glycolipids is increasingly recognized for providing information relevant to cell-cell interactions in developing and adult organisms. Sialyltransf...
Hiroshi Kitagawa, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   269 1394-1401   Jan 1994
Sialyltransferases are a family of 10-12 enzymes that catalyze the transfer of sialic acid to carbohydrate groups of glycoproteins and glycolipids. Three sialyltransferase cDNAs have been cloned, revealing a highly conserved sialylmotif in the cat...
Tomohiro Imagawa, Yasuhiro Kon, Hiroshi Kitagawa, Yoshiharu Hashimoto, Masato Uehara, Makoto Sugimura
Annals of Anatomy   176 175-179   Jan 1994
Appendices colli (App. colli) were investigated by anatomical and histological methods in the goat. App. colli were composed of elastic cartilage located at central and the skin covering the cartilage, which included arterioles along the cartilage...
Hiroshi Kimoto, Kazuyuki Kitamura, Kazuyuki Kitamura, Tetsuo Sudo, Tetsuo Sudo, Toshio Suda, Toshio Suda, Yasuki Ogawa, Yasuki Ogawa, Hiroshi Kitagawa, Hiroshi Kitagawa, Masaru Taniguchi, Masaru Taniguchi, Toshitada Takemori
International Immunology   5 1535-1540   Dec 1993
Immature hemopoietic cell lines were established by transforming fetal thymocytes in vitro with a ts mutant of Abelson murine leukemia virus. They are positive for c-kit and IL-2Rα but negative for lineage specific markers. Their TCR and Ig heavy ...
H. Kitagawa, J. C. Paulson
Biochemical and Biophysical Research Communications   194 375-382   Jul 1993
Here we report the cDNA sequence of human Galβ1,3(4)GlcNAc α2,3-sialyltransferase. The cDNA was isolated from a human placental cDNA library by screening with a 150bp probe generated by PCR using degenerate primers based on the sequences found in ...
Hiroyuki Yamada, Yoshinori Kawabata, Hiroshi Kitagawa, Shinji Itoyama, Isamu Sugawara
Acta Histochemica et Cytochemica   26 591-596   Jan 1993
The localization of fucosylceramide recognized by a monoclonal antibody (MAb), PC47H, was examined immunohistochemically using normal and cancerous tissues. Immunoreactive fucosylceramide was observed in pancreas, parathyroid, submandibular gland,...
M. Tsujisaki, Y. Hinoda, S. Tokuchi, Y. Hanzawa, Y. Arimura, J. Masuya, H. Kitagawa, E. Okochi, T. Shimamura, J. Hamuro, K. Imai, A. Yachi
Journal of Immunology   150 508-516   Jan 1993
Five anti-Id mAb (Ab2) were prepared from a BALB/c mouse immunized with anti-carcinoembryonic Ag (CEA) mAb MA208 (Ab1) in a syngeneic system. These anti-Id mAb appear to recognize unique idiotopes at the combining site of mAb MA208, because they w...
K. Kitamura, M. Katoh, O. Komiyama, H. Kitagawa, F. Matsubara, M. Kumegawa
Bone   14 829-834   Jan 1993
We established a useful assay system for evaluating osteoclast-mediated bone resorption based on the use of unfractionated bone cells obtained from 10- to 11-day-old mice. When cells from 10 to 11 mice were treated for 7 days with rat parathyroid ...
Hiroshi Kitagawa, Hiroshi Nakada, Shigeyuki Fukui, Ikuo Funakoshi, Toshisuke Kawasaki, Ikuo Yamashina, Shin Ichi Tate, Fuyuhiko Inagaki
Journal of Biochemistry   114 504-508   Jan 1993
Two novel oligosaccharides with the sialyl-Le a structure were isolated from human milk using a monoclonal antibody, MSW 113. These oligosaccharides were purified by affinity chromatography on a column of the immobilized monoclonal antibody and by...
Hisayoshi Nakamura, Hisayoshi Nakamura, Hiroyuki Yamada, Hiroshi Kitagawa, Atsuko Masunaga, Shinji Itoyama, Isamu Sugawara
Immunology Letters   37 119-122   Jan 1993
The reactivity of PC47H, a monoclonal antibody (mAb) directed against fucosylceramide, with cells of lymphoid lineage was examined. Immunoreactive fucosylceramide (FC) was recognized only in pokeweed mitogen (PWM)-stimulated B blasts, plasma cells...
T. Taniguchi, H. Kitagawa, S. Yasue, S. Yanagi, K. Sakai, M. Asahi, S. Ohta, F. Takeuchi, S. I. Nakamura, H. Yamamura
Journal of Biological Chemistry   268 2277-2279   Jan 1993
Activation of platelets by thrombin results in a dramatic increase in tyrosine phosphorylation on multiple cellular proteins (Ferrell, J. E., and Martin, G. S. (1988) Mol. Cell. Biol. 8, 3603-3610; Golden, A., and Brugge, J. S. (1989) Proc. Natl. ...
H. Kitagawa, H. Nakada, S. Fukui, I. Funakoshi, T. Kawasaki, S. I. Tate, F. Inagaki, I. Yamashina
Journal of Biological Chemistry   268 26541-26545   Jan 1993
Oligosaccharides were released from the gangliosides of a human rectal adenocarcinoma with endoglycoceramidase (Rhodococcus sp. G-74-2) and then purified by affinity chromatography on a column of an immobilized monoclonal antibody, MSW 113. Three ...
T. Katagiri, T. Suzuki, Y. Akiyama, T. Ishibashi, K. Hara, H. Oka, T. Imai, K. Kobayashi, H. Kitagawa, S. Ohno, M. Tanaka, F. Imai, Y. Dohi
Ryumachi   32 461-467   Jan 1992
A case of adult onset hypophosphatemic vitamin D resistant osteomalacia is described. A 40-year-old female who complained of thorax and lumbar pain and gait disturbance was admitted to our hospital on 7 November, 1988. The patient had hypophosphat...
H. Nakada, Y. Numata, M. Inoue, N. Tanaka, H. Kitagawa, I. Funakoshi, S. Fukui, I. Yamashina
Journal of Biological Chemistry   266 12402-12405   Sep 1991
To determine the epitopic structure for an anti-GalNAcα-Ser(Thr) (anti-Tn) monoclonal antibody, MLS 128, asialo-ovine submaxillary mucin was digested with various proteases, and the digests were fractionated by immunoaffinity column chromatography...
Hiroshi Nakada, Mizue Inoue, Nobuhiro Tanaka, Yoshito Numata, Hiroshi Kitagawa, Shigeyuki Fukui, Ikuo Yamashina
Biochemical and Biophysical Research Communications   179 762-767   Sep 1991
Expression of the Tn antigen on a T-lymphoid cell line, Jurkat, was investigated using an anti-Tn monoclonal antibody, MLS 128. Immunoprecipitation or immunoaffinity chromatography of a lysate of Jurkat cells led to the isolation of a 120 kDa glyc...
Hiroshi Kitagawa, Hiroshi Nakada, Shigeyuki Fukui, Toshisuke Kawasaki, Ikuo Yamashina
Biochemical and Biophysical Research Communications   178 1429-1436   Aug 1991
Oligosaccharides with the sialyl-Le a structure have been isolated on an affinity column of a monoclonal antibody, MSW 113, from mucin-type glycoproteins derived from the surfaces of SW 1116 and LS 180 cells, and their secretions. The oligosacchar...
Y. Kon, Y. Hashimoto, H. Kitagawa, M. Sugimura, K. Murakami
Journal of Anatomy   176 23-33   Jul 1991
Renin-containing cells in fetal adrenal glands of the mouse were investigated with the protein A-gold immunocytochemical technique. On Day 14 of gestation, a small number of specific granules were weakly immunoreactive and were distributed in the ...
Hiroshi Kitagawa, Hiroshi Nakada, Shigeyuki Fukui, Ikuo Funakoshi, Toshisuke Kawasaki, Ikuo Yamashina, Shinichi Tate, Fuyuhiko Inagaki
Biochemistry   30 2869-2876   Mar 1991
We have isolated four novel oligosaccharides with the sialyl-Le a structure from human milk using a monoclonal antibody, MSW 113. These oligosaccharides were purified by affinity chromatography on a column of the immobilized monoclonal antibody an...
Hiroshi Kitagawa, Mikiyo Takaoka, Hiroshi Nakada, Shigeyuki Fukui, Ikuo Funakoshi, Toshisuke Kawasaki, Shin ichi Tate, Fuyuhiko Inagaki, Ikuo Yamashina
Journal of Biochemistry   110 598-604   Jan 1991
We have determined the structures of six oligosaccharides isolated from human milk using a monoclonal antibody, MSW 113. The isolation involved affinity chromatography on a column of the immobilized monoclonal antibody and high-performance liquid ...
Shigeyuki Fukui, Hiroshi Nakada, Tomoyo Horie, Ikuo Funakoshi, Yoshito Numata, Ikuo Yamashina, Hiroshi Kitagawa, Toshisuke Kawasaki
Cancer Research   51 331-335   Jan 1991
Two monoclonal antibodies, MLS 102, which recognizes cancer-asso ciated mucin antigens, and MLS 103, which recognizes normal mucin, were used to isolate, by imunoaffinity chromatography, the correspond ing antigens from cell lysates and spent medi...
Yoshito Numata, Hiroshi Nakada, Shigeyuki Fukui, Hiroshi Kitagawa, Keiichi Ozaki, Mizue Inoue, Toshisuke Kawasaki, Ikuo Funakoshi, Ikuo Yamashina
Biochemical and Biophysical Research Communications   170 981-985   Aug 1990
A murine monoclonal antibody, MLS 128, that was assigned to an anti-Tn antibody has been established by immunizing mice with human colonic cancer cells (LS 180). MLS 128 bound to mucin glycopeptides from LS 180 cells and their asialo forms to the ...
S. Ohno, T. Suzuki, K. Hara, F. Imai, M. Tanaka, H. Kitagawa, T. Katagiri, K. Kobayashi, Y. Akiyama, Y. Doi
Japanese Journal of Allergology   39 701-707   Aug 1990
A 68-year-old man with suspected allergic granulomatosis and angiitis is reported. He had received 10 mg of prednisolone daily since July 1988 for asthma. He abruptly developed muscle weakness of the lower extremities, followed two days later by p...

Books etc

 
Caught in a Trap
M. Tanaka, H. Kitagawa
Riken Research, 3, 1-2   2008   
Recent Findings on Metal Nanoparticles as New-Type Hydrogen-Storage Material
H. Kobayashi, M. Yamauchi, H. Kitagawa, M. Takata
Spring-8 Research Frontiers 2008, 68-69   2009   

Works

 
Creation of Hydrogen Storage Polymer
2000

Research Grants & Projects

 
A New Two-Band system of d and π with interband H-Bridges
Physical properties in Perovskite-type Mixed-Valence Transition-Metal Compounds
Oreation of a Hydrogen-Storage polymer
Hydrogen Strage
Proton Conductor