北川 宏

J-GLOBALへ         更新日: 18/06/06 12:45
 
アバター
研究者氏名
北川 宏
 
キタガワ ヒロシ
所属
京都大学
部署
大学院理学研究科
職名
教授
学位
(理学)博士(京都大学), 理学修士(京都大学)

研究分野

 
 

経歴

 
1991年
 - 
1994年
岡崎国立共同研究機構分子科学研究所 助手
 
1994年
 - 
2000年
北陸先端大 助手
 
2000年
 - 
2003年
筑波大学化学系 助教授
 
 
   
 
0000- 北陸先端大 助教授 (客員)
 
2003年
   
 
-九州大学大学院理学研究院化学部門 教授
 

学歴

 
 
 - 
1991年
京都大学 理学研究科 化学
 
 
 - 
1986年
京都大学 理学部 化学(専攻)
 

論文

 
Aoki K, Otsubo K, Hanan GS, Sugimoto K, Kitagawa H
Inorganic chemistry   57(11) 6222-6225   2018年6月   [査読有り]
Konarev DV, Kuzmin AV, Khasanov SS, Litvinov AL, Otsuka A, Yamochi H, Kitagawa H, Lyubovskaya RN
Chemistry, an Asian journal      2018年5月   [査読有り]
Song C, Yang A, Sakata O, Kumara LSR, Hiroi S, Cui YT, Kusada K, Kobayashi H, Kitagawa H
Physical chemistry chemical physics : PCCP      2018年5月   [査読有り]
Nadanaka S, Kitagawa H
Biochimica et biophysica acta   1862(4) 791-799   2018年4月   [査読有り]
Haraguchi Tomoyuki, Otsubo Kazuya, Kitagawa Hiroshi
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (16) 1697-1706   2018年4月   [査読有り]
Taylor Jared M., Dwyer Patrick J., Reid Joel W., Gelfand Benjamin S., Lim Dae-woon, Donoshita Masaki, Veinberg Stanislav L., Kitagawa Hiroshi, Vukotic V. Nicholas, Shimizu George K. H.
CHEM   4(4) 868-878   2018年4月   [査読有り]
Matsuki Masaya, Yamada Teppei, Dekura Shun, Kitagawa Hiroshi, Kimizuka Nobuo
CHEMISTRY LETTERS   47(4) 497-499   2018年4月   [査読有り]
Wang F, Kusada K, Wu D, Yamamoto T, Toriyama T, Matsumura S, Nanba Y, Koyama M, Kitagawa H
Angewandte Chemie (International ed. in English)   57(17) 4505-4509   2018年4月   [査読有り]
Zhang Quan, Kusada Kohei, Wu Dongshuang, Kawaguchi Shogo, Kubota Yoshiki, Kitagawa Hiroshi
CHEMISTRY LETTERS   47(4) 559-561   2018年4月   [査読有り]
Yamamoto A, Omotehara T, Miura Y, Takada T, Yoneda N, Hirano T, Mantani Y, Kitagawa H, Yokoyama T, Hoshi N
The Journal of veterinary medical science   80(4) 557-567   2018年4月   [査読有り]
Yoneda N, Takada T, Hirano T, Yanai S, Yamamoto A, Mantani Y, Yokoyama T, Kitagawa H, Tabuchi Y, Hoshi N
The Journal of veterinary medical science   80(4) 634-637   2018年4月   [査読有り]
Masuda N, Mantani Y, Yuasa H, Yoshitomi C, Arai M, Nishida M, Qi WM, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   80(3) 395-404   2018年3月   [査読有り]
Masuda N, Mantani Y, Yoshitomi C, Yuasa H, Nishida M, Arai M, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   80(2) 323-332   2018年3月   [査読有り]
Takada T, Yoneda N, Hirano T, Yanai S, Yamamoto A, Mantani Y, Yokoyama T, Kitagawa H, Tabuchi Y, Hoshi N
The Journal of veterinary medical science   80(4) 720-724   2018年4月   [査読有り]
Matsuki Masaya, Yamada Teppei, Yasuda Nobuhiro, Dekura Shun, Kitagawa Hiroshi, Kimizuka Nobuo
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   140(1) 291-297   2018年1月   [査読有り]
Intra-tumoral 8-OHdG is a novel prognostic factor in advanced colon cancer
Kitagawa Hiroshi, Kitajima Yoshihiko, Nakamura Jun, Tanaka Tomokazu, Koga Yasuo, Manabe Tatsuya, Noshiro Hirokazu
CANCER SCIENCE   109 579   2018年1月   [査読有り]
Konarev Dmitri V., Khasanov Salavat S., Troyanov Sergey I., Otsuka Akihiro, Yamochi Hideki, Kitagawa Hiroshi, Lyubovskaya Rimma N.
CHEMISTRYSELECT   2(23) 6640-6644   2017年8月   [査読有り]
Kobayashi H, Kusada K, Kitagawa H
Accounts of chemical research   48(6) 1551-1559   2015年6月   [査読有り]
Nishida Yoshihide, Sato Katsutoshi, Yamamoto Tomokazu, Wu Dongshuang, Kusada Kohei, Kobayashi Hirokazu, Matsumura Syo, Kitagawa Hiroshi, Nagaoka Katsutoshi
CHEMISTRY LETTERS   46(8) 1254-1257   2017年8月   [査読有り]
Sakaida Shun, Otsubo Kazuya, Sakata Osami, Song Chulho, Fujiwara Akihiko, Takata Masaki, Kitagawa Hiroshi
NATURE CHEMISTRY   8(4) 377-383   2016年4月   [査読有り]
Mito-oka Yasuko, Sawada Yuki, Masumori Tadao, Horike Satoshi, Kitagawa Hiroshi, Kitagawa Susumu
CHEMISTRY LETTERS   44(12) 1694-1696   2015年12月   [査読有り]
Kutubi Md. Shahajahan, Sato Katsutoshi, Wada Kenji, Yamamoto Tomokazu, Matsumura Syo, Kusada Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi, Nagaoka Katsutoshi
CHEMCATCHEM   7(23) 3887-3894   2015年12月   [査読有り]
Hirano T, Yanai S, Omotehara T, Hashimoto R, Umemura Y, Kubota N, Minami K, Nagahara D, Matsuo E, Aihara Y, Shinohara R, Furuyashiki T, Mantani Y, Yokoyama T, Kitagawa H, Hoshi N
The Journal of veterinary medical science   77(10) 1207-1215   2015年10月   [査読有り]
Mikami T, Kitagawa H
Glycoconjugate journal   34(6) 725-735   2017年12月   [査読有り]
Otsubo Kazuya, Kitagawa Hiroshi
APL MATERIALS   2(12)    2014年12月   [査読有り]
A novel HNK-1 epitope in perineuronal nets
Yabuno Keiko, Izumikawa Tomomi, Takematsu Hiromu, Kitagawa Hiroshi, Oka Shogo
GLYCOBIOLOGY   24(11) 1148-1149   2014年11月   [査読有り]
Fujie K, Yamada T, Ikeda R, Kitagawa H
Angewandte Chemie (International ed. in English)   53(42) 11302-11305   2014年10月   [査読有り]
Konarev Dmitri V., Kuzmin Alexey V., Khasanov Salavat S., Batov Mikhail S., Otsuka Akihiro, Yamochi Hideki, Kitagawa Hiroshi, Lyubovskaya Rimma N.
CRYSTENGCOMM   20(4) 385-401   2018年1月   [査読有り]
Partial Discharge Inception Voltage Measurements of Ester Dielectric Fluid for Insulation Diagnosis
2017 6TH INTERNATIONAL YOUTH CONFERENCE ON ENERGY (IYCE)      2017年   [査読有り]
Mitsuka Yuko, Nagashima Kazuro, Kobayashi Hirokazu, Kitagawa Hiroshi
CHEMISTRY LETTERS   45(11) 1313-1315   2016年11月   [査読有り]
Dietzel Pascal D. C., Kitagawa Hiroshi
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (27) 4273-4274   2016年9月   [査読有り]
Bao Song-Song, Li Nan-Zhu, Taylor Jared M., Shen Yang, Kitagawa Hiroshi, Zheng Li-Min
CHEMISTRY OF MATERIALS   27(23) 8116-8125   2015年12月   [査読有り]
Fujie Kazuyuki, Ikeda Ryuichi, Otsubo Kazuya, Yamada Teppei, Kitagawa Hiroshi
CHEMISTRY OF MATERIALS   27(21) 7355-7361   2015年11月   [査読有り]
Hirano T, Kobayashi Y, Omotehara T, Tatsumi A, Hashimoto R, Umemura Y, Nagahara D, Mantani Y, Yokoyama T, Kitagawa H, Hoshi N
The Journal of veterinary medical science   76(9) 1201-1208   2014年9月   [査読有り]
Sadakiyo Masaaki, Yamada Teppei, Kitagawa Hiroshi
CHEMPLUSCHEM   81(8) 691-701   2016年8月   [査読有り]
Yutsudo N, Kitagawa H
Experimental neurology   274(Pt B) 126-133   2015年12月   [査読有り]
Deficient mieap expression increases invasion ability via impairment of MQC in gastric cancer cells under hypoxia
Okuyama Keiichiro, Kitajima Yoshihiko, Tanaka Tomokazu, Nakamura Jun, Kitagawa Hiroshi, Egawa Noriyuki, Yanagihara Kazuyoshi, Nakamura Yasuyuki, Arakawa Hirofumi, Noshiro Hirokazu
CANCER SCIENCE   109 874   2018年1月   [査読有り]
Konarev Dmitri V., Kuzmin Alexey V., Khasanov Salavat S., Troyanov Sergey I., Otsuka Akihiro, Yamochi Hideki, Kitagawa Hiroshi, Lyubovskaya Rimma N.
ORGANOMETALLICS   36(20) 4032-4037   2017年10月   [査読有り]
Miyata S, Kitagawa H
Biochimica et biophysica acta   1861(10) 2420-2434   2017年10月   [査読有り]
Mieap expression is associated with MQC integrity and controls ROS production in gastric cancer cells under hypoxia
Kitajima Yoshihiko, Okuyama Keiichiro, Tanaka Tomokazu, Nakamura Jun, Kitagawa Hiroshi, Egawa Noriyuki, Yanagihara Kazuyoshi, Nakamura Yasuyuki, Arakawa Hirofumi, Noshiro Hirokazu
CANCER SCIENCE   109 909   2018年1月   [査読有り]
Seo Okkyun, Sakata Osami, Kim Jae Myung, Hiroi Satoshi, Song Chulho, Kumara Loku Singgappulige Rosantha, Ohara Koji, Dekura Shun, Kusada Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi
APPLIED PHYSICS LETTERS   111(25)    2017年12月   [査読有り]
Dekura Shun, Kobayashi Hirokazu, Li Guangqin, Ikeda Ryuichi, Kubota Yoshiki, Takata Masaki, Kitagawa Hiroshi
CHEMISTRY LETTERS   43(8) 1363-1364   2014年8月   [査読有り]
Li Guangqin, Kobayashi Hirokazu, Taylor Jared M., Ikeda Ryuichi, Kubota Yoshiki, Kato Kenichi, Takata Masaki, Yamamoto Tomokazu, Toh Shoichi, Matsumura Syo, Kitagawa Hiroshi
NATURE MATERIALS   13(8) 802-806   2014年8月   [査読有り]
Bao SS, Otsubo K, Taylor JM, Jiang Z, Zheng LM, Kitagawa H
Journal of the American Chemical Society   136(26) 9292-9295   2014年7月   [査読有り]
Takeda Norihiko, Ueda Masafumi, Mori Nagisa, Miyoshi Tetsuya, Shimoda Manami, Uno Yumina, Kitagawa Hiroshi, Emoto Noriaki, Mukai Takahiro, Miyata Okiko
HETEROCYCLES   94(4) 750-+   2017年4月   [査読有り]
Omotehara Takuya, Minami Kiichi, Mantani Youhei, Umemura Yuria, Nishida Miho, Hirano Tetsushi, Yoshioka Hidefumi, Kitagawa Hiroshi, Yokoyama Toshifumi, Hoshi Nobuhiko
DEVELOPMENTAL DYNAMICS   246(2) 148-156   2017年2月   [査読有り]
Isfahani Ali Pournaghshband, Ghalei Behnam, Bagheri Rouhollah, Kinoshita Yosuke, Kitagawa Hiroshi, Sivaniah Easan, Sadeghi Morteza
JOURNAL OF MEMBRANE SCIENCE   513 58-66   2016年9月   [査読有り]
Kawaguchi Genta, Maesato Mitsuhiko, Komatsu Tokutaro, Imakubo Tatsuro, Kitagawa Hiroshi
PHYSICAL REVIEW B   93(7)    2016年2月   [査読有り]
Yamada Teppei, Sadakiyo Masaaki, Shigematsu Akihito, Kitagawa Hiroshi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN   89(1) 1-10   2016年1月   [査読有り]
Mantani Youhei, Ito Eri, Nishida Miho, Yuasa Hideto, Masuda Natsumi, Qi Wang-Mei, Kawano Junichi, Yokoyama Toshifumi, Hoshi Nobuhiko, Kitagawa Hiroshi
JOURNAL OF VETERINARY MEDICAL SCIENCE   77(9) 1121-1128   2015年9月   [査読有り]
Akiba Hiroshi, Kobayashi Hirokazu, Kitagawa Hiroshi, Kofu Maiko, Yamamuro Osamu
PHYSICAL REVIEW B   92(6)    2015年8月   [査読有り]
Tanaka Ryoji, Yokoyama Tetsuya, Kitagawa Hiroshi, Tesfaye Demissie Bizuneh, Nakamura Eizo
CHEMICAL GEOLOGY   396 255-264   2015年3月   [査読有り]
Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H
Scientific reports   5 8994   2015年3月   [査読有り]
Roesler Christoph, Esken Daniel, Wiktor Christian, Kobayashi Hirokazu, Yamamoto Tomokazu, Matsumura Syo, Kitagawa Hiroshi, Fischer Roland A.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (32) 5514-5521   2014年11月   [査読有り]
Izumikawa T, Sato B, Mikami T, Tamura J, Igarashi M, Kitagawa H
The Journal of biological chemistry   290(9) 5438-5448   2015年2月   [査読有り]
Takahara E, Yuasa H, Nishida M, Mantani Y, Udayanga KG, Qi WM, Takeuchi T, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   77(4) 387-393   2015年4月   [査読有り]
Ōkawa H, Sadakiyo M, Otsubo K, Yoneda K, Yamada T, Ohba M, Kitagawa H
Inorganic chemistry   54(17) 8529-8535   2015年9月   [査読有り]
Heparan Sulfate Containing Unsubstituted Glucosamine Residues: Biosynthesis and Heparanase Inhibitory Activity
Nadanaka Satomi, Purunomo Eko, Takeda Naoko, Tamura Jun-ichi, Kitagawa Hiroshi
GLYCOBIOLOGY   24(11) 1206   2014年11月   [査読有り]
Yang Anli, Sakata Osami, Kusada Kohei, Yayama Tomoe, Yoshikawa Hideki, Ishimoto Takayoshi, Koyama Michihisa, Kobayashi Hirokazu, Kitagawa Hiroshi
APPLIED PHYSICS LETTERS   105(15)    2014年10月   [査読有り]
Sadakiyo M, Yamada T, Kitagawa H
Journal of the American Chemical Society   136(38) 13166-13169   2014年9月   [査読有り]
Tadokoro M, Ohhata Y, Shimazaki Y, Ishimaru S, Yamada T, Nagao Y, Sugaya T, Isoda K, Suzuki Y, Kitagawa H, Matsui H
Chemistry (Weinheim an der Bergstrasse, Germany)   20(42) 13698-13709   2014年10月   [査読有り]
Yamamoto T, Kobayashi H, Kumara LSR, Sakata O, Nitta K, Uruga T, Kitagawa H
Nano letters   17(9) 5273-5276   2017年9月   [査読有り]
Otsubo Kazuya, Haraguchi Tomoyuki, Kitagawa Hiroshi
COORDINATION CHEMISTRY REVIEWS   346 123-138   2017年9月   [査読有り]
Kofu Maiko, Hashimoto Naoki, Akiba Hiroshi, Kobayashi Hirokazu, Kitagawa Hiroshi, Iida Kazuki, Nakamura Mitsutaka, Yamamuro Osamu
PHYSICAL REVIEW B   96(5)    2017年8月   [査読有り]
Kawaguchi Genta, Maesato Mitsuhiko, Komatsu Tokutaro, Imakubo Tatsuro, Kiswandh Andhika, Graf David, Kitagawa Hiroshi
CHEMISTRY OF MATERIALS   28(20) 7276-7286   2016年10月   [査読有り]
Otsubo Kazuya, Suto Tomohiko, Kobayashi Atsushi, Ikeda Ryuichi, Hedo Masato, Uwatoko Yoshiya, Kitagawa Hiroshi
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY   (27) 4402-4407   2016年9月   [査読有り]
Kofu Maiko, Hashimoto Naoki, Akiba Hiroshi, Kobayashi Hirokazu, Kitagawa Hiroshi, Tyagi Madhusudan, Faraone Antonio, Copley John R. D., Lohstroh Wiebke, Yamamuro Osamu
PHYSICAL REVIEW B   94(6)    2016年8月   [査読有り]
Fujie Kazuyuki, Kitagawa Hiroshi
COORDINATION CHEMISTRY REVIEWS   307 382-390   2016年1月   [査読有り]
Umemura Y, Miyamoto R, Hashimoto R, Kinoshita K, Omotehara T, Nagahara D, Hirano T, Kubota N, Minami K, Yanai S, Masuda N, Yuasa H, Mantani Y, Matsuo E, Yokoyama T, Kitagawa H, Hoshi N
The Journal of veterinary medical science   77(12) 1587-1598   2016年1月   [査読有り]
Sadakiyo Masaaki, Yamada Teppei, Kitagawa Hiroshi
INORGANIC CHEMISTRY COMMUNICATIONS   72 138-140   2016年10月   [査読有り]
Kobayashi K, Kobayashi H, Maesato M, Hayashi M, Yamamoto T, Yoshioka S, Matsumura S, Sugiyama T, Kawaguchi S, Kubota Y, Nakanishi H, Kitagawa H
Angewandte Chemie (International ed. in English)   56(23) 6578-6582   2017年6月   [査読有り]
Sadakiyo Masaaki, Yamada Teppei, Kato Kenichi, Takata Masaki, Kitagawa Hiroshi
CHEMICAL SCIENCE   7(2) 1349-1356   2016年   [査読有り]
Sakaida S, Haraguchi T, Otsubo K, Sakata O, Fujiwara A, Kitagawa H
Inorganic chemistry   56(14) 7606-7609   2017年7月   [査読有り]
Kumara L. S. R., Sakata Osami, Kohara Shinji, Yang Anli, Song Chulho, Kusada Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi
PROCEEDINGS OF THE 12TH INTERNATIONAL CONFERENCE ON SYNCHROTRON RADIATION INSTRUMENTATION (SRI2015)   1741    2016年   [査読有り]
Taniguchi M, Nadanaka S, Tanakura S, Sawaguchi S, Midori S, Kawai Y, Yamaguchi S, Shimada Y, Nakamura Y, Matsumura Y, Fujita N, Araki N, Yamamoto M, Oku M, Wakabayashi S, Kitagawa H, Yoshida H
Cell structure and function   40(1) 13-30   2015年   [査読有り]
Pineda-Velasco Ivan, Nguyen Tai T., Kitagawa Hiroshi, Nakamura Eizo
GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS   16(9) 2848-2852   2015年9月   [査読有り]
Taylor Jared M., Dekura Shun, Ikeda Ryuichi, Kitagawa Hiroshi
CHEMISTRY OF MATERIALS   27(7) 2286-2289   2015年4月   [査読有り]
Element strategy for new nanomaterials
Kitagawa Hiroshi
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   249    2015年3月   [査読有り]
Watanabe Y, Haraguchi T, Otsubo K, Sakata O, Fujiwara A, Kitagawa H
Chemical communications (Cambridge, England)   53(73) 10112-10115   2017年9月   [査読有り]
Krishnan Karthik, Yamada Tomoaki, Iwatsuki Hiroko, Hara Mitsuo, Nagano Shusaku, Otsubo Kazuya, Sakata Osami, Fujiwara Akihiko, Kitagawa Hiroshi, Nagao Yuki
ELECTROCHEMISTRY   82(10) 865-869   2014年10月   [査読有り]
Huang Bo, Kobayashi Hirokazu, Kitagawa Hiroshi
CHEMISTRY LETTERS   43(9) 1459-1460   2014年9月   [査読有り]
Takaishi S, Kitagawa H, Tanaka H, Kuroda S, Ikeda R
Dalton transactions (Cambridge, England : 2003)   43(30) 11529-11532   2014年8月   [査読有り]
Miyata S, Kitagawa H
Journal of biochemistry   157(1) 13-22   2015年1月   [査読有り]
Mantani Y, Yuasa H, Nishida M, Takahara E, Omotehara T, Udayanga KG, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   76(6) 833-838   2014年6月   [査読有り]
Mantani Y, Ito E, Nishida M, Yuasa H, Masuda N, Qi WM, Kawano J, Yokoyama T, Hoshi N, Kitagawa H
The Journal of veterinary medical science   77(9) 1121-1128   2015年9月   [査読有り]
Schiavi Federica, Rosciglione Alberto, Kitagawa Hiroshi, Kobayashi Katsura, Nakamura Eizo, Nuccio Pasquale Mario, Ottolini Luisa, Paonita Antonio, Vannucci Riccardo
GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS   16(7) 2109-2126   2015年7月   [査読有り]
Matsushita K, Nakata T, Takeda-Okuda N, Nadanaka S, Kitagawa H, Tamura JI
Bioorganic & medicinal chemistry   26(5) 1016-1025   2018年3月   [査読有り]
Kinouchi H, Arimoto H, Nishiguchi K, Oka M, Maki H, Kitagawa H, Kamimori H
Analytical biochemistry   452 67-75   2014年5月   [査読有り]
Uchida Sayaka, Ogasawara Yoshiyuki, Maruichi Toshiaki, Kumamoto Akihito, Ikuhara Yuichi, Yamada Teppei, Kitagawa Hiroshi, Mizuno Noritaka
CRYSTAL GROWTH & DESIGN   14(12) 6620-6626   2014年12月   [査読有り]
Hashiguchi R, Otsubo K, Maesato M, Sugimoto K, Fujiwara A, Kitagawa H
Angewandte Chemie (International ed. in English)   56(14) 3838-3841   2017年3月   [査読有り]
Inagaki Yuji, Sakamoto Yasutaka, Morodomi Hiroki, Kawae Tatsuya, Yoshida Yasuo, Asano Takayuki, Hosoi Kohei, Kobayashi Hirokazu, Kitagawa Hiroshi, Ajiro Yoshitami, Furukawa Yuji
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN   83(5)    2014年5月   [査読有り]
Konarev DV, Kuzmin AV, Khasanov SS, Shestakov AF, Yudanova EI, Otsuka A, Yamochi H, Kitagawa H, Lyubovskaya RN
The Journal of organic chemistry   83(4) 1861-1866   2018年2月   [査読有り]
Miyamoto K, Tanaka N, Moriguchi K, Ueno R, Kadomatsu K, Kitagawa H, Kusunoki S
Glycobiology   24(5) 469-475   2014年5月   [査読有り]
Highly sulfated chondroitin sulfate chains regulate neuronal polarity formation
Mikami Tadahisa, Shida Miharu, Kitagawa Hiroshi
GLYCOBIOLOGY   24(11) 1153-1154   2014年11月   [査読有り]
Yamada T, Shirai Y, Kitagawa H
Chemistry, an Asian journal   9(5) 1316-1320   2014年5月   [査読有り]
Regulatory mechanism of chondroitin sulfate-mediated axon guidance
Nakamura Masao, Tamura Jun-ichi, Kitagawa Hiroshi, Tojima Takuro, Kamiguchi Hiroyuki
GLYCOBIOLOGY   24(11) 1158   2014年11月   [査読有り]
Kawaguchi G, Maesato M, Komatsu T, Kitagawa H, Imakubo T, Kiswandhi A, Graf D, Brooks JS
Angewandte Chemie (International ed. in English)   54(35) 10169-10172   2015年8月   [査読有り]
Huang B, Kobayashi H, Yamamoto T, Matsumura S, Nishida Y, Sato K, Nagaoka K, Kawaguchi S, Kubota Y, Kitagawa H
Journal of the American Chemical Society   139(13) 4643-4646   2017年4月   [査読有り]
Yamamoto Takayuki, Kobayashi Hirokazu, Kitagawa Hiroshi
CHEMISTRY LETTERS   43(8) 1355-1356   2014年8月   [査読有り]

Misc

 
K. G.S. Udayanga, H. Miyata, Y. Yokoo, W. M. Qi, E. Takahara, Y. Mantani, T. Yokoyama, N. Hoshi, H. Kitagawa
Histology and Histopathology   26 811-820   2011年7月
Epidermal homeostasis is maintained by both epithelial proliferation in the stratum basale (SB) and the apoptosis of epithelial cells under physiological conditions. In this study, the induction and regulation mechanisms of epidermal apoptosis wer...
A. Sano, H. Kage, K. Sugimoto, H. Kitagawa, N. Aki, A. Goto, M. Fukayama, J. Nakajima, S. Takamoto, T. Nagase, Y. Yatomi, N. Ohishi, D. Takai, D. Takai
Oncogene   26 6518-6525   2007年10月
Cancer-specific gene promoter methylation has been described in many types of cancers, and various semi-quantified results have shown their usefulness. Here, we show a more sensitive and specific second-generation system for profiling the DNA meth...
Shuji Mizumoto, Hiroshi Kitagawa, Kazuyuki Sugahara
Chemistry and Biology of Heparin and Heparan Sulfate   203-243   2005年12月
This chapter focuses on recent advances in the study of the biosynthesis and the functions of heparin (HP) and heparan sulfate (HS). They are structurally the most complex species of the glycosaminoglycan (GAG) family. During the synthesis of the ...
Hiroshi Kitagawa, Hiroshi Kitagawa, Akiteru Goto, Manabu Minami, Jun Nakajima, Toshiro Niki, Masashi Fukayama
Japanese Journal of Clinical Oncology   33 541   2003年10月
J. H. Lee, S. K. Ku, Hyeung Sik Lee, H. Kitagawa
European Journal of Histochemistry   47 165-172   2003年6月
The regional distribution and frequency of pancreatic endocrine cells in the red-bellied frog, Bombina orientalis, were studied by the immunohistochemical peroxidase antiperoxidase (PAP) method using five types of specific mammalian antisera to in...
Byung Taek Kim, Hiroshi Kitagawa, Kazuyuki Sugahara
Connective Tissue   34 261-265   2002年9月
Hereditary multiple exostoses, (HME) are benign bone tumors genetically associated with mutations in either EXT1 or EXT2, both of which have tumor suppressor functions. Subsequent cloning of three EXT-like genes, EXTL1, EXTL2 and EXTL3, has reveal...
K. Sugahara, S. Yamada, H. Kitagawa
Seikagaku   73 458-470   2001年12月
Hiroshi Kitagawa, Toru Uyama, Kazuyuki Sugahara
Journal of Biological Chemistry   276 38721-38726   2001年10月
We have identified a human chondroitin synthase from the HUGE (human unidentified gene-encoded large proteins) protein data base by screening with two keywords: "one transmembrane domain" and " galactosyltransferase family." The identified protein...
H. Kitagawa, M. Taoka, Y. Tone, K. Sugahara
Biochemical Journal   358 539-546   2001年9月
Here we describe the characterization of the human glycosaminoglycan glucuronyltransferase I gene (GlcAT-I) and a related pseudogene. The GlcAT-I gene was localized to human chromosome 11q12-q13 by in situ hybridization of metaphase chromosomes. G...
Byung Taek Kim, Hiroshi Kitagawa, Jun Ichi Tamura, Toshiyuki Saito, Marion Kusche-Gullberg, Ulf Lindahl, Kazuyuki Sugahara, Kazuyuki Sugahara
Proceedings of the National Academy of Sciences of the United States of America   98 7176-7181   2001年6月
The tumor suppressors EXT1 and EXT2 are associated with hereditary multiple exostoses and encode bifunctional glycosyltransferases essential for chain polymerization of heparan sulfate (HS) and its analog, heparin (Hep). Three highly homologous EX...
Jun Ichi Tamura, Hirofumi Urashima, Kazunori Tsuchida, Hiroshi Kitagawa, Kazuyuki Sugahara
Carbohydrate Research   332 41-51   2001年5月
Newly designed linear-type glycoclusters were synthesized which involve a chondroitin repeating disaccharide ligand and a hydrophobic octyl ether spacer. The spacer mimics the corresponding disaccharide unit. Repeating elongation of the pseudo-tet...
Hiroshi Kitagawa, Noriyuki Egusa, Jun Ichi Tamura, Marion Kusche-Gullberg, Ulf Lindahl, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   276 4834-4838   2001年2月
The proteins encoded by the EXT1, EXT2, and EXTL2 genes, members of the hereditary multiple exostoses gene family of tumor suppressors, are glycosyltransferases required for the heparan sulfate biosynthesis. Only two homologous genes, rib-1 and ri...
T. Murakawa, J. Nakajima, M. Tanaka, S. Takamoto, H. Kitagawa, M. Fukayama
Kyobu geka. The Japanese journal of thoracic surgery   54 829-834   2001年1月
A 78-year-old asymptomatic woman was referred to our department for the treatment of a right lung tumor. The patient had been suffering from rheumatoid arthritis and followed up in outpatient clinic. On March 6, 1995, abnormal shadow in the right ...
Hiroshi Kitagawa, Hiroshi Kitagawa, Shigekazu Shiraishi, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   197 607-616   2000年12月
To clarify the nature of M cells, the detailed ultrastructural characteristics and lectin-binding properties of M cells were investigated in follicle-associated epithelium (FAE) of chicken caecal tonsils. M cells presented various outlines from co...
Lars C. Pedersen, Kazunori Tsuchida, Hiroshi Kitagawa, Kazuyuki Sugahara, Thomas A. Darden, Masahiko Negishi
Journal of Biological Chemistry   275 34580-34585   2000年11月
Human β1,3-glucuronyltransferase I (GlcAT-I) is a central enzyme in the initial steps of proteoglycan synthesis. GlcAT-I transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisa...
Hiromi Sakaguchi, Hiroshi Kitagawa, Kazuyuki Sugahara
Biochimica et Biophysica Acta - General Subjects   1523 269-276   2000年10月
The cDNA and gene encoding human N-acetylglucosamine-6-O-sulfotransferase (Gn6ST) have been cloned. Comparative analysis of this cDNA with the mouse Gn6ST sequence indicates 96% amino acid identity between the two sequences. The expression of a so...
Masakatsu Yamamoto, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara, Masato Uehara
Brain Research Bulletin   52 537-546   2000年8月
The organization of spinocerebellar tract (SCT) neurons in the chicken was studied quantitatively using retrograde wheat germ agglutinin-horseradish peroxidase labelling. The chicken spinal cord was divided into five regions based on the distribut...
Hiroshi Kitagawa, Masaki Fujita, Nobue Ito, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   275 21075-21080   2000年7月
A novel human chondroitin 6-O-sulfotransferase, designated C6ST-2, was identified by BLAST analysis of expressed sequence tag using the sequence of a previously described human chondroitin 6-O-sultotransferase (C6ST-1) as a probe. The new cDNA seq...
Masato Uehara, Masato Uehara, Kazuhiko Taguchi, Tomohiro Imagawa, Hiroshi Kitagawa
Journal of Morphology   244 15-22   2000年4月
The spinal cords of vertebrates are generally divided into the cord proper and the minute filum terminale. While the spinal cord extends the entire length of the vertebral canal in the adult tiger puffer, Takifugu rubripes, the cord proper is grea...
Kazuyuki Sugahara, Hiroshi Kitagawa
Current Opinion in Structural Biology   10 518-527   2000年1月
Recent cDNA cloning of the glycosyltransferases involved in the synthesis of the sulfated glycosaminoglycan sidechains of proteoglycans has provided important clues to answering long-standing questions concerning the mechanisms of both chain polym...
Claire Senay, Thomas Lind, Kumi Muguruma, Yuko Tone, Hiroshi Kitagawa, Kazuyuki Sugahara, Kerstin Lidholt, Ulf Lindahl, Marion Kusche-Gullberg
EMBO Reports   1 282-286   2000年1月
The D-glucuronyltransferase and N-acetyl-D-glucosaminyl-transferase reactions in heparan sulfate biosynthesis have been associated with two genes, EXT1 and EXT2, which are also implicated in the inherited bone disorder, multiple exostoses. Since t...
H. Kitagawa, K. Sugahara
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   45 579-586   2000年1月
Etsumori Harada, Yoshinori Itoh, Kiitiro Sitizyo, Takashi Takeuchi, Yumi Araki, Hiroshi Kitagawa
Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology   124 321-327   1999年11月
Lactoferrin is a major iron-binding protein in milk from several species, such as humans, monkeys, mice and sows. Using neonatal and weaner piglets, the characteristic transfer of lactoferrin from intestinal lumen into bile via the circulation was...
Shuhei Yamada, Irma Van Die, Dirk H. Van Den Eijnden, Akiko Yokota, Hiroshi Kitagawa, Kazuyuki Sugahara
FEBS Letters   459 327-331   1999年10月
A considerable amount (approximately 1.6 μg from 1 mg of dried nematode) of non-sulfated chondroitin, two orders of magnitude less yet an appreciable amount of heparan sulfate, and no hyaluronate were found in Caenorhabditis elegans nematodes. The...
Yuko Tone, Hiroshi Kitagawa, Kimiyuki Imiya, Shogo Oka, Toshisuke Kawasaki, Kazuyuki Sugahara
FEBS Letters   459 415-420   1999年10月
We characterized the recombinant glucuronyltransferase I (GlcAT-I) involved in the glycosaminoglycan-protein linkage region biosynthesis. The enzyme showed strict specificity for Galβ1-3Galβ1-4Xyl, exhibiting negligible incorporation into other ga...
Kazunori Tsuchida, Thomas Lind, Hiroshi Kitagawa, Ulf Lindahl, Kazuyuki Sugahara, Kazuyuki Sugahara, Kerstin Lidholt
European Journal of Biochemistry   264 461-467   1999年9月
β-N-Acetylgalactosaminyltransferase II and β-glucuronyltransferase II, involved in chondroitin sulfate biosynthesis, transfer an N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) residue, respectively, through β-linkages to an acceptor ch...
Tomohiro Imagawa, Yuko Fujita, Hiroshi Kitagawa, Masato Uehara
Journal of Veterinary Medical Science   61 883-889   1999年8月
The optic nerve fiber layer (NFL) of the chicken retina was studied quantitatively and morphologically at 17 positions along seven radially arranged bands from the dorsal tip of the pecten oculi using electron microscopy. The number of nerve fiber...
Hiroshi Kitagawa, Yuko Kano, Hiromi Shimakawa, Fumitaka Goto, Fumitaka Goto, Tomoya Ogawa, Tomoya Ogawa, Hidetoshi Okabe, Kazuyuki Sugahara
Glycobiology   9 697-703   1999年7月
We recently discovered a novel α-N-acetylgalactosaminyl-transferase in fetal bovine serum and also in mouse mastcytoma cells, which catalyzed the transfer of an α-GalNAc residue to the linkage tetrasaccharide-serine, GlcAβ1-3Galβ1-3Galβ1-4Xylβ1-O-...
Satomi Nadanaka, Hiroshi Kitagawa, Fumitaka Goto, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Kazuyuki Sugahara
Biochemical Journal   340 353-357   1999年6月
α-Thrombomodulin (α-TM) with a truncated glycosaminoglycan-protein linkage tetrasaccharide, GlcAβ1-3Galβ1-3Galβ1-4Xyl, was tested as an acceptor together with a sugar donor, UDP-N-[ 3 H]acetylgalactosamine, using a cell-free enzyme system prepared...
Hiroshi Kitagawa, Hiromi Shimakawa, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   274 13933-13937   1999年5月
We previously demonstrated a unique α-N- acetylgalactosaminyltransferase that transferred N-acetylgalactosamine (GalNAc) to the tetrasaccharide-serine, GlcAβ1-3Galβ1-3Galβ1-4Xylβ1-O- Ser (GlcA represents glucuronic acid), derived from the common g...
Yuko Mizushima, Yuko Mizushima, Yukio Amano, Hiroshi Kitagawa, Kenji Ogata
Journal of Pharmacology and Experimental Therapeutics   288 849-857   1999年2月
Leflunomide, a drug being developed for use in the treatment of rheumatoid arthritis, was evaluated in an ovalbumin (OVA)induced rat type 1 allergy model. In a dose of 1 mg/kg/day, it strongly suppressed the formation of OVA-specific IgE, thus pre...
Takashi Takeuchi, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara
Journal of Veterinary Medical Science   61 149-154   1999年2月
The process of the disappearance of epithelial cells was examined in chicken cecal villi and follicle-associated epithelium (FAE). The apoptotic epithelial cells with intense DNA-fragmentation and their exfoliation were found in the villous tips. ...
Osamu Ishihara, Osamu Ishihara, Masahiro Saitoh, Katsuyuki Kinoshita, Hitoshi Takanashi, Yoshinori Arai, Hiroshi Kitagawa
Acta Obstetricia et Gynecologica Scandinavica   78 321-325   1999年1月
Background. To investigate the role of interleukin-1 related substances in amniotic fluid in normal term labor without intrauterine infection. Methods. Amniotic fluid samples were collected from forty-one patients with various backgrounds. A novel...
Y. Arai, H. Takanashi, H. Kitagawa, K. J. Wirth, I. Okayasu
Digestive Diseases and Sciences   44 845-851   1999年1月
Dextran sulfate sodium-induced colitis in mice has been recognized as a model for human ulcerative colitis. Using this model, we carried out a study on the preventive effect of Icatibant, a bradykinin B 2 receptor antagonist previously called HOE ...
Kae Tsutsumi, Hiromi Shimakawa, Hiroshi Kitagawa, Kazuyuki Sugahara
FEBS Letters   441 235-241   1998年12月
The cDNA and gene encoding human chondroitin 6-sulfotransferase (C6ST) have been cloned. The expression of a soluble recombinant form of the protein in COS-1 cells produced an active sulfotransferase, which used as acceptor substrates polymer chon...
Satomi Nadanaka, Hiroshi Kitagawa, Kazuyuki Sugahara
Journal of Biological Chemistry   273 33728-33734   1998年12月
Thrombomodulin (TM), a cell surface glycoprotein, is a critical mediator of endothelial anticoagulant defenses occurring both as a chondroitin sulfate proteoglycan (β-TM) and a protein (α-TM) unsubstituted by chondroitin sulfate (CS), hence its de...
Tetsuro Matsuura, Isao Narama, Kiyokazu Ozaki, Masahiko Nishimura, Tomohiro Imagawa, Hiroshi Kitagawa, Masato Uehara
Anatomy and Embryology   198 91-99   1998年9月
The knotty-tail (knt/knt) mouse has a short and knotty tail. The tail deformity is caused by a decrease in the number of caudal vertebrae and a deformity of them in the distal parr of the tail. The objective of the study was to determine how reduc...
Takashi Takeuchi, Hiroshi Kitagawa, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   193 233-239   1998年8月
The proliferation sites and cellular kinetics of villous epithelial cells and M cells in the intestine of the adult chicken have never been clarified. In this study, we determined the proliferation sites in the chicken caecum using colchicine trea...
Hiroshi Kitagawa, Yuko Tone, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Shogo Oka, Toshisuke Kawasaki, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   273 6615-6618   1998年3月
We isolated a cDNA encoding a novel glucuronyltransferase from human placenta cDNA with the use of the degenerate reverse transcriptase-polymerase chain reaction method. Degenerate primers ware designed based upon the amino acid sequence alignment...
Tetsuro Matsuura, Isao Narama, Kiyokazu Ozaki, Hiroo Nakajima, Masahiko Nishimura, Tomohiro Imagawaj, Hiroshi Kitagawa, Masato Uehara
Congenital Anomalies   38 67-79   1998年3月
Mice with short and knotty tails arose as a spontaneous mutant in an ICR strain, and they have been named knotty-tail mouse (gene symbol; knt). They also have a minor anomaly of the cervical vertebrae, especially in the axis. In this study, the ce...
Masato Uehara, Tomohiro Imagawa, Hiroshi Kitagawa
Journal of Veterinary Medical Science   60 773-775   1998年1月
The present study was designed to reveal whether astrocytic activation following axotomy causes a numerical increase of nuclear bodies (NBs) in chicken astrocytes. Astrocytes in the spinal cord were activated by a unilateral spinal nerve transecti...
Hiroshi Kitagawa, Hiroshi Kitagawa, Yoshitoshi Hiratsuka, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   192 293-298   1998年1月
In order to clarify the fundamental structure of the host defence mechanism in chicken caeca, a detailed analysis of the distribution of lymphoid nodules (LNs) was carried out on longitudinal sections of both the mesenteric (side of the ileocaecal...
Yoshinori Arai, Yoshinori Arai, Hitoshi Takanashi, Hiroshi Kitagawa, Isao Okayasu
Cytokine   10 890-896   1998年1月
Dextran sulfate sodium (DSS)-induced colitis in mice has been recognized as a model for human ulcerative colitis. Using this model, the effects of anti-murine interleukin 1β (IL-1β) antibodies (anti-muIL-1β) and recombinant murine IL-1 receptor ty...
K. Tsuchida, H. Kitagawa, K. Sugahara
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   43 2594-2601   1998年1月
Hiroshi Kitagawa, Kae Tsutsumi, Yuko Tone, Kazuyuki Sugahara, Kazuyuki Sugahara
Journal of Biological Chemistry   272 31377-31381   1997年12月
Developmentally regulated and cell type-specific expression of distinct sulfated glycosaminoglycan structures on cell surface proteoglycans is increasingly recognized as providing information relevant to cell-cell interactions and differentiation ...
Osamu Ishihara, Hitomi Numari, Masahiro Saitoh, Yoshinori Arai, Hitoshi Takanashi, Hiroshi Kitagawa, Katsuyuki Kinoshita
Advances in Experimental Medicine and Biology   433 419-422   1997年12月
H. Kitagawa, K. Sugahara
Connective Tissue   29 267-272   1997年12月
The diverse functions ascribed to chondroitin sulfate (CS) and characteristic CS chains are expressed in a tissue- and cell type-specific manner, suggesting that the sulfation and polymerization of the CS chains are strictly regulated. Nevertheles...
Hiroshi Kitagawa, Mika Oyama, Kimiko Masayama, Yu Yamaguchi, Kazuyuki Sugahara, Kazuyuki Sugahara
Glycobiology   7 1175-1180   1997年12月
Decorin is a small fibroblast proteoglycan consisting of a core protein and a single chondroitin/dermatan sulfate chain. The structure of the carbohydrate-protein linkage region of the recombinant decorin expressed in Chinese hamster ovary cells w...
Kerstin Lidholt, Maria Fjelstad, Ulf Lindahl, Fumitaka Goto, Tomoya Ogawa, Hiroshi Kitagawa, Kazuyuki Sugahara
Glycoconjugate Journal   14 737-742   1997年10月
Two glycosaminoglycan-protein linkage tetrasaccharide-serine compounds, GlcAβ1-3Galβ1-3Galβ1-4Xylβ1-O-Ser and GlcAβ1-3Gal(4-O-sulfate)β1-3Galβ1-4Xylβ1-O-Ser, were tested as hexosamine accepters, using UDP-[ 3 H]GlcNAc and UDP-[ 3 H]GalNAc as sugar...
Hiroshi Kitagawa, Miho Ujikawa, Kae Tsutsumi, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Kazuyuki Sugahara, Kazuyuki Sugahara
Glycobiology   7 905-911   1997年10月
We studied a glucuronyltransferase involved in chondroitin sulfate (CS) biosynthesis in a preparation obtained from fetal bovine serum by heparin-Sepharose affinity chromatography. This enzyme transferred GlcA from UDP-GlcA to the nonreducing GalN...
Hiroshi Kitagawa, Kae Tsutsumi, Miho Ujikawa, Fumitaka Goto, Jun Ichi Tamura, Klaus W. Neumann, Tomoya Ogawa, Tomoya Ogawa, Kazuyuki Sugahara
Glycobiology   7 531-537   1997年6月
The relationship between sulfation and polymerization in chondroitin sulfate (CS) biosynthesis has been poorly understood. In this study, we investigated the specificity of bovine serum UDP-GalNAc: CS β-GalNAc transferase responsible for chain elo...
Hiroshi Kitagawa, Yukako Tanaka, Shuhei Yamada, Nobuko Seno, Stuart M. Haslam, Howard R. Morris, Anne Dell, Kazuyuki Sugahara
Biochemistry   36 3998-4008   1997年4月
Novel sulfated tetrasaccharide structures containing 3-O-sulfated GlcA were isolated recently from king crab cartilage chondroitin sulfate K [Sugahara, K., Tanaka, Y., Yamada, S., Seno, N., Kitagawa, H., Haslam, S. M., Morris, H. R., and Dell, A. ...
Takahiro Kanno, Namiko Koyanagi, Youli Katoku, Akie Yonekubo, Takaji Yajima, Takaji Yajima, Tamotsu Kuwata, Hiroshi Kitagawa, Etsumori Harada
Journal of Pediatric Gastroenterology and Nutrition   24 242-252   1997年3月
Background: Milk formulas for artificially reared (AR) rat pups are mostly based on complex cow's milk products, prepared by laborious and time- consuming processes. The aim of this study was to develop a simplified procedure for preparing a refin...
Tetsuro Matsuura, Isao Narama, Tetsu Nishikawa, Masahiko Nishimura, Tomohiro Imagawa, Hiroshi Kitagawa, Masato Uehara
Annals of Anatomy   179 277-283   1997年1月
Morphological and morphometric examinations were conducted on skeletons of knotty-tail (knt/knt) mouse, a new autosomal recessive mutant. The knt/knt mice have short and knotty tails. The number of caudal vertebrae is reduced and their deformed ca...
Hiroshi Kitagawa, Hiroshi Kitagawa, Tomohiro Imagawa, Masato Uehara
Journal of Anatomy   189 667-672   1996年12月
A peculiar structure, observed as a dome-like protrusion at the apex of the caecum, was investigated macroscopically and histologically in healthy White Leghorn chickens. It was hemispheric or spherical in shape and as it consisted of a lumen with...
Kazuyuki Sugahara, Yukako Tanaka, Shuhei Yamada, Nobuko Seno, Hiroshi Kitagawa, Stuart M. Haslam, Howard R. Morris, Anne Dell
Journal of Biological Chemistry   271 26745-26754   1996年11月
We prepared a series of oligosaccharides from king crab cartilage chondroitin sulfate K after exhaustive digestion with testicular hyaluronidase, and determined the structures of four tetrasaccharides and a pentasaccharide by fast atom bombardment...
Masato Uehara, Tomohiro Imagawa, Hiroshi Kitagawa
Journal of Anatomy   188 661-669   1996年7月
Hyalocytes in the pecten oculi and ciliary body of adult chickens and their response to Escherichia coli were investigated by transmission and scanning electron microscopy and the inflammatory response following the intravitreous injection of coll...
H. Kitagawa, M. Ujikawa, K. Sugahara
Journal of Biological Chemistry   271 6583-6585   1996年4月
Bovine, rat, and chicken UDP-GlcA:chondroitin glucuronyltransferase activities in sera during prenatal and postnatal development were systematically measured with polymeric chondroitin as an exogenous acceptor and with UDP-[ 14 C]GlcA as a donor. ...
Hiroyuki Yamada, Yoshinori Kawabata, Koji Ohtomo, Shouichi Sakamoto, Yutsuki Nakajima, Hiroshi Kitagawa, Isamu Sugawara
Japanese Journal of Lung Cancer   36 135-137   1996年4月
In order to examine whether the antibody PC47H is useful to detect differentiation toward pulmonary adenocarcinoma, immunohistochemical examinations were undertaken comparing the results for antibody for CEA. Furthermore, antibodies for lactoferri...
Eric R. Sjoberg, Hiroshi Kitagawa, Hiroshi Kitagawa, John Glushka, Herman Van Halbeek, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   271 7450-7459   1996年3月
A cDNA encoding a novel sialyltransferase has been isolated employing the polymerase chain reaction using degenerate primers to conserved regions of the sialylmotif that is present in all eukaryotic members of the sialyltransferase gene family exa...
Tomohiro Imagawa, Hiroshi Kitagawa, Masato Uehara
Journal of Anatomy   188 149-156   1996年3月
Nerve fibres and their connections with chromaffin cells in the carp head kidney were studied by light and electron microscopy. Some nerve bundles entered the head kidney from the dorsal aspect along veins. Many unmyelinated axons emerged from the...
Hiroshi Kitagawa, Hiroshi Kitagawa, Marie Geneviève Mattei, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   271 931-938   1996年1月
In this report we describe the chromosome mapping and genomic organization of the human Galβ1,3GalNAc/Galβ1,4GlcNAc α2,3-sialyltransferase gene. The gene is localized to human chromosome 11(q23-q24) by in situ hybridization of metaphase chromosome...
Osamu Ishihara, Hitomi Numari, Masahiro Saitoh, Yoshinori Arai, Hitoshi Takanashi, Hiroshi Kitagawa, Katsuyuki Kinoshita
Prostaglandins   52 199-208   1996年1月
Previous reports revealed that interleukin-1(IL-1) was involved in the process of premature labor in the cases with intrauterine infection. However, the roles of the cytokine in normal spontaneous labor remain uncertain. The present studies aimed ...
Mark A. Williams, Hiroshi Kitagawa, Arun K. Datta, James C. Paulson, James C. Jamieson
Glycoconjugate Journal   12 755-761   1995年12月
Values of K m were determined for three purified sialyltransferases and the corresponding recombinant enzymes. The enzymes were Galβ1-4GlcNAc α2-6sialyltransferase and Galβ1-3(4)GlcNAc α2-3sialyltransferase from rat liver; these enzymes are respo...
H. Kato, R. Matsuo, O. Komiyama, T. Tanaka, M. Inazu, H. Kitagawa, T. Yoneda, T. Yoneda
Gerontology   41 20-27   1995年1月
Osteoporosis seen in aged individuals is represented by the reduced bone mass most likely resulting from decreased bone formation by osteoblasts. To examine whether aging causes a decrease in osteoblast activity, calvarial osteoblasts were iso lat...
M. Katoh, K. Kitamura, H. Kitagawa
Bone   16 97-102   1995年1月
Unfractionated mouse long-bone cells prestimulated with rat parathyroid hormone (PTH) for 7 days (PTH-prestimulated long-bone cells; PTH-psLB cells) contained about 20% tartrate-resistant acid phosphatase (TRAP)-positive mononuclear cells and abou...
Hiroshi Kitagawa, Kazunori Tsuchida, Miho Ujikawa, Kazuyuki Sugahara
Journal of Biochemistry   117 1083-1087   1995年1月
We report the occurrence, in bovine serum of a soluble form, of N-acetylgalactosaminyl-transferase activity, which is involved in chondroitin sulfate biosynthesis, and we describe a simple assay method for the enzyme. Chondroitin with the general ...
Hiroshi Kitagawa, Akiko Kinoshita, Kazuyuki Sugahara
Analytical Biochemistry   232 114-121   1995年1月
A series of disaccharides derived from chondroitin sulfate and heparin/heparan sulfate were derivatized at their reducing ends with the fluorophore 2-amino-acridone. The resulting labeled compounds derived from chondroitin sulfate or heparin/hepar...
H. Kitagawa, Y. Tanaka, K. Tsuchida, F. Goto, T. Ogawa, K. Lidholt, U. Lindahl, K. Sugahara
Journal of Biological Chemistry   270 22190-22195   1995年1月
During the course of a study to elucidate the role of modification of the common polysaccharide-protein linkage structure, GlcAβ1-3Galβ1-3Galβ1- 4Xylβ1-O-Ser, in biosynthetic sorting mechanisms of the different sulfated glycosaminoglycan chains, a...
T. Imagawa, H. Kitagawa, M. Uehara
Journal of Anatomy   185 521-528   1994年12月
The ultrastructural features of blood vessels were examined by transmission and scanning electron microscopy in the perfused and nonperfused head kidney of the carp. They consisted mainly of the sinusoidal capillaries, arterioles, veins and portal...
Hiroshi Kitagawa, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   269 17872-17878   1994年7月
Cell type-specific expression of specific carbohydrate structures on cell surface glycoproteins and glycolipids is increasingly recognized for providing information relevant to cell-cell interactions in developing and adult organisms. Sialyltransf...
Hiroshi Kitagawa, James C. Paulson, James C. Paulson
Journal of Biological Chemistry   269 1394-1401   1994年1月
Sialyltransferases are a family of 10-12 enzymes that catalyze the transfer of sialic acid to carbohydrate groups of glycoproteins and glycolipids. Three sialyltransferase cDNAs have been cloned, revealing a highly conserved sialylmotif in the cat...
Tomohiro Imagawa, Yasuhiro Kon, Hiroshi Kitagawa, Yoshiharu Hashimoto, Masato Uehara, Makoto Sugimura
Annals of Anatomy   176 175-179   1994年1月
Appendices colli (App. colli) were investigated by anatomical and histological methods in the goat. App. colli were composed of elastic cartilage located at central and the skin covering the cartilage, which included arterioles along the cartilage...
Hiroshi Kimoto, Kazuyuki Kitamura, Kazuyuki Kitamura, Tetsuo Sudo, Tetsuo Sudo, Toshio Suda, Toshio Suda, Yasuki Ogawa, Yasuki Ogawa, Hiroshi Kitagawa, Hiroshi Kitagawa, Masaru Taniguchi, Masaru Taniguchi, Toshitada Takemori
International Immunology   5 1535-1540   1993年12月
Immature hemopoietic cell lines were established by transforming fetal thymocytes in vitro with a ts mutant of Abelson murine leukemia virus. They are positive for c-kit and IL-2Rα but negative for lineage specific markers. Their TCR and Ig heavy ...
H. Kitagawa, J. C. Paulson
Biochemical and Biophysical Research Communications   194 375-382   1993年7月
Here we report the cDNA sequence of human Galβ1,3(4)GlcNAc α2,3-sialyltransferase. The cDNA was isolated from a human placental cDNA library by screening with a 150bp probe generated by PCR using degenerate primers based on the sequences found in ...
Hiroyuki Yamada, Yoshinori Kawabata, Hiroshi Kitagawa, Shinji Itoyama, Isamu Sugawara
Acta Histochemica et Cytochemica   26 591-596   1993年1月
The localization of fucosylceramide recognized by a monoclonal antibody (MAb), PC47H, was examined immunohistochemically using normal and cancerous tissues. Immunoreactive fucosylceramide was observed in pancreas, parathyroid, submandibular gland,...
M. Tsujisaki, Y. Hinoda, S. Tokuchi, Y. Hanzawa, Y. Arimura, J. Masuya, H. Kitagawa, E. Okochi, T. Shimamura, J. Hamuro, K. Imai, A. Yachi
Journal of Immunology   150 508-516   1993年1月
Five anti-Id mAb (Ab2) were prepared from a BALB/c mouse immunized with anti-carcinoembryonic Ag (CEA) mAb MA208 (Ab1) in a syngeneic system. These anti-Id mAb appear to recognize unique idiotopes at the combining site of mAb MA208, because they w...
K. Kitamura, M. Katoh, O. Komiyama, H. Kitagawa, F. Matsubara, M. Kumegawa
Bone   14 829-834   1993年1月
We established a useful assay system for evaluating osteoclast-mediated bone resorption based on the use of unfractionated bone cells obtained from 10- to 11-day-old mice. When cells from 10 to 11 mice were treated for 7 days with rat parathyroid ...
Hiroshi Kitagawa, Hiroshi Nakada, Shigeyuki Fukui, Ikuo Funakoshi, Toshisuke Kawasaki, Ikuo Yamashina, Shin Ichi Tate, Fuyuhiko Inagaki
Journal of Biochemistry   114 504-508   1993年1月
Two novel oligosaccharides with the sialyl-Le a structure were isolated from human milk using a monoclonal antibody, MSW 113. These oligosaccharides were purified by affinity chromatography on a column of the immobilized monoclonal antibody and by...
Hisayoshi Nakamura, Hisayoshi Nakamura, Hiroyuki Yamada, Hiroshi Kitagawa, Atsuko Masunaga, Shinji Itoyama, Isamu Sugawara
Immunology Letters   37 119-122   1993年1月
The reactivity of PC47H, a monoclonal antibody (mAb) directed against fucosylceramide, with cells of lymphoid lineage was examined. Immunoreactive fucosylceramide (FC) was recognized only in pokeweed mitogen (PWM)-stimulated B blasts, plasma cells...
T. Taniguchi, H. Kitagawa, S. Yasue, S. Yanagi, K. Sakai, M. Asahi, S. Ohta, F. Takeuchi, S. I. Nakamura, H. Yamamura
Journal of Biological Chemistry   268 2277-2279   1993年1月
Activation of platelets by thrombin results in a dramatic increase in tyrosine phosphorylation on multiple cellular proteins (Ferrell, J. E., and Martin, G. S. (1988) Mol. Cell. Biol. 8, 3603-3610; Golden, A., and Brugge, J. S. (1989) Proc. Natl. ...
H. Kitagawa, H. Nakada, S. Fukui, I. Funakoshi, T. Kawasaki, S. I. Tate, F. Inagaki, I. Yamashina
Journal of Biological Chemistry   268 26541-26545   1993年1月
Oligosaccharides were released from the gangliosides of a human rectal adenocarcinoma with endoglycoceramidase (Rhodococcus sp. G-74-2) and then purified by affinity chromatography on a column of an immobilized monoclonal antibody, MSW 113. Three ...
T. Katagiri, T. Suzuki, Y. Akiyama, T. Ishibashi, K. Hara, H. Oka, T. Imai, K. Kobayashi, H. Kitagawa, S. Ohno, M. Tanaka, F. Imai, Y. Dohi
Ryumachi   32 461-467   1992年1月
A case of adult onset hypophosphatemic vitamin D resistant osteomalacia is described. A 40-year-old female who complained of thorax and lumbar pain and gait disturbance was admitted to our hospital on 7 November, 1988. The patient had hypophosphat...
ペロブスカイト型混合原子価錯体 CsAuI3 の圧力誘起相転移
北川 宏, 小島憲道
固体物理   27 217-230   1992年
T. Manabe, M. Yamashita, T. Kawashima, H. Okamoto, H. Kitagawa, T. Mitani, K. Toriumi, H. Miyamae, K. Inoue, K. Yakushi,
Optical Probes of Conjugated Polymers,   3145 106-115   1998年
三谷洋興, 北川 宏, 森井克行
日本結晶学会誌   40 83-89   1998年
三谷 洋興, 北川 宏, 中筋 一弘,
高圧力の科学と技術   10 42-49   2000年
金属ナノ粒子の水素吸蔵
北川宏、山内美穂
特集/ナノ粒子応用技術の新展開, 化学工業,   55 954-959   2004年
水素の科学を担うナノ錯体
北川 宏
金属元素が拓く21 世紀の新しい化学の世界,   138-148   2004年
10 族金属錯体、Pd, Pt
北川 宏
第5版実験化学講座22「金属錯体、遷移金属クラスタ-」   120-130   2004年
Property of Size Changing Palladium
M. Yamauchi and H. Kitagawa
Kagaku   61 72-73   2006年
Study on Structural Change of Pd Nanoparticles with Hydrogen Absorption / Desorption Process
H. Kobayashi, M. Yamauchi, H. Kitagawa, M. Takata
Spring-8 Research Frontiers   90-91   2006年
Caught in a Trap
M. Takata, H. Kitagawa
Riken Research   3 1-2   2008年
Nano-Alloy Based Hydrogen Storage Materials: Characteristics and Development Trends
M. Yamauchi, H. Kitagawa
工業材料   56 26-31   2008年
H. Nakada, Y. Numata, M. Inoue, N. Tanaka, H. Kitagawa, I. Funakoshi, S. Fukui, I. Yamashina
Journal of Biological Chemistry   266 12402-12405   1991年9月
To determine the epitopic structure for an anti-GalNAcα-Ser(Thr) (anti-Tn) monoclonal antibody, MLS 128, asialo-ovine submaxillary mucin was digested with various proteases, and the digests were fractionated by immunoaffinity column chromatography...
Hiroshi Nakada, Mizue Inoue, Nobuhiro Tanaka, Yoshito Numata, Hiroshi Kitagawa, Shigeyuki Fukui, Ikuo Yamashina
Biochemical and Biophysical Research Communications   179 762-767   1991年9月
Expression of the Tn antigen on a T-lymphoid cell line, Jurkat, was investigated using an anti-Tn monoclonal antibody, MLS 128. Immunoprecipitation or immunoaffinity chromatography of a lysate of Jurkat cells led to the isolation of a 120 kDa glyc...
Hiroshi Kitagawa, Hiroshi Nakada, Shigeyuki Fukui, Toshisuke Kawasaki, Ikuo Yamashina
Biochemical and Biophysical Research Communications   178 1429-1436   1991年8月
Oligosaccharides with the sialyl-Le a structure have been isolated on an affinity column of a monoclonal antibody, MSW 113, from mucin-type glycoproteins derived from the surfaces of SW 1116 and LS 180 cells, and their secretions. The oligosacchar...
Y. Kon, Y. Hashimoto, H. Kitagawa, M. Sugimura, K. Murakami
Journal of Anatomy   176 23-33   1991年7月
Renin-containing cells in fetal adrenal glands of the mouse were investigated with the protein A-gold immunocytochemical technique. On Day 14 of gestation, a small number of specific granules were weakly immunoreactive and were distributed in the ...

書籍等出版物

 
金属ナノ粒子の水素吸蔵
小林 浩和、山内 美穂、北川 宏
有機貯蔵材料とナノ技術-水素社会に向けて-, シーエムシー出版, 42-59   2007年   
プロトン伝導性金属錯体
山田鉄兵、北川 宏
金属錯体の現代物性化学,三共出版 362-375   2008年   
白金混合原子価錯体の次元クロスオーバー領域に現れる特異な電荷整列
小林厚志、北川 宏
金属錯体の現代物性化学,三共出版 356-362   2008年   
無限錯体による電子・プロトン移動
北川 宏
超分子金属錯体 三共出版, 265-279   2009年   

Works

 
水素吸蔵ポリマーの創製
2000年

競争的資金等の研究課題

 
有機遷移金属複合系電荷移動錯体の物性研究
ペロブスカイト型混合原子価原子価化合物の物性探索
水素吸蔵ポリマーの創製
水素吸蔵物質の開発
プロトン伝導体の開発