大村智 ((]J1055[)MURA Satoshi) - マイポータル

基本情報

所属: 北里大学北里生命科学研究所教授

学位: 理学修士(東京理科大学)
薬学博士(東京大学)
理学博士(東京理科大学)

J-GLOBAL ID: 200901028044834774
researchmap会員ID: 1000145503

研究キーワード

研究分野

学歴

- 1963年

東京理科大学, 理学研究科, 化学
- 1963年

東京理科大学

委員歴

1981年

日本生化学会, 評議員
1976年 - 1977年

日本細菌学会, 評議員

受賞

MISC

443

Synthesis and biological evaluation of novel 4 ''-alkoxy avermectin derivatives

K Nagai, K Shiomi, T Sunazuka, A Harder, A Turberg, S Omura

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14(16) 4135-4139 2004年8月
Absolute stereochemistries and total synthesis of (+)-arisugacins A and B, potent, orally bioactive and selective inhibitors of acetylcholinesterase

T Sunazuka, M Handa, K Nagai, T Shirahata, Y Harigaya, K Otoguro, Kuwajima, I, S Omura

TETRAHEDRON 60(36) 7845-7859 2004年8月
Selective inhibition of bleomycin-induced G2 cell cycle checkpoint by simaomicin alpha

M Arai, H Sato, H Kobayashi, M Suganuma, T Kawabe, H Tomoda, S Omura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317(3) 817-822 2004年5月
Molecular mechanisms of anti-inflammatory action of erythromycin in human bronchial epithelial cells: Possible role in the signaling pathway that regulates nuclear factor-kappa B activation

M Desaki, H Okazaki, T Sunazuka, S Omura, K Yamamoto, H Takizawa

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 48(5) 1581-1585 2004年5月
Total synthesis of (-)-borrelidin

T Nagamitsu, D Takano, T Fukuda, K Otoguro, Kuwajima, I, Y Harigaya, S Omura

ORGANIC LETTERS 6(11) 1865-1867 2004年5月
Streptomyces scabrisporus sp nov.

Ping, X, Y Takahashi, A Seino, Y Iwai, S Omura

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 54(2) 577-581 2004年3月
Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120

H Chiba, J Inokoshi, H Nakashima, S Omura, H Tanaka

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 316(1) 203-210 2004年3月
Synthesis of 4 ''-alkoxy avermectin derivatives using rhodium carbenoid-mediated O-H insertion reaction

K Nagai, T Sunazuka, S Omura

TETRAHEDRON LETTERS 45(12) 2507-2509 2004年3月
Taxonomy and secondary metabolites of Pseudobotrytis sp. FKA-25

Yuichi Yamaguchi, Rokuro Masuma, Yong-Pil Kim, Ryuji Uchida, Hiroshi Tomoda, Satoshi Omura

Mycoscience 45(1) 9-16 2004年2月25日
Enantioselective preparation of asymmetrically protected 2-propanoyl-1,3-propanediol derivatives: toward the total synthesis of Kazusamycin A

N Arai, N Chikaraishi, M Ikawa, S Omura, Kuwajima, I

TETRAHEDRON-ASYMMETRY 15(4) 733-741 2004年2月
Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness

AT Lada, M Davis, C Kent, J Chapman, H Tomoda, S Omura, LL Rudel

JOURNAL OF LIPID RESEARCH 45(2) 378-386 2004年2月
Binding site for fungal beta-lactone hymeglusin on cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase

H Tomoda, N Ohbayashi, Y Morikawa, H Kumagai, S Omura

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1636(1) 22-28 2004年2月
New beauvericins, potentiators of antifungal miconazole activity, produced by Beauveria sp. FKI-1366. I. Taxonomy, fermentation, isolation and biological properties

Takashi Fukada, Masayoshi Arai, Yuichi Yamaguchi, Rokurou Masuma, Hiroshi Tomoda, Satoshi Õmura

Journal of Antibiotics 57(2) 110-116 2004年2月
Antiparasitic agents produced by microorganisms.

Proc. Japan Acad., Ser. B 80(6) 245-258 2004年
Fungerin, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of microtubule polymerization

Yukio Koizumi, Masayoshi Arai, Hiroshi Tomoda, Satoshi Omura

Journal of Antibiotics 57(7) 415-420 2004年
In vitro and in vivo antikmalarial activities of a carbohydrate antibiot, prumycin, against drug-resistant strains of plasmodia.

J. Antibiot. 57(6) 400-402 2004年
Chemical constitutents of Erythrina suberosa.

Nature Medicine 58-84 2004年
In vitro antimalarial activiy of biflavonoids from-Wikstroemia indica.

Planta Med. (70) 77-79 2004年
Cell-based screening strategy in the search for bioactive microbial secondary metabolites. Utilization of microbial and animal acells with special functionas.

Shigeo IWASAKI, Satoshi OMURA

Proc. Japan Acad. Ser. B 80(2) 54-73 2004年
New beauvericins, potentiators of antifungal miconazole activity, produced by Beauveria sp. FKⅠ-1366. Ⅱ. Structure elucidation.

TAKASHI FUKUDA, MASAYOSHI ARAI, HIROSHI TOMODA, SATOSHI OMURA

J. Antibiot 57(2) 117-124 2004年

もっとみる

書籍等出版物

Macrolide Antibiotic-Chemistry, Biology, and Practice

Academic Press 2002年
Macrolide Antibiotic-Chemistry, Biology, and Practice

Academic Press 2002年
Screening for inhibitors of lipid metabolism.

Enzyme Technologies for Pharmaceutical and Biotechnological Application. 2001年
Screening for inhibitors of lipid metabolism.

Enzyme Technologies for Pharmaceutical and Biotechnological Application. 2001年
Screening of Novel Receptor-Active Compounds of Microbial Origin.

Biotechnology 1997年
The Search for Bioactive Complunds from Microorganisms.

SpringerVerlag New York 1992年
Macrolide Antibiotics-Chemistry, Biology and Practice

Academi Press 1984年

大村智

基本情報

研究キーワード

研究分野

学歴

委員歴

受賞

MISC

書籍等出版物

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

産業財産権

メニュー