熊谷直樹 (Naoki Kumagai) - マイポータル - researchmap

基本情報

学位: 医学博士(慶應義塾大学)

J-GLOBAL ID: 200901076866270362
researchmap会員ID: 1000145584

研究キーワード

4

研究分野

2

経歴

15

2004年

- 慶應義塾大学医学部客員助教授
2004年

- Keio University,Dept of Medicine,Associated
2000年

- 北里大学医学部非常勤講師
2000年

- Kitasato University,Dept of Medicine,Assistant
1999年

- 慶應義塾大学医学部客員講師
1999年

- Keio University,Dept of Medicine,Assistant
1994年

- 北里大学薬学部非常勤講師
1994年

- Kitasato University the Collage of pharmacy,
1985年 - 1987年

トロント大学医学部免疫学教室助手
1985年 - 1987年

Toronto University,Dept.of Immunology,
1981年 - 1984年

慶應義塾大学医学部内科助手
1981年 - 1984年

Keio University,Research Assistant
Professor
Assistant Professor
Research Fellow

学歴

2

- 1977年

慶應義塾大学, 医学部
- 1977年

慶應義塾大学

委員歴

1

1994年

日本肝臓学会東部会, 評議員

受賞

1

2003年

Hepatology Research賞

MISC

44

Complexity of the HVR-1 quasispecies and disease activity in patients with hepatitis C

N. Kumagai, F. Kaneko, S. Tsunematsu, K. Tsuchimoto, S. Tada, H. Saito, T. Hibi

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 37(7) 566-572 2007年7月
Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

K Tomita, G Tamiya, S Ando, K Ohsumi, T Chiyo, A Mizutani, N Kitamura, K Toda, T Kaneko, Y Horie …

GUT 55(3) 415-424 2006年3月
Down-regulation of matrix-invasive potential of human liver cancer cells by type I interferon and a histone deacetylase inhibitor sodium butyrate

International Journal of Oncology 24, 837-845 2004年
Polymorphism of NSSB protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: a pilot study

Journal of Viral Hepatitis 11, 225-235 2004年
Down-regulation of matrix-invasive potential of human liver cancer cells by type I interferon and a histone deacetylase inhibitor sodium butyrate

International Journal of Oncology 24, 837-845 2004年
Polymorphism of NSSB protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: a pilot study

Journal of Viral Hepatitis 11, 225-235 2004年
Differential induction of serun interleukin-6-and-12 by interferon-α and β administration in chronic hepatitis C patients.

Hepatol Res 27, 101-108 2003年
Clinical usefulness of edaravone for acute liver injury

J. Gastroen Hepatol 18, 851-857 2003年
Differential induction of serun interleukin-6-and-12 by interferon-α and β administration in chronic hepatitis C patients.

Hepatol Res 27, 101-108 2003年
Clinical usefulness of edaravone for acute liver injury

J. Gastroen Hepatol 18, 851-857 2003年
Inhibition of growth of human hepatoma cells by dual-function antisense IL-6 oligonucleotides

Hepatology Research 22, 119-126 2002年
Inhibition of growth of human hepatoma cells by dual-function antisense IL-6 oligonucleotides

Hepatology Research 22, 119-126 2002年
Anti-fibrogenic effect of an angiotensin converting enzyme inhibitor on chronic carbon tetrachloride-induced hepatic fibrosis in rats

Hepatology Research 21, 147-158 2001年
Th1and Th2 cytokines differentially regulate the transformation of kupffer cells into multinucleated giant cells but similarly enhance the kupffer cell-induced hepatic stellate cell proliferation

Hepatology Research 201, 193-206 2001年
Anti-fibrogenic effect of an angiotensin converting enzyme inhibitor on chronic carbon tetrachloride-induced hepatic fibrosis in rats

Hepatology Research 21, 147-158 2001年
Th1and Th2 cytokines differentially regulate the transformation of kupffer cells into multinucleated giant cells but similarly enhance the kupffer cell-induced hepatic stellate cell proliferation

Hepatology Research 201, 193-206 2001年
Reduced in vitro immunoglobulin secretion from peripheral blood mononuclear cells in responders to high-dose interferon-alpha 2b treatment for chronic hepatitis C

K Atsukawa, H Saito, H Ebinuma, T Morizane, M Takahashi, T Ohishi, N Kumagai, K Tsuchimoto, H Ishii

HEPATO-GASTROENTEROLOGY 47(36) 1685-1690 2000年11月
Up-regulation of E-cadherin and beta-catenin in human hepatocellular carcinoma cell lines by sodium butyrate and interferon-alpha

T Masuda, H Saito, F Kaneko, K Atsukawa, M Morita, H Inagaki, N Kumagai, K Tsuchimoto, H Ishii

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 36(6) 387-394 2000年6月
Induction of hepatic stellate cell proliferation by LPS-stimulated peripheral blood mononuclear cells from patients with liver cirrhosis

K Toda, N Kumagai, K Tsuchimoto, H Inagaki, T Suzuki, T Oishi, K Atsukawa, H Saito, T Morizane, T Hibi …

JOURNAL OF GASTROENTEROLOGY 35(3) 214-220 2000年3月
Immunological and virological predictors of outcome during interferon-alpha therapy of chronic hepatitis C

H Saito, H Ebinuma, Satoh, I, S Miyaguchi, S Tada, N Iwabuchi, N Kumagai, K Tsuchimoto, T Morizane, H Ishii

JOURNAL OF VIRAL HEPATITIS 7(1) 64-74 2000年1月

もっとみる

書籍等出版物

3

(]G0004[)各疾患-肝臓

内科実地診療必携朝倉書店 1999年
Changes in the sensitivity to LAK lysis of cultured human hepatoma cells induced by cytokines.

Frontiers of Mucosal Immunology 1991年
Changes in the sensitivity to LAK lysis of cultured human hepatoma cells induced by cytokines.

Frontiers of Mucosal Immunology 1991年

所属学協会

5

共同研究・競争的資金等の研究課題

6