2009年2月
Effects of chronic ingestion of catechin-rich green tea on hepatic gene expression of gluconeogenic enzymes in rats
BIOMEDICAL RESEARCH-TOKYO
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- 巻
- 30
- 号
- 1
- 開始ページ
- 25
- 終了ページ
- 29
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.2220/biomedres.30.25
- 出版者・発行元
- BIOMEDICAL RESEARCH PRESS LTD
Normal rats were given catechin-rich green tea as drinking fluid and the effects on hepatic gene expression were examined. The results of DNA microarray analysis and quantitative real-time reverse transcription-polymerase chain reaction indicated the down-regulated expression of genes for glucose-6-phosphatase (G6Pase) and fatty acid synthase, and the up-regulated expression of peroxisome proliferator activated receptor cc in the rats given green tea for 4 weeks as compared with the water-given animals. One may expect anti-diabetic activity by catechin-rich green tea through its chronic down-regulatory effect on G6Pase expression.
- リンク情報
- ID情報
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- DOI : 10.2220/biomedres.30.25
- ISSN : 0388-6107
- CiNii Articles ID : 80020119823
- Web of Science ID : WOS:000263864300004