MISC

2006年6月

Transgenic mice overexpressing macrophage migration inhibitory factor (MIF) exhibit high-turnover osteoporosis

JOURNAL OF BONE AND MINERAL RESEARCH
  • Shin Onodera
  • ,
  • Satoshi Sasaki
  • ,
  • Shigeki Ohshima
  • ,
  • Norio Amizuka
  • ,
  • Minqi Li
  • ,
  • Nobuyuki Udagawa
  • ,
  • Kazuharu Irie
  • ,
  • Jun Nishihira
  • ,
  • Yoshikazu Koyama
  • ,
  • Ayako Shiraishi
  • ,
  • Harukazu Tohyama
  • ,
  • Kazunori Yasuda

21
6
開始ページ
876
終了ページ
885
記述言語
英語
掲載種別
DOI
10.1359/JBMR.060310
出版者・発行元
WILEY

The bone phenotype of mice overexpressing MIF was studies. These mice showed decreased trabecular bone, increased bone formation rate, and increased MMP-3, -9, and -13 mRNA expression in the femora and tibias. This model provides evidence of the role played by MIF in bone remodeling and balance in vivo.

Web of Science ® 被引用回数 : 36

リンク情報
DOI
https://doi.org/10.1359/JBMR.060310
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/16753018
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000237820700008&DestApp=WOS_CPL

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